STL - SDQ

$279 Find Cheap Flights from St. Louis to Santo Domingo - Compare and Save

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Everything you should know

Cheapest round-trip
$470
Typical prices: $620-$826
Frontier
Sun 12/2Thu 12/6
STL - SDQ • 1 stop
Cheapest one-way
$279
Typical prices: $367-$483
Frontier
Sat 12/29
STL - SDQ • 1 stop
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
March
Cheapest • 16% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Miami (MIA)
Cheapest • Avg $732 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 8h 52m (one-way)
Insights
Insights
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We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santo Domingo (STL-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santo Domingo

Wed, Dec 2 - Sun, Dec 6
Frontier Logo
6:13 pm - 1:18 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
17h 05m1 stop Orlando
Frontier Logo
2:25 pm - 12:12 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
11h 47m1 stop Orlando
$470Frontier
Wed, Dec 2 - Sun, Dec 6
Frontier Logo
12:05 pm - 1:18 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
23h 13m2 stops Atlanta Hartsfield-Jackson Orlando
Frontier Logo
2:25 pm - 12:12 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
11h 47m1 stop Orlando
$489Frontier
Wed, Dec 2 - Sun, Dec 6
Frontier Logo
7:58 pm - 1:18 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
15h 20m2 stops Denver Intl Orlando
Frontier Logo
2:25 pm - 11:17 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
22h 52m2 stops Orlando Atlanta Hartsfield-Jackson
$549Frontier
Wed, Dec 2 - Sun, Dec 6
Multiple Airlines Logo
6:13 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
26h 59m3 stops Orlando Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
1:27 pm - 10:57 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
23h 30m3 stops Philadelphia Atlanta Hartsfield-Jackson Denver Intl
$557Multiple Airlines
Wed, Dec 2 - Sun, Dec 6
Multiple Airlines Logo
12:05 pm - 1:18 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
23h 13m3 stops Atlanta Hartsfield-Jackson Philadelphia Orlando
Multiple Airlines Logo
3:09 pm - 11:17 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
22h 08m2 stops Miami Atlanta Hartsfield-Jackson
$570Multiple Airlines
Mon, Nov 30 - Thu, Dec 3
Frontier Logo
6:05 pm - 12:04 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
15h 59m2 stops Orlando Philadelphia
Frontier Logo
2:33 pm - 12:12 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
11h 39m1 stop Orlando
$595Frontier
Mon, Nov 30 - Thu, Dec 3
Multiple Airlines Logo
3:04 pm - 9:45 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
28h 41m3 stops Denver Intl Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
5:02 pm - 11:17 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
20h 15m2 stops Miami Atlanta Hartsfield-Jackson
$622Multiple Airlines
Mon, Nov 30 - Thu, Dec 3
Multiple Airlines Logo
6:05 pm - 12:04 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
15h 59m2 stops Orlando Philadelphia
Multiple Airlines Logo
5:02 pm - 11:17 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
20h 15m2 stops Miami Atlanta Hartsfield-Jackson
$631Multiple Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
6:15 pm - 10:05 amSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
13h 50m1 stop Miami
American Airlines Logo
2:22 pm - 8:46 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
8h 24m1 stop Philadelphia
$680American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
6:47 am - 9:42 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
12h 55m2 stops Charlotte Douglas Miami
American Airlines Logo
2:22 pm - 8:46 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
8h 24m1 stop Philadelphia
$685American Airlines
Booking Insights

Price, demand and travel trends for St. Louis to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from St. Louis to Santo Domingo?

Round-trip flights from St. Louis to Santo Domingo typically range from $620 to $826. The lowest price found in the past 5 days was $470, on Frontier.

What's the cheapest day of the week to fly from St. Louis to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from St. Louis to Santo Domingo. It’s 12% cheaper than the average day, while Wednesday is the most expensive, with prices 13% higher.

What’s the cheapest month to fly from St. Louis to Santo Domingo?

•March is the cheapest month to fly from St. Louis to Santo Domingo at $613 round-trip.
•December ($880) and May ($833) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 43% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for St. Louis to Santo Domingo flights

Low season

May

Cheapest flight

$279
Beat the crowds with an average 46% drop in travelers.
The most popular month to fly with an average 76% increase in travelers.
One-way flight from St. Louis to Santo Domingo

When to book flights from St. Louis to Santo Domingo

Are your dates flexible? Find out the best times to travel from St. Louis to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from St. Louis to Santo Domingo?

    Only Economy Class is available on flights from St. Louis to Santo Domingo.

  • How long is a flight from St. Louis to Santo Domingo?

    A nonstop flight from St. Louis to Santo Domingo takes 00m, covering 1,873 miles.

  • Do I need a passport to fly from St. Louis to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a St. Louis to Santo Domingo flight?

    Round-trip flights from St. Louis to Santo Domingo range from $620 to $826, with an average of $729 over the past 12 months. Anything below $620 counts as a good deal.

  • Have flight prices from St. Louis to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $470 to $1,254. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from St. Louis to Santo Domingo looking right now?

    One-way fares from St. Louis to Santo Domingo are currently in line with typical prices for this route. Average one-way fares are about $422.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates averaging $31 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from St. Louis to Santo Domingo?

    Flights from St. Louis to Santo Domingo usually depart from Lambert-St Louis (STL) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from St. Louis to Santo Domingo pass through?

    Connecting flights from St. Louis to Santo Domingo most commonly pass through:

    • Miami (MIA) - 81% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 19% of one-stop connections

  • Can I save money by using flexible dates for flights from St. Louis to Santo Domingo?

    Yes. Flexible dates can save you up to 23% on flights from St. Louis to Santo Domingo. Tuesday is the cheapest departure day at $644 round-trip on average, while Wednesday is the most expensive at $826, a difference of $182.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from St. Louis to Santo Domingo?

    Flying via Miami (MIA) gives the shortest average 1-stop total travel time at 8h 37m, compared with 8h 52m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between St. Louis and Santo Domingo?

    Santo Domingo is 2 hours ahead of St. Louis (Atlantic Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking St. Louis to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Wednesday. On this route, Tuesday flights average $644, about $182 less than Wednesday fares (22% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Santo Domingo trip for March. Fares historically average $613 round-trip in that month - typically $267 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from St. Louis to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo