TYS - FSD

$188 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
Travelers love KAYAK
41 299 237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$305
Typical prices: $399-$357
American Airlines
Tue 5/19Tue 5/26
TYS - FSD • 1 stop
Cheapest one-way
$188
Allegiant Air
Sat 5/23
TYS - FSD • 1 stop
Top airlines
Cheapest • from $305 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $399 (round-trip)
Shortest trip • 5h 09m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 35% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Tue, May 19 - Tue, May 26
American Airlines Logo
4:09 pm - 9:54 pm
TYS
-
FSD
6h 45m
1 stop
American Airlines Logo
5:35 pm - 11:56 pm
FSD
-
TYS
5h 21m
1 stop
$305American Airlines
Tue, May 19 - Tue, May 26
American Airlines Logo
5:00 am - 12:56 pm
TYS
-
FSD
8h 56m
2 stops
American Airlines Logo
5:35 pm - 11:56 pm
FSD
-
TYS
5h 21m
1 stop
$350American Airlines
Thu, Oct 15 - Tue, Oct 20
Delta Logo
6:15 pm - 10:51 pm
TYS
-
FSD
5h 36m
1 stop
Delta Logo
5:25 am - 11:06 am
FSD
-
TYS
4h 41m
1 stop
$357Delta
Thu, Oct 15 - Tue, Oct 20
Delta Logo
6:15 pm - 10:51 pm
TYS
-
FSD
5h 36m
1 stop
Delta Logo
5:25 am - 11:06 am
FSD
-
TYS
4h 41m
1 stop
$364Delta
Wed, Sep 16 - Sun, Sep 20
American Airlines Logo
6:00 am - 11:46 am
TYS
-
FSD
6h 46m
1 stop
American Airlines Logo
7:19 am - 12:31 pm
FSD
-
TYS
4h 12m
1 stop
$374American Airlines
Wed, Sep 16 - Sun, Sep 20
American Airlines Logo
7:15 am - 5:22 pm
TYS
-
FSD
11h 07m
2 stops
American Airlines Logo
7:19 am - 12:31 pm
FSD
-
TYS
4h 12m
1 stop
$391American Airlines
Thu, Oct 15 - Tue, Oct 20
American Airlines Logo
1:23 pm - 4:40 pm
TYS
-
FSD
4h 17m
1 stop
American Airlines Logo
12:31 pm - 11:30 pm
FSD
-
TYS
9h 59m
2 stops
$394American Airlines
Wed, Jun 3 - Thu, Jun 11
Allegiant Air Logo
2:19 pm - 6:01 pm
TYS
-
FSD
28h 42m
1 stop
Allegiant Air Logo
6:51 pm - 9:13 pm
FSD
-
TYS
25h 22m
1 stop
$404Allegiant Air
Thu, Oct 15 - Tue, Oct 20
Delta Logo
6:15 pm - 10:51 pm
TYS
-
FSD
5h 36m
1 stop
Delta Logo
5:15 am - 3:05 pm
FSD
-
TYS
8h 50m
2 stops
$419Delta
Wed, Sep 16 - Sun, Sep 20
Delta Logo
11:30 am - 10:09 pm
TYS
-
FSD
11h 39m
2 stops
Delta Logo
5:15 am - 3:07 pm
FSD
-
TYS
8h 52m
2 stops
$424Delta
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Sioux Falls?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Sioux Falls departing in May.

What is the cheapest month to fly from Knoxville to Sioux Falls?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Sioux Falls, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Sioux Falls is February, where tickets cost $269 (return) on average. On the other hand, the most expensive months are September and July, where the average cost of round-trip tickets is $570 and $517 respectively.

Good to know

Low seasonFebruary
Cheapest flight$188
Best time to beat the crowds with an average 35% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $188 for a one-way ticket and $305 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $434 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9637 reviews
8.1Crew
7.3Comfort
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

2.0 MediocreOmar, Apr 2026
HNL - DEN
Read more United Airlines reviews

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

boarded early to only find out that flight would sit at gate for 45 min to an hour. Landed in chicago and sat on runway for over an hour before got to gate. Total delay was extensive for a 45 min flight door to door.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

The flight was significantly delayed. The inbound flight from EWR was delayed departing because of mechanical problems. My original departure from CLT was 5:28 pm but due to the delay of the inbound flight, after arrival, deplaning, cleaning, boarding, we did not push back from the gate until 9:00 pm. Once in the air, the flight was smooth and what was originally supposed to be an arrival in ORD at 7:30 pm local time turned out to be 9:35 pm.

My bags were misplaced!!! Im in a foreign country with no bags

The entertainment options on the seat back video boards were nice.

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports