$108 Find Cheap Flights from La Crosse to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from La Crosse to South Carolina departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from La Crosse to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from La Crosse to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston2 stops$348
Charlotte
Charlotte1 stop$342
Charleston
Charleston2 stops$348
Charlotte
Charlotte1 stop$342

Book Cheap La Crosse to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from La Crosse to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from La Crosse to South Carolina

Tue, Jun 16 - Sat, Jun 20
American Airlines Logo
11:52 am - 8:05 pm
LSE
-
CLT
7h 13m
1 stop
American Airlines Logo
7:44 am - 11:07 am
CLT
-
LSE
4h 23m
1 stop
$342American Airlines
Tue, Jun 16 - Sat, Jun 20
American Airlines Logo
11:52 am - 11:47 pm
LSE
-
CHS
10h 55m
2 stops
American Airlines Logo
7:24 am - 11:07 am
CHS
-
LSE
4h 43m
1 stop
$348American Airlines
Tue, Jun 16 - Sat, Jun 20
American Airlines Logo
11:52 am - 9:53 pm
LSE
-
CHS
9h 01m
2 stops
American Airlines Logo
1:35 pm - 12:19 am
CHS
-
LSE
11h 44m
2 stops
$353American Airlines
Tue, Sep 15 - Sun, Sep 20
American Airlines Logo
12:26 pm - 9:56 pm
LSE
-
SAV
8h 30m
2 stops
American Airlines Logo
7:00 am - 4:52 pm
SAV
-
LSE
10h 52m
2 stops
$411American Airlines
Wed, Jun 24 - Sun, Jun 28
American Airlines Logo
5:25 pm - 11:58 pm
LSE
-
CLT
5h 33m
1 stop
American Airlines Logo
7:44 am - 11:22 am
CLT
-
LSE
4h 38m
1 stop
$436American Airlines
Thu, Nov 19 - Sun, Nov 22
American Airlines Logo
9:50 am - 5:15 pm
LSE
-
CLT
6h 25m
1 stop
American Airlines Logo
11:31 am - 5:32 pm
CLT
-
LSE
7h 01m
1 stop
$440American Airlines
Sat, Jun 13 - Thu, Jun 18
American Airlines Logo
11:37 am - 11:59 pm
LSE
-
CHS
11h 22m
2 stops
American Airlines Logo
7:29 am - 11:22 am
CHS
-
LSE
4h 53m
1 stop
$442American Airlines
Tue, Sep 15 - Sun, Sep 20
American Airlines Logo
12:26 pm - 9:56 pm
LSE
-
SAV
8h 30m
2 stops
American Airlines Logo
7:00 am - 4:52 pm
SAV
-
LSE
10h 52m
2 stops
$447American Airlines
Sat, Jun 13 - Thu, Jun 18
American Airlines Logo
11:37 am - 7:22 pm
LSE
-
CHS
6h 45m
1 stop
American Airlines Logo
7:29 am - 11:22 am
CHS
-
LSE
4h 53m
1 stop
$472American Airlines
Tue, Sep 15 - Sun, Sep 20
American Airlines Logo
12:26 pm - 9:56 pm
LSE
-
SAV
8h 30m
2 stops
American Airlines Logo
7:00 am - 4:52 pm
SAV
-
LSE
10h 52m
2 stops
$483American Airlines
Booking Insights

KAYAK's insights & trends for La Crosse to South Carolina flights

Get data-powered insights and trends into flights from La Crosse to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How long does a flight from La Crosse to South Carolina take?

The duration of a flight to South Carolina depends on your arrival airport. The shortest routes to South Carolina from La Crosse are to Charleston, which takes 4h 56m, and Greenville, which takes 5h 25m.

Find deals

Good to know

Cheapest flight$108
Flight from La Crosse to Greenville

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from La Crosse to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from La Crosse to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from La Crosse to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from La Crosse to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from La Crosse to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from La Crosse to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from La Crosse to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from La Crosse to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from La Crosse to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from La Crosse to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from La Crosse to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11639 reviews
7.2Comfort
6.4Food
7.5Boarding
7.9Crew
6.9Entertainment
Airline reviews

The flight from LA to Chicago was smooth and service was very good overall.

8.0 ExcellentAnonymous, Jun 2026
LAX - ORD
Read more American Airlines reviews

The flight from LA to Chicago was smooth and service was very good overall.

The flight from Dallas to Tokyo was not on Japan Airlines. It was on American Airlines. Very disappointed that we did not fly on Japan Airlines. Will not be using you liars again. I’ll just book direct from the airline next time. Wish you could make this right and has us fly on Japan Air when heading back home to the US.

The Mario was so helpful and provided amazing customer service however l have being waiting for a callback for almost a week now and have not heard anything further after l informed them l wanted to change my date of traveling because of my hospital appointment even send them proof and l was unable to use manag your booking on their website is a bit frustrating and l would appreciate an update on My request as soon as possible. And have called them times without numbers no response

They made nearly everyone check their bag because the overhead bins are way too small. Extremely inconvenient

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Everything you need to know for your flight from La Crosse to South Carolina

Information on your arrival and departure airports

La Crosse (LSE)