TYS - FSD

$329 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Tue, Sep 9 - Sat, Sep 13
United Airlines Logo
4:40 pm - 11:40 pmTYS-FSD
8h 00m1 stop
United Airlines Logo
3:12 pm - 10:45 pmFSD-TYS
6h 33m1 stop
$329United Airlines
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Tue, Sep 9 - Sat, Sep 13
United Airlines Logo
12:00 pm - 10:12 pmTYS-FSD
11h 12m2 stops
United Airlines Logo
6:00 am - 2:50 pmFSD-TYS
7h 50m1 stop
$359United Airlines
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Tue, Sep 9 - Sat, Sep 13
United Airlines Logo
12:00 pm - 10:12 pmTYS-FSD
11h 12m2 stops
United Airlines Logo
8:00 am - 7:53 pmFSD-TYS
10h 53m2 stops
$389United Airlines
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Fri, Oct 17 - Wed, Oct 22
Delta Logo
6:04 pm - 10:57 pmTYS-FSD
5h 53m1 stop
Delta Logo
5:20 am - 2:43 pmFSD-TYS
8h 23m2 stops
$413Delta
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Fri, Oct 17 - Wed, Oct 22
American Airlines Logo
5:37 pm - 12:01 pmTYS-FSD
19h 24m1 stop
American Airlines Logo
12:31 pm - 9:03 pmFSD-TYS
7h 32m1 stop
$459American Airlines
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Tue, Nov 25 - Sun, Nov 30
Allegiant Air Logo
6:30 am - 6:19 pmTYS-FSD
12h 49m1 stop
Allegiant Air Logo
10:33 am - 10:39 amFSD-TYS
23h 06m1 stop
$482Allegiant Air
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Fri, Oct 17 - Wed, Oct 22
American Airlines Logo
2:21 pm - 9:15 pmTYS-FSD
7h 54m1 stop
American Airlines Logo
1:33 pm - 11:39 pmFSD-TYS
9h 06m2 stops
$486American Airlines
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Fri, Oct 17 - Wed, Oct 22
Delta Logo
6:04 pm - 10:57 pmTYS-FSD
5h 53m1 stop
Delta Logo
5:20 am - 2:43 pmFSD-TYS
8h 23m2 stops
$489Delta
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Fri, Oct 3 - Sun, Oct 5
American Airlines Logo
4:37 pm - 9:23 pmTYS-FSD
5h 46m1 stop
American Airlines Logo
5:19 pm - 11:51 pmFSD-TYS
5h 32m1 stop
$495American Airlines
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Tue, Nov 25 - Sun, Nov 30
Allegiant Air Logo
6:30 am - 6:19 pmTYS-FSD
12h 49m1 stop
Allegiant Air Logo
10:15 am - 5:50 pmFSD-TYS
30h 35m2 stops
$580Allegiant Air
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Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to Sioux Falls?

The average price of all round-trip flights from Knoxville to Sioux Falls clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Sioux Falls on a Friday and more expensive on a Thursday. On your return trip to Knoxville, you should consider flying back on a Saturday, and avoid Thursdays for better deals.

Find deals

Good to know

Cheapest flight$329
Most popular time to fly with an average 56% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $329 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.2Comfort
8.0Crew
6.9Entertainment
7.5Boarding
6.5Food
Airline reviews

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

2.0 MediocreAnonymous, Aug 2025DFW - SAN
Read more American Airlines reviews

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The AA staff person who checked our bags was curt and almost rude. The FA also seemed unhappy doing her job. Overall it was like riding the school bus back in grade school.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Ring in first class for an overnight flight, there was no blankets nor pillows for first class customers.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports

Knoxville (TYS)
Sioux Falls (FSD)

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