TYS - FSD

$153 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Fri, Oct 17 - Tue, Oct 21
American Airlines Logo
2:21 pm - 9:15 pmTYS-FSD
7h 54m1 stop
American Airlines Logo
5:05 pm - 12:23 amFSD-TYS
6h 18m1 stop
$441American Airlines
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Sat, Dec 20 - Sat, Jan 3
American Airlines Logo
4:21 pm - 9:17 pmTYS-FSD
5h 56m1 stop
American Airlines Logo
10:41 am - 3:58 pmFSD-TYS
4h 17m1 stop
$482American Airlines
Find Deal
Sat, Dec 20 - Sat, Jan 3
American Airlines Logo
4:21 pm - 9:17 pmTYS-FSD
5h 56m1 stop
American Airlines Logo
10:41 am - 3:58 pmFSD-TYS
4h 17m1 stop
$499American Airlines
Find Deal
Sat, Dec 20 - Sat, Jan 3
American Airlines Logo
4:21 pm - 9:17 pmTYS-FSD
5h 56m1 stop
American Airlines Logo
10:41 am - 6:59 pmFSD-TYS
7h 18m2 stops
$504American Airlines
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Fri, Oct 3 - Sun, Oct 5
United Airlines Logo
7:00 am - 10:22 pmTYS-FSD
16h 22m1 stop
United Airlines Logo
8:00 am - 1:25 pmFSD-TYS
4h 25m1 stop
$508United Airlines
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Fri, Oct 17 - Tue, Oct 21
United Airlines Logo
7:26 pm - 10:22 pmTYS-FSD
27h 56m2 stops
United Airlines Logo
3:12 pm - 10:50 pmFSD-TYS
6h 38m1 stop
$523United Airlines
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Sat, Dec 20 - Sat, Jan 3
American Airlines Logo
4:21 pm - 9:17 pmTYS-FSD
5h 56m1 stop
American Airlines Logo
10:41 am - 6:59 pmFSD-TYS
7h 18m2 stops
$526American Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
United Airlines Logo
4:40 pm - 11:15 pmTYS-FSD
7h 35m1 stop
United Airlines Logo
6:00 am - 3:06 pmFSD-TYS
8h 06m1 stop
$529United Airlines
Find Deal
Fri, Oct 17 - Wed, Oct 22
American Airlines Logo
2:21 pm - 9:15 pmTYS-FSD
7h 54m1 stop
American Airlines Logo
5:05 pm - 12:23 amFSD-TYS
6h 18m1 stop
$539American Airlines
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Tue, Oct 21 - Thu, Oct 23
Delta Logo
12:47 pm - 10:56 pmTYS-FSD
11h 09m2 stops
Delta Logo
5:30 am - 1:42 pmFSD-TYS
7h 12m1 stop
$664Delta
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Everything you should know

Top airlines
American Airlines
Cheapest • from $441 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$441
Typical prices: $443-542
American Airlines
Fri 10/17Tue 10/21
TYS - FSD • 1 stop
Cheapest one-way
$153
Multiple Airlines
Sun 11/16
TYS - FSD • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
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Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to Sioux Falls?

The average price of all round-trip flights from Knoxville to Sioux Falls clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Sioux Falls on a Friday and more expensive on a Thursday. On your return trip to Knoxville, you should consider flying back on a Saturday, and avoid Thursdays for better deals.

Find deals

Good to know

Cheapest flight$153
Most popular time to fly with an average 48% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $153 for a one-way ticket and $441 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Knoxville and Sioux Falls, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.5Boarding
8.0Crew
6.9Entertainment
7.2Comfort
6.4Food
Airline reviews

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

10.0 ExcellentDouglas, Sep 2025SLC - CLT
Read more American Airlines reviews

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports

Knoxville (TYS)
Sioux Falls (FSD)

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