FSD - TYS

$158 Find Cheap Flights from Sioux Falls to Knoxville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to Knoxville departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$315
Typical prices: $334-$387
American Airlines
Sat 9/26Sat 10/3
FSD - TYS • 1 stop
Cheapest one-way
$158
Delta
Fri 9/11
FSD - TYS • 1 stop
Top airlines
Cheapest • from $317 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Sioux Falls and Knoxville. You'll need at least 1 connection.
Insights
Insights
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Insights
Top layover airports
Cheapest • Avg $362 (round-trip)
Shortest trip • 4h 45m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 34% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Sioux Falls to Knoxville (FSD-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to Knoxville

Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:00 am - 2:29 pm
FSD
-
TYS
7h 29m
1 stop
American Airlines Logo
8:15 pm - 12:29 am
TYS
-
FSD
5h 14m
1 stop
$315American Airlines
Wed, Sep 30 - Sat, Oct 3
American Airlines Logo
6:00 am - 1:53 pm
FSD
-
TYS
6h 53m
1 stop
American Airlines Logo
8:15 pm - 12:29 am
TYS
-
FSD
5h 14m
1 stop
$315American Airlines
Wed, Aug 26 - Wed, Sep 2
American Airlines Logo
5:23 pm - 11:46 pm
FSD
-
TYS
5h 23m
1 stop
American Airlines Logo
6:03 am - 12:17 pm
TYS
-
FSD
7h 14m
1 stop
$317American Airlines
Wed, Aug 26 - Wed, Sep 2
American Airlines Logo
6:24 am - 12:51 pm
FSD
-
TYS
5h 27m
1 stop
American Airlines Logo
7:34 am - 11:36 am
TYS
-
FSD
5h 02m
1 stop
$317American Airlines
Wed, Oct 21 - Sat, Oct 24
Multiple Airlines Logo
7:31 pm - 1:11 pm
FSD
-
TYS
16h 40m
1 stop
Multiple Airlines Logo
4:50 pm - 6:44 pm
TYS
-
FSD
26h 54m
1 stop
$325Multiple Airlines
Thu, Aug 13 - Mon, Aug 17
Multiple Airlines Logo
7:10 pm - 8:18 pm
FSD
-
TYS
24h 08m
1 stop
Multiple Airlines Logo
6:30 am - 7:23 pm
TYS
-
FSD
13h 53m
2 stops
$330Multiple Airlines
Sat, Sep 26 - Thu, Oct 1
Delta Logo
4:28 pm - 11:14 pm
FSD
-
TYS
5h 46m
1 stop
Delta Logo
2:08 pm - 7:47 pm
TYS
-
FSD
6h 39m
1 stop
$334Delta
Tue, Dec 29 - Tue, Jan 5
Delta Logo
5:25 am - 11:06 am
FSD
-
TYS
4h 41m
1 stop
Delta Logo
5:57 pm - 10:12 pm
TYS
-
FSD
5h 15m
1 stop
$362Delta
Fri, Oct 16 - Thu, Oct 22
Multiple Airlines Logo
7:31 pm - 5:04 pm
FSD
-
TYS
44h 33m
2 stops
Multiple Airlines Logo
9:29 pm - 11:16 am
TYS
-
FSD
14h 47m
1 stop
$363Multiple Airlines
Mon, Sep 14 - Sat, Sep 19
Delta Logo
5:30 am - 11:18 am
FSD
-
TYS
4h 48m
1 stop
Delta Logo
1:31 pm - 7:47 pm
TYS
-
FSD
7h 16m
1 stop
$409Delta
Booking Insights

KAYAK's insights & trends for Sioux Falls to Knoxville flights

Get data-powered insights and trends into flights from Sioux Falls to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Sioux Falls to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Sioux Falls to Knoxville departing in August.

Flight prices are below average for this route right now.

Flights to Knoxville from Sioux Falls usually cost between $323 and $595 in August.
The lowest price found in the past 5 days was $317 on American Airlines (Aug 26-Sep 2).

What is the cheapest month to fly from Sioux Falls to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Sioux Falls to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Sioux Falls to Knoxville is October, where tickets cost $277 (return) on average. On the other hand, the most expensive months are March and July, where the average cost of round-trip tickets is $593 and $567 respectively.

Good to know

Low season

February

Cheapest flight

$158
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Sioux Falls to Knoxville

When to book flights from Sioux Falls to Knoxville

Are your dates flexible? Find out the best times to travel from Sioux Falls to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Sioux Falls to Knoxville

  • What is the cheapest flight from Sioux Falls to Knoxville?

    In the last 5 days, the lowest price for a flight from Sioux Falls to Knoxville was $158 for a one-way ticket and $317 for a round-trip.

  • Do I need a passport to fly between Sioux Falls and Knoxville?

    No, a passport isn't needed to fly from Sioux Falls to Knoxville. However, local authorities might ask for an official ID.

  • Which airports will I be using when flying from Sioux Falls to Knoxville?

    Sioux Falls and Knoxville are both served by 1 main airport. You will leave Sioux Falls from Sioux Falls Joe Foss Field and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Sioux Falls to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Sioux Falls to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Sioux Falls and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Sioux Falls to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Sioux Falls to Knoxville are Delta and American Airlines. With an average price for the route of $418 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $354 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Sioux Falls to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Sioux Falls is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Sioux Falls with another airline. Booking your flights between Sioux Falls and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Sioux Falls up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Sioux Falls to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8497 reviews
8.1Boarding
8.5Crew
7.8Comfort
7.8Entertainment
7.2Food
Airline reviews

Internet didn’t work for this leg either. The seat was fine but didn’t have seatback screen, which I knew when I booked it. The biggest letdown is Deltas new policy on beverage/snack service not being served for flights less than 350 miles. I know this is a cost cutting measure, but how much does it really cost to give a drink and a snack for inflated airfare? I really am surprised that with Delta Comfort they don’t provide beverage/snack service given these seats cost extra to purchase. Really need to reconsider this, even if it’s for the Delta Comfort and above.

6.0 GoodLane, Jul 2026
ATL - MEM
Read more Delta reviews

Internet didn’t work for this leg either. The seat was fine but didn’t have seatback screen, which I knew when I booked it. The biggest letdown is Deltas new policy on beverage/snack service not being served for flights less than 350 miles. I know this is a cost cutting measure, but how much does it really cost to give a drink and a snack for inflated airfare? I really am surprised that with Delta Comfort they don’t provide beverage/snack service given these seats cost extra to purchase. Really need to reconsider this, even if it’s for the Delta Comfort and above.

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

Should never have had to go to Detroit from Orlando back to Tennessee!

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

Smallest leg room I've ever had on a plane.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Kind staff. Snacks are small but that’s the new normal.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

Flight was great. DELTA did a fantastic job! ATL was busy, as usual!

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

technology worked well and everything ran smoothly. The seats are quite cramped so please don't try to re-engineer the cabin to squeeze more bodies on board.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

At least it was a short flight. Greyhound with wings.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Our flight got changed and/or delayed 8 times before we boarded.

Everything you need to know for your flight from Sioux Falls to Knoxville

Information on your arrival and departure airports