TYS - RST

$378 Find Cheap Flights from Knoxville to Rochester - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$378
Typical prices: $338-$573
American Airlines
Sat 11/10Wed 11/14
TYS - RST • 1 stop
When to travel
January
Cheapest • 26% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Minneapolis St Paul (MSP)
Cheapest • Avg $355 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 5h 08m (one-way)
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Insights
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Flight Deals

Cheap Flights from Knoxville to Rochester (TYS-RST)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Rochester

Tue, Nov 10 - Sat, Nov 14
American Airlines Logo
8:52 pm - 11:59 pmTYS  Knoxville McGhee Tyson-RST Rochester
4h 07m1 stop Chicago O'Hare Intl
American Airlines Logo
4:20 pm - 10:51 pmRST  Rochester-TYS Knoxville McGhee Tyson
5h 31m1 stop Chicago O'Hare Intl
$378American Airlines
Thu, Nov 12 - Mon, Nov 16
American Airlines Logo
8:52 pm - 11:59 pmTYS  Knoxville McGhee Tyson-RST Rochester
4h 07m1 stop Chicago O'Hare Intl
American Airlines Logo
12:34 pm - 6:46 pmRST  Rochester-TYS Knoxville McGhee Tyson
5h 12m1 stop Chicago O'Hare Intl
$378American Airlines
Thu, Nov 12 - Mon, Nov 16
American Airlines Logo
8:52 pm - 11:59 pmTYS  Knoxville McGhee Tyson-RST Rochester
4h 07m1 stop Chicago O'Hare Intl
American Airlines Logo
12:34 pm - 9:40 pmRST  Rochester-TYS Knoxville McGhee Tyson
8h 06m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
$384American Airlines
Tue, Nov 10 - Sat, Nov 14
American Airlines Logo
8:52 pm - 11:59 pmTYS  Knoxville McGhee Tyson-RST Rochester
4h 07m1 stop Chicago O'Hare Intl
American Airlines Logo
7:02 am - 5:53 pmRST  Rochester-TYS Knoxville McGhee Tyson
9h 51m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
$384American Airlines
Thu, Nov 12 - Mon, Nov 16
American Airlines Logo
6:50 am - 3:50 pmTYS  Knoxville McGhee Tyson-RST Rochester
10h 00m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
7:02 am - 5:40 pmRST  Rochester-TYS Knoxville McGhee Tyson
9h 38m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
$434American Airlines
Tue, Nov 10 - Sat, Nov 14
American Airlines Logo
2:13 pm - 11:59 pmTYS  Knoxville McGhee Tyson-RST Rochester
10h 46m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
7:02 am - 4:48 pmRST  Rochester-TYS Knoxville McGhee Tyson
8h 46m2 stops Chicago O'Hare Intl Charlotte Douglas
$434American Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Rochester flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Knoxville to Rochester?

Round-trip flights from Knoxville to Rochester typically range from $338 to $573. The lowest price found in the past 5 days was $378, on American Airlines.

What's the cheapest day of the week to fly from Knoxville to Rochester?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Knoxville to Rochester. It’s 20% cheaper than the average day, while Monday is the most expensive, with prices 117% higher.

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Key details for Knoxville to Rochester flights

Cheapest flight

$378
The most popular month to fly with an average 39% increase in travelers.
Round-trip flight from Knoxville to Rochester

When to book flights from Knoxville to Rochester

Are your dates flexible? Find out the best times to travel from Knoxville to Rochester based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Rochester flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Knoxville to Rochester?

    Only Economy Class is available on flights from Knoxville to Rochester.

  • How long is a flight from Knoxville to Rochester?

    There are currently no nonstop flights available from Knoxville to Rochester. Flights with 1 layover take between 5h 08m and 5h 15m in total, depending on the connection.

  • Do I need a passport to fly from Knoxville to Rochester?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Knoxville to Rochester flight?

    Round-trip flights from Knoxville to Rochester range from $338 to $573, with an average of $418 over the past 12 months. Anything below $338 counts as a good deal.

  • Have flight prices from Knoxville to Rochester changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $378 to $434. That means the highest observed fare was about 14% higher than the lowest one.

  • Which airports can I use when flying from Knoxville to Rochester?

    Flights from Knoxville to Rochester usually depart from Knoxville McGhee Tyson (TYS) and arrive at Rochester (RST).

  • Which airports do connecting flights from Knoxville to Rochester pass through?

    Connecting flights from Knoxville to Rochester most commonly pass through:

    • Chicago O'Hare Intl (ORD) - 56% of one-stop connections
    • Minneapolis St Paul (MSP) - 44% of one-stop connections

  • Can I save money by using flexible dates for flights from Knoxville to Rochester?

    Yes. Flexible dates can save you up to 63% on flights from Knoxville to Rochester. Friday is the cheapest departure day at $338 round-trip on average, while Monday is the most expensive at $909, a difference of $571.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Knoxville to Rochester?

    Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 5h 08m, compared with 5h 15m via Minneapolis St Paul (MSP).

  • What is the time difference between Knoxville and Rochester?

    Rochester is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Knoxville to Rochester flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Friday departure and avoid flying on Monday. On this route, Friday flights average $338, about $571 less than Monday fares (63% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to Rochester trip for January. Fares historically average $308 round-trip in that month - typically $601 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Rochester Airport.

    • Comfort Inn & Suites Rochester South Mayo Clinic

More options for your flight from Knoxville to Rochester

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