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Find cheap flights from Knoxville to Missouri from $55

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Missouri departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Mon 5/20
Mon 5/27

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Best Missouri Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Kansas City
Kansas City1 stop$220
St. Louis
St. Louis1 stop$226
Springfield
Springfield1 stop$228

Good to know

Low season

January

High season

September

Cheapest flight

$55
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Knoxville to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Knoxville to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missouri from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missouri with an airline and back to Knoxville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missouri from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Missouri

  • Morning departure is around 7% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 4 airlines serving from Knoxville to Missouri

 
Need help choosing which airline to fly with from Knoxville to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 11094 reviews
7.9comfort
8.2boarding
8.6crew
8.0entertainment
7.5food
Airline reviews

Seat back monitors and outlets were dead and not working.

8.0 ExcellentCarl, Apr 2024JFK - FLL
Read more about Delta reviews

Seat back monitors and outlets were dead and not working.

Everything was great except for the seat. The backrest would not stay in the upright position.

I usually have a positive experience with Delta. Complimentary upgrades are always nice!

Flight delayed about 2 hrs so it made it a VERY late night

It was a crowded flight. They did the best they could.

Service was good for such a short flight. Small plane but smooth flight.

Worst flight in my life. Only was scheduled for a 45 min flight to get our connection flight. It was late by 40 minutes and we missed our connection. Delta was totally useless trying to help and unable to get my family on the next flight because they overbooked it Thus had to get a hotel at my expense and lost a day at Disney as a result. Cost me about a $1000 if you add 2 hotels meals shuttles etc to get thru the day Awful customer service by Delta in Detroit totally useless people

The experience was good and the flight departed on time and landed early

The flight was delayed but we got to our final destination.

Boarding was great. The flight landed early. It took the crew over an hour and a half to bring out drinks. I paid to upgrade my seat to Comfort+ only to be near a crying/screaming baby who was seldom quiet. Noise-cancelling earbuds didn’t even help. Waste of money to upgrade.

More facilities to transport to the gates......felt too much walking distance

Just happy I flew Qatar Airways awesome no wonder they are #1 in the world right now! The food was just delicious, very courteous, professional crew.

It was good no problems made it on time for the next flight overseas!

It was a really long flight from Doha to Philadelphia and it was overall a good one. The one area that I would comment on is that there is a lot of single-use plastic and disposables in the meal service for American Airlines. It would be great to see more circular options in the meal service to reduce the amount of waste.

Suddenly Flight has been change by Qatar and there’s no information is there of us from Bom to Doha and counter person is behaving like Qatar owner next I will not buy Qatar and I will not suggest anyone to fly in Qatar

The crew was fantastic and the over flight was perfect as well.

They shld provide food. Between food they are giving 10 hours gap which is toooo much

The crew was great and the food and liquor offerings were good. Seats were a bit cramped. Flight arrived early at destination. That's a plus.

All over with Qatar airlines my experience was really bad due to delays and then putting me on different airlines and after 8 hours of wait I had to listen to their is no plane to fly for another 24 hours. Wore experience ever.

I had already opted for Vegan food before 2 months yet they say we have no record for it,

I just wrote a text which was supposed to be for the flight from Denver to spokane not Frankfurt to Denver.

On time every leg of the journey and exceptional staff at counter, gate, and on board. I haven’t travelled in US for a long time and was genuinely surprised how pleasant this was.

The delays (5 hrs) were a comedy of errors, and the multiple safety issues encountered were very concerning.

flight delays, staff only communicating when pushed, food service lasting a grand total of 7 minutes, stuck in seat from 45mins into flight until landing

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

they made me check my carryon. There was space in the overhead bins.

Nice flight, nice crew but no cookie or napkin with my seltzer.

Trip was smooth bumpy from the wind but no issues at all the crew attendant was very pleasant and had great customer service

This was a Lufthansa flight. Disappointing main meal. Very rough over Canada and arrival at FRA. IFE was almost unusable.

It got me where I needed it to; not much more. It had no competition so that was why I chose it.

Comfort of seats, ease of boarding. Food selection could be better

i suspect i caught flu on this flight as i could hear someone coughing a few rows back and ended up with flu a few days later. also tiresome to have to watch movies on my device by holding up smartphone screen, would have liked to have in seat display.

Flight was fine. It took an unusually long time to have baggage delivered to the carousel in ORD.

No problems with flight. Even though I had a short layover in DFW, I was still able to easily make my connection.

American Airlines continues to price it can provide the least comfortable passenger experience in the air. This legacy carrier rivals the budgets for both terrible seats and inadequate amenities. I am a 5’7” woman who is not wider than a coach seat (even on these narrow bodied aircraft). My 3.5 hour flight was terribly uncomfortable because the leg room is inadequate (my knees hit the seat on front of me even when it was not reclined); the seat barely reclines; and the foam padding is worn thin to the extent one can feel the metal supports of the seat. Add to this the fact that the aisle is super narrow, so that the drink cart literally scrapes the arm rest of the aisle seat. It’s basically torture.

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Plane took off without me, my stepdad and a dozen other passengers. It went from an hour delay to boarding in 15 montures without notifying anyone. Names were not called overhead. Now I’m missing a day of work and stuck in Charolette overnight paying for a hotel and Ubers out of pocket

I arrived to the airport 2 hours before my American Airlines flight was scheduled to take off. I have TSA pre-check. The airport was crazy packed when I arrived. After momentarily standing in the pre-check line, the TSA agent said that I am not pre-check. Of course I said that I am because I entered my KTN number on all my traveling sites and programs. I had to get out of line and go back to the AA counter to discover that American Airlines did not add my KTN to my boarding pass. I had to call TSA to find out my number, then have AA enter it onto my boarding pass. The emblem would not load onto my boarding pass. By this time, I decided to use my Clear in order to get through TSA but the line was ridiculous long. By the time I made through TSA, I missed my 11:08am flight and was re-booked for the 5:30pm. This is after the AA employee told me I should have gotten to the airport early. AA use to be a dependable airline not I use them only if I have too.

Average - flew with Jet Blue internal and it was far more comfortable and better food and entertainment. Notable difference

Flight from SBP to DFW 1. They rerouted us through PHX 2. Delayed flight out of SBP for 3 hrs so we missed our connection Downgrade on rerouted flight. Back of the plane, center seats, didn't sit together 4. Return flight out of DFW same exact thing. Delayed, missed connection, Downgrade + they lost our luggage! A complete mess.

Book cheap flights from Knoxville to Missouri

Recent round-trip flight deals

7/12Fri
1 stopAmerican Airlines
5h 55mTYS-MCI
7/16Tue
1 stopAmerican Airlines
4h 31mMCI-TYS
$220
6/1Sat
1 stopAmerican Airlines
5h 34mTYS-STL
6/3Mon
1 stopAmerican Airlines
4h 12mSTL-TYS
$226
8/31Sat
1 stopDelta
4h 33mTYS-SGF
9/4Wed
1 stopDelta
4h 08mSGF-TYS
$228
5/11Sat
1 stopDelta
7h 07mTYS-MCI
5/14Tue
1 stopDelta
6h 04mMCI-TYS
$228
5/24Fri
1 stopFrontier
13h 42mTYS-STL
5/27Mon
1 stopFrontier
9h 37mSTL-TYS
$302
5/28Tue
1 stop
12h 35mTYS-MCI
6/4Tue
2 stops
24h 04mMCI-TYS
$310
7/12Fri
1 stop
5h 14mTYS-MCI
7/16Tue
2 stops
24h 27mMCI-TYS
$337
7/28Sun
1 stopFrontier
23h 02mTYS-STL
8/2Fri
1 stopFrontier
19h 50mSTL-TYS
$341
7/12Fri
1 stopUnited Airlines
5h 06mTYS-MCI
7/16Tue
2 stopsUnited Airlines
14h 51mMCI-TYS
$545
8/31Sat
1 stopUnited Airlines
4h 44mTYS-SGF
9/4Wed
2 stopsUnited Airlines
8h 05mSGF-TYS
$581

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Recent one-way flight deals

5/16Thu
1 stopFrontier
10h 13mTYS-STL
$55
5/4Sat
1 stopFrontier
28h 31mTYS-STL
$59
5/17Fri
1 stopFrontier
13h 23mTYS-STL
$65
7/3Wed
1 stopAmerican Airlines
4h 17mTYS-MCI
$97
5/18Sat
1 stop
7h 34mTYS-MCI
$138
6/8Sat
1 stopDelta
6h 36mTYS-MCI
$219
5/17Fri
2 stops
27h 58mTYS-STL
$224
6/8Sat
1 stopAmerican Airlines
5h 27mTYS-MCI
$248
5/2Thu
1 stopDelta
4h 12mTYS-SGF
$294
5/4Sat
2 stopsUnited Airlines
24h 23mTYS-STL
$294

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Last minute flights from Knoxville to Missouri

Last minute flight, train and bus deals

4/25Thu
multi-stopAmerican Airlines
5h 54mTYS-STL
4/27Sat
multi-stopAmerican Airlines
4h 29mSTL-TYS
$243
4/25Thu
multi-stopAmerican Airlines
5h 54mTYS-STL
4/28Sun
multi-stopAmerican Airlines
4h 29mSTL-TYS
$252
4/24Wed
multi-stopAmerican Airlines
6h 33mTYS-SGF
4/28Sun
multi-stopAmerican Airlines
7h 25mSGF-TYS
$323
4/25Thu
multi-stop
8h 34mTYS-STL
4/27Sat
multi-stop
26h 26mSTL-TYS
$509
4/25Thu
multi-stop
13h 40mTYS-STL
4/27Sat
multi-stop
26h 26mSTL-TYS
$510
4/25Thu
multi-stopAmerican Airlines
4h 21mTYS-STL
4/27Sat
multi-stopAmerican Airlines
11h 12mSTL-TYS
$520
4/24Wed
multi-stopAmerican Airlines
10h 14mTYS-SGF
4/28Sun
multi-stopAmerican Airlines
5h 33mSGF-TYS
$591
4/24Wed
multi-stopAmerican Airlines
9h 28mTYS-SGF
4/28Sun
multi-stopAmerican Airlines
10h 21mSGF-TYS
$596
4/24Wed
multi-stopAmerican Airlines
4h 21mTYS-STL
4/24Wed
multi-stopAmerican Airlines
7h 37mSTL-TYS
$844
4/24Wed
multi-stopAmerican Airlines
7h 12mTYS-STL
4/24Wed
multi-stopAmerican Airlines
7h 33mSTL-TYS
$849

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Knoxville - Missouri Flights

Departure:

Knoxville (TYS)United States

Return flight deals:

Missouri - Knoxville

Cabin classes: