TYS - MFE

$379 Find Cheap Flights from Knoxville to McAllen - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$379
Typical prices: $401-$601
American Airlines
Sun 9/2Thu 9/6
TYS - MFE • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and McAllen. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
June
Cheapest • 10% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $521 (round-trip)
Houston George Bush Intcntl (IAH)
Shortest trip • 5h 18m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Knoxville to McAllen (TYS-MFE)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to McAllen

Wed, Sep 2 - Sun, Sep 6
American Airlines Logo
11:49 am - 3:33 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
4h 44m1 stop Dallas/Fort Worth
American Airlines Logo
7:00 am - 12:56 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
4h 56m1 stop Dallas/Fort Worth
$379American Airlines
Wed, Sep 2 - Sun, Sep 6
United Airlines Logo
10:40 am - 5:44 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
8h 04m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
5:19 am - 1:20 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
7h 01m1 stop Houston George Bush Intcntl
$384United Airlines
Wed, Sep 2 - Sun, Sep 6
United Airlines Logo
10:40 am - 5:44 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
8h 04m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
5:19 am - 4:58 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
10h 39m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$389United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
11:59 am - 4:04 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
5h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
7:30 pm - 5:54 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
21h 24m1 stop Houston George Bush Intcntl
$543United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
11:59 am - 4:04 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
5h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 9:57 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
13h 57m1 stop Houston George Bush Intcntl
$543United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
11:59 am - 4:04 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
5h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 8:54 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
12h 54m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$548United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
11:59 am - 4:04 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
5h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 am - 4:59 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
10h 59m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$548United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
11:59 am - 4:04 pmTYS  Knoxville McGhee Tyson-MFE McAllen Miller Intl
5h 05m1 stop Houston George Bush Intcntl
United Airlines Logo
7:30 pm - 5:54 pmMFE  McAllen Miller Intl-TYS Knoxville McGhee Tyson
21h 24m1 stop Houston George Bush Intcntl
$593United Airlines
Booking Insights

Price, demand and travel trends for Knoxville to McAllen flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to McAllen with more confidence.

How much is a round-trip flight from Knoxville to McAllen?

Round-trip flights from Knoxville to McAllen start at $379. Prices are below average for this route right now, with typical round-trip fares ranging from $401 to $601. The lowest price found in the past 5 days was $379 on American Airlines.

Find deals

Key details for Knoxville to McAllen flights

Low season

March

Cheapest flight

$379
Flight from Knoxville to McAllen

When to book flights from Knoxville to McAllen

Are your dates flexible? Find out the best times to travel from Knoxville to McAllen based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to McAllen flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to McAllen?

    Flights from Knoxville to McAllen usually depart from Knoxville McGhee Tyson (TYS) and arrive at McAllen Miller Intl (MFE).

  • What cabin classes can I book on flights from Knoxville to McAllen?

    Only Economy Class is available on flights from Knoxville to McAllen.

  • Which airports do connecting flights from Knoxville to McAllen pass through?

    Connecting flights from Knoxville to McAllen most commonly pass through:

    • Dallas/Fort Worth (DFW) - 96% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 4% of one-stop connections
    Together, these airports account for 100% of one-stop bookings on this route.

  • Can I save money by using flexible dates for flights from Knoxville to McAllen?

    Yes. Being flexible with your travel dates can save you up to 49% on the Knoxville to McAllen route. Friday is the cheapest departure day at $401 round-trip on average, while Saturday is the most expensive at $782, a difference of $381. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Knoxville to McAllen?

    A nonstop flight from Knoxville to McAllen takes 0h 00m, covering 1,072 miles.

  • What are the earliest and latest flights from Knoxville to McAllen?

    These are the earliest and latest flight times available from Knoxville to McAllen:

    • Earliest: departs at 12:00 am and lands at 12:00 am
    • Latest: departs at 12:00 am and lands at 12:00 am.

    The flight takes about 0h 00m.

  • Do I need a passport to fly from Knoxville to McAllen?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to McAllen changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $1,666. That means the highest observed fare was about 4x higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Knoxville to McAllen?

    Flying via Houston George Bush Intcntl (IAH) gives the shortest average 1-stop total travel time at 5h 18m, compared with 5h 30m via Dallas/Fort Worth (DFW).

  • What is the time difference between Knoxville and McAllen?

    McAllen is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at McAllen Miller Intl Airport (MFE)?

    McAllen Miller Intl Airport (MFE) hosts 5 major car rental companies, with daily rates starting from around $24 for economy cars. Top options include:
    · Dollar
    · Thrifty
    · Budget
    · Hertz
    · Enterprise Rent-A-Car

  • How much should I expect to pay for a Knoxville to McAllen flight?

    Round-trip flights from Knoxville to McAllen range from $401 to $601, with an average of $485 over the past 12 months. Anything below $401 counts as a good deal.

Your guide to booking Knoxville to McAllen flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Friday departure instead of Saturday. On this route, Friday flights average $401 - about $381 less than Saturday (49% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to McAllen trip for June. Fares historically average $435 round-trip in that month - typically $347 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to McAllen Miller Intl Airport.
    - DoubleTree Suites by Hilton McAllen
    - Wyndham Garden McAllen at La Plaza Mall
    - OYO Hotel Mcallen Airport South

Everything you need to know for your flight from Knoxville to McAllen

Information on your arrival and departure airports

Knoxville (TYS)
McAllen (MFE)