RST - TYS

$339 Find Cheap Flights from Rochester to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Rochester to Knoxville departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Rochester to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Rochester to Knoxville, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Rochester to Knoxville (RST-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Rochester to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Rochester to Knoxville

Sat, Apr 11 - Wed, Apr 15
Delta Logo
11:15 am - 9:32 pmRST-TYS
9h 17m2 stops
Delta Logo
6:45 am - 10:46 amTYS-RST
5h 01m1 stop
$339Delta
Find Deal
Sat, Apr 11 - Wed, Apr 15
Delta Logo
7:00 am - 3:06 pmRST-TYS
7h 06m2 stops
Delta Logo
6:45 am - 10:46 amTYS-RST
5h 01m1 stop
$349Delta
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 12:43 pmRST-TYS
5h 40m1 stop
American Airlines Logo
6:29 pm - 11:59 pmTYS-RST
6h 30m1 stop
$363American Airlines
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 12:43 pmRST-TYS
5h 40m1 stop
American Airlines Logo
4:59 pm - 11:59 pmTYS-RST
8h 00m2 stops
$369American Airlines
Find Deal
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
2:46 pm - 7:26 pmRST-TYS
3h 40m1 stop
American Airlines Logo
11:34 am - 2:35 pmTYS-RST
4h 01m1 stop
$387American Airlines
Find Deal
Sat, Apr 11 - Wed, Apr 15
American Airlines Logo
6:06 am - 7:00 pmRST-TYS
11h 54m2 stops
American Airlines Logo
7:55 am - 2:35 pmTYS-RST
7h 40m2 stops
$398American Airlines
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 12:43 pmRST-TYS
5h 40m1 stop
American Airlines Logo
2:58 pm - 6:09 pmTYS-RST
4h 11m1 stop
$448American Airlines
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 3:49 pmRST-TYS
8h 46m2 stops
American Airlines Logo
4:59 pm - 11:59 pmTYS-RST
8h 00m2 stops
$449American Airlines
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 3:49 pmRST-TYS
8h 46m2 stops
American Airlines Logo
2:58 pm - 6:09 pmTYS-RST
4h 11m1 stop
$454American Airlines
Find Deal
Fri, Nov 21 - Thu, Dec 4
American Airlines Logo
6:03 am - 3:49 pmRST-TYS
8h 46m2 stops
American Airlines Logo
4:59 pm - 11:59 pmTYS-RST
8h 00m2 stops
$459American Airlines
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $339 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$339
Delta
Sat 4/11Wed 4/15
RST - TYS • 2 stops
Cheapest one-way
Multiple Airlines
Thu 10/30
RST - TYS • multi-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Booking Insights

KAYAK's insights & trends for Rochester to Knoxville flights

Get data-powered insights and trends into flights from Rochester to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Rochester to Knoxville?

The average price of all round-trip flights from Rochester to Knoxville clicked on KAYAK for each day over the last 12 months.

For Rochester to Knoxville, Monday is the cheapest day to fly on average and Friday is the most expensive. Flying from Knoxville back to Rochester, the best deals are generally found on Thursday, with Sunday being the most expensive.

Find deals

Good to know

Low seasonMay
Cheapest flight$339
Best time to beat the crowds with an average 50% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Rochester to Knoxville

When to book flights from Rochester to Knoxville

Are your dates flexible? Find out the best times to travel from Rochester to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Rochester to Knoxville

  • What is the cheapest flight from Rochester to Knoxville?

    In the last 3 days, the lowest price for a flight from Rochester to Knoxville was $339 for a round-trip ticket.

  • Do I need a passport to fly between Rochester and Knoxville?

    A passport is not required to fly from Rochester to Knoxville.

  • Which airports will I be using when flying from Rochester to Knoxville?

    When flying out of Rochester you will be using Rochester. You will be landing at Knoxville, also known as Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Rochester to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Rochester to Knoxville?

    oneworld is the only airline alliance operating flights between Rochester and Knoxville.

  • How does KAYAK find such low prices on flights from Rochester to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Rochester to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Rochester to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Rochester is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Rochester to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Rochester with another airline. Booking your flights between Rochester and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Rochester to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Rochester up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Rochester to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Rochester to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Rochester to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11030 reviews
7.5Boarding
6.4Food
8.0Crew
6.9Entertainment
7.2Comfort
Airline reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

8.0 ExcellentKohMeng, Oct 2025DFW - LAX
Read more American Airlines reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

We are too tired and frustrated to comment politely at this point

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

The flight was flawless and we even arrived between 20 and 25 minutes early!

The only thing to like was that we eventually got to our destination

Everything you need to know for your flight from Rochester to Knoxville

Information on your arrival and departure airports

Rochester (RST)
Knoxville (TYS)

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.