TYS - LYS

$742 Find Cheap Flights from Knoxville to Lyon - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$742
Typical prices: $1,050-$1,398
United Airlines
Fri 11/16Mon 11/19
TYS - LYS • 2 stops
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Booking Insights
Flight Deals

Cheap Flights from Knoxville to Lyon (TYS-LYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Lyon

Mon, Nov 16 - Thu, Nov 19
United Airlines Logo
5:40 pm - 12:15 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
36h 35m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
United Airlines Logo
6:30 am - 11:59 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
23h 29m2 stops Frankfurt am Main Washington, D.C. Dulles Intl
$742United Airlines
Mon, Nov 16 - Wed, Nov 18
United Airlines Logo
5:45 am - 5:55 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
30h 10m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss
United Airlines Logo
7:00 am - 7:36 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
18h 36m2 stops Brussels Bruxelles-National Washington, D.C. Dulles Intl
$743United Airlines
Mon, Nov 16 - Thu, Nov 19
United Airlines Logo
5:40 pm - 5:55 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
42h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
United Airlines Logo
1:40 pm - 11:59 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
40h 19m2 stops Montreal Pierre Elliott Trudeau Intl Washington, D.C. Dulles Intl
$1,084United Airlines
Tue, Sep 8 - Fri, Sep 11
Aer Lingus Logo
6:52 pm - 9:30 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
32h 38m2 stops Chicago O'Hare Intl Dublin
Aer Lingus Logo
10:10 am - 7:43 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
39h 33m2 stops Dublin Chicago O'Hare Intl
$1,102Aer Lingus
Mon, Nov 16 - Thu, Nov 19
United Airlines Logo
5:40 pm - 12:15 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
36h 35m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
United Airlines Logo
6:30 am - 11:59 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
23h 29m2 stops Frankfurt am Main Washington, D.C. Dulles Intl
$1,270United Airlines
Mon, Sep 7 - Fri, Sep 11
Aer Lingus Logo
7:34 am - 9:30 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
19h 56m2 stops Chicago O'Hare Intl Dublin
Aer Lingus Logo
10:10 am - 7:43 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
39h 33m2 stops Dublin Chicago O'Hare Intl
$1,377Aer Lingus
Tue, Sep 8 - Fri, Sep 11
Multiple Airlines Logo
6:00 am - 6:00 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
30h 00m2 stops Chicago O'Hare Intl Frankfurt am Main
Multiple Airlines Logo
1:55 pm - 10:49 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
38h 54m3 stops Montreal Pierre Elliott Trudeau Intl Newark Chicago O'Hare Intl
$1,447Multiple Airlines
Mon, Sep 7 - Fri, Sep 11
United Airlines Logo
5:45 am - 9:55 amTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
22h 10m2 stops Washington, D.C. Dulles Intl Montreal Pierre Elliott Trudeau Intl
United Airlines Logo
7:05 am - 10:49 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
21h 44m3 stops Frankfurt am Main Newark Chicago O'Hare Intl
$1,454United Airlines
Tue, Sep 8 - Fri, Sep 11
Brussels Airlines Logo
1:10 pm - 10:20 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
27h 10m3 stops Washington, D.C. Dulles Intl Athens Eleftherios V. Brussels Bruxelles-National
Brussels Airlines Logo
1:10 pm - 8:24 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
37h 14m3 stops Brussels Bruxelles-National Geneva Geneve-Cointrin Washington, D.C. Dulles Intl
$1,838Brussels Airlines
Mon, Sep 7 - Fri, Sep 11
Brussels Airlines Logo
1:00 pm - 10:20 pmTYS  Knoxville McGhee Tyson-LYS Lyon-Saint Exupéry
27h 20m3 stops Washington, D.C. Dulles Intl Rome Fiumicino Brussels Bruxelles-National
Brussels Airlines Logo
1:10 pm - 8:24 pmLYS  Lyon-Saint Exupéry-TYS Knoxville McGhee Tyson
37h 14m3 stops Brussels Bruxelles-National Geneva Geneve-Cointrin Washington, D.C. Dulles Intl
$1,841Brussels Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Lyon flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Lyon with more confidence.

How much is a round-trip flight from Knoxville to Lyon?

Round-trip flights from Knoxville to Lyon start at $742. Prices are below average for this route right now, with typical round-trip fares ranging from $1,050 to $1,398. The lowest price found in the past 5 days was $742 on United Airlines.

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Key details for Knoxville to Lyon flights

Cheapest flight

$742
Flight from Knoxville to Lyon

When to book flights from Knoxville to Lyon

Are your dates flexible? Find out the best times to travel from Knoxville to Lyon based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Lyon flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to Lyon?

    Flights from Knoxville to Lyon usually depart from Knoxville McGhee Tyson (TYS) and arrive at Lyon-Saint Exupéry (LYS).

  • Can I save money by using flexible dates for flights from Knoxville to Lyon?

    Yes. Being flexible with your travel dates can save you up to 58% on the Knoxville to Lyon route. Monday is the cheapest departure day at $600 round-trip on average, while Sunday is the most expensive at $1,398, a difference of $798. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Lyon?

    Some of the most popular sights in Lyon are Lyon-Part-Dieu Station, Lyon City Centre and Tour Part-Dieu. These are among the most viewed places in Lyon on KAYAK.

  • Do I need a passport to fly from Knoxville to Lyon?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Knoxville to Lyon changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $742 to $1,841. That means the highest observed fare was about 2x higher than the lowest one.

  • What is the time difference between Knoxville and Lyon?

    Lyon is 6 hours ahead of Knoxville (Central European Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Lyon-Saint Exupéry Airport (LYS)?

    Lyon-Saint Exupéry Airport (LYS) hosts 5 major car rental companies, with daily rates starting from around $11 for economy cars. Top options include:
    · Rentscape
    · Alamo
    · Ok Mobility
    · Europcar
    · Enterprise Rent-A-Car

  • How much should I expect to pay for a Knoxville to Lyon flight?

    Round-trip flights from Knoxville to Lyon range from $1,050 to $1,398, with an average of $1,258 over the past 12 months. Anything below $1,050 counts as a good deal.

Your guide to booking Knoxville to Lyon flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Monday departure instead of Sunday. On this route, Monday flights average $600 - about $798 less than Sunday (57% savings) based on the last 12 months.

Everything you need to know for your flight from Knoxville to Lyon

Information on your arrival and departure airports

Knoxville (TYS)
Lyon (LYS)