RST - TYS

$258 Find Cheap Flights from Rochester to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Rochester to Knoxville departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Rochester to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Rochester to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$258
American Airlines
Wed 4/29Sat 5/2
RST - TYS • 1 stop
Cheapest one-way
Multiple Airlines
Thu 1/29
RST - TYS • multi-stop
Top airlines
American Airlines
Cheapest • from $418 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Rochester to Knoxville (RST-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Rochester to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Rochester to Knoxville

Wed, Apr 29 - Sat, May 2
American Airlines Logo
11:36 am - 4:35 pm
RST
-
TYS
3h 59m
1 stop
American Airlines Logo
7:33 pm - 11:56 pm
TYS
-
RST
5h 23m
1 stop
$258American Airlines
Tue, Feb 10 - Fri, Feb 20
Delta Logo
4:39 pm - 11:09 pm
RST
-
TYS
5h 30m
1 stop
Delta Logo
6:35 am - 10:58 am
TYS
-
RST
5h 23m
1 stop
$263Delta
Wed, Apr 29 - Sat, May 2
American Airlines Logo
11:36 am - 5:48 pm
RST
-
TYS
5h 12m
1 stop
American Airlines Logo
4:09 pm - 11:56 pm
TYS
-
RST
8h 47m
2 stops
$264American Airlines
Tue, Feb 10 - Thu, Feb 19
Delta Logo
4:39 pm - 11:09 pm
RST
-
TYS
5h 30m
1 stop
Delta Logo
5:35 am - 10:58 am
TYS
-
RST
6h 23m
2 stops
$269Delta
Tue, Feb 10 - Sat, Feb 21
Delta Logo
4:39 pm - 11:09 pm
RST
-
TYS
5h 30m
1 stop
Delta Logo
5:35 am - 10:58 am
TYS
-
RST
6h 23m
2 stops
$304Delta
Mon, Feb 16 - Sat, Feb 21
American Airlines Logo
5:00 am - 10:45 am
RST
-
TYS
4h 45m
1 stop
American Airlines Logo
7:51 am - 11:02 am
TYS
-
RST
4h 11m
1 stop
$328American Airlines
Wed, Feb 11 - Sat, Feb 21
American Airlines Logo
6:01 am - 12:46 pm
RST
-
TYS
5h 45m
1 stop
American Airlines Logo
7:51 am - 11:02 am
TYS
-
RST
4h 11m
1 stop
$333American Airlines
Mon, Feb 16 - Mon, Feb 23
American Airlines Logo
5:00 am - 10:45 am
RST
-
TYS
4h 45m
1 stop
American Airlines Logo
5:02 pm - 11:48 pm
TYS
-
RST
7h 46m
2 stops
$334American Airlines
Wed, Feb 11 - Mon, Feb 23
American Airlines Logo
6:01 am - 12:46 pm
RST
-
TYS
5h 45m
1 stop
American Airlines Logo
5:02 pm - 11:48 pm
TYS
-
RST
7h 46m
2 stops
$339American Airlines
Wed, Feb 11 - Mon, Feb 23
American Airlines Logo
11:36 am - 9:44 pm
RST
-
TYS
9h 08m
2 stops
American Airlines Logo
5:02 pm - 11:48 pm
TYS
-
RST
7h 46m
2 stops
$344American Airlines
Booking Insights

KAYAK's insights & trends for Rochester to Knoxville flights

Get data-powered insights and trends into flights from Rochester to Knoxville to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Rochester to Knoxville?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Rochester to Knoxville were found on American Airlines ($418) and United Airlines ($459).

Find deals

Good to know

Cheapest flight$258
Flight from Rochester to Knoxville

When to book flights from Rochester to Knoxville

Are your dates flexible? Find out the best times to travel from Rochester to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Rochester to Knoxville

  • What is the cheapest flight from Rochester to Knoxville?

    In the last 3 days, the lowest price for a flight from Rochester to Knoxville was $418 for a round-trip ticket.

  • Do I need a passport to fly between Rochester and Knoxville?

    A passport is not required to fly from Rochester to Knoxville.

  • Which airports will I be using when flying from Rochester to Knoxville?

    When flying out of Rochester you will be using Rochester. You will be landing at Knoxville, also known as Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Rochester to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Rochester to Knoxville?

    oneworld is the only airline alliance operating flights between Rochester and Knoxville.

  • How does KAYAK find such low prices on flights from Rochester to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Rochester to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Rochester to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Rochester is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Rochester to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Rochester with another airline. Booking your flights between Rochester and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Rochester to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Rochester up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Rochester to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Rochester to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Rochester to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11205 reviews
6.9Entertainment
6.4Food
7.5Boarding
7.2Comfort
8.0Crew
Airline reviews

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

4.0 OkayBrandle, Jan 2026
DFW - MCO
Read more American Airlines reviews

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

Everything you need to know for your flight from Rochester to Knoxville

Information on your arrival and departure airports

Rochester (RST)
Knoxville (TYS)