TYS - FSD

$269 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$269
Overall average: $353
American Airlines
Wed 3/25Sat 3/28
TYS - FSD • 1 stop
Top airlines
American Airlines
Cheapest • from $269 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Dallas (DFW)
Cheapest • Avg $434 (round-trip)
Chicago (ORD)
Shortest trip • 5h 10m (one-way)
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 33% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
4:29 pm - 9:40 pm
TYS
-
FSD
6h 11m
1 stop
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$269American Airlines
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:00 am - 1:36 pm
TYS
-
FSD
9h 36m
2 stops
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$274American Airlines
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
6:45 am - 10:46 am
TYS
-
FSD
5h 01m
1 stop
United Airlines Logo
3:10 pm - 8:48 pm
FSD
-
TYS
4h 38m
1 stop
$279United Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
7:51 am - 11:42 am
TYS
-
FSD
4h 51m
1 stop
American Airlines Logo
2:06 pm - 9:24 pm
FSD
-
TYS
6h 18m
1 stop
$299American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
5:40 am - 12:41 pm
TYS
-
FSD
8h 01m
1 stop
American Airlines Logo
12:14 pm - 11:50 pm
FSD
-
TYS
10h 36m
2 stops
$305American Airlines
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:40 am - 12:41 pm
TYS
-
FSD
8h 01m
1 stop
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$326American Airlines
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:00 am - 1:36 pm
TYS
-
FSD
9h 36m
2 stops
American Airlines Logo
5:21 pm - 11:51 pm
FSD
-
TYS
5h 30m
1 stop
$331American Airlines
Fri, Mar 6 - Mon, Mar 9
Allegiant Air Logo
8:54 pm - 1:46 pm
TYS
-
FSD
17h 52m
1 stop
Allegiant Air Logo
6:11 pm - 10:10 am
FSD
-
TYS
14h 59m
1 stop
$361Allegiant Air
Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
12:22 pm - 11:03 pm
TYS
-
FSD
11h 41m
2 stops
American Airlines Logo
5:19 pm - 12:28 am
FSD
-
TYS
6h 09m
1 stop
$362American Airlines
Wed, Mar 25 - Sat, Mar 28
American Airlines Logo
5:00 am - 11:38 am
TYS
-
FSD
7h 38m
2 stops
American Airlines Logo
2:07 pm - 11:50 pm
FSD
-
TYS
8h 43m
2 stops
$387American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to Sioux Falls?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Sioux Falls, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Sioux Falls is April, where tickets cost $268 (return) on average. On the other hand, the most expensive months are June and July, where the average cost of round-trip tickets is $643 and $517 respectively.

Good to know

Low seasonFebruary
Cheapest flight$269
Best time to beat the crowds with an average 33% drop in price.
Most popular time to fly with an average 61% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $269 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $470 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9321 reviews
7.1Entertainment
7.3Comfort
6.6Food
7.7Boarding
8.1Crew
Airline reviews

Airport terminal was outdated, flight was on a small jet with no wifi

2.0 MediocreCraig, Feb 2026
IAH - STL
Read more United Airlines reviews

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Waiting for gate in RDU for more than 20mins is crazy.

Flight was on time and there was an empty seat next to me. That makes for a good flight!

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

I like that the flight attendant was very attentive and helpful. The meal menu could have more of an variety of food choices.

Everything was good. Flight was very full so crew was busy. After we boarded and plane pulled away from the gate, we were delayed about 40 minutes- sitting on the runway - due to weather en route or at the destination. While weather is not the fault of the airline- it’s terrible to sit on a plane and not moving.

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

No Snacks or Entertainment. The flight was short, snacks should still be given.

We lost a day of our vacation because AA did not get the plane to the gate on time. Even though the gate attendant was very clear that it was not weather related, AA would do nothing because there was some snow that day. They basically said the gate attendant was wrong even though she was on the front line of the situation and they were not.

See prior comment about how Kayak mishandled my reservation and delayed my arrival by 6 hours.

American Airlines was great and worked very hard to change my ticket so I could get an earlier, direct flight back to Dallas. However, I was informed that Kayak made mistakes with my itinerary and classified my ticket as desiring to be on the earlier flight instead of taking the necessary step of calling AA to get me on the standby list. This ended up keeping me from being added to the standby list and delayed me getting home by 6 hours. I am happy to discuss this further with Kayak so they can correct their procedures so this won't happen again.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports