$275 Find Cheap Flights from Lexington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Lexington to South America departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Lexington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$820
Bogotá
Bogotá1 stop$565
Rio de Janeiro
Rio de Janeiro2 stops$1,346
Santiago
Santiago2 stops$963
Cartagena
Cartagena1 stop$414
Quito
Quito2 stops$683
Guayaquil
Guayaquil2 stops$680
Cusco
Cusco3 stops$1,191
Lima
Lima2 stops$820
Bogotá
Bogotá1 stop$565
Rio de Janeiro
Rio de Janeiro2 stops$1,346
Santiago
Santiago2 stops$963
Cartagena
Cartagena1 stop$414
Quito
Quito2 stops$683
Guayaquil
Guayaquil2 stops$680
Cusco
Cusco3 stops$1,191

Book Cheap Lexington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Lexington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Lexington to South America

Thu, Apr 16 - Wed, Apr 22
Multiple Airlines Logo
9:31 am - 12:06 pm
LEX
-
CTG
27h 35m
1 stop
Multiple Airlines Logo
1:11 pm - 8:41 am
CTG
-
LEX
18h 30m
1 stop
$414Multiple Airlines
Sat, Jun 13 - Wed, Jul 1
Multiple Airlines Logo
5:32 pm - 1:12 pm
LEX
-
BOG
20h 40m
1 stop
Multiple Airlines Logo
2:25 pm - 2:16 pm
BOG
-
LEX
22h 51m
1 stop
$565Multiple Airlines
Wed, Jun 10 - Tue, Jul 7
Delta Logo
7:10 am - 7:15 pm
LEX
-
BOG
13h 05m
1 stop
Delta Logo
9:00 am - 9:21 pm
BOG
-
LEX
11h 21m
1 stop
$630Delta
Sat, Jul 4 - Fri, Jul 17
American Airlines Logo
11:15 am - 11:58 pm
LEX
-
MDE
13h 43m
2 stops
American Airlines Logo
12:30 am - 4:31 pm
MDE
-
LEX
15h 01m
2 stops
$642American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
2:15 pm - 12:09 pm
LEX
-
CTG
22h 54m
2 stops
American Airlines Logo
1:25 pm - 2:57 pm
CTG
-
LEX
24h 32m
2 stops
$673American Airlines
Tue, Apr 21 - Tue, Apr 28
Delta Logo
6:00 am - 1:20 pm
LEX
-
CTG
8h 20m
1 stop
Delta Logo
2:35 pm - 11:54 pm
CTG
-
LEX
8h 19m
1 stop
$709Delta
Sun, Aug 16 - Sun, Aug 23
United Airlines Logo
9:00 am - 9:10 pm
LEX
-
MDE
37h 10m
2 stops
United Airlines Logo
9:45 am - 12:09 am
MDE
-
LEX
37h 24m
2 stops
$716United Airlines
Thu, Jul 2 - Thu, Jul 16
United Airlines Logo
7:44 pm - 9:10 pm
LEX
-
MDE
26h 26m
2 stops
United Airlines Logo
9:45 am - 9:21 am
MDE
-
LEX
22h 36m
2 stops
$731United Airlines
Sat, Apr 18 - Wed, Apr 22
Avianca Logo
6:01 pm - 7:15 pm
LEX
-
CTG
26h 14m
2 stops
Avianca Logo
1:30 pm - 9:20 am
CTG
-
LEX
42h 50m
2 stops
$796Avianca
Sat, Apr 18 - Wed, Apr 22
Avianca Logo
6:01 pm - 11:30 am
LEX
-
CTG
18h 29m
2 stops
Avianca Logo
4:00 pm - 9:20 am
CTG
-
LEX
40h 20m
2 stops
$906Avianca
Booking Insights

KAYAK's insights & trends for Lexington to South America flights

Get data-powered insights and trends into flights from Lexington to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Lexington to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Lexington to South America were found on American Airlines ($642) and Delta ($709).

Good to know

Low seasonOctober
Cheapest flight$275
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Lexington to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Lexington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Lexington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Lexington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Lexington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Lexington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Lexington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Lexington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Lexington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Lexington to South America

 
Need help choosing which airline to fly with from Lexington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8296 reviews
7.9Comfort
8.1Boarding
7.2Food
8.5Crew
7.8Entertainment
Airline reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

2.0 MediocreSusan, Mar 2026
JAX - ATL
Read more Delta reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

With Aeromexico it ended up good but with Delta it was bad because we did everything through Delta... Showed up at the Delta terminal... It was the wrong place! Nothing ever told us to go to the Aeromexico terminal. It said "in partnership with Aeromexico" but I was never instructed to check in with them or go to their terminal. We had to haul @$$ running through the airport and almost didn't make it thanks to this poor communication. 👎🏽

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

Everything you need to know for your flight to South America

Information on your arrival and departure airports