$47 Find Cheap Flights from Knoxville to Mississippi - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Mississippi departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Knoxville to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$272
Gulfport
Gulfport1 stop$299
Memphis
Memphisnonstop$84
Jackson
Jackson1 stop$272
Gulfport
Gulfport1 stop$299
Memphis
Memphisnonstop$84

Book Cheap Knoxville to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Mississippi

Fri, Oct 16 - Sun, Oct 18
Allegiant Air Logo
7:45 pm - 8:04 pm
TYS
-
MEM
1h 19mnonstop
Allegiant Air Logo
3:21 pm - 5:33 pm
MEM
-
TYS
1h 12mnonstop
$84Allegiant Air
Fri, Nov 6 - Sun, Nov 8
Allegiant Air Logo
6:47 pm - 7:06 pm
TYS
-
MEM
1h 19mnonstop
Allegiant Air Logo
6:46 pm - 8:58 pm
MEM
-
TYS
1h 12mnonstop
$90Allegiant Air
Fri, Nov 6 - Sun, Nov 8
Multiple Airlines Logo
8:35 am - 7:18 pm
TYS
-
MEM
11h 43m
1 stop
Multiple Airlines Logo
6:46 pm - 8:58 pm
MEM
-
TYS
1h 12mnonstop
$171Multiple Airlines
Thu, Sep 24 - Sun, Sep 27
Multiple Airlines Logo
5:17 pm - 7:18 pm
TYS
-
MEM
27h 01m
2 stops
Multiple Airlines Logo
6:47 pm - 8:59 pm
MEM
-
TYS
1h 12mnonstop
$201Multiple Airlines
Sat, Sep 12 - Sat, Sep 19
American Airlines Logo
6:06 pm - 10:52 pm
TYS
-
JAN
5h 46m
1 stop
American Airlines Logo
3:27 pm - 9:06 pm
JAN
-
TYS
4h 39m
1 stop
$272American Airlines
Mon, Aug 31 - Wed, Sep 2
Delta Logo
4:38 pm - 6:51 pm
TYS
-
JAN
3h 13m
1 stop
Delta Logo
5:01 pm - 11:52 pm
JAN
-
TYS
5h 51m
1 stop
$273Delta
Tue, Aug 25 - Tue, Sep 1
Delta Logo
6:12 pm - 11:11 pm
TYS
-
JAN
5h 59m
1 stop
Delta Logo
5:32 am - 11:11 am
JAN
-
TYS
4h 39m
1 stop
$273Delta
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
2:21 pm - 8:05 pm
TYS
-
JAN
6h 44m
1 stop
United Airlines Logo
2:05 pm - 9:45 pm
JAN
-
TYS
6h 40m
1 stop
$273United Airlines
Sat, Aug 22 - Sat, Aug 29
United Airlines Logo
6:02 pm - 11:18 pm
TYS
-
MEM
6h 16m
1 stop
United Airlines Logo
2:37 pm - 8:53 pm
MEM
-
TYS
5h 16m
1 stop
$275United Airlines
Fri, Aug 28 - Sat, Aug 29
American Airlines Logo
6:05 pm - 10:30 pm
TYS
-
GPT
5h 25m
1 stop
American Airlines Logo
1:50 pm - 7:00 pm
GPT
-
TYS
4h 10m
1 stop
$333American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Mississippi flights

Get data-powered insights and trends into flights from Knoxville to Mississippi to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to Mississippi?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Mississippi, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Mississippi is January, when tickets cost $319 (return) on average. On the other hand, the most expensive months are September and March, when the average cost of round-trip tickets is $813 and $734 respectively.

Good to know

Low season

January

Cheapest flight

$47
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly and prices are also 32% lower on average.
Flight from Knoxville to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Knoxville to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8487 reviews
7.8Entertainment
8.1Boarding
7.8Comfort
7.2Food
8.5Crew
Airline reviews

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

4.0 OkayErnest, Jul 2026
TYS - ATL
Read more Delta reviews

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

The CRJ-900 was clean but the overhead air vents were broken in our First Class row, making the cabin very hot until about 30 mins into the flight. The flight attendants were both extremely apologetic and accommodating though so that is why I rated the flight as very good. They checked on us many times and truly showed they cared. The snacks for an hour and a half flight could be better. Would be nice if there was a small plated meal over convenient store snacks. WiFi also was not working. And it would be nice if Delta had adjustable headrests on these planes.

I was in Comfort and we didn’t get any drinks, chips or anything! First Class got full service on the flight and Comfort got nothing. Seat was horrible and uncomfortable

Short trip, no food and therefore no expectation for much interaction with staff who were pleasant and professional. My critique is on comfort of the seats. Exit rows and comfort seats do not provide enough personal space for 3 side-by-side seats, especially when in the middle row. Some passengers are not considerate of the middle seat and there should be signs that state something to the effect of: "please consider giving middle seats use of the armrests."

The tray table was broken and the food was terrible.

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

Not one thing to like. Three flights all with “mechanical” delays. Never got to where I was going and spent additional $500 for a hotel room. American Airlines is the worst in the industry!

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

I didn’t like anything, being platinum pro get you absolutely nowhere and does not increase the customer service treatment whatsoever anymore. My flight was canceled and they put me on a flight eight hours later that would’ve got me back in the middle of the night. They could’ve easily move me up to an hour Prior on an earlier flight. My second flight was unreasonable to take, the third flight was also canceled due to mechanical issues like the first flight. I don’t know what’s going on with American, but they are falling apart, after seven flight changes I finally got home, Unreasonable.

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

This was a horrible American Airlines experience, and it discourages me from flying with them again. It may have stemmed from a mechanical delay, but it appeared that the team was unprepared to respond to the delay. After boarding, we waited an hour before finally taking off. After landing at our destination, we waited an additional hour on the tarmac waiting for a gate (at 8:00pm) to be assigned and cleared. The flight crew did their best, but they were clearly tired and also ready to be done for the day. Because of the delay, I missed a connecting flight. It was a very poor experience.

Fantastic! If it had not been for a check-in agent in Knoxville I may have not gotten my passes on British Airways. I couldn’t check-in online because British Airways had messed us the info on my tickets to London & Inverness. AA’s was great! British Airways was a continuous series of delays and frustrations.

The flight was short. However, my bag was delayed and was put on another flight.

Wheelchair was waiting for me,changed to a better seat which was great as it's hard for me to walk

Everything you need to know for your flight from Knoxville to Mississippi

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