FSD - TYS

$284 Find Cheap Flights from Sioux Falls to Knoxville - Compare and Save

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Everything you should know

Cheapest round-trip
$315
Typical prices: $321-$484
American Airlines
Sat 12/29Fri 1/5
FSD - TYS • 1 stop
Cheapest one-way
$284
Typical prices: $351-$415
Delta
Sat 11/24
FSD - TYS • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Sioux Falls and Knoxville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 37% price drop
September
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $362 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 5h 16m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Sioux Falls to Knoxville (FSD-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to Knoxville

Tue, Dec 29 - Tue, Jan 5
American Airlines Logo
6:00 am - 2:05 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
7h 05m1 stop Dallas/Fort Worth
American Airlines Logo
5:30 am - 11:47 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
7h 17m1 stop Dallas/Fort Worth
$315American Airlines
Sat, Oct 31 - Tue, Nov 3
American Airlines Logo
12:18 pm - 6:20 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
5h 02m1 stop Chicago O'Hare Intl
American Airlines Logo
8:52 pm - 12:29 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 37m1 stop Chicago O'Hare Intl
$322American Airlines
Sat, Oct 31 - Tue, Nov 3
American Airlines Logo
6:20 am - 2:07 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 47m1 stop Dallas/Fort Worth
American Airlines Logo
2:13 pm - 12:29 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
11h 16m2 stops Charlotte Douglas Chicago O'Hare Intl
$327American Airlines
Sat, Jan 9 - Wed, Jan 13
United Airlines Logo
10:00 am - 5:03 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 03m1 stop Chicago O'Hare Intl
United Airlines Logo
6:40 am - 10:40 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
5h 00m1 stop Chicago O'Hare Intl
$395United Airlines
Sat, Jan 9 - Wed, Jan 13
United Airlines Logo
10:00 am - 5:03 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 03m1 stop Chicago O'Hare Intl
United Airlines Logo
10:45 am - 8:46 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
11h 01m2 stops Chicago O'Hare Intl Denver Intl
$400United Airlines
Thu, Nov 19 - Wed, Nov 25
Delta Logo
8:31 am - 4:20 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 49m1 stop Minneapolis St Paul
Delta Logo
4:00 pm - 7:56 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
4h 56m1 stop Atlanta Hartsfield-Jackson
$406Delta
Sat, Jan 9 - Wed, Jan 13
United Airlines Logo
10:00 am - 5:03 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
6h 03m1 stop Chicago O'Hare Intl
United Airlines Logo
6:40 am - 10:40 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
5h 00m1 stop Chicago O'Hare Intl
$415United Airlines
Fri, Oct 23 - Sun, Oct 25
Allegiant Air Logo
9:59 am - 8:51 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
9h 52m1 stop Tampa St. Petersburg
Allegiant Air Logo
7:00 am - 6:44 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
12h 44m1 stop Orlando Sanford Intl
$491Allegiant Air
Sun, Sep 27 - Thu, Oct 1
Allegiant Air Logo
10:02 pm - 3:28 pmFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
16h 26m1 stop Las Vegas Harry Reid Intl
Allegiant Air Logo
8:28 am - 9:19 amTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
25h 51m1 stop Tampa St. Petersburg
$533Allegiant Air
Sat, Mar 13 - Fri, Mar 19
Delta Logo
5:25 am - 11:06 amFSD  Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson
4h 41m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:55 am - 12:11 pmTYS  Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field
5h 16m1 stop Minneapolis St Paul
$599Delta
Booking Insights

Price, demand and travel trends for Sioux Falls to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Sioux Falls to Knoxville with more confidence.

How much is a round-trip flight from Sioux Falls to Knoxville?

Round-trip flights from Sioux Falls to Knoxville start at $315. Prices are below average for this route right now, with typical round-trip fares ranging from $321 to $484. The lowest price found in the past 5 days was $315 on American Airlines.

What's the cheapest day of the week to fly from Sioux Falls to Knoxville?

Wednesday is the cheapest day of the week to fly from Sioux Falls to Knoxville, it is 31% cheaper than the average day. Friday is the most expensive day with flight prices 38% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Sioux Falls to Knoxville?

  • October is the cheapest month to fly from Sioux Falls to Knoxville at $277 round-trip.
  • March ($593) and July ($568) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 114% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Sioux Falls to Knoxville flights

Low season

February

Cheapest flight

$284
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Sioux Falls to Knoxville

When to book flights from Sioux Falls to Knoxville

Are your dates flexible? Find out the best times to travel from Sioux Falls to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Sioux Falls to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Sioux Falls to Knoxville?

    Flights from Sioux Falls to Knoxville usually depart from Sioux Falls Joe Foss Field (FSD) and arrive at Knoxville McGhee Tyson (TYS).

  • What cabin classes can I book on flights from Sioux Falls to Knoxville?

    Only Economy Class is available on flights from Sioux Falls to Knoxville.

  • Which airports do connecting flights from Sioux Falls to Knoxville pass through?

    One-stop flights from Sioux Falls to Knoxville most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 45% of one-stop connections
    • Dallas/Fort Worth (DFW) - 32% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections
    • Minneapolis St Paul (MSP) - 5% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Sioux Falls to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 50% on the Sioux Falls to Knoxville route. Wednesday is the cheapest departure day at $304 round-trip on average, while Friday is the most expensive at $604, a difference of $300. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Sioux Falls to Knoxville?

    A nonstop flight from Sioux Falls to Knoxville takes 0h 00m, covering 863 miles.

  • Do I need a passport to fly from Sioux Falls to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Sioux Falls to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $315 to $1,794. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Sioux Falls to Knoxville looking right now?

    One-way fares from Sioux Falls to Knoxville are currently higher than usual. Average one-way flight prices are about $467, which is 22% above the typical average for this route.

  • How much time can I save by choosing a different layover airport from Sioux Falls to Knoxville?

    Flying via Chicago O'Hare Intl (ORD) gives the shortest average 1-stop total travel time at 5h 16m, compared with 5h 27m via Atlanta Hartsfield-Jackson (ATL) and 5h 42m via Minneapolis St Paul (MSP).

  • What is the time difference between Sioux Falls and Knoxville?

    Knoxville is 1 hour ahead of Sioux Falls (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a Sioux Falls to Knoxville flight?

    Round-trip flights from Sioux Falls to Knoxville range from $321 to $484, with an average of $436 over the past 12 months. Anything below $321 counts as a good deal.

Your guide to booking Sioux Falls to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average $304 - about $300 less than Friday (50% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Sioux Falls to Knoxville trip for October. Fares historically average $277 round-trip in that month - typically $316 less than the most expensive month, which is March (based on the last 12 months).

More options for your flight from Sioux Falls to Knoxville

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