TYS - FSD

$249 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$249
American Airlines
Sat 12/6Wed 12/10
TYS - FSD • 1 stop
Cheapest one-way
$239
Delta
Wed 4/1
TYS - FSD • 1 stop
Top airlines
American Airlines
Cheapest • from $249 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
8:06 am - 1:32 pmTYS-FSD
6h 26m1 stop
American Airlines Logo
7:00 am - 12:44 pmFSD-TYS
4h 44m1 stop
$249American Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
10:59 am - 9:06 pmTYS-FSD
11h 07m2 stops
American Airlines Logo
7:00 am - 12:44 pmFSD-TYS
4h 44m1 stop
$254American Airlines
Find Deal
Wed, Apr 15 - Sat, Apr 18
Delta Logo
6:45 am - 12:28 pmTYS-FSD
6h 43m1 stop
Delta Logo
1:20 pm - 9:28 pmFSD-TYS
7h 08m2 stops
$265Delta
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Tue, Nov 25 - Fri, Nov 28
Frontier Logo
4:48 pm - 7:31 pmTYS-FSD
27h 43m1 stop
Frontier Logo
8:26 pm - 7:10 pmFSD-TYS
21h 44m1 stop
$268Frontier
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Tue, Apr 14 - Sat, Apr 18
Delta Logo
6:45 am - 12:28 pmTYS-FSD
6h 43m1 stop
Delta Logo
4:09 pm - 10:56 pmFSD-TYS
5h 47m1 stop
$314Delta
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Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
10:59 am - 6:49 pmTYS-FSD
8h 50m2 stops
American Airlines Logo
1:09 pm - 11:57 pmFSD-TYS
9h 48m2 stops
$326American Airlines
Find Deal
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
5:56 am - 12:19 pmTYS-FSD
7h 23m1 stop
American Airlines Logo
1:33 pm - 11:43 pmFSD-TYS
9h 10m2 stops
$335American Airlines
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Sat, Dec 20 - Sat, Jan 3
American Airlines Logo
5:08 pm - 10:16 amTYS-FSD
18h 08m1 stop
American Airlines Logo
7:10 pm - 10:50 amFSD-TYS
14h 40m1 stop
$367American Airlines
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Tue, Dec 30 - Wed, Jan 21
American Airlines Logo
4:29 pm - 9:17 pmTYS-FSD
5h 48m1 stop
American Airlines Logo
6:00 am - 12:46 pmFSD-TYS
5h 46m1 stop
$378American Airlines
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Tue, Nov 25 - Fri, Nov 28
American Airlines Logo
5:05 am - 1:13 pmTYS-FSD
9h 08m2 stops
American Airlines Logo
6:30 am - 3:37 pmFSD-TYS
8h 07m1 stop
$380American Airlines
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Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to Sioux Falls?

The average price of all round-trip flights from Knoxville to Sioux Falls clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Sioux Falls on a Friday and more expensive on a Thursday. On your return trip to Knoxville, you should consider flying back on a Saturday, and avoid Thursdays for better deals.

Find deals

Good to know

Cheapest flight$239
Most popular time to fly with an average 55% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $239 for a one-way ticket and $249 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    oneworld is the only airline alliance operating flights between Knoxville and Sioux Falls.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11050 reviews
8.0Crew
6.9Entertainment
7.2Comfort
7.5Boarding
6.4Food
Airline reviews

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

6.0 GoodAnonymous, Nov 2025DFW - CMH
Read more American Airlines reviews

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports

Knoxville (TYS)
Sioux Falls (FSD)