LSE - GSP

$372 Find Cheap Flights from La Crosse to Greenville - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$372
Typical prices: $360-$437
American Airlines
Sat 10/27Wed 10/31
LSE - GSP • 1 stop
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Cheap Flights from La Crosse to Greenville (LSE-GSP)

 

Cheap flights from La Crosse to Greenville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Tue, Oct 27 - Sat, Oct 31
American Airlines Logo
12:23 pm - 6:08 pmLSE  La Crosse-GSP Greenville
4h 45m1 stop Chicago O'Hare Intl
American Airlines Logo
6:01 am - 11:53 amGSP  Greenville-LSE La Crosse
6h 52m1 stop Chicago O'Hare Intl
$372American Airlines
Sat, Nov 14 - Mon, Nov 16
American Airlines Logo
5:57 am - 11:07 amLSE  La Crosse-GSP Greenville
4h 10m1 stop Chicago O'Hare Intl
American Airlines Logo
6:42 pm - 12:18 amGSP  Greenville-LSE La Crosse
6h 36m1 stop Chicago O'Hare Intl
$375American Airlines
Tue, Oct 27 - Sat, Oct 31
American Airlines Logo
12:23 pm - 6:08 pmLSE  La Crosse-GSP Greenville
4h 45m1 stop Chicago O'Hare Intl
American Airlines Logo
3:58 pm - 11:59 pmGSP  Greenville-LSE La Crosse
9h 01m2 stops Charlotte Douglas Chicago O'Hare Intl
$378American Airlines
Sat, Nov 14 - Mon, Nov 16
American Airlines Logo
5:57 am - 4:43 pmLSE  La Crosse-GSP Greenville
9h 46m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
American Airlines Logo
6:42 pm - 12:18 amGSP  Greenville-LSE La Crosse
6h 36m1 stop Chicago O'Hare Intl
$381American Airlines
Tue, Oct 27 - Sat, Oct 31
American Airlines Logo
12:23 pm - 10:56 pmLSE  La Crosse-GSP Greenville
9h 33m2 stops Chicago O'Hare Intl Charlotte Douglas
American Airlines Logo
10:03 am - 6:20 pmGSP  Greenville-LSE La Crosse
9h 17m2 stops Charlotte Douglas Chicago O'Hare Intl
$383American Airlines
Sat, Nov 14 - Mon, Nov 16
American Airlines Logo
12:24 pm - 10:54 pmLSE  La Crosse-GSP Greenville
9h 30m2 stops Chicago O'Hare Intl Charlotte Douglas
American Airlines Logo
3:35 pm - 12:18 amGSP  Greenville-LSE La Crosse
9h 43m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl
$386American Airlines
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
12:09 pm - 6:15 pmLSE  La Crosse-GSP Greenville
5h 06m1 stop Chicago O'Hare Intl
American Airlines Logo
11:36 am - 6:21 pmGSP  Greenville-LSE La Crosse
7h 45m1 stop Chicago O'Hare Intl
$450American Airlines
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
12:09 pm - 6:15 pmLSE  La Crosse-GSP Greenville
5h 06m1 stop Chicago O'Hare Intl
American Airlines Logo
7:09 am - 6:21 pmGSP  Greenville-LSE La Crosse
12h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl
$456American Airlines
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
12:09 pm - 8:50 pmLSE  La Crosse-GSP Greenville
7h 41m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
American Airlines Logo
7:09 am - 6:21 pmGSP  Greenville-LSE La Crosse
12h 12m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl
$461American Airlines

Price, demand and travel trends for La Crosse to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from La Crosse to Greenville?

Round-trip flights from La Crosse to Greenville typically range from $360 to $437. The lowest price found in the past 5 days was $372, on American Airlines.

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Key details for La Crosse to Greenville flights

Cheapest flight

$372
Round-trip flight from La Crosse to Greenville

When to book flights from La Crosse to Greenville

Are your dates flexible? Find out the best times to travel from La Crosse to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your La Crosse to Greenville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Do I need a passport to fly from La Crosse to Greenville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from La Crosse to Greenville changed much recently?

    Based on fares seen in the past 5 days, round-trip prices on this route were fairly steady, ranging from about $372 to $383. The highest observed fare was only about 2% higher than the lowest one.

  • What car rental options are available at Greenville Airport (GSP)?

    Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include:

    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Avis

  • Which airports can I use when flying from La Crosse to Greenville?

    Flights from La Crosse to Greenville usually depart from La Crosse (LSE) and arrive at Greenville (GSP).

  • Which airports do connecting flights from La Crosse to Greenville pass through?

    Most connecting flights from La Crosse to Greenville pass through Chicago O'Hare Intl (ORD), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from La Crosse to Greenville?

    Yes. Flexible dates can save you up to 18% on flights from La Crosse to Greenville. Thursday is the cheapest departure day at $360 round-trip on average, while Tuesday is the most expensive at $437, a difference of $77.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between La Crosse and Greenville?

    Greenville is 1 hour ahead of La Crosse (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking La Crosse to Greenville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Tuesday. On this route, Thursday flights average $360, about $77 less than Tuesday fares (18% savings) based on the last 12 months.

More options for your flight from La Crosse to Greenville

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