TYS - MFE

$344 Find Cheap Flights from Knoxville to McAllen

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to McAllen departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to McAllen

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to McAllen, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to McAllen, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$344
American Airlines
Fri 6/12Tue 6/16
TYS - MFE • 1 stop
Top airlines
American Airlines
Cheapest • from $344 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and McAllen. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $491 (round-trip)
Dallas (DFW)
Shortest trip • 5h 29m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to McAllen!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to McAllen (TYS-MFE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to McAllen that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to McAllen

Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
8:11 pm - 12:21 am
TYS
-
MFE
5h 10m
1 stop
American Airlines Logo
5:00 am - 1:02 pm
MFE
-
TYS
7h 02m
1 stop
$344American Airlines
Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
5:37 am - 9:59 am
TYS
-
MFE
5h 22m
1 stop
American Airlines Logo
1:47 pm - 11:59 pm
MFE
-
TYS
9h 12m
2 stops
$401American Airlines
Thu, Jun 4 - Sun, Jun 7
Multiple Airlines Logo
3:42 pm - 7:54 am
TYS
-
MFE
17h 12m
1 stop
Multiple Airlines Logo
9:04 pm - 11:39 pm
MFE
-
TYS
25h 35m
2 stops
$475Multiple Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
5:33 pm - 9:59 pm
TYS
-
MFE
5h 26m
1 stop
American Airlines Logo
5:00 am - 1:02 pm
MFE
-
TYS
7h 02m
1 stop
$527American Airlines
Thu, Jun 4 - Sun, Jun 7
American Airlines Logo
5:33 pm - 12:21 am
TYS
-
MFE
7h 48m
1 stop
American Airlines Logo
5:00 am - 11:13 am
MFE
-
TYS
5h 13m
1 stop
$561American Airlines
Mon, Jun 15 - Sun, Jun 21
American Airlines Logo
5:33 pm - 12:18 am
TYS
-
MFE
7h 45m
1 stop
American Airlines Logo
5:00 am - 11:13 am
MFE
-
TYS
5h 13m
1 stop
$595American Airlines
Mon, Jun 15 - Sun, Jun 21
Multiple Airlines Logo
2:46 pm - 4:03 pm
TYS
-
MFE
26h 17m
1 stop
Multiple Airlines Logo
9:04 pm - 7:37 pm
MFE
-
TYS
21h 33m
2 stops
$669Multiple Airlines
Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
3:40 pm - 12:21 am
TYS
-
MFE
9h 41m
2 stops
American Airlines Logo
1:47 pm - 11:59 pm
MFE
-
TYS
9h 12m
2 stops
$687American Airlines
Mon, Jun 15 - Sun, Jun 21
Multiple Airlines Logo
2:46 pm - 4:03 pm
TYS
-
MFE
26h 17m
1 stop
Multiple Airlines Logo
9:04 pm - 7:37 pm
MFE
-
TYS
21h 33m
2 stops
$719Multiple Airlines
Mon, Jun 15 - Sun, Jun 21
Delta Logo
3:54 pm - 11:59 pm
TYS
-
MFE
9h 05m
2 stops
Delta Logo
5:20 am - 3:19 pm
MFE
-
TYS
8h 59m
2 stops
$824Delta
Booking Insights

KAYAK's insights & trends for Knoxville to McAllen flights

Get data-powered insights and trends into flights from Knoxville to McAllen to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to McAllen?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 3 days.

In the past 3 days, the cheapest round-trip tickets from Knoxville to McAllen were found on American Airlines ($344) and Delta ($824).

Find deals

Good to know

Cheapest flight$344
Flight from Knoxville to McAllen

When to book flights from Knoxville to McAllen

Are your dates flexible? Find out the best times to travel from Knoxville to McAllen based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to McAllen

  • What is the cheapest flight from Knoxville to McAllen?

    In the last 3 days, the lowest price for a flight from Knoxville to McAllen was $344 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and McAllen?

    No

  • Which aircraft models fly most regularly from Knoxville to McAllen?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to McAllen?

    oneworld is the only airline alliance operating flights between Knoxville and McAllen.

  • How does KAYAK find such low prices on flights from Knoxville to McAllen?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to McAllen.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to McAllen?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to McAllen from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to McAllen?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to McAllen with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and MFE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to McAllen?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to McAllen from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to McAllen

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to McAllen. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to McAllen? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11644 reviews
7.2Comfort
6.4Food
7.5Boarding
6.9Entertainment
7.9Crew
Airline reviews

Seat comfort was poor (no lumbar or lower back support).

8.0 ExcellentAnonymous, May 2026
PIT - DFW
Read more American Airlines reviews

Seat comfort was poor (no lumbar or lower back support).

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Got home at 3am after deboarding the plane. No compensation offered by American

Flights on time w/o delays. However, my baggage was damaged. Ground crew, throws baggage from plane to the baggage carrier, carelessly.

Business class was very good, one of my best flights

American flight was diverted and delayed but app didn’t show that information so I wasn’t able to change my connection until the last min.

Everything you need to know for your flight from Knoxville to McAllen

Information on your arrival and departure airports

Knoxville (TYS)
McAllen (MFE)