Which cabin classes are available on flights from Knoxville to Panama?

On flights from Knoxville to Panama you can book Economy Class or First Class.

What are some popular landmarks in Panama?

KAYAK travelers' favorite landmarks in Panama include: • ATLAPA Conventions Center • Panama Old Cathedral • Veneto Casino • Ancon Hill

Is now a good time to book a flight from Knoxville to Panama?

Fares from Knoxville to Panama are around their usual level right now. A round-trip under $556 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

What airlines fly nonstop from Knoxville to Panama?

Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Knoxville to Panama. One-stop options include American Airlines and Delta.

How much should I budget for a flight from Knoxville to Panama?

Over the past 12 months, round-trip fares from Knoxville to Panama have ranged from $556 to $766.

What are the cheapest airlines to fly with from Knoxville to Panama?

Looking at KAYAK data from the last 12 months, the cheapest airlines to fly with from Knoxville to Panama are: • United Airlines (avg. price $529) • American Airlines (avg. price $624) • Delta (avg. price $653) • Copa Airlines (avg. price $740) • GOL (avg. price $766)

What's the most popular airline to fly with from Knoxville to Panama?

Drawing on KAYAK data from the past three months, the most popular airlines to fly with from Knoxville to Panama are: • United Airlines • Delta • GOL

What are the most popular regions in Panama?

Papenburg is the most popular region with KAYAK travelers, making up 100% of all interest in visiting Panama, based on the past three months of KAYAK data.

What are the most popular flight destinations in Panama?

Panama City is the most popular flight destination in Panama, based on KAYAK data from the past 3 months.

How many one-stop flights are there from Knoxville to Panama across the week?

There are typically 2 one-stop flights a day from Knoxville to Panama (14 a week), with the most operating on Monday.

$444 CHEAP FLIGHTS from Knoxville to Panama

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Discover the best prices for you by selecting your travel dates on KAYAK.

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Recent round-trip flight deals from Knoxville to Panama

Thu, Dec 31 - Wed, Jan 20

11:43 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 55m1 stop Houston George Bush Intcntl

4:41 pm - 11:12 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

18h 31m1 stop Houston George Bush Intcntl

$681United Airlines

Thu, Dec 31 - Thu, Jan 21

11:43 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 55m1 stop Houston George Bush Intcntl

8:55 am - 9:59 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

13h 04m1 stop Houston George Bush Intcntl

$681United Airlines

Thu, Dec 31 - Tue, Jan 19

6:57 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

12h 41m1 stop Houston George Bush Intcntl

4:41 pm - 11:12 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

18h 31m1 stop Houston George Bush Intcntl

$681United Airlines

Tue, Jan 19 - Mon, Jan 25

6:55 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

12h 43m1 stop Houston George Bush Intcntl

10:00 am - 7:51 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

9h 51m1 stop Newark

$681United Airlines

Wed, Feb 24 - Mon, Mar 1

6:10 am - 8:02 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 52m1 stop Newark

10:00 am - 8:22 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

10h 22m1 stop Newark

$681United Airlines

Wed, Feb 24 - Mon, Mar 1

6:30 am - 5:12 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

10h 42m1 stop Houston George Bush Intcntl

10:00 am - 8:22 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

10h 22m1 stop Newark

$681United Airlines

Wed, Dec 30 - Thu, Jan 21

5:30 am - 5:10 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

23h 40m2 stops Washington, D.C. Dulles Intl Newark

8:55 am - 9:59 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

13h 04m1 stop Houston George Bush Intcntl

$686United Airlines

Thu, Dec 31 - Thu, Jan 21

1:30 pm - 5:10 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

15h 40m2 stops Washington, D.C. Dulles Intl Newark

8:55 am - 11:59 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

15h 04m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$686United Airlines

Tue, Jan 19 - Mon, Jan 25

6:01 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 37m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

4:41 pm - 2:47 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

22h 06m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$686United Airlines

Sun, Feb 14 - Wed, Feb 17

7:35 pm - 5:12 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

21h 37m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

11:35 am - 9:53 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

10h 18m1 stop Houston George Bush Intcntl

$686United Airlines

Booking Insights

Price, demand and travel trends for Knoxville to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

What are the cheapest fares from Knoxville to Panama right now?

The cheapest fare from Knoxville to Panama in the last week was $681 round-trip, to Panama City Tocumen Intl (PTY).

Which airport in Panama is the cheapest to fly to from Knoxville?

All flights from Knoxville to Panama arrive at Panama City Tocumen Intl (PTY). On average, round-trip fares are around $653.

What’s the cheapest day to fly from Knoxville to Panama?

Saturday tends to be the cheapest day to fly from Knoxville to Panama, while Friday is the most expensive. Fares run about 29% higher that day, based on the past 12 months of KAYAK data.

Find deals

Low season	July
High season	January
Cheapest flight	$444

Beat the crowds with an average 54% drop in travelers.

The most popular month to fly with an average 53% increase in travelers.

One-way flight from Knoxville to Panama City

Is now a good time to book a flight from Knoxville to Panama?
Fares from Knoxville to Panama are around their usual level right now. A round-trip under $556 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.
How much should I budget for a flight from Knoxville to Panama?
Over the past 12 months, round-trip fares from Knoxville to Panama have ranged from $556 to $766.
What airlines fly nonstop from Knoxville to Panama?
Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Knoxville to Panama. One-stop options include American Airlines and Delta.
Which cabin classes are available on flights from Knoxville to Panama?
On flights from Knoxville to Panama you can book Economy Class or First Class.
What are some popular landmarks in Panama?
KAYAK travelers' favorite landmarks in Panama include:

• ATLAPA Conventions Center
• Panama Old Cathedral
• Veneto Casino
• Ancon Hill

If your travel dates are flexible, book your trip for April when flights are typically cheapest and avoid March when prices are at their highest.
Flying on Saturday is usually the cheapest. Flights on Friday cost about 29% more on average, so being flexible with your travel dates could help you save.
Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

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$444 Find Cheap Flights from Knoxville to Panama - Compare and Save

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Recent round-trip flight deals from Knoxville to Panama

Recent one-way flight deals from Knoxville to Panama

Price, demand and travel trends for Knoxville to Panama flights

What are the cheapest fares from Knoxville to Panama right now?

Which airport in Panama is the cheapest to fly to from Knoxville?

What’s the cheapest day to fly from Knoxville to Panama?

What are the cheapest airlines to fly with from Knoxville to Panama?

What's the most popular airline to fly with from Knoxville to Panama?

What are the most popular regions in Panama?

How many one-stop flights are there from Knoxville to Panama across the week?

What are the most popular flight destinations in Panama?

Key details for Knoxville to Panama flights

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Your Knoxville to Panama flight questions, answered

Your guide to booking Knoxville to Panama flights

More options for your flight from Knoxville to Panama

Complete your trip to Panama with a hotel stay or car rental

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Flights from other airports in Knoxville to Panama

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Flights from Knoxville to popular cities in Panama