MFE - TYS

$339 Find Cheap Flights from McAllen to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from McAllen to Knoxville departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from McAllen to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from McAllen to Knoxville, as well as popular online travel agencies
Travelers love KAYAK
41 299 237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$339
United Airlines
Sat 1/24Wed 1/28
MFE - TYS • 1 stop
Cheapest one-way
Multiple Airlines
Sun 12/14
MFE - TYS • multi-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from McAllen to Knoxville (MFE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from McAllen to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from McAllen to Knoxville

Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
5:25 pm - 11:44 pm
MFE
-
TYS
5h 19m1 stop
United Airlines Logo
11:40 am - 4:07 pm
TYS
-
MFE
5h 27m1 stop
$339United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
12:05 pm - 7:50 pm
MFE
-
TYS
6h 45m1 stop
United Airlines Logo
11:10 am - 8:02 pm
TYS
-
MFE
9h 52m2 stops
$344United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
7:00 am - 8:52 pm
MFE
-
TYS
12h 52m2 stops
United Airlines Logo
11:10 am - 8:02 pm
TYS
-
MFE
9h 52m2 stops
$349United Airlines
Thu, Apr 30 - Sun, May 3
American Airlines Logo
6:13 pm - 11:47 pm
MFE
-
TYS
4h 34m1 stop
American Airlines Logo
4:33 pm - 10:21 pm
TYS
-
MFE
6h 48m1 stop
$414American Airlines
Fri, Jan 16 - Mon, Jan 19
American Airlines Logo
7:28 am - 3:46 pm
MFE
-
TYS
7h 18m1 stop
American Airlines Logo
6:51 pm - 11:17 pm
TYS
-
MFE
5h 26m1 stop
$422American Airlines
Fri, Jan 16 - Mon, Jan 19
American Airlines Logo
12:20 pm - 9:44 pm
MFE
-
TYS
8h 24m2 stops
American Airlines Logo
6:51 pm - 11:17 pm
TYS
-
MFE
5h 26m1 stop
$427American Airlines
Fri, Jan 16 - Mon, Jan 19
American Airlines Logo
12:20 pm - 9:44 pm
MFE
-
TYS
8h 24m2 stops
American Airlines Logo
2:17 pm - 11:17 pm
TYS
-
MFE
10h 00m2 stops
$545American Airlines
Thu, Apr 30 - Sun, May 3
American Airlines Logo
6:13 pm - 11:47 pm
MFE
-
TYS
4h 34m1 stop
American Airlines Logo
4:03 pm - 11:59 pm
TYS
-
MFE
8h 56m2 stops
$564American Airlines
Thu, Apr 30 - Sun, May 3
Delta Logo
5:25 am - 6:15 pm
MFE
-
TYS
11h 50m2 stops
Delta Logo
5:30 am - 12:23 pm
TYS
-
MFE
7h 53m2 stops
$571Delta
Thu, Apr 30 - Sun, May 3
United Airlines Logo
6:55 pm - 8:45 pm
MFE
-
TYS
24h 50m2 stops
United Airlines Logo
4:25 pm - 10:59 pm
TYS
-
MFE
31h 34m3 stops
$847United Airlines
Booking Insights

KAYAK's insights & trends for McAllen to Knoxville flights

Get data-powered insights and trends into flights from McAllen to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from McAllen to Knoxville?

The average price of all round-trip flights from McAllen to Knoxville clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from McAllen to Knoxville, look for departures on Tuesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from Knoxville, Wednesday is the cheapest day to fly and Thursday is the most expensive.

Find deals

Good to know

Cheapest flight$339
Most popular time to fly and prices are also 16% lower on average.
Flight from McAllen to Knoxville

When to book flights from McAllen to Knoxville

Are your dates flexible? Find out the best times to travel from McAllen to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from McAllen to Knoxville

  • What is the cheapest flight from McAllen to Knoxville?

    In the last 3 days, the lowest price for a flight from McAllen to Knoxville was $339 for a round-trip ticket.

  • Do I need a passport to fly between McAllen and Knoxville?

    No, a passport isn't needed to fly from McAllen to Knoxville. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from McAllen to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from McAllen to Knoxville?

    oneworld is the only airline alliance operating flights between McAllen and Knoxville.

  • How does KAYAK find such low prices on flights from McAllen to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from McAllen to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from McAllen to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from McAllen is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from McAllen to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to McAllen with another airline. Booking your flights between McAllen and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from McAllen to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from McAllen up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from McAllen to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from McAllen to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from McAllen to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11054 reviews
6.5Food
6.9Entertainment
7.2Comfort
8.0Crew
7.5Boarding
Airline reviews

Attendants were pleasant and the flight was smooth and relaxed.

10.0 ExcellentDawn C, Dec 2025
DFW - MIA
Read more American Airlines reviews

Attendants were pleasant and the flight was smooth and relaxed.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

I have a gluten allergy so did have any food

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

The only thing to like was that we eventually got to our destination

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Everything you need to know for your flight from McAllen to Knoxville

Information on your arrival and departure airports

McAllen (MFE)
Knoxville (TYS)