RSW - TYS

$150 Find Cheap Flights from Fort Myers to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Fort Myers to Knoxville departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Fort Myers to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Fort Myers to Knoxville, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Fort Myers to Knoxville (RSW-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Fort Myers to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Fort Myers to Knoxville

Tue, Oct 14 - Tue, Oct 21
American Airlines Logo
4:44 pm - 11:07 pmRSW-TYS
6h 23m1 stop
American Airlines Logo
5:00 am - 10:18 amTYS-RSW
5h 18m1 stop
$259American Airlines
Find Deal
Wed, Oct 15 - Thu, Oct 23
Delta Logo
5:38 am - 9:00 amRSW-TYS
3h 22m1 stop
Delta Logo
8:10 pm - 12:39 amTYS-RSW
4h 29m1 stop
$279Delta
Find Deal
Mon, Oct 27 - Thu, Oct 30
Delta Logo
5:38 am - 10:45 amRSW-TYS
5h 07m1 stop
Delta Logo
5:44 am - 11:50 amTYS-RSW
6h 06m1 stop
$299Delta
Find Deal
Wed, Oct 15 - Wed, Oct 22
Delta Logo
5:38 am - 9:00 amRSW-TYS
3h 22m1 stop
Delta Logo
5:44 am - 11:50 amTYS-RSW
6h 06m1 stop
$309Delta
Find Deal
Tue, Oct 14 - Fri, Oct 24
Delta Logo
5:38 am - 10:49 amRSW-TYS
5h 11m1 stop
Delta Logo
8:10 pm - 12:39 amTYS-RSW
4h 29m1 stop
$329Delta
Find Deal
Wed, Oct 15 - Tue, Oct 21
United Airlines Logo
2:26 pm - 10:50 pmRSW-TYS
8h 24m1 stop
United Airlines Logo
8:50 am - 11:14 pmTYS-RSW
14h 24m2 stops
$334United Airlines
Find Deal
Mon, Oct 13 - Fri, Oct 24
Delta Logo
5:38 am - 9:00 amRSW-TYS
3h 22m1 stop
Delta Logo
8:10 pm - 12:39 amTYS-RSW
4h 29m1 stop
$338Delta
Find Deal
Fri, Nov 7 - Tue, Nov 11
Delta Logo
5:38 am - 9:20 amRSW-TYS
3h 42m1 stop
Delta Logo
3:51 pm - 9:34 pmTYS-RSW
5h 43m1 stop
$343Delta
Find Deal
Thu, Oct 16 - Wed, Oct 22
American Airlines Logo
7:32 pm - 11:53 pmRSW-TYS
4h 21m1 stop
American Airlines Logo
11:15 am - 3:54 pmTYS-RSW
4h 39m1 stop
$349American Airlines
Find Deal
Fri, Nov 7 - Tue, Nov 11
United Airlines Logo
6:40 pm - 11:59 pmRSW-TYS
5h 19m1 stop
United Airlines Logo
5:45 am - 2:19 pmTYS-RSW
8h 34m2 stops
$353United Airlines
Find Deal

Everything you should know

Top airlines
American Airlines
Cheapest • from $259 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 29% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 25% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$259
Overall average: $367
American Airlines
Tue 10/14Tue 10/21
RSW - TYS • 1 stop
Cheapest one-way
$150
Typical prices: $249-609
American Airlines
Thu 10/16
RSW - TYS • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Booking Insights

KAYAK's insights & trends for Fort Myers to Knoxville flights

Get data-powered insights and trends into flights from Fort Myers to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Fort Myers to Knoxville?

The average price of all round-trip flights from Fort Myers to Knoxville clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Fort Myers to Knoxville, look for departures on Wednesdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Knoxville, Wednesday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Fort Myers to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Fort Myers to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Fort Myers to Knoxville is March, where tickets cost $253 (return) on average. On the other hand, the most expensive months are June and April, where the average cost of round-trip tickets is $442 and $423 respectively.

How far in advance should I book a flight from Fort Myers to Knoxville?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Fort Myers to Knoxville, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Fort Myers to Knoxville, you should book around 4 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Good to know

Low seasonMarch
Cheapest flight$150
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Fort Myers to Knoxville

When to book flights from Fort Myers to Knoxville

Are your dates flexible? Find out the best times to travel from Fort Myers to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Fort Myers to Knoxville

  • What is the cheapest flight from Fort Myers to Knoxville?

    In the last 3 days, the lowest price for a flight from Fort Myers to Knoxville was $150 for a one-way ticket and $259 for a round-trip.

  • Do I need a passport to fly between Fort Myers and Knoxville?

    No

  • Which airports will I be using when flying from Fort Myers to Knoxville?

    Fort Myers airport is called Fort Myers SW Florida Intl and the only airport in Knoxville is Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Fort Myers to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Fort Myers to Knoxville?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Fort Myers and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Fort Myers to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Fort Myers to Knoxville are Delta and American Airlines. With an average price for the route of $346 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $327 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Fort Myers to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Fort Myers to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Fort Myers to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Fort Myers is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Fort Myers to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Fort Myers with another airline. Booking your flights between Fort Myers and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Fort Myers to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Fort Myers up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Fort Myers to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Fort Myers to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Fort Myers to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
7.9Comfort
7.3Food
8.5Crew
7.9Entertainment
8.2Boarding
Airline reviews

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

8.0 ExcellentOlaf, Sep 2025FLL - ATL
Read more Delta reviews

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

Kind staff. Snacks are small but that’s the new normal.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

Everything you need to know for your flight from Fort Myers to Knoxville

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.