STL - SDQ

$213 Find Cheap Flights from St. Louis to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santo Domingo departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$408
Overall average: $644
Frontier
Thu 4/2Wed 4/8
STL - SDQ • 1 stop
Cheapest one-way
$213
Multiple Airlines
Wed 5/13
STL - SDQ • 2 stops
Top airlines
Cheapest • from $597 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $684 (round-trip)
Shortest trip • 6h 18m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 18% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santo Domingo (STL-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santo Domingo

Thu, Apr 2 - Wed, Apr 8
Frontier Logo
4:54 pm - 10:07 am
STL
-
SDQ
16h 13m
1 stop
Frontier Logo
4:35 pm - 11:25 pm
SDQ
-
STL
7h 50m
1 stop
$408Frontier
Thu, Apr 2 - Wed, Apr 8
Frontier Logo
4:54 pm - 10:07 am
STL
-
SDQ
16h 13m
1 stop
Frontier Logo
4:35 pm - 5:34 pm
SDQ
-
STL
25h 59m
2 stops
$440Frontier
Thu, Apr 2 - Wed, Apr 8
Frontier Logo
6:29 pm - 10:07 am
STL
-
SDQ
14h 38m
2 stops
Frontier Logo
4:08 pm - 7:51 am
SDQ
-
STL
40h 43m
2 stops
$585Frontier
Tue, Apr 28 - Tue, May 5
American Airlines Logo
5:51 am - 4:55 pm
STL
-
SDQ
10h 04m
2 stops
American Airlines Logo
6:00 am - 4:41 pm
SDQ
-
STL
11h 41m
2 stops
$597American Airlines
Fri, May 1 - Fri, May 8
American Airlines Logo
6:29 am - 4:55 pm
STL
-
SDQ
9h 26m
2 stops
American Airlines Logo
4:00 pm - 10:24 pm
SDQ
-
STL
7h 24m
1 stop
$604American Airlines
Thu, Apr 30 - Thu, May 7
American Airlines Logo
5:24 am - 4:55 pm
STL
-
SDQ
10h 31m
1 stop
American Airlines Logo
2:25 pm - 10:24 pm
SDQ
-
STL
8h 59m
1 stop
$609American Airlines
Thu, Apr 30 - Thu, May 7
United Airlines Logo
7:45 am - 10:46 pm
STL
-
SDQ
14h 01m
2 stops
United Airlines Logo
3:20 pm - 11:57 pm
SDQ
-
STL
9h 37m
1 stop
$613United Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
5:21 am - 4:55 pm
STL
-
SDQ
10h 34m
1 stop
American Airlines Logo
5:55 pm - 10:16 am
SDQ
-
STL
17h 21m
1 stop
$619American Airlines
Mon, Apr 13 - Mon, Apr 20
Delta Logo
9:59 am - 12:17 am
STL
-
SDQ
13h 18m
2 stops
Delta Logo
7:59 pm - 10:34 am
SDQ
-
STL
15h 35m
2 stops
$623Delta
Sat, Apr 18 - Mon, Apr 20
Delta Logo
6:00 am - 1:12 pm
STL
-
SDQ
6h 12m
1 stop
Delta Logo
7:59 pm - 10:34 am
SDQ
-
STL
15h 35m
2 stops
$633Delta
Booking Insights

KAYAK's insights & trends for St. Louis to Santo Domingo flights

Get data-powered insights and trends into flights from St. Louis to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from St. Louis to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Santo Domingo is September, where tickets cost $533 (return) on average. On the other hand, the most expensive months are November and July, where the average cost of round-trip tickets is $826 and $808 respectively.

Good to know

Low seasonFebruary
Cheapest flight$213
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from St. Louis to Santo Domingo

When to book flights from St. Louis to Santo Domingo

Are your dates flexible? Find out the best times to travel from St. Louis to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Santo Domingo

  • What is the cheapest flight from St. Louis to Santo Domingo?

    In the last 3 days, the lowest price for a flight from St. Louis to Santo Domingo was $213 for a one-way ticket and $597 for a round-trip.

  • Do I need a passport to fly between St. Louis and Santo Domingo?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Santo Domingo.

  • Which aircraft models fly most regularly from St. Louis to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between St. Louis and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Santo Domingo are Delta and American Airlines. With an average price for the route of $594 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $644 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from St. Louis to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from St. Louis to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8286 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.2Food
7.8Entertainment
Airline reviews

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

2.0 MediocreANTHONY, Mar 2026
SLC - HNL
Read more Delta reviews

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

Horrible experience upon landing. Probably more due to DCA utter incompetence than AA.

Jill was the flight attendant in first class she was fabulous!! Best flight attendant I have had in years.!! And I fly every other week. Other can learn from her!!

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

My 9:50AM flight was delayed to 3:40PM "due to incoming aircraft delay". No aircraft is "delayed" that long. Found out once we did board (after several changes in times) that the aircraft had a maintenance issue and we had to wait for another aircraft. Just tell us that. The aircraft we did get was old and the seats need to be updated. I have been traveling for several weeks with AA and you should refresh your entertainment content as frequent flyers have gone through most of your new content. I have Celiac and a shellfish allergy and continue to have struggles with meals on business and first class flights. Please keep this in mind. Sorry - was a long travel day yesterday and a bit cranky this morning with my experience comments. Still an AA fan.

The business steward was absolutely amazing! Smiles and kindness! Wish all AA flights are like this one!

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Not really sure I enjoyed the flight at all. The flight attendants seemed a little tired and rude at times. The snacks were lacking in taste and sustenance. The flight was incredibly turbulent for three plus hours and the pilot had to do a second pass to land at our final destination because he was coming in so fast. He must have taken a short cut and because of it we had to suffer the violent turbulence and the dropping down. It had to be one of if not the worse flights I have ever been on and have traveled vastly all over the world.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

Everything you need to know for your flight from St. Louis to Santo Domingo

Information on your arrival and departure airports