TYS - PTY

$205 Find Cheap Flights from Knoxville to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Panama City departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$460
Typical prices: $552-$636
American Airlines
Fri 4/24Fri 5/1
TYS - PTY • 2 stops
Cheapest one-way
$205
United Airlines
Mon 1/26
TYS - PTY • 1 stop
Top airlines
American Airlines
Cheapest • from $460 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 24% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Panama City (TYS-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Panama City

Fri, Apr 24 - Fri, May 1
American Airlines Logo
6:28 pm - 12:15 pm
TYS
-
PTY
18h 47m2 stops
American Airlines Logo
1:55 pm - 11:14 pm
PTY
-
TYS
8h 19m1 stop
$460American Airlines
Fri, Feb 27 - Tue, Mar 3
United Airlines Logo
7:05 am - 5:07 pm
TYS
-
PTY
10h 02m1 stop
United Airlines Logo
4:41 pm - 7:55 pm
PTY
-
TYS
27h 14m1 stop
$464United Airlines
Wed, Feb 11 - Wed, Feb 18
American Airlines Logo
5:36 pm - 3:15 pm
TYS
-
PTY
21h 39m1 stop
American Airlines Logo
2:40 pm - 11:11 am
PTY
-
TYS
20h 31m2 stops
$470American Airlines
Fri, Feb 27 - Tue, Mar 3
United Airlines Logo
11:41 am - 7:38 pm
TYS
-
PTY
7h 57m1 stop
United Airlines Logo
8:55 am - 7:55 pm
PTY
-
TYS
11h 00m1 stop
$476United Airlines
Wed, Feb 11 - Wed, Feb 18
American Airlines Logo
6:51 pm - 3:15 pm
TYS
-
PTY
20h 24m2 stops
American Airlines Logo
2:40 pm - 11:31 am
PTY
-
TYS
20h 51m2 stops
$480American Airlines
Fri, Feb 27 - Tue, Mar 3
United Airlines Logo
11:41 am - 7:38 pm
TYS
-
PTY
7h 57m1 stop
United Airlines Logo
4:41 pm - 7:55 pm
PTY
-
TYS
27h 14m1 stop
$484United Airlines
Fri, Apr 24 - Fri, May 1
United Airlines Logo
5:15 pm - 4:12 pm
TYS
-
PTY
23h 57m1 stop
United Airlines Logo
7:55 am - 7:55 pm
PTY
-
TYS
11h 00m1 stop
$505United Airlines
Wed, Feb 11 - Wed, Feb 18
United Airlines Logo
6:59 am - 5:07 pm
TYS
-
PTY
10h 08m1 stop
United Airlines Logo
4:41 pm - 7:55 pm
PTY
-
TYS
27h 14m1 stop
$521United Airlines
Fri, Feb 27 - Tue, Mar 3
WestJet Logo
5:35 am - 9:20 am
TYS
-
PTY
27h 45m2 stops
WestJet Logo
10:20 am - 5:56 pm
PTY
-
TYS
31h 36m2 stops
$5,167WestJet
Fri, Feb 27 - Tue, Mar 3
WestJet Logo
5:35 am - 9:20 am
TYS
-
PTY
27h 45m2 stops
WestJet Logo
10:20 am - 5:56 pm
PTY
-
TYS
31h 36m2 stops
$5,177WestJet
Booking Insights

KAYAK's insights & trends for Knoxville to Panama City flights

Get data-powered insights and trends into flights from Knoxville to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Panama City departing in April.

What is the cheapest month to fly from Knoxville to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Panama City is September, where tickets cost $471 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $754 and $707 respectively.

Good to know

Low seasonJuly
Cheapest flight$205
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 14% increase in price.
Flight from Knoxville to Panama City

When to book flights from Knoxville to Panama City

Are your dates flexible? Find out the best times to travel from Knoxville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Panama City

  • What is the cheapest flight from Knoxville to Panama City?

    In the last 3 days, the lowest price for a flight from Knoxville to Panama City was $205 for a one-way ticket and $460 for a round-trip.

  • Do I need a passport to fly between Knoxville and Panama City?

    Yes, you’ll need a passport to travel to Panama City from Knoxville.

  • Which aircraft models fly most regularly from Knoxville to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Panama City?

    oneworld, and Star Alliance are the airline alliances operating flights between Knoxville and Panama City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Panama City, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Panama City are United Airlines and American Airlines. With an average price for the route of $513 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $617 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9120 reviews
8.1Crew
7.7Boarding
7.1Entertainment
6.6Food
7.3Comfort
Airline reviews

I understand weather is an issue, but making us chase our plane down at five scheduled gates across three terminals in an airport the size of O'Hare was unfair. They'd have probably been better off to leave gates as TBD until the inbound plane is in final approach instead of running us all over the place. Also, props to the consistently-unprepared ground crew in Richmond for once again leaving my lane parked short of the gate because they couldn't have a crew in place on time with 2 hours notice...

6.0 GoodRob, Dec 2025
ORD - RIC
Read more United Airlines reviews

I understand weather is an issue, but making us chase our plane down at five scheduled gates across three terminals in an airport the size of O'Hare was unfair. They'd have probably been better off to leave gates as TBD until the inbound plane is in final approach instead of running us all over the place. Also, props to the consistently-unprepared ground crew in Richmond for once again leaving my lane parked short of the gate because they couldn't have a crew in place on time with 2 hours notice...

I boarded flight UA#1318 at Sacramento International Airport going back to Houston TX. The flight was scheduled at 5:10am. I was able to check in virtually using the United Airlines app. When I entered the airport, there was no one outside assisting with checked bags as it was for Delta Airlines. Immediately upon entering, there was a LONG, EXTREMELY LONG line to the kiosks to get boarding passes. I stand in line to get boarding passes then had to move to ANOTHER EXTREMELY LONG line to get my bags checked in. While standing in this line, we noticed an agent taking customers to 3 at a time to her station to check their bags in. Lucky for me, she called me back, checked my bags for me and I was on my way. I then encountered another long line at the TSA check and to avoid I ending up having to sign up for CLEAR to bypass it. So glad, I did.,...Both of my flights were great with no issues, butthe check in progress at Bush Airport was so much smoother. Check-in at SMF airport needs to be anaylzed and corrected. Do better United, I know you can....thanks

cabin crew was OK, food was OK, the trip from the US to Munich was actually pretty bad comfort wise. Noisy aircraft, lights never dimmed even in Business class (night flight) barely sufficient amenities for the price. I have millions of miles with United but TBH American is gaining ground and Delta has always been marginally better then United although on paper United has more longes and cheaper upgrades.

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

Essy to get on. The hostess gave very little pop, the plane was late getting in, and we are still waiting for our bags. This sucks. :/

Sat next to a one year old. She crawled all over the place and made me laugh.

Not United Airlines' fault. It's ORL airport's fault.

Great flight. On time boarding. Smooth flight and on time arrival at EWR. The flight crew was marvelous and there was a great selection of movies on the entertainment system. Our bags were at the carousel before we got there. Another excellent flight from United.

United airlines has the best customer experience from booking to arrival. I always fly United airlines. The mileage program is excellent

They did the one thing that really matters - got to Chicago early.

Better service. No food options, but we did get drinks and a cookie.

Boarding was organized and timely. Food was mediocre, especially for first class travel.

We were 4+ hours delayed. AA is absolutely obnoxious. They just kept pushing back the time to the point where we did not get into Vegas until after midnight when we were supposed to arrive like 845pm.

My last flight on 25 Dec, it’s Christmas Day, everyone happy and very good mood. I really enjoy traveling with Americans Airlines from Miami to Minneapolis my home town after long flight from lhe to Doha then Miami. Thank you again to make my travels comfortable and relaxed. Best regards

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

I requested a low sodium meal. Reason being, I take medicine for high blood pressure and I wear compression socks on long flights to help with leg swelling. Having less sodium in meals really helps me feel better on long flights. I received my initial low sodium meal after takeoff. Just before landing, the crew came through with the meal cart and offered me what was being served. I said no thank you and then noticed my low sodium meal in the meal cart, with my name and seat assignment on it. I motioned to the crew member, but he grabbed the meal cart and proceeded to move to the rear of the aircraft. He didn’t see me or other passengers who had attempted to get this attention. He was more concerned about completing meal service since we were due to land in under 45 minutes. I pressed the call light five times from my seat to receive help, but no crew member responded to me. So, I didn’t receive a second meal, one that I requested (the low sodium option). This led me to have a migraine from only eating one meal on an 11-hour flight. This is why I’m not a fan of flying US-based airlines overseas. The crew members continue to show the absolute worst customer service experience. I would not recommend flying American for overseas flights.

WiFi didn’t work the entire flight. Very disappointing. Minimal food and options - sadly the state of current affairs. All other aspects of the flight were fine.

Great flight - friendly and attentive team! Seats in coach were comfy, but a little cramped - but that is the case with all airlines ;)

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

I don’t know who decides what food to serve on these flights but I would be so embarrassed if I served this to anyone and call it food…

Everything you need to know for your flight from Knoxville to Panama City

Information on your arrival and departure airports