TYS - FSD

$143 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$307
Typical prices: $513-$470
Delta
Thu 10/15Tue 10/20
TYS - FSD • 1 stop
Cheapest one-way
$143
Allegiant Air
Mon 6/1
TYS - FSD • 1 stop
Top airlines
Cheapest • from $307 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $399 (round-trip)
Shortest trip • 5h 10m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 35% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Thu, Oct 15 - Tue, Oct 20
Delta Logo
6:15 pm - 10:51 pm
TYS
-
FSD
5h 36m
1 stop
Delta Logo
5:25 am - 11:06 am
FSD
-
TYS
4h 41m
1 stop
$307Delta
Fri, Aug 28 - Mon, Aug 31
Delta Logo
6:30 am - 12:38 pm
TYS
-
FSD
7h 08m
1 stop
Delta Logo
10:58 am - 4:34 pm
FSD
-
TYS
4h 36m
1 stop
$319Delta
Sat, Aug 29 - Mon, Aug 31
Delta Logo
6:00 am - 12:38 pm
TYS
-
FSD
7h 38m
2 stops
Delta Logo
10:58 am - 4:34 pm
FSD
-
TYS
4h 36m
1 stop
$322Delta
Fri, Aug 28 - Sun, Aug 30
Delta Logo
5:45 am - 12:38 pm
TYS
-
FSD
7h 53m
2 stops
Delta Logo
5:20 am - 1:34 pm
FSD
-
TYS
7h 14m
1 stop
$324Delta
Sat, Aug 29 - Mon, Aug 31
Delta Logo
6:00 am - 12:38 pm
TYS
-
FSD
7h 38m
2 stops
Delta Logo
5:15 am - 3:07 pm
FSD
-
TYS
8h 52m
2 stops
$327Delta
Fri, Aug 28 - Sun, Aug 30
Delta Logo
5:45 am - 12:38 pm
TYS
-
FSD
7h 53m
2 stops
Delta Logo
5:04 am - 1:34 pm
FSD
-
TYS
7h 30m
2 stops
$329Delta
Fri, Aug 28 - Sun, Aug 30
Delta Logo
5:45 am - 12:38 pm
TYS
-
FSD
7h 53m
2 stops
Delta Logo
5:20 am - 11:11 am
FSD
-
TYS
4h 51m
1 stop
$334Delta
Fri, Aug 28 - Mon, Aug 31
Delta Logo
5:45 am - 12:38 pm
TYS
-
FSD
7h 53m
2 stops
Delta Logo
1:20 pm - 11:47 pm
FSD
-
TYS
9h 27m
2 stops
$340Delta
Fri, Aug 28 - Sun, Aug 30
Delta Logo
5:45 am - 12:38 pm
TYS
-
FSD
7h 53m
2 stops
Delta Logo
5:04 am - 1:34 pm
FSD
-
TYS
7h 30m
2 stops
$349Delta
Thu, Oct 15 - Tue, Oct 20
Delta Logo
7:55 am - 12:11 pm
TYS
-
FSD
5h 16m
1 stop
Delta Logo
1:00 pm - 11:46 pm
FSD
-
TYS
9h 46m
2 stops
$352Delta
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Sioux Falls?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Sioux Falls departing in June.

What is the cheapest month to fly from Knoxville to Sioux Falls?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Sioux Falls, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Sioux Falls is February, where tickets cost $269 (return) on average. On the other hand, the most expensive months are September and July, where the average cost of round-trip tickets is $570 and $517 respectively.

Good to know

Low seasonFebruary
Cheapest flight$143
Best time to beat the crowds with an average 35% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $143 for a one-way ticket and $307 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $443 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9699 reviews
8.1Crew
7.1Entertainment
7.3Comfort
7.7Boarding
6.6Food
Airline reviews

It was good overall except from Omaha to Denver when flight a was a repeatedly delayed apparently due to some issue at Denver. Communications could have been handled better. I had to board then deboard with luggage and board again

6.0 GoodAnonymous, May 2026
OMA - DEN
Read more United Airlines reviews

It was good overall except from Omaha to Denver when flight a was a repeatedly delayed apparently due to some issue at Denver. Communications could have been handled better. I had to board then deboard with luggage and board again

Left an hour and a half after the listed time. Up side was it had TV screens on the seat.

No screens or meal options. Freezing cold. Dirty seats. Left late.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Overall a good experience, but no wifi available for free or for purchase and we got wet from condensation or other water source during descent.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

The small flights with Valet Luggage has a poor service

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports