Which airports can I use when flying from Rochester to Knoxville?

Flights from Rochester to Knoxville usually depart from Rochester (RST) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Rochester to Knoxville?

Only Economy Class is available on flights from Rochester to Knoxville.

Which airports do connecting flights from Rochester to Knoxville pass through?

Connecting flights from Rochester to Knoxville most commonly pass through: • Chicago O'Hare Intl (ORD) - 76% of one-stop connections • Minneapolis St Paul (MSP) - 24% of one-stop connections

Can I save money by using flexible dates for flights from Rochester to Knoxville?

Yes. Flexible dates can save you up to 52% on flights from Rochester to Knoxville. Friday is the cheapest departure day at $298 round-trip on average, while Tuesday is the most expensive at $616, a difference of $318. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Rochester to Knoxville?

There are currently no nonstop flights available from Rochester to Knoxville. Flights with 1 layover take between 4h 56m and 5h 04m in total, depending on the connection.

Do I need a passport to fly from Rochester to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Rochester to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $348 to $739. That means the highest observed fare was about 2x higher than the lowest one.

How much time can I save by choosing a different layover airport from Rochester to Knoxville?

Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 4h 56m, compared with 5h 04m via Minneapolis St Paul (MSP).

What is the time difference between Rochester and Knoxville?

Knoxville is 1 hour ahead of Rochester (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a Rochester to Knoxville flight?

Round-trip flights from Rochester to Knoxville range from $328 to $450, with an average of $382 over the past 12 months. Anything below $328 counts as a good deal.

How much is a round-trip flight from Rochester to Knoxville?

Round-trip flights from Rochester to Knoxville typically range from $328 to $450. The lowest price found in the past 5 days was $348, on American Airlines.

Which airline is the cheapest to fly from Rochester to Knoxville?

American Airlines ($348) and Delta ($348) are the cheapest airlines to fly round-trip from Rochester to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Rochester to Knoxville?

Chicago O'Hare Intl (ORD) is the most popular layover for the Rochester to Knoxville route. 76% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Rochester to Knoxville?

Flights via Minneapolis St Paul (MSP) offer the most affordable fares, with an average round-trip price of $312. Based on KAYAK data over the past 3 months.

When flying from Rochester to Knoxville which airport offers the shortest layover?

Chicago O'Hare Intl (ORD) had the shortest average connection time for Rochester to Knoxville layovers at 3h 06m over the past 3 months.

$348 CHEAP FLIGHTS from Rochester to Knoxville (RST - TYS)

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Cheapest round-trip

$348

Typical prices: $328-$450

American Airlines

Sun 1/7Mon 1/15

RST - TYS • 1 stop

When to travel

November

Cheapest • 17% price drop

April

Most popular

Good to know

Top layover airports

Minneapolis St Paul (MSP)

Cheapest • Avg $312 (round-trip)

Chicago O'Hare Intl (ORD)

Shortest trip • 4h 56m (one-way)

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Flight Deals

Cheap Flights from Rochester to Knoxville (RST-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Rochester to Knoxville

Thu, Jan 7 - Fri, Jan 15

12:36 pm - 7:07 pmRST Rochester-TYS Knoxville McGhee Tyson

5h 31m1 stop Chicago O'Hare Intl

12:02 pm - 4:05 pmTYS Knoxville McGhee Tyson-RST Rochester

5h 03m1 stop Chicago O'Hare Intl

$348American Airlines

Sun, Jan 31 - Sat, Feb 6

5:19 am - 11:28 amRST Rochester-TYS Knoxville McGhee Tyson

5h 09m1 stop Chicago O'Hare Intl

7:50 am - 12:04 pmTYS Knoxville McGhee Tyson-RST Rochester

5h 14m1 stop Chicago O'Hare Intl

$348American Airlines

Wed, Feb 17 - Sun, Feb 21

4:25 pm - 9:37 pmRST Rochester-TYS Knoxville McGhee Tyson

4h 12m1 stop Minneapolis St Paul

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$348Delta

Wed, Mar 17 - Sun, Mar 21

4:25 pm - 9:37 pmRST Rochester-TYS Knoxville McGhee Tyson

4h 12m1 stop Minneapolis St Paul

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$348Delta

Wed, Mar 17 - Sun, Mar 21

4:25 pm - 9:37 pmRST Rochester-TYS Knoxville McGhee Tyson

4h 12m1 stop Minneapolis St Paul

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$348Delta

Thu, Jan 7 - Fri, Jan 15

12:36 pm - 10:20 pmRST Rochester-TYS Knoxville McGhee Tyson

8h 44m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

7:50 am - 12:04 pmTYS Knoxville McGhee Tyson-RST Rochester

5h 14m1 stop Chicago O'Hare Intl

$354American Airlines

Thu, Jan 7 - Fri, Jan 15

5:19 am - 3:21 pmRST Rochester-TYS Knoxville McGhee Tyson

9h 02m2 stops Chicago O'Hare Intl Charlotte Douglas

8:56 pm - 12:25 amTYS Knoxville McGhee Tyson-RST Rochester

4h 29m1 stop Chicago O'Hare Intl

$354American Airlines

Thu, Mar 18 - Sun, Mar 21

4:25 pm - 9:37 pmRST Rochester-TYS Knoxville McGhee Tyson

4h 12m1 stop Minneapolis St Paul

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$518Delta

Thu, Mar 18 - Sun, Mar 21

4:25 pm - 9:37 pmRST Rochester-TYS Knoxville McGhee Tyson

4h 12m1 stop Minneapolis St Paul

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$518Delta

Thu, Mar 18 - Sun, Mar 21

6:10 am - 4:08 pmRST Rochester-TYS Knoxville McGhee Tyson

8h 58m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

7:55 am - 11:03 amTYS Knoxville McGhee Tyson-RST Rochester

4h 08m1 stop Minneapolis St Paul

$524Delta

Booking Insights

Price, demand and travel trends for Rochester to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Rochester to Knoxville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Rochester to Knoxville departing in january.

Find deals

Low season	January
High season	April
Cheapest flight	$348

Beat the crowds with an average 90% drop in travelers.

The most popular month to fly with an average 71% increase in travelers.

Round-trip flight from Rochester to Knoxville

When to book flights from Rochester to Knoxville

Are your dates flexible? Find out the best times to travel from Rochester to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Rochester to Knoxville?
Only Economy Class is available on flights from Rochester to Knoxville.
How long is a flight from Rochester to Knoxville?
There are currently no nonstop flights available from Rochester to Knoxville. Flights with 1 layover take between 4h 56m and 5h 04m in total, depending on the connection.
Do I need a passport to fly from Rochester to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Rochester to Knoxville flight?
Round-trip flights from Rochester to Knoxville range from $328 to $450, with an average of $382 over the past 12 months. Anything below $328 counts as a good deal.
Have flight prices from Rochester to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $348 to $739. That means the highest observed fare was about 2x higher than the lowest one.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates averaging $80 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from Rochester to Knoxville?
Flights from Rochester to Knoxville usually depart from Rochester (RST) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from Rochester to Knoxville pass through?
Connecting flights from Rochester to Knoxville most commonly pass through:

• Chicago O'Hare Intl (ORD) - 76% of one-stop connections
• Minneapolis St Paul (MSP) - 24% of one-stop connections
Can I save money by using flexible dates for flights from Rochester to Knoxville?
Yes. Flexible dates can save you up to 52% on flights from Rochester to Knoxville. Friday is the cheapest departure day at $298 round-trip on average, while Tuesday is the most expensive at $616, a difference of $318.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Rochester to Knoxville?
Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 4h 56m, compared with 5h 04m via Minneapolis St Paul (MSP).
What is the time difference between Rochester and Knoxville?
Knoxville is 1 hour ahead of Rochester (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Friday departure and avoid flying on Tuesday. On this route, Friday flights average $298, about $318 less than Tuesday fares (52% savings) based on the last 12 months.
If you can choose when to travel, plan your Rochester to Knoxville trip for November. Fares historically average $318 round-trip in that month - typically $453 less than the most expensive month, which is June (based on the last 12 months).

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RST - TYS

$348 Find Cheap Flights from Rochester to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Rochester to Knoxville (RST-TYS)

Recent round-trip flight deals from Rochester to Knoxville

Recent one-way flight deals from Rochester to Knoxville

Price, demand and travel trends for Rochester to Knoxville flights

How much is a round-trip flight from Rochester to Knoxville?

Which airline is the cheapest to fly from Rochester to Knoxville?

What’s the most popular layover airport when flying from Rochester to Knoxville?

What is the cheapest layover airport when flying from Rochester to Knoxville?

When flying from Rochester to Knoxville which airport offers the shortest layover?

Key details for Rochester to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Rochester to Knoxville

Your Rochester to Knoxville flight questions, answered

Your guide to booking Rochester to Knoxville flights

More options for your flight from Rochester to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Rochester to Knoxville

Find direct flights to and from Rochester and Knoxville

Flights from domestic origins to Knoxville

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