$198 Find Cheap Flights from Lexington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Lexington to South America departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Lexington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$787
Bogotá
Bogotá1 stop$473
Rio de Janeiro
Rio de Janeiro2 stops$1,241
Santiago
Santiago2 stops$922
Cartagena
Cartagena2 stops$670
Quito
Quito2 stops$683
Guayaquil
Guayaquil2 stops$715
Barranquilla
Barranquilla2 stops$1,086
Lima
Lima2 stops$787
Bogotá
Bogotá1 stop$473
Rio de Janeiro
Rio de Janeiro2 stops$1,241
Santiago
Santiago2 stops$922
Cartagena
Cartagena2 stops$670
Quito
Quito2 stops$683
Guayaquil
Guayaquil2 stops$715
Barranquilla
Barranquilla2 stops$1,086

Book Cheap Lexington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Lexington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Lexington to South America

Thu, Jun 4 - Mon, Jun 15
Multiple Airlines Logo
3:06 pm - 1:12 pm
LEX
-
BOG
23h 06m
1 stop
Multiple Airlines Logo
2:07 pm - 12:27 pm
BOG
-
LEX
21h 20m
1 stop
$473Multiple Airlines
Thu, Jun 4 - Mon, Jun 15
Multiple Airlines Logo
9:31 pm - 1:12 pm
LEX
-
BOG
16h 41m
2 stops
Multiple Airlines Logo
2:07 pm - 12:27 pm
BOG
-
LEX
21h 20m
1 stop
$477Multiple Airlines
Sun, May 17 - Thu, May 21
United Airlines Logo
7:50 pm - 9:10 pm
LEX
-
MDE
26h 20m
2 stops
United Airlines Logo
9:45 am - 9:16 am
MDE
-
LEX
22h 31m
2 stops
$642United Airlines
Sun, May 17 - Thu, May 21
United Airlines Logo
7:50 pm - 9:10 pm
LEX
-
MDE
26h 20m
2 stops
United Airlines Logo
9:45 am - 10:30 pm
MDE
-
LEX
35h 45m
2 stops
$659United Airlines
Thu, May 14 - Mon, May 18
American Airlines Logo
5:51 pm - 2:04 pm
LEX
-
CTG
21h 13m
2 stops
American Airlines Logo
3:10 pm - 10:31 am
CTG
-
LEX
18h 21m
2 stops
$670American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
11:28 am - 12:09 pm
LEX
-
CTG
25h 41m
2 stops
American Airlines Logo
1:25 pm - 11:48 am
CTG
-
LEX
21h 23m
2 stops
$674American Airlines
Tue, Apr 21 - Tue, Apr 28
Delta Logo
7:19 am - 1:20 pm
LEX
-
CTG
7h 01m
1 stop
Delta Logo
2:35 pm - 11:54 pm
CTG
-
LEX
8h 19m
1 stop
$709Delta
Tue, Apr 21 - Tue, Apr 28
Delta Logo
6:00 am - 1:20 pm
LEX
-
CTG
8h 20m
1 stop
Delta Logo
4:25 am - 7:10 pm
CTG
-
LEX
13h 45m
2 stops
$712Delta
Wed, Jul 8 - Sun, Aug 2
LATAM Airlines Logo
8:13 pm - 8:55 pm
LEX
-
LIM
25h 42m
2 stops
LATAM Airlines Logo
8:55 am - 9:24 am
LIM
-
LEX
23h 29m
2 stops
$863LATAM Airlines
Thu, May 14 - Mon, May 18
LATAM Airlines Logo
5:55 am - 11:35 pm
LEX
-
CTG
18h 40m
2 stops
LATAM Airlines Logo
4:25 am - 10:05 pm
CTG
-
LEX
16h 40m
3 stops
$890LATAM Airlines
Booking Insights

KAYAK's insights & trends for Lexington to South America flights

Get data-powered insights and trends into flights from Lexington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Lexington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Lexington to South America were found on LATAM Airlines ($630) and United Airlines ($642).

Good to know

Low seasonOctober
Cheapest flight$198
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Lexington to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Lexington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Lexington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Lexington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Lexington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Lexington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Lexington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Lexington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Lexington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Lexington to South America

 
Need help choosing which airline to fly with from Lexington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8356 reviews
8.5Crew
7.8Entertainment
7.2Food
8.1Boarding
7.9Comfort
Airline reviews

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

10.0 ExcellentChristopher, Mar 2026
JFK - MXP
Read more Delta reviews

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

It was fine. 55 minute flight. No snacks or beverage service offered. Boarding went smoothly and my walker was waiting for me on the jet way.

Smaller plane for a longer flight than my first one. Doesn’t make sense.

Everything you need to know for your flight to South America

Information on your arrival and departure airports