TYS - FSD

$269 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$269
American Airlines
Wed 3/25Sat 3/28
TYS - FSD • 1 stop
Top airlines
American Airlines
Cheapest • from $269 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
7:40 am - 1:36 pm
TYS
-
FSD
6h 56m
1 stop
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$269American Airlines
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:00 am - 11:38 am
TYS
-
FSD
7h 38m
2 stops
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$274American Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
4:09 pm - 9:54 pm
TYS
-
FSD
6h 45m
1 stop
American Airlines Logo
6:00 am - 12:30 pm
FSD
-
TYS
5h 30m
1 stop
$294American Airlines
Thu, May 7 - Sat, May 16
American Airlines Logo
4:09 pm - 9:54 pm
TYS
-
FSD
6h 45m
1 stop
American Airlines Logo
5:28 pm - 11:56 pm
FSD
-
TYS
5h 28m
1 stop
$320American Airlines
Fri, Feb 27 - Tue, Mar 3
Delta Logo
6:35 am - 10:08 am
TYS
-
FSD
4h 33m
1 stop
Delta Logo
4:19 pm - 11:12 pm
FSD
-
TYS
5h 53m
1 stop
$324Delta
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
7:40 am - 11:38 am
TYS
-
FSD
4h 58m
1 stop
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$326American Airlines
Fri, Feb 27 - Tue, Mar 3
Delta Logo
6:35 am - 10:08 am
TYS
-
FSD
4h 33m
1 stop
Delta Logo
8:05 am - 8:55 pm
FSD
-
TYS
11h 50m
2 stops
$329Delta
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:00 am - 11:38 am
TYS
-
FSD
7h 38m
2 stops
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$331American Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
5:00 am - 11:38 am
TYS
-
FSD
7h 38m
2 stops
American Airlines Logo
6:45 am - 6:13 pm
FSD
-
TYS
10h 28m
2 stops
$337American Airlines
Fri, May 1 - Mon, May 4
Multiple Airlines Logo
7:30 am - 5:21 pm
TYS
-
FSD
10h 51m
1 stop
Multiple Airlines Logo
6:38 pm - 10:36 am
FSD
-
TYS
38h 58m
2 stops
$353Multiple Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Sioux Falls?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Sioux Falls were found on American Airlines ($269) and Delta ($324).

Good to know

Low seasonFebruary
Cheapest flight$269
Best time to beat the crowds with an average 35% drop in price.
Most popular time to fly with an average 56% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $269 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $470 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9289 reviews
7.7Boarding
7.1Entertainment
7.3Comfort
8.1Crew
6.6Food
Airline reviews

Very old flight - time to retire it for newer airplanes

10.0 ExcellentSrinivas, Feb 2026
BOS - IAH
Read more United Airlines reviews

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Didn't get a seat assignment until the last minute even though i picked a seat.

American has been able to implement an algorithm that makes it possible for nearly every one of my evening flights to be late. Congratulations!

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

The flight was fine, once we got underway. It was more than hour delayed

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

Waited for oxygen tanks for 30 minutes after boarding was complete.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

The flight was on time/early, attentive crew, and everything overall went smoothly. Disappointed that WIFI was not working for the flight.

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports