MFE - TYS

$329 Find Cheap Flights from McAllen to Knoxville - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from McAllen to Knoxville departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$329
Typical prices: $439-$539
American Airlines
Tue 8/25Sun 8/30
MFE - TYS • 1 stop
Top airlines
American Airlines
Cheapest • from $329 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between McAllen and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 100% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from McAllen to Knoxville (MFE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from McAllen to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from McAllen to Knoxville

Tue, Aug 25 - Sun, Aug 30
American Airlines Logo
4:18 pm - 11:18 pm
MFE
-
TYS
6h 00m
1 stop
American Airlines Logo
6:03 am - 10:15 am
TYS
-
MFE
5h 12m
1 stop
$329American Airlines
Thu, Aug 27 - Thu, Sep 3
Delta Logo
12:37 pm - 11:52 pm
MFE
-
TYS
10h 15m
2 stops
Delta Logo
2:16 pm - 11:59 pm
TYS
-
MFE
10h 43m
2 stops
$359Delta
Fri, Aug 14 - Tue, Aug 18
American Airlines Logo
4:18 pm - 11:18 pm
MFE
-
TYS
6h 00m
1 stop
American Airlines Logo
6:03 am - 10:14 am
TYS
-
MFE
5h 11m
1 stop
$379American Airlines
Fri, Aug 14 - Tue, Aug 18
American Airlines Logo
5:45 am - 12:56 pm
MFE
-
TYS
6h 11m
1 stop
American Airlines Logo
12:09 pm - 7:09 pm
TYS
-
MFE
8h 00m
2 stops
$384American Airlines
Tue, Aug 25 - Sun, Aug 30
American Airlines Logo
11:04 am - 8:59 pm
MFE
-
TYS
8h 55m
2 stops
American Airlines Logo
6:03 am - 10:15 am
TYS
-
MFE
5h 12m
1 stop
$386American Airlines
Mon, Aug 10 - Fri, Aug 14
Allegiant Air Logo
10:19 am - 8:18 pm
MFE
-
TYS
8h 59m
1 stop
Allegiant Air Logo
9:08 pm - 10:29 am
TYS
-
MFE
14h 21m
1 stop
$399Allegiant Air
Thu, Aug 27 - Thu, Sep 3
American Airlines Logo
4:18 pm - 11:18 pm
MFE
-
TYS
6h 00m
1 stop
American Airlines Logo
6:03 am - 10:15 am
TYS
-
MFE
5h 12m
1 stop
$400American Airlines
Fri, Aug 14 - Tue, Aug 18
American Airlines Logo
1:49 pm - 10:58 pm
MFE
-
TYS
8h 09m
2 stops
American Airlines Logo
1:56 pm - 10:02 pm
TYS
-
MFE
9h 06m
2 stops
$434American Airlines
Thu, Aug 27 - Thu, Sep 3
Multiple Airlines Logo
9:21 pm - 9:46 pm
MFE
-
TYS
23h 25m
1 stop
Multiple Airlines Logo
2:34 pm - 8:34 pm
TYS
-
MFE
31h 00m
2 stops
$444Multiple Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
7:00 am - 1:20 pm
MFE
-
TYS
5h 20m
1 stop
United Airlines Logo
12:00 pm - 5:45 pm
TYS
-
MFE
6h 45m
1 stop
$505United Airlines
Booking Insights

KAYAK's insights & trends for McAllen to Knoxville flights

Get data-powered insights and trends into flights from McAllen to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from McAllen to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from McAllen to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from McAllen to Knoxville is February, where tickets cost $0 (return) on average. On the other hand, the most expensive months are January and November, where the average cost of round-trip tickets is $763 and $694 respectively.

Find deals

Good to know

Low season

March

Cheapest flight

$329
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from McAllen to Knoxville

When to book flights from McAllen to Knoxville

Are your dates flexible? Find out the best times to travel from McAllen to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from McAllen to Knoxville

  • What is the cheapest flight from McAllen to Knoxville?

    In the last 5 days, the lowest price for a flight from McAllen to Knoxville was $329 for a round-trip ticket.

  • Do I need a passport to fly between McAllen and Knoxville?

    No, a passport isn't needed to fly from McAllen to Knoxville. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from McAllen to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from McAllen to Knoxville?

    oneworld is the only airline alliance operating flights between McAllen and Knoxville.

  • How does KAYAK find such low prices on flights from McAllen to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from McAllen to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from McAllen to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from McAllen is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from McAllen to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to McAllen with another airline. Booking your flights between McAllen and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from McAllen to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from McAllen up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from McAllen to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from McAllen to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from McAllen to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11841 reviews
7.2Comfort
7.9Crew
6.8Entertainment
6.4Food
7.5Boarding
Airline reviews

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

6.0 GoodLisa, Jul 2026
DFW - TYS
Read more American Airlines reviews

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

technology worked well and everything ran smoothly. The seats are quite cramped so please don't try to re-engineer the cabin to squeeze more bodies on board.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

The pilot greased the landing and the crew was fantastic.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

At least it was a short flight. Greyhound with wings.

Our flight got changed and/or delayed 8 times before we boarded.

Everything you need to know for your flight from McAllen to Knoxville

Information on your arrival and departure airports

McAllen (MFE)
Knoxville (TYS)