Which airports can I use when flying from La Crosse to Greenville?

Flights from La Crosse to Greenville usually depart from La Crosse (LSE) and arrive at Greenville (GSP).

What cabin classes can I book on flights from La Crosse to Greenville?

Only Economy Class is available on flights from La Crosse to Greenville.

Which airports do connecting flights from La Crosse to Greenville pass through?

Most connecting flights from La Crosse to Greenville pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from La Crosse to Greenville?

Yes. Being flexible with your travel dates can save you up to 18% on the La Crosse to Greenville route. Thursday is the cheapest departure day at $360 round-trip on average, while Tuesday is the most expensive at $437, a difference of $77. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Do I need a passport to fly from La Crosse to Greenville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from La Crosse to Greenville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $493 to $1,221. That means the highest observed fare was about 2x higher than the lowest one.

What is the time difference between La Crosse and Greenville?

Greenville is 1 hour ahead of La Crosse (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Greenville Airport (GSP)?

Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include: · Budget · Alamo · Thrifty · Enterprise Rent-A-Car · Avis

How much should I expect to pay for a La Crosse to Greenville flight?

Round-trip flights from La Crosse to Greenville range from $360 to $437, with an average of $367 over the past 12 months. Anything below $360 counts as a good deal.

What is the cheapest airline to fly from La Crosse to Greenville?

American Airlines ($493) offered the cheapest round-trip ticket from La Crosse to Greenville in the last 5 days.

What is the cheapest layover airport when flying from La Crosse to Greenville?

Flights via Chicago O'Hare Intl (ORD) offer the most affordable fares, with an average round-trip price of $386. Based on KAYAK data over the past 3 months.

When flying from La Crosse to Greenville which airport offers the shortest layover?

Chicago O'Hare Intl (ORD) had the shortest average connection time for La Crosse to Greenville layovers at 182 minutes over the past 3 months.

$493 CHEAP FLIGHTS from La Crosse to Greenville (LSE - GSP)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$493

Typical prices: $360-$437

American Airlines

Tue 10/30Sun 11/4

LSE - GSP • 2 stops

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Greenville!

Flight Deals

Cheap Flights from La Crosse to Greenville (LSE-GSP)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from La Crosse to Greenville

Fri, Oct 30 - Wed, Nov 4

12:23 pm - 10:52 pmLSE La Crosse-GSP Greenville

9h 29m2 stops Chicago O'Hare Intl Miami

7:02 am - 11:53 amGSP Greenville-LSE La Crosse

5h 51m1 stop Chicago O'Hare Intl

$493American Airlines

Fri, Oct 30 - Wed, Nov 4

12:23 pm - 10:52 pmLSE La Crosse-GSP Greenville

9h 29m2 stops Chicago O'Hare Intl Miami

3:35 pm - 12:18 amGSP Greenville-LSE La Crosse

9h 43m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$498American Airlines

Fri, Oct 30 - Wed, Nov 4

6:55 pm - 6:08 pmLSE La Crosse-GSP Greenville

22h 13m1 stop Chicago O'Hare Intl

7:02 am - 11:53 amGSP Greenville-LSE La Crosse

5h 51m1 stop Chicago O'Hare Intl

$517American Airlines

Fri, Oct 30 - Mon, Nov 2

6:55 pm - 11:08 amLSE La Crosse-GSP Greenville

15h 13m1 stop Chicago O'Hare Intl

6:42 pm - 11:53 amGSP Greenville-LSE La Crosse

18h 11m1 stop Chicago O'Hare Intl

$526American Airlines

Fri, Oct 30 - Mon, Nov 2

12:23 pm - 10:39 pmLSE La Crosse-GSP Greenville

9h 16m2 stops Chicago O'Hare Intl New York LaGuardia

6:42 pm - 12:18 amGSP Greenville-LSE La Crosse

6h 36m1 stop Chicago O'Hare Intl

$568American Airlines

Fri, Oct 30 - Mon, Nov 2

12:23 pm - 10:05 pmLSE La Crosse-GSP Greenville

8h 42m2 stops Chicago O'Hare Intl Dallas/Fort Worth

3:35 pm - 12:18 amGSP Greenville-LSE La Crosse

9h 43m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$573American Airlines

Mon, Sep 14 - Fri, Sep 18

5:22 pm - 11:03 amLSE La Crosse-GSP Greenville

16h 41m1 stop Chicago O'Hare Intl

7:24 am - 12:20 amGSP Greenville-LSE La Crosse

17h 56m1 stop Chicago O'Hare Intl

$1,162American Airlines

Mon, Sep 14 - Fri, Sep 18

5:22 pm - 11:03 amLSE La Crosse-GSP Greenville

16h 41m1 stop Chicago O'Hare Intl

6:12 am - 4:52 pmGSP Greenville-LSE La Crosse

11h 40m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$1,192American Airlines

Mon, Sep 14 - Fri, Sep 18

12:02 pm - 10:48 pmLSE La Crosse-GSP Greenville

9h 46m2 stops Chicago O'Hare Intl New York LaGuardia

6:12 am - 4:52 pmGSP Greenville-LSE La Crosse

11h 40m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$1,221American Airlines

Booking Insights

Price, demand and travel trends for La Crosse to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from La Crosse to Greenville with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from La Crosse to Greenville?

Round-trip flights from La Crosse to Greenville start at $493. Prices are above average for this route right now, with typical round-trip fares ranging from $360 to $437. The lowest price found in the past 5 days was $493 on American Airlines.

Find deals

Cheapest flight	$493

Flight from La Crosse to Greenville

When to book flights from La Crosse to Greenville

Are your dates flexible? Find out the best times to travel from La Crosse to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from La Crosse to Greenville?
Flights from La Crosse to Greenville usually depart from La Crosse (LSE) and arrive at Greenville (GSP).
What cabin classes can I book on flights from La Crosse to Greenville?
Only Economy Class is available on flights from La Crosse to Greenville.
Which airports do connecting flights from La Crosse to Greenville pass through?
Most connecting flights from La Crosse to Greenville pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from La Crosse to Greenville?
Yes. Being flexible with your travel dates can save you up to 18% on the La Crosse to Greenville route. Thursday is the cheapest departure day at $360 round-trip on average, while Tuesday is the most expensive at $437, a difference of $77. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
Do I need a passport to fly from La Crosse to Greenville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from La Crosse to Greenville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $493 to $1,221. That means the highest observed fare was about 2x higher than the lowest one.
What is the time difference between La Crosse and Greenville?
Greenville is 1 hour ahead of La Crosse (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Greenville Airport (GSP)?
Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include:
· Budget
· Alamo
· Thrifty
· Enterprise Rent-A-Car
· Avis
How much should I expect to pay for a La Crosse to Greenville flight?
Round-trip flights from La Crosse to Greenville range from $360 to $437, with an average of $367 over the past 12 months. Anything below $360 counts as a good deal.

If your dates can be flexible, aim for a Thursday departure instead of Tuesday. On this route, Thursday flights average $360 - about $77 less than Tuesday (18% savings) based on the last 12 months.

Everything you need to know for your flight from La Crosse to Greenville

Airports

Cabin class

Complete your trip

Direct Flights

Flights to other cities

Origins

Other airports

Information on your arrival and departure airports

La Crosse (LSE)

Greenville (GSP)

LSE - GSP

$493 Find Cheap Flights from La Crosse to Greenville - Compare and Save

Everything you should know

Cheap Flights from La Crosse to Greenville (LSE-GSP)

Recent round-trip flight deals from La Crosse to Greenville

Recent one-way flight deals from La Crosse to Greenville

Price, demand and travel trends for La Crosse to Greenville flights

How much is a round-trip flight from La Crosse to Greenville?

What is the cheapest airline to fly from La Crosse to Greenville?

What is the cheapest layover airport when flying from La Crosse to Greenville?

When flying from La Crosse to Greenville which airport offers the shortest layover?

Key details for La Crosse to Greenville flights

Cheapest flight

When to book flights from La Crosse to Greenville

Your La Crosse to Greenville flight questions, answered

Your guide to booking La Crosse to Greenville flights

Everything you need to know for your flight from La Crosse to Greenville

Information on your arrival and departure airports

Cabin class types available on flights from La Crosse to Greenville

Complete your trip to Greenville with a hotel stay or car rental

Find direct flights to and from La Crosse and Greenville

Flights to other popular destinations

Flights from domestic origins to Greenville

Choose which airport to fly into in Greenville