TYS - FSD

$315 Find Cheap Flights from Knoxville to Sioux Falls - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$315
Typical prices: $340-$514
United Airlines
Sun 9/16Wed 9/19
TYS - FSD • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 38% price drop
August
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $372 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 5h 05m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Wed, Sep 9 - Sat, Sep 12
American Airlines Logo
8:00 am - 11:41 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 41m1 stop Chicago O'Hare Intl
American Airlines Logo
6:00 am - 2:29 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
7h 29m1 stop Dallas/Fort Worth
$315American Airlines
Wed, Sep 16 - Sat, Sep 19
United Airlines Logo
6:00 pm - 11:12 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
6h 12m1 stop Chicago O'Hare Intl
United Airlines Logo
1:33 pm - 10:44 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
8h 11m1 stop Denver Intl
$315United Airlines
Fri, Nov 13 - Sun, Nov 15
American Airlines Logo
8:48 pm - 12:39 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 51m1 stop Chicago O'Hare Intl
American Airlines Logo
3:26 pm - 11:47 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
7h 21m1 stop Chicago O'Hare Intl
$319American Airlines
Wed, Sep 9 - Sat, Sep 12
American Airlines Logo
3:53 pm - 12:29 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
9h 36m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
6:00 am - 2:29 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
7h 29m1 stop Dallas/Fort Worth
$320American Airlines
Wed, Sep 9 - Sat, Sep 12
American Airlines Logo
3:53 pm - 12:29 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
9h 36m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
12:56 pm - 10:50 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
8h 54m2 stops Dallas/Fort Worth Charlotte Douglas
$325American Airlines
Wed, Sep 16 - Sat, Sep 19
American Airlines Logo
6:00 am - 12:16 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
7h 16m1 stop Dallas/Fort Worth
American Airlines Logo
12:06 pm - 7:43 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 37m1 stop Chicago O'Hare Intl
$332American Airlines
Fri, Sep 4 - Mon, Sep 7
United Airlines Logo
6:02 pm - 11:22 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
6h 20m1 stop Chicago O'Hare Intl
United Airlines Logo
7:47 am - 1:17 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 30m1 stop Chicago O'Hare Intl
$334United Airlines
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
7:00 am - 10:29 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 29m1 stop Chicago O'Hare Intl
United Airlines Logo
3:06 pm - 8:53 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 47m1 stop Chicago O'Hare Intl
$349United Airlines
Fri, Sep 4 - Tue, Sep 8
American Airlines Logo
6:05 pm - 12:30 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
7h 25m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
5:23 pm - 11:18 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 55m1 stop Chicago O'Hare Intl
$354American Airlines
Tue, Sep 1 - Sat, Sep 5
American Airlines Logo
10:08 am - 7:59 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
10h 51m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
5:23 pm - 11:22 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 59m1 stop Chicago O'Hare Intl
$354American Airlines
Booking Insights

Price, demand and travel trends for Knoxville to Sioux Falls flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Knoxville to Sioux Falls with more confidence.

How much is a round-trip flight from Knoxville to Sioux Falls?

Round-trip flights from Knoxville to Sioux Falls start at $315. Prices are below average for this route right now, with typical round-trip fares ranging from $340 to $514. The lowest price found in the past 5 days was $315 on United Airlines.

What is the cheapest month to fly from Knoxville to Sioux Falls?

  • February is the cheapest month to fly from Knoxville to Sioux Falls at $269 round-trip.
  • June ($850) and September ($572) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 215% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Knoxville to Sioux Falls flights

Low season

May

Cheapest flight

$315
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Sioux Falls flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Knoxville to Sioux Falls?

    Flights from Knoxville to Sioux Falls usually depart from Knoxville McGhee Tyson (TYS) and arrive at Sioux Falls Joe Foss Field (FSD).

  • What cabin classes can I book on flights from Knoxville to Sioux Falls?

    Only Economy Class is available on flights from Knoxville to Sioux Falls.

  • Which airports do connecting flights from Knoxville to Sioux Falls pass through?

    One-stop flights from Knoxville to Sioux Falls most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 69% of one-stop connections
    • Dallas/Fort Worth (DFW) - 21% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 7% of one-stop connections
    • Minneapolis St Paul (MSP) - 3% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Knoxville to Sioux Falls?

    Yes. Being flexible with your travel dates can save you up to 42% on the Knoxville to Sioux Falls route. Thursday is the cheapest departure day at $339 round-trip on average, while Sunday is the most expensive at $584, a difference of $245. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Knoxville to Sioux Falls?

    A nonstop flight from Knoxville to Sioux Falls takes 0h 00m, covering 863 miles.

  • What are the earliest and latest flights from Knoxville to Sioux Falls?

    These are the earliest and latest flight times available from Knoxville to Sioux Falls:

    • Earliest: departs at 12:00 am and lands at 12:00 am
    • Latest: departs at 12:00 am and lands at 12:00 am.

    The flight takes about 0h 00m.

  • Do I need a passport to fly from Knoxville to Sioux Falls?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Knoxville to Sioux Falls changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $315 to $715. That means the highest observed fare was about 2x higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Knoxville to Sioux Falls?

    Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 5h 05m, compared with 5h 06m via Minneapolis St Paul (MSP) and 6h 00m via Dallas/Fort Worth (DFW).

  • What is the time difference between Knoxville and Sioux Falls?

    Sioux Falls is 1 hour behind Knoxville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Sioux Falls Joe Foss Field Airport (FSD)?

    Sioux Falls Joe Foss Field Airport (FSD) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:
    · Hertz
    · Alamo
    · Enterprise Rent-A-Car
    · Budget
    · Avis

  • How much should I expect to pay for a Knoxville to Sioux Falls flight?

    Round-trip flights from Knoxville to Sioux Falls range from $340 to $514, with an average of $434 over the past 12 months. Anything below $340 counts as a good deal.

Your guide to booking Knoxville to Sioux Falls flights

Get tips on when to book, when to fly and what to know before your trip.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports

Knoxville (TYS)
Sioux Falls (FSD)