STL - SDQ

$160 Find Cheap Flights from St. Louis to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santo Domingo departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santo Domingo, as well as popular online travel agencies
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Flight Deals

Cheap Flights from St. Louis to Santo Domingo (STL-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santo Domingo

Tue, Oct 14 - Tue, Oct 21
Delta Logo
6:00 am - 1:41 pmSTL-SDQ
6h 41m1 stop
Delta Logo
2:56 pm - 10:04 pmSDQ-STL
8h 08m1 stop
$515Delta
Find Deal
Tue, Oct 14 - Tue, Oct 21
Delta Logo
6:40 am - 6:24 pmSTL-SDQ
10h 44m2 stops
Delta Logo
6:05 am - 5:29 pmSDQ-STL
12h 24m2 stops
$519Delta
Find Deal
Fri, Nov 7 - Sat, Nov 15
American Airlines Logo
5:56 pm - 12:19 pmSTL-SDQ
16h 23m2 stops
American Airlines Logo
6:00 am - 4:34 pmSDQ-STL
12h 34m2 stops
$542American Airlines
Find Deal
Mon, Jan 5 - Tue, Jan 13
American Airlines Logo
6:00 pm - 11:35 amSTL-SDQ
15h 35m1 stop
American Airlines Logo
8:50 am - 9:48 pmSDQ-STL
14h 58m1 stop
$569American Airlines
Find Deal
Tue, Oct 28 - Tue, Nov 4
United Airlines Logo
11:49 am - 10:46 pmSTL-SDQ
9h 57m1 stop
United Airlines Logo
4:18 pm - 11:44 pmSDQ-STL
9h 26m1 stop
$626United Airlines
Find Deal
Sun, Dec 21 - Wed, Dec 24
 Logo
3:40 pm - 10:11 amSTL-SDQ
16h 31m1 stop
 Logo
4:44 am - 11:01 amSDQ-STL
8h 17m1 stop
Thu, Jan 1 - Tue, Jan 6
Frontier Logo
5:33 pm - 10:11 amSTL-SDQ
14h 38m2 stops
Frontier Logo
10:56 am - 10:33 pmSDQ-STL
13h 37m1 stop
$780Frontier
Find Deal
Sun, Dec 21 - Wed, Dec 24
 Logo
5:33 pm - 4:29 pmSTL-SDQ
20h 56m2 stops
 Logo
4:44 am - 11:01 amSDQ-STL
8h 17m1 stop
Tue, Oct 28 - Tue, Nov 4
United Airlines Logo
11:49 am - 10:46 pmSTL-SDQ
9h 57m1 stop
United Airlines Logo
6:00 am - 10:45 pmSDQ-STL
18h 45m2 stops
$889United Airlines
Find Deal
Sun, Dec 21 - Mon, Jan 5
Frontier Logo
3:40 pm - 10:11 amSTL-SDQ
16h 31m1 stop
Frontier Logo
11:26 am - 10:46 pmSDQ-STL
13h 20m1 stop
$905Frontier
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $515 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
February
Cheapest • 21% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$515
Overall average: $1,094
Delta
Tue 10/14Tue 10/21
STL - SDQ • 1 stop
Cheapest one-way
$160
Spirit Airlines
Thu 10/23
STL - SDQ • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Booking Insights

KAYAK's insights & trends for St. Louis to Santo Domingo flights

Get data-powered insights and trends into flights from St. Louis to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to Santo Domingo?

The average price of all round-trip flights from St. Louis to Santo Domingo clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santo Domingo on a Wednesday and more expensive on a Friday. On your return trip to St. Louis, you should consider flying back on a Wednesday, and avoid Saturdays for better deals.

What is the cheapest month to fly from St. Louis to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Santo Domingo is February, where tickets cost $531 (return) on average. On the other hand, the most expensive months are October and July, where the average cost of round-trip tickets is $1,094 and $806 respectively.

Good to know

Low seasonAugust
Cheapest flight$160
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from St. Louis to Santo Domingo

When to book flights from St. Louis to Santo Domingo

Are your dates flexible? Find out the best times to travel from St. Louis to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santo Domingo

  • What is the cheapest flight from St. Louis to Santo Domingo?

    In the last 3 days, the lowest price for a flight from St. Louis to Santo Domingo was $160 for a one-way ticket and $515 for a round-trip.

  • Do I need a passport to fly between St. Louis and Santo Domingo?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santo Domingo.

  • Which aircraft models fly most regularly from St. Louis to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santo Domingo?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between St. Louis and Santo Domingo, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Santo Domingo are Delta and American Airlines. With an average price for the route of $603 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $644 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from St. Louis to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from St. Louis to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
7.9Comfort
7.3Food
8.2Boarding
8.5Crew
7.9Entertainment
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Given it’s a red-eye into Charolotte, we didn’t get any food. The survey does not include “N/A” so the rating will be skewed.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

American airlines suck they delay the flights all the time made me sleep in an airport because my flight was delayed and I miss my connecting flight

There's nothing I liked about it. For first off I scheduled this trip two weeks in advance then they delayed my flight which messed up my whole trip. So I scheduled it for the following weekend thinking there won't be a delay and guess what as soon as I got to the airport we said in the airplane on the tarmac for an hour and a half. Not only was it delayed I missed my connecting flight meaning I had to stay the night at Dallas-Fort Worth airport sleeping on the floor. I will tell you this I will never fly American airlines ever again I have had nothing but horrible experience with them and I just throw money at them

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Don’t know they cancelled the flight day before I was to leave. They sent a email at 9:00 pm at night saying they cancelled. That is the smooth way to say we don’t want your business! I think they didn’t have enough people booking so they cancelled the flight! It’s all about the money anymore there is no honesty in business.

Having to reschedule flights a day later, they loaded by luggage on the wrong plane from Little rock now I have to HOPE they deliver it to where im staying like they said would. International flight crew was very disgruntled and not very friendly.

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

It took way too long to diagnose and solve the problem of a broken crew member cabin seat. Though compensation for the volunteer who left the flight was very kind.

The entertainment package was vast and the selections were very current. Keep updating it was great.

Seats were new and comfortable. Staff was fine. Missed my connection due to weather -which wasn’t their fault- but got no help at all. Gate staff sent me to customer service, which was and stayed unstaffed. Sign with QR code directed me to call or chat. Chat was useless. Call was returned after an hour. No itinerary offered by Frontier could get me home in less than 30 hours. Rebooked with another airline and got a partial refund that came to about 10 percent of what I paid to get home.

Finally a Frontier on time and efficient. I've had problems before with your airline, but this time everything went fine.

The experience was good. No frills but I got there safe and sound and on time.

Great for the price. No wifi or entertainment, but gate agents and crew were fantastic and we boarded quickly and left on time.

sluggish boarding and arrival procedures, fake nice flight attendants, and lots of delays.

Disaster. They lied every step of the way. We ended up being delayed due to crew and then allegedly abandoned the flight because of a curfew at LGA. No rebooking to LGA at any reasonable time. No hotel. No meal vouchers. Had to sleep in the airport and fly to Newark instead. Will never fly Frontier again.

What I expected, nickeled and dined and a frontier flight attendant loudly complained about her job and lack of communication as she headed to the gate on her cell phone. Not professional.

As every law enforcement agency I could imagine surrounded the plane and we didn’t disembark for 2 hours and then had to stick around for another hour to go get our personal belongings after leaving them behind and being bused away from the plane, it was scary and inconvenient. We were given no information as to why this was happening. Lack of communication with passengers was disappointing.

After boarding and un-boarding twice over 6+hours, the flight was canceled.

Severe turbulence. Captain never came on to reassure passengers after things settled down.

Everything you need to know for your flight from St. Louis to Santo Domingo

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