TYS - PTY
$395 Find Cheap Flights from Knoxville to Panama City - Compare and Save
This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Panama City departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
Everything you should know
Cheapest round-trip
$703
Typical prices: $586-$822
American Airlines
Tue 11/27Mon 12/3
TYS - PTY • 1 stop
Cheapest one-way
$395
Typical prices: $315-$410
Avianca
Sun 11/4
TYS - PTY • 2 stops
Cheap Flights from Knoxville to Panama City (TYS-PTY)
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Cheap flights from Knoxville to Panama City with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.
Fri, Nov 27 - Thu, Dec 3
6:00 am - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
8h 34m1 stop Miami
3:13 pm - 11:02 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
19h 49m2 stops Miami Chicago O'Hare Intl
$703American Airlines
Fri, Nov 27 - Thu, Dec 3
6:00 am - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
8h 34m1 stop Miami
3:13 pm - 12:05 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
8h 52m1 stop Miami
$703American Airlines
Fri, Nov 27 - Thu, Dec 3
8:50 pm - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
17h 44m2 stops Chicago O'Hare Intl Miami
3:13 pm - 10:32 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
19h 19m2 stops Miami Charlotte Douglas
$747American Airlines
Wed, Oct 28 - Sun, Nov 1
11:19 am - 7:02 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
8h 43m1 stop Newark
4:41 pm - 11:12 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
18h 31m1 stop Houston George Bush Intcntl
$798United Airlines
Wed, Oct 28 - Sun, Nov 1
5:40 pm - 1:45 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
21h 05m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
4:41 pm - 1:13 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
20h 32m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$803United Airlines
Wed, Oct 28 - Sun, Nov 1
11:59 am - 6:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
7h 39m1 stop Houston George Bush Intcntl
4:41 pm - 9:53 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson
17h 12m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$803United Airlines
Wed, Nov 4
9:45 am - 2:10 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
16h 25m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl
$395Avianca
Thu, Nov 19
9:45 am - 2:10 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
16h 25m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl
$395Avianca
Wed, Oct 28
4:14 pm - 8:13 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
28h 59m2 stops Fort Lauderdale San Juan Luis Munoz Marin Intl
$415Multiple Airlines
Wed, Nov 4
10:55 am - 8:19 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
9h 24m1 stop Fort Lauderdale
$426Multiple Airlines
Thu, Nov 19
11:36 am - 8:19 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
8h 43m1 stop Fort Lauderdale
$439Multiple Airlines
Wed, Oct 28
4:14 pm - 8:19 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
29h 05m1 stop Fort Lauderdale
$444Multiple Airlines
Wed, Nov 4
8:01 pm - 8:19 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
24h 18m3 stops Tampa St. Petersburg Chattanooga Lovell Field Fort Lauderdale
$560Multiple Airlines
Thu, Nov 19
3:42 pm - 7:45 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
28h 03m3 stops Washington, D.C. Dulles Intl Atlanta Hartsfield-Jackson Miami
$663Multiple Airlines
Wed, Oct 28
4:29 pm - 8:19 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl
28h 50m3 stops Tampa St. Petersburg Asheville Regional Fort Lauderdale
$678Multiple Airlines
Price, demand and travel trends for Knoxville to Panama City flights
Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.
Prices
Airlines
Layovers
How much is a round-trip flight from Knoxville to Panama City?
This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Panama City departing in november.
Round-trip flights from Knoxville to Panama City typically range from $586 to $822. The lowest price found in the past 5 days was $703, on American Airlines.
What’s the most popular layover airport when flying from Knoxville to Panama City?
KAYAK data for 1-stop round-trips over the past 3 months. Only counts itineraries with the same layover on both legs.Atlanta Hartsfield-Jackson (ATL) is the most popular layover for the Knoxville to Panama City route. 39% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ATL.
What is the cheapest layover airport when flying from Knoxville to Panama City?
Flights via Houston George Bush Intcntl (IAH) offer the most affordable fares, with an average round-trip price of $606. Based on KAYAK data over the past 3 months.
Key details for Knoxville to Panama City flights
Low season | July |
|---|---|
High season | January |
Cheapest flight | $395 |
When to book flights from Knoxville to Panama City
Are your dates flexible? Find out the best times to travel from Knoxville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.
Your Knoxville to Panama City flight questions, answered
Find helpful answers about this route, including flight times, airports, airlines and booking tips.
Your guide to booking Knoxville to Panama City flights
Get tips on when to book, when to fly and what to know before your trip.More options for your flight from Knoxville to Panama City
Complete your trip to Panama City with a hotel stay or car rental
Information on your arrival and departure airports
Cabin class types available on flights from Knoxville to Panama City
Cabin classes available on flights from Knoxville to Panama City. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Find direct flights to and from Knoxville and Panama City
Flights from domestic origins to Panama City
More flights to Panama City. Prices are the lowest found on KAYAK in the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.