TYS - FSD

$284 Find Cheap Flights from Knoxville to Sioux Falls - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$337
Typical prices: $348-$514
United Airlines
Tue 12/25Tue 1/9
TYS - FSD • 1 stop
Cheapest one-way
$284
Typical prices: $261-$389
American Airlines
Fri 11/30
TYS - FSD • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 37% price drop
February
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $368 (round-trip)
Minneapolis St Paul (MSP)
Shortest trip • 5h 06m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Fri, Dec 25 - Sat, Jan 9
United Airlines Logo
5:57 pm - 11:26 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
6h 29m1 stop Chicago O'Hare Intl
United Airlines Logo
7:30 am - 1:20 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 50m1 stop Chicago O'Hare Intl
$337United Airlines
Thu, Dec 24 - Thu, Dec 31
American Airlines Logo
5:30 am - 11:24 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
6h 54m1 stop Dallas/Fort Worth
American Airlines Logo
5:00 am - 11:02 amFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
5h 02m1 stop Chicago O'Hare Intl
$339American Airlines
Fri, Dec 25 - Sat, Jan 9
Delta Logo
7:25 am - 4:19 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
9h 54m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul
Delta Logo
4:09 pm - 9:37 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 28m1 stop Minneapolis St Paul
$342Delta
Thu, Dec 10 - Sat, Jan 16
American Airlines Logo
8:46 pm - 12:46 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
5h 00m1 stop Chicago O'Hare Intl
American Airlines Logo
12:37 pm - 10:51 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
9h 14m2 stops Chicago O'Hare Intl Charlotte Douglas
$342American Airlines
Thu, Dec 24 - Thu, Dec 31
American Airlines Logo
1:01 pm - 10:57 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
10h 56m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
5:00 am - 11:02 amFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
5h 02m1 stop Chicago O'Hare Intl
$344American Airlines
Fri, Nov 6 - Sun, Nov 8
United Airlines Logo
5:40 pm - 9:37 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 57m1 stop Chicago O'Hare Intl
United Airlines Logo
5:55 am - 4:59 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
10h 04m2 stops Denver Intl Chicago O'Hare Intl
$405United Airlines
Thu, Dec 17 - Mon, Dec 21
Multiple Airlines Logo
5:26 pm - 9:26 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
17h 00m1 stop Punta Gorda
Multiple Airlines Logo
7:50 pm - 10:46 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
25h 56m2 stops Nashville Intl Orlando
$450Multiple Airlines
Thu, Dec 17 - Mon, Dec 21
Allegiant Air Logo
5:26 pm - 9:26 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
17h 00m1 stop Punta Gorda
Allegiant Air Logo
5:37 pm - 8:36 amFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
13h 59m1 stop Fort Lauderdale
$454Allegiant Air
Tue, Nov 17 - Tue, Nov 24
Delta Logo
4:00 pm - 7:56 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 56m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:31 am - 4:20 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 49m1 stop Minneapolis St Paul
$488Delta
Tue, Nov 17 - Tue, Nov 24
Delta Logo
5:10 pm - 11:00 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
6h 50m2 stops Detroit Metropolitan Wayne County Minneapolis St Paul
Delta Logo
8:31 am - 4:20 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 49m1 stop Minneapolis St Paul
$493Delta
Booking Insights

Price, demand and travel trends for Knoxville to Sioux Falls flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Knoxville to Sioux Falls?

Round-trip flights from Knoxville to Sioux Falls typically range from $348 to $514. The lowest price found in the past 5 days was $337, on United Airlines.

What’s the cheapest month to fly from Knoxville to Sioux Falls?

•February is the cheapest month to fly from Knoxville to Sioux Falls at $269 round-trip.
•June ($850) and September ($570) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 215% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Knoxville to Sioux Falls flights

Low season

May

Cheapest flight

$284
Beat the crowds with an average 54% drop in travelers.
The most popular month to fly with an average 31% increase in travelers.
One-way flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Sioux Falls flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Knoxville to Sioux Falls?

    Only Economy Class is available on flights from Knoxville to Sioux Falls.

  • How long is a flight from Knoxville to Sioux Falls?

    A nonstop flight from Knoxville to Sioux Falls takes 00m, covering 863 miles.

  • Do I need a passport to fly from Knoxville to Sioux Falls?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Knoxville to Sioux Falls flight?

    Round-trip flights from Knoxville to Sioux Falls range from $348 to $514, with an average of $428 over the past 12 months. Anything below $348 counts as a good deal.

  • Have flight prices from Knoxville to Sioux Falls changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $337 to $2,676. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Knoxville to Sioux Falls looking right now?

    One-way fares from Knoxville to Sioux Falls are currently higher than usual. Average one-way flight prices are about $497, which is 66% above the typical average for this route.

  • What car rental options are available at Sioux Falls Joe Foss Field Airport (FSD)?

    Sioux Falls Joe Foss Field Airport (FSD) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:

    • Hertz
    • Alamo
    • Enterprise Rent-A-Car
    • Budget
    • Avis

  • Which airports can I use when flying from Knoxville to Sioux Falls?

    Flights from Knoxville to Sioux Falls usually depart from Knoxville McGhee Tyson (TYS) and arrive at Sioux Falls Joe Foss Field (FSD).

  • Which airports do connecting flights from Knoxville to Sioux Falls pass through?

    One-stop flights from Knoxville to Sioux Falls most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 64% of one-stop connections
    • Dallas/Fort Worth (DFW) - 25% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 7% of one-stop connections
    • Minneapolis St Paul (MSP) - 4% of one-stop connections

  • Can I save money by using flexible dates for flights from Knoxville to Sioux Falls?

    Yes. Flexible dates can save you up to 42% on flights from Knoxville to Sioux Falls. Thursday is the cheapest departure day at $339 round-trip on average, while Sunday is the most expensive at $584, a difference of $245.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Knoxville to Sioux Falls?

    Flying via Minneapolis St Paul (MSP) gives the shortest average 1-stop total travel time at 5h 06m, compared with 5h 10m via Chicago O'Hare Intl (ORD) and 6h 04m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Knoxville and Sioux Falls?

    Sioux Falls is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Knoxville to Sioux Falls flights

Get tips on when to book, when to fly and what to know before your trip.

More options for your flight from Knoxville to Sioux Falls

Complete your trip to Sioux Falls with a hotel stay or car rental

Car rentals in Sioux Falls
Hotels in Sioux Falls
Vacations in Sioux Falls