$436 Find Cheap Flights from La Crosse to South Carolina

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from La Crosse to South Carolina departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to South Carolina, as well as popular online travel agencies
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Cheap Flights from La Crosse to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$490
Charlotte
Charlotte1 stop$318
Charleston
Charleston1 stop$490
Charlotte
Charlotte1 stop$318

Book Cheap La Crosse to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from La Crosse to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from La Crosse to South Carolina

Sat, May 9 - Tue, May 12
American Airlines Logo
5:40 am - 9:55 pm
LSE
-
CLT
15h 15m
1 stop
American Airlines Logo
2:04 pm - 11:54 pm
CLT
-
LSE
10h 50m
1 stop
$318American Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
11:35 am - 10:15 pm
LSE
-
SAV
9h 40m
2 stops
American Airlines Logo
5:40 am - 9:35 am
SAV
-
LSE
4h 55m
1 stop
$436American Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
5:09 am - 10:48 pm
LSE
-
SAV
16h 39m
1 stop
American Airlines Logo
5:40 am - 11:54 pm
SAV
-
LSE
19h 14m
1 stop
$440American Airlines
Sat, May 9 - Tue, May 12
United Airlines Logo
6:00 am - 6:55 pm
LSE
-
CLT
11h 55m
2 stops
United Airlines Logo
10:34 am - 8:59 am
CLT
-
LSE
23h 25m
1 stop
$454United Airlines
Sat, May 9 - Tue, May 12
United Airlines Logo
6:00 am - 6:55 pm
LSE
-
CLT
11h 55m
2 stops
United Airlines Logo
7:43 pm - 8:59 am
CLT
-
LSE
14h 16m
2 stops
$459United Airlines
Fri, Apr 3 - Mon, Apr 6
American Airlines Logo
6:29 pm - 10:18 am
LSE
-
CLT
14h 49m
1 stop
American Airlines Logo
10:48 pm - 9:35 am
CLT
-
LSE
11h 47m
1 stop
$488American Airlines
Wed, Mar 11 - Sat, Mar 14
American Airlines Logo
5:09 am - 11:34 am
LSE
-
CHS
5h 25m
1 stop
American Airlines Logo
7:10 am - 11:02 am
CHS
-
LSE
4h 52m
1 stop
$490American Airlines
Thu, Apr 2 - Mon, Apr 6
American Airlines Logo
11:34 am - 11:59 pm
LSE
-
SAV
11h 25m
2 stops
American Airlines Logo
5:20 pm - 11:36 pm
SAV
-
LSE
7h 16m
1 stop
$490American Airlines
Thu, May 7 - Sun, May 10
American Airlines Logo
10:05 am - 11:06 pm
LSE
-
CHS
12h 01m
1 stop
American Airlines Logo
7:07 am - 11:54 pm
CHS
-
LSE
17h 47m
1 stop
$491American Airlines
Sat, Mar 14 - Wed, Mar 18
American Airlines Logo
5:09 am - 11:07 am
LSE
-
CLT
4h 58m
1 stop
American Airlines Logo
6:00 am - 11:01 am
CLT
-
LSE
6h 01m
1 stop
$492American Airlines
Booking Insights

KAYAK's insights & trends for La Crosse to South Carolina flights

Get data-powered insights and trends into flights from La Crosse to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How long does a flight from La Crosse to South Carolina take?

The duration of a flight to South Carolina depends on your arrival airport. The shortest routes to South Carolina from La Crosse are to Charleston, which takes 5h 25m, and Greenville, which takes 16h 19m.

Good to know

Cheapest flight$318
Flight from La Crosse to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from La Crosse to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from La Crosse to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from La Crosse to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from La Crosse to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from La Crosse to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from La Crosse to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from La Crosse to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from La Crosse to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from La Crosse to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from La Crosse to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from La Crosse to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11367 reviews
7.5Boarding
6.4Food
7.2Comfort
6.9Entertainment
8.0Crew
Airline reviews

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

2.0 MediocreJames, Feb 2026
DFW - MCO
Read more American Airlines reviews

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

It was good experience this time. The flight was on time.

I very rarely fly American and my experience today reenforces that is the correct decision. While the staff were all very courteous, our flight was first thing in the morning so there was no reason to be delayed, yet appropriate maintenance checks weren’t completed prior to our flight so we were delayed multiple times. Not a great showing, American Airlines.

It's very confusing because Kayak has it as American Airlines, but it was Hawaiian Airlines, but operated by Alaska Airlines. I had to go to the airport for my boarding pass because American said I didn't have any trips.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Everything you need to know for your flight from La Crosse to South Carolina

Information on your arrival and departure airports