STL - SDQ

$305 Find Cheap Flights from St. Louis to Santo Domingo - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$458
Typical prices: $600-$826
Multiple Airlines
Sun 10/14Sun 10/21
STL - SDQ • 2 stops
Cheapest one-way
$253
Typical prices: $362-$469
Frontier
Sun 12/30
STL - SDQ • 1 stop
Nonstop flights
There are currently no direct flights between St. Louis and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
Cheapest • 18% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $706 (round-trip)
Shortest trip • 8h 25m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santo Domingo (STL-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santo Domingo

Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
10:19 am - 11:31 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
26h 12m3 stops Miami Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl
$458Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
10:19 am - 11:31 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
26h 12m3 stops Miami Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl
$465Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m3 stops Atlanta Hartsfield-Jackson Baltimore/Washington Miami
Multiple Airlines Logo
10:19 am - 11:31 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
26h 12m3 stops Miami Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl
$512Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m3 stops Atlanta Hartsfield-Jackson Baltimore/Washington Miami
Multiple Airlines Logo
10:19 am - 11:31 amSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
26h 12m3 stops Miami Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl
$520Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
7:10 pm - 11:13 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
29h 03m2 stops Newark Orlando
$524Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
7:10 pm - 11:13 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
29h 03m2 stops Newark Orlando
$531Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
7:10 pm - 11:13 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
29h 03m2 stops Newark Orlando
$534Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
Multiple Airlines Logo
6:35 pm - 11:12 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
27h 37m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
7:10 pm - 11:13 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
29h 03m2 stops Newark Orlando
$537Multiple Airlines
Wed, Oct 14 - Wed, Oct 21
American Airlines Logo
5:08 pm - 9:22 amSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
15h 14m2 stops Washington, D.C. Reagan-National Miami
American Airlines Logo
1:35 pm - 10:14 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
9h 39m1 stop Philadelphia
$616American Airlines
Tue, Oct 13 - Tue, Oct 20
American Airlines Logo
5:00 am - 1:33 pmSTL  Lambert-St Louis-SDQ Santo Domingo Las Americas
7h 33m1 stop Miami
American Airlines Logo
2:33 pm - 9:59 pmSDQ  Santo Domingo Las Americas-STL Lambert-St Louis
8h 26m1 stop Miami
$620American Airlines
Booking Insights

Price, demand and travel trends for St. Louis to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from St. Louis to Santo Domingo with more confidence.

What's the cheapest day of the week to fly from St. Louis to Santo Domingo?

Tuesday is the cheapest day of the week to fly from St. Louis to Santo Domingo, it is 10% cheaper than the average day. Wednesday is the most expensive day with flight prices 18% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from St. Louis to Santo Domingo?

•September is the cheapest month to fly from St. Louis to Santo Domingo at $574 round-trip.
•May ($833) and November ($826) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 45% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Key details for St. Louis to Santo Domingo flights

Low season

May

Cheapest flight

$253
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly with an average 19% increase in price.
Flight from St. Louis to Santo Domingo

When to book flights from St. Louis to Santo Domingo

Are your dates flexible? Find out the best times to travel from St. Louis to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Santo Domingo flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from St. Louis to Santo Domingo?

    Flights from St. Louis to Santo Domingo usually depart from Lambert-St Louis (STL) and arrive at Santo Domingo Las Americas (SDQ).

  • What cabin classes can I book on flights from St. Louis to Santo Domingo?

    Only Economy Class is available on flights from St. Louis to Santo Domingo.

  • Which airports do connecting flights from St. Louis to Santo Domingo pass through?

    Connecting flights from St. Louis to Santo Domingo most commonly pass through:

    • Miami (MIA) - 78% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 22% of one-stop connections
    Together, these airports account for 100% of one-stop bookings on this route.

  • Can I save money by using flexible dates for flights from St. Louis to Santo Domingo?

    Yes. Being flexible with your travel dates can save you up to 24% on the St. Louis to Santo Domingo route. Tuesday is the cheapest departure day at $629 round-trip on average, while Wednesday is the most expensive at $826, a difference of $197. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

  • How long is a flight from St. Louis to Santo Domingo?

    A nonstop flight from St. Louis to Santo Domingo takes 0h 00m, covering 1,873 miles.

  • Do I need a passport to fly from St. Louis to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from St. Louis to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $458 to $3,372. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from St. Louis to Santo Domingo looking right now?

    One-way fares from St. Louis to Santo Domingo are currently lower than usual. Average one-way flight prices are about $332, which is 21% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from St. Louis to Santo Domingo?

    Flying via Miami (MIA) gives the shortest average 1-stop total travel time at 8h 24m, compared with 8h 25m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between St. Louis and Santo Domingo?

    Santo Domingo is 1 hour ahead of St. Louis (Atlantic Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around $7 for economy cars. Top options include:
    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • How much should I expect to pay for a St. Louis to Santo Domingo flight?

    Round-trip flights from St. Louis to Santo Domingo range from $600 to $826, with an average of $696 over the past 12 months. Anything below $600 counts as a good deal.

Your guide to booking St. Louis to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Tuesday departure instead of Wednesday. On this route, Tuesday flights average $629 - about $197 less than Wednesday (24% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Santo Domingo trip for September. Fares historically average $574 round-trip in that month - typically $259 less than the most expensive month, which is May (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.
    - Hampton by Hilton Santo Domingo Airport

More options for your flight from St. Louis to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental