TYS - FSD

$203 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$269
American Airlines
Sat 4/25Sat 5/2
TYS - FSD • 1 stop
Cheapest one-way
$203
Allegiant Air
Fri 5/8
TYS - FSD • 1 stop
Top airlines
American Airlines
Cheapest • from $269 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Sat, Apr 25 - Sat, May 2
American Airlines Logo
4:09 pm - 10:03 pm
TYS
-
FSD
6h 54m
1 stop
American Airlines Logo
6:00 am - 12:30 pm
FSD
-
TYS
5h 30m
1 stop
$269American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
3:58 pm - 11:05 pm
TYS
-
FSD
8h 07m
2 stops
American Airlines Logo
5:28 pm - 11:56 pm
FSD
-
TYS
5h 28m
1 stop
$274American Airlines
Tue, Feb 3 - Sat, Feb 7
United Airlines Logo
11:10 am - 5:18 pm
TYS
-
FSD
7h 08m
1 stop
United Airlines Logo
7:30 am - 1:24 pm
FSD
-
TYS
4h 54m
1 stop
$279United Airlines
Tue, Feb 3 - Sat, Feb 7
Delta Logo
5:00 pm - 11:10 pm
TYS
-
FSD
7h 10m
1 stop
Delta Logo
1:02 pm - 11:45 pm
FSD
-
TYS
9h 43m
2 stops
$284Delta
Tue, Feb 3 - Sat, Feb 7
Delta Logo
5:40 am - 12:22 pm
TYS
-
FSD
7h 42m
2 stops
Delta Logo
1:02 pm - 11:45 pm
FSD
-
TYS
9h 43m
2 stops
$290Delta
Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
7:40 am - 11:38 am
TYS
-
FSD
4h 58m
1 stop
American Airlines Logo
2:06 pm - 9:24 pm
FSD
-
TYS
6h 18m
1 stop
$295American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
3:58 pm - 11:05 pm
TYS
-
FSD
8h 07m
2 stops
American Airlines Logo
1:46 pm - 11:59 pm
FSD
-
TYS
9h 13m
2 stops
$337American Airlines
Tue, Feb 3 - Sat, Feb 7
United Airlines Logo
11:10 am - 8:24 pm
TYS
-
FSD
10h 14m
2 stops
United Airlines Logo
7:30 am - 1:24 pm
FSD
-
TYS
4h 54m
1 stop
$354United Airlines
Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
7:40 am - 11:38 am
TYS
-
FSD
4h 58m
1 stop
American Airlines Logo
6:50 am - 5:16 pm
FSD
-
TYS
9h 26m
2 stops
$383American Airlines
Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
6:45 am - 10:46 am
TYS
-
FSD
5h 01m
1 stop
United Airlines Logo
3:15 pm - 8:37 pm
FSD
-
TYS
4h 22m
1 stop
$389United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Sioux Falls?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Sioux Falls were found on American Airlines ($269) and United Airlines ($279).

Good to know

Low seasonFebruary
Cheapest flight$203
Best time to beat the crowds with an average 34% drop in price.
Most popular time to fly with an average 57% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $203 for a one-way ticket and $269 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $448 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9188 reviews
8.1Crew
7.3Comfort
7.7Boarding
7.1Entertainment
6.6Food
Airline reviews

Very good. Because of the delays with my previous flight, I missed my connection, but I was able to book another flight through the United app easily.

10.0 ExcellentAnonymous, Jan 2026
IAD - ATL
Read more United Airlines reviews

Very good. Because of the delays with my previous flight, I missed my connection, but I was able to book another flight through the United app easily.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

The flight crew where really good. Better then the crew from BNE to SFO

Delayed, toilets did not flush, pilot parked to far away from Gate

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

Concern Regarding Significant Gate Delay and Jet Bridge Issue Dear Customer Relations Team, I am writing to express my disappointment with the experience I had on my recent flight AA 2414 on Sunday January 18, 2026. What should have been a routine departure turned into a frustrating and avoidable delay due to an issue with the jet bridge at the gate. As a result, the flight was delayed by approximately 90 minutes while multiple gate changes were attempted. The lack of clear communication during this period made the situation even more challenging. Passengers were left uncertain about the cause of the delay, the expected timeline, and the next steps. This not only disrupted travel plans but also created unnecessary stress for everyone on board. I understand that operational issues can arise, but a malfunctioning jet bridge and the resulting extended delay suggest an area where procedures or equipment maintenance may need attention. I hope you will review this incident to prevent similar disruptions in the future. I would appreciate acknowledgment of this concern and consideration of appropriate compensation for the inconvenience and lost time caused by this delay. Thank you for taking the time to review my experience. I look forward to hearing from you. Sincerely, Dion Dillard

They made me pay $40 to check a bag that was listed as free when I bought my ticket. Then before boarding they offered to check any bags free.

It was a good trip. Flight Attendants were friendly and responsive.

Qatar airways ,boarding arrangements at Hamid international airport could been better

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

My seat tv didn’t work the whole trip. And the seat space is too small despite being seated at the front.

The seat cushions were very worn so they were extremely uncomfortable.

Delayed, no updates, had a rewards number but was not working

The seats from lax to DFW was so tight that I could not move my legs . No WiFi and had to pay . Not a good selection of entertainment

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports