STL - GSP

$114 Find Cheap Flights from St. Louis to Greenville - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$268
Typical prices: $333-$586
Southwest
Fri 10/12Sun 10/14
STL - GSP • 1 stop
Cheapest one-way
$114
Typical prices: $148-$329
Multiple Airlines
Fri 11/9
STL - GSP • 2 stops
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Greenville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 29% price drop
October
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $308 (round-trip)
Nashville Intl (BNA)
Shortest trip • 3h 54m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Greenville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Greenville (STL-GSP)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Greenville

Mon, Oct 12 - Wed, Oct 14
Southwest Logo
5:50 pm - 10:50 pmSTL  Lambert-St Louis-GSP Greenville
4h 00m1 stop Nashville Intl
Southwest Logo
1:25 pm - 7:20 pmGSP  Greenville-STL Lambert-St Louis
6h 55m1 stop Baltimore/Washington
$268Southwest
Mon, Oct 12 - Wed, Oct 14
Southwest Logo
5:50 pm - 10:50 pmSTL  Lambert-St Louis-GSP Greenville
4h 00m1 stop Nashville Intl
Southwest Logo
8:30 am - 2:55 pmGSP  Greenville-STL Lambert-St Louis
7h 25m2 stops Baltimore/Washington Nashville Intl
$300Southwest
Fri, Oct 9 - Fri, Oct 16
Multiple Airlines Logo
6:35 pm - 9:32 amSTL  Lambert-St Louis-GSP Greenville
37h 57m2 stops Atlanta Hartsfield-Jackson Tampa
Multiple Airlines Logo
8:32 pm - 11:13 pmGSP  Greenville-STL Lambert-St Louis
27h 41m1 stop Orlando
$308Multiple Airlines
Thu, Nov 19 - Mon, Nov 30
Multiple Airlines Logo
4:26 pm - 3:47 pmSTL  Lambert-St Louis-GSP Greenville
22h 21m1 stop Orlando
Multiple Airlines Logo
8:32 pm - 12:41 amGSP  Greenville-STL Lambert-St Louis
29h 09m1 stop Orlando
$327Multiple Airlines
Sat, Oct 17 - Sun, Oct 18
American Airlines Logo
3:20 pm - 10:05 pmSTL  Lambert-St Louis-GSP Greenville
5h 45m1 stop Dallas/Fort Worth
American Airlines Logo
8:33 pm - 11:59 pmGSP  Greenville-STL Lambert-St Louis
4h 26m1 stop Charlotte Douglas
$328American Airlines
Fri, Oct 9 - Fri, Oct 16
Southwest Logo
2:30 pm - 8:00 pmSTL  Lambert-St Louis-GSP Greenville
4h 30m1 stop Nashville Intl
Southwest Logo
8:40 pm - 11:40 pmGSP  Greenville-STL Lambert-St Louis
4h 00m1 stop Nashville Intl
$346Southwest
Thu, Nov 19 - Mon, Nov 30
Multiple Airlines Logo
4:26 pm - 7:52 pmSTL  Lambert-St Louis-GSP Greenville
26h 26m2 stops Orlando Columbus
Multiple Airlines Logo
8:32 pm - 12:41 amGSP  Greenville-STL Lambert-St Louis
29h 09m1 stop Orlando
$352Multiple Airlines
Tue, Dec 1 - Sat, Dec 5
American Airlines Logo
5:00 am - 12:07 pmSTL  Lambert-St Louis-GSP Greenville
6h 07m1 stop Charlotte Douglas
American Airlines Logo
7:46 am - 12:28 pmGSP  Greenville-STL Lambert-St Louis
5h 42m1 stop Dallas/Fort Worth
$385American Airlines
Fri, Oct 23 - Sun, Oct 25
Delta Logo
5:35 pm - 10:51 pmSTL  Lambert-St Louis-GSP Greenville
4h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 9:09 amGSP  Greenville-STL Lambert-St Louis
4h 29m1 stop Atlanta Hartsfield-Jackson
$386Delta
Thu, Nov 5 - Sat, Nov 7
Delta Logo
7:00 am - 8:21 pmSTL  Lambert-St Louis-GSP Greenville
12h 21m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:05 am - 10:51 amGSP  Greenville-STL Lambert-St Louis
3h 46m1 stop Atlanta Hartsfield-Jackson
$450Delta
Booking Insights

Price, demand and travel trends for St. Louis to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from St. Louis to Greenville with more confidence.

How much is a round-trip flight from St. Louis to Greenville?

Round-trip flights from St. Louis to Greenville start at $268. Prices are below average for this route right now, with typical round-trip fares ranging from $333 to $586. The lowest price found in the past 5 days was $268 on Southwest.

What's the cheapest day of the week to fly from St. Louis to Greenville?

Wednesday is the cheapest day of the week to fly from St. Louis to Greenville, it is 21% cheaper than the average day. Friday is the most expensive day with flight prices 30% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from St. Louis to Greenville?

  • October is the cheapest month to fly from St. Louis to Greenville at $297 round-trip.
  • January ($841) and February ($840) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 183% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for St. Louis to Greenville flights

Low season

January

Cheapest flight

$114
Best time to beat the crowds but there is an average 101% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from St. Louis to Greenville

When to book flights from St. Louis to Greenville

Are your dates flexible? Find out the best times to travel from St. Louis to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Greenville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from St. Louis to Greenville?

    Flights from St. Louis to Greenville usually depart from Lambert-St Louis (STL) and arrive at Greenville (GSP).

  • What cabin classes can I book on flights from St. Louis to Greenville?

    Two cabin classes are available on flights from St. Louis to Greenville:

    • Economy Class
    • First Class

  • Which airports do connecting flights from St. Louis to Greenville pass through?

    One-stop flights from St. Louis to Greenville most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 40% of one-stop connections
    • Nashville Intl (BNA) - 38% of one-stop connections
    • Charlotte Douglas (CLT) - 19% of one-stop connections
    • Dallas/Fort Worth (DFW) - 2% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from St. Louis to Greenville?

    Yes. Being flexible with your travel dates can save you up to 40% on the St. Louis to Greenville route. Wednesday is the cheapest departure day at $333 round-trip on average, while Friday is the most expensive at $547, a difference of $214. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from St. Louis to Greenville?

    A nonstop flight from St. Louis to Greenville takes 0h 00m, covering 523 miles.

  • Do I need a passport to fly from St. Louis to Greenville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from St. Louis to Greenville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $268 to $1,163. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from St. Louis to Greenville looking right now?

    One-way fares from St. Louis to Greenville are currently lower than usual. Average one-way flight prices are about $154, which is 31% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from St. Louis to Greenville?

    Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 54m, compared with 4h 07m via Atlanta Hartsfield-Jackson (ATL) and 4h 34m via Chicago O'Hare Intl (ORD).

  • What is the time difference between St. Louis and Greenville?

    Greenville is 1 hour ahead of St. Louis (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Greenville Airport (GSP)?

    Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Avis

  • How much should I expect to pay for a St. Louis to Greenville flight?

    Round-trip flights from St. Louis to Greenville range from $333 to $586, with an average of $418 over the past 12 months. Anything below $333 counts as a good deal.

Your guide to booking St. Louis to Greenville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average $333 - about $214 less than Friday (39% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Greenville trip for October. Fares historically average $297 round-trip in that month - typically $544 less than the most expensive month, which is January (based on the last 12 months).

More options for your flight from St. Louis to Greenville

Complete your trip to Greenville with a hotel stay or car rental

Car rentals in Greenville
Hotels in Greenville
Vacations in Greenville