TYS - FSD

$143 Find Cheap Flights from Knoxville to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$258
Typical prices: $365-$323
Allegiant Air
Fri 5/8Mon 5/11
TYS - FSD • 1 stop
Cheapest one-way
$143
Allegiant Air
Fri 4/17
TYS - FSD • 1 stop
Top airlines
Cheapest • from $258 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Sioux Falls. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $399 (round-trip)
Shortest trip • 5h 09m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 32% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sioux Falls!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Sioux Falls (TYS-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Sioux Falls

Fri, May 8 - Mon, May 11
Allegiant Air Logo
7:30 am - 5:21 pm
TYS
-
FSD
10h 51m
1 stop
Allegiant Air Logo
10:45 am - 9:48 pm
FSD
-
TYS
10h 03m
1 stop
$258Allegiant Air
Fri, May 8 - Mon, May 11
Multiple Airlines Logo
7:30 am - 5:21 pm
TYS
-
FSD
10h 51m
1 stop
Multiple Airlines Logo
6:38 pm - 10:36 am
FSD
-
TYS
38h 58m
2 stops
$299Multiple Airlines
Fri, Apr 17 - Tue, Apr 21
United Airlines Logo
7:00 am - 10:42 am
TYS
-
FSD
4h 42m
1 stop
United Airlines Logo
6:00 am - 3:06 pm
FSD
-
TYS
8h 06m
1 stop
$339United Airlines
Fri, Apr 17 - Tue, Apr 21
Delta Logo
5:54 pm - 11:40 pm
TYS
-
FSD
6h 46m
1 stop
Delta Logo
1:44 pm - 11:54 pm
FSD
-
TYS
9h 10m
2 stops
$344Delta
Fri, Apr 17 - Tue, Apr 21
Delta Logo
4:38 pm - 11:02 pm
TYS
-
FSD
7h 24m
2 stops
Delta Logo
5:00 am - 4:42 pm
FSD
-
TYS
10h 42m
2 stops
$349Delta
Fri, May 8 - Mon, May 11
American Airlines Logo
2:06 pm - 9:54 pm
TYS
-
FSD
8h 48m
2 stops
American Airlines Logo
3:17 pm - 11:55 pm
FSD
-
TYS
7h 38m
2 stops
$425American Airlines
Fri, Jun 26 - Fri, Jul 3
Allegiant Air Logo
7:00 pm - 5:05 pm
TYS
-
FSD
23h 05m
1 stop
Allegiant Air Logo
11:41 am - 9:57 am
FSD
-
TYS
21h 16m
2 stops
$493Allegiant Air
Fri, Jun 26 - Fri, Jul 3
American Airlines Logo
6:43 pm - 11:30 am
TYS
-
FSD
17h 47m
1 stop
American Airlines Logo
5:34 pm - 11:52 pm
FSD
-
TYS
5h 18m
1 stop
$571American Airlines
Fri, Jun 26 - Fri, Jul 3
American Airlines Logo
5:00 am - 11:30 am
TYS
-
FSD
7h 30m
2 stops
American Airlines Logo
12:09 pm - 11:51 pm
FSD
-
TYS
10h 42m
2 stops
$852American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Sioux Falls flights

Get data-powered insights and trends into flights from Knoxville to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Sioux Falls?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Sioux Falls departing in May.

What is the cheapest month to fly from Knoxville to Sioux Falls?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Sioux Falls, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Sioux Falls is February, where tickets cost $269 (return) on average. On the other hand, the most expensive months are June and July, where the average cost of round-trip tickets is $643 and $517 respectively.

Good to know

Low seasonFebruary
Cheapest flight$143
Best time to beat the crowds with an average 32% drop in price.
Most popular time to fly with an average 63% increase in price.
Flight from Knoxville to Sioux Falls

When to book flights from Knoxville to Sioux Falls

Are your dates flexible? Find out the best times to travel from Knoxville to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Knoxville to Sioux Falls

  • What is the cheapest flight from Knoxville to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Knoxville to Sioux Falls was $143 for a one-way ticket and $258 for a round-trip.

  • Do I need a passport to fly between Knoxville and Sioux Falls?

    No

  • Which airports will I be using when flying from Knoxville to Sioux Falls?

    Knoxville and Sioux Falls are both served by 1 main airport. You will leave Knoxville from Knoxville McGhee Tyson and will be arriving at Sioux Falls Joe Foss Field.

  • Which aircraft models fly most regularly from Knoxville to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Sioux Falls?

    Star Alliance, and oneworld are the airline alliances operating flights between Knoxville and Sioux Falls, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Knoxville to Sioux Falls, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Knoxville to Sioux Falls are United Airlines and American Airlines. With an average price for the route of $408 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $401 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Knoxville to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Knoxville to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9533 reviews
7.1Entertainment
7.7Boarding
6.6Food
8.1Crew
7.3Comfort
Airline reviews

It was perfect! I've never flown with United before, but I definitely will in the future

10.0 ExcellentAnonymous, Apr 2026
SFO - LAS
Read more United Airlines reviews

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

Just a bad day to fly. Flight was delayed from scheduled 6:50 pm departure to 8:50 pm. Combination of factors mostly related to weather at the destination airport (which is where the incoming flight originated) which delayed the inbound flight over an hour. Once on board, we taxied but had to hold again on the taxiway for 10 minutes or so. We did not get wheels up until after 9 pm. The flight was smooth but about 18 minutes from our destination, we had to hold for several minutes more due to weather at ORD. We finally landed at ORD about 11:08 pm (accounting for the time difference, that was about a 3 hour delay from our scheduled departure time). It felt like we were never going to get to our destination. But the flight crew and attendants were very good. The movie selection onboard was also very nice. Got to watch half of a movie just during our taxi from the gate at ATL due to the delay!

Fine. The issues I had were associated with luggage being delayed from Turkey to Tanzania

No meal service to the back of the plane as it started late or was too slow to get it out before it was time to land.

Terrible, if possible won't be flying again anytime soon!

Efficient boarding and early departure. Very smooth flight. Early arrival in ATL. Great flight.

We purchase first class seats for the first time for multiples of standard economy ticket. There was no access to the club lounge and no priority boarding. The meal and the service once on the plane were superior and the seat was nicer, but not worth the price difference. I will be happy to seat in economy and spend the difference on more travel.

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

Smooth and easy boarding, comfortable for the entire 5 hour flight, and the seat back entertainment was great! I appreciated all the features, from location info and maps, movies, the ability to connect with Bluetooth headphones, and good selection of movies. Food was good, normal airline snacks (I didn’t purchase anything)

Early morning flight and no food in First Class except a "salmon" box. No thank you. Was informed before take off by Captain that the plane was not serviced before we boarded in Phoenix. How does that happen? Need more frequent additions/turn over on the Entertainment. Thanks

Moved to earlier flight which unexpectedly had maintenance issues initially indicated as quick fix to ultimately plane changes. Moved back to original flight, also delayed. In all cases customer updates and communication very unclear, no updates on drivers for delays.

Flight was delayed. No urgency by American Airlines team to assist those with connecting flights. It was basically you are on your own to run through the terminals to try and make your connection. Thanks, Mary

I have never been assaulted they way I was today in Charlotte - shame on American

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

Better snacks but flight and crew were amazing on this flight

Found that the plane used for this short flight is smaller and therefore the seats are really squeezed tight.

It was the most un-special flight experience in my life.

Plane was super cold. No entertainment unless you were with mileage program Getting off the plane was super slow

Flight was on-time, boarding was flawless and the crew was friendly.

Everything you need to know for your flight from Knoxville to Sioux Falls

Information on your arrival and departure airports