United States
USD

TYS - LYS

$846 Find Cheap Flights from Knoxville to Lyon - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 19% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$846
Typical prices: $686-$1,398
United Airlines
Mon 11/5Mon 11/12
TYS - LYS • 2 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Lyon!

Cheap Flights from Knoxville to Lyon (TYS-LYS)

 

Cheap flights from Knoxville to Lyon with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Thu, Nov 5 - Thu, Nov 12
United Airlines Logo
1:55 pm - 11:05 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
15h 10m2 stops Washington, D.C. Dulles Intl Brussels Bruxelles-National
United Airlines Logo
1:40 pm - 8:54 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
37h 14m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl
$846United Airlines
Mon, Nov 16 - Thu, Nov 19
Air Canada Logo
6:45 am - 11:05 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
22h 20m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
Air Canada Logo
1:40 pm - 11:59 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
40h 19m2 stops Montreal Pierre Elliott Trudeau Intl Washington, D.C. Dulles Intl
$1,117Air Canada
Mon, Nov 16 - Thu, Nov 19
United Airlines Logo
6:45 am - 11:05 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
22h 20m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
United Airlines Logo
1:40 pm - 11:30 amLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
51h 50m2 stops Montreal Pierre Elliott Trudeau Intl Washington, D.C. Dulles Intl
$1,147United Airlines
Mon, Nov 16 - Thu, Nov 19
United Airlines Logo
6:45 am - 11:05 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
22h 20m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl
United Airlines Logo
1:40 pm - 10:44 amLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
51h 04m2 stops Montreal Pierre Elliott Trudeau Intl Newark
$1,147United Airlines
Thu, Nov 5 - Thu, Nov 12
United Airlines Logo
11:20 am - 11:05 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
17h 45m2 stops Newark Brussels Bruxelles-National
United Airlines Logo
1:40 pm - 11:59 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
16h 19m3 stops Montreal Pierre Elliott Trudeau Intl Boston Logan Intl Washington, D.C. Dulles Intl
$1,239United Airlines
Thu, Nov 5 - Thu, Nov 12
Multiple Airlines Logo
4:30 pm - 6:30 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
20h 00m3 stops Newark Munich Franz Josef Strauss Warsaw Frederic Chopin
Multiple Airlines Logo
2:50 pm - 6:46 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
33h 56m3 stops Dublin London Heathrow Chicago O'Hare Intl
$1,756Multiple Airlines
Thu, Nov 5 - Thu, Nov 12
Ethiopian Air Logo
5:45 am - 8:00 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
44h 15m3 stops Washington, D.C. Dulles Intl Addis Ababa Bole Geneva Geneve-Cointrin
Ethiopian Air Logo
7:35 pm - 7:36 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
54h 01m4 stops Geneva Geneve-Cointrin Addis Ababa Bole Rome Fiumicino Washington, D.C. Dulles Intl
$2,410Ethiopian Air
Mon, Nov 16 - Thu, Nov 19
Ethiopian Air Logo
1:55 pm - 8:00 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
60h 05m3 stops Washington, D.C. Dulles Intl Addis Ababa Bole Geneva Geneve-Cointrin
Ethiopian Air Logo
7:35 pm - 7:36 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
54h 01m4 stops Geneva Geneve-Cointrin Addis Ababa Bole Rome Fiumicino Washington, D.C. Dulles Intl
$3,011Ethiopian Air
Mon, Nov 16 - Thu, Nov 19
Ethiopian Air Logo
1:55 pm - 8:00 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
60h 05m3 stops Washington, D.C. Dulles Intl Addis Ababa Bole Geneva Geneve-Cointrin
Ethiopian Air Logo
7:35 pm - 7:36 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
54h 01m4 stops Geneva Geneve-Cointrin Addis Ababa Bole Rome Fiumicino Washington, D.C. Dulles Intl
$3,175Ethiopian Air
Mon, Nov 16 - Thu, Nov 19
Ethiopian Air Logo
1:55 pm - 8:00 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
60h 05m3 stops Washington, D.C. Dulles Intl Addis Ababa Bole Geneva Geneve-Cointrin
Ethiopian Air Logo
7:35 pm - 7:36 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
54h 01m4 stops Geneva Geneve-Cointrin Addis Ababa Bole Rome Fiumicino Washington, D.C. Dulles Intl
$3,176Ethiopian Air

Price, demand and travel trends for Knoxville to Lyon flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Knoxville to Lyon?

Round-trip flights from Knoxville to Lyon typically range from $686 to $1,398. The lowest price found in the past 5 days was $846, on United Airlines.

Find deals

Key details for Knoxville to Lyon flights

Cheapest flight

$846
Round-trip flight from Knoxville to Lyon

When to book flights from Knoxville to Lyon

Are your dates flexible? Find out the best times to travel from Knoxville to Lyon based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Lyon flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Knoxville to Lyon?

    Only Economy Class is available on flights from Knoxville to Lyon.

  • Do I need a passport to fly from Knoxville to Lyon?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Knoxville to Lyon changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $846 to $3,176. That means the highest observed fare was about 4x higher than the lowest one.

  • What car rental options are available at Lyon-Saint Exupéry Airport (LYS)?

    Lyon-Saint Exupéry Airport (LYS) hosts 5 major car rental companies, with daily rates starting from around $11 for economy cars. Top options include:

    • Rentscape
    • Alamo
    • Europcar
    • Ok Mobility
    • Enterprise Rent-A-Car

  • Which airports can I use when flying from Knoxville to Lyon?

    Flights from Knoxville to Lyon usually depart from Knoxville McGhee Tyson (TYS) and arrive at Lyon-Saint Exupéry (LYS).

  • Can I save money by using flexible dates for flights from Knoxville to Lyon?

    Yes. Flexible dates can save you up to 58% on flights from Knoxville to Lyon. Monday is the cheapest departure day at $600 round-trip on average, while Sunday is the most expensive at $1,398, a difference of $798.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Knoxville and Lyon?

    Lyon is 6 hours ahead of Knoxville (Central European Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Lyon?

    Some of the most popular sights in Lyon are Centre de congrès de Lyon, Tour Part-Dieu and Basilica Notre-Dame de Fourvière. These are among the most viewed places in Lyon on KAYAK.

Your guide to booking Knoxville to Lyon flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Sunday. On this route, Monday flights average $600, about $798 less than Sunday fares (57% savings) based on the last 12 months.

More options for your flight from Knoxville to Lyon

Complete your trip to Lyon with a hotel stay or car rental

Car rentals in Lyon
Hotels in Lyon
Vacations in Lyon