$320 Find Cheap Flights from Lexington to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Lexington to South America departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Lexington to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$706
Bogotá
Bogotá1 stop$578
Rio de Janeiro
Rio de Janeiro2 stops$1,155
Santiago
Santiago1 stop$1,144
Cartagena
Cartagena1 stop$751
Quito
Quito2 stops$729
Guayaquil
Guayaquil2 stops$709
Cusco
Cusco2 stops$1,064
Barranquilla
Barranquilla2 stops$662
Lima
Lima2 stops$706
Bogotá
Bogotá1 stop$578
Rio de Janeiro
Rio de Janeiro2 stops$1,155
Santiago
Santiago1 stop$1,144
Cartagena
Cartagena1 stop$751
Quito
Quito2 stops$729
Guayaquil
Guayaquil2 stops$709
Cusco
Cusco2 stops$1,064
Barranquilla
Barranquilla2 stops$662

Book Cheap Lexington to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Lexington to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Lexington to South America

Fri, Nov 28 - Thu, Dec 4
United Airlines Logo
5:45 pm - 10:05 pmLEX-MDE
28h 20m2 stops
United Airlines Logo
1:15 am - 10:30 pmMDE-LEX
21h 15m2 stops
$573United Airlines
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Wed, Jan 14 - Wed, Jan 28
Delta Logo
5:55 am - 7:30 pmLEX-BOG
13h 35m1 stop
Delta Logo
9:00 am - 6:58 pmBOG-LEX
9h 58m1 stop
$578Delta
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Tue, Feb 17 - Tue, Feb 24
LATAM Airlines Logo
7:10 am - 10:40 pmLEX-MDE
15h 30m2 stops
LATAM Airlines Logo
6:00 am - 5:10 pmMDE-LEX
11h 10m2 stops
$595LATAM Airlines
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Sat, Nov 15 - Tue, Nov 18
United Airlines Logo
7:05 am - 10:05 pmLEX-MDE
15h 00m2 stops
United Airlines Logo
10:45 am - 11:44 pmMDE-LEX
12h 59m2 stops
$608United Airlines
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Wed, Jan 14 - Wed, Jan 28
American Airlines Logo
8:05 am - 10:10 pmLEX-BOG
14h 05m2 stops
American Airlines Logo
8:00 am - 11:23 pmBOG-LEX
15h 23m2 stops
$614American Airlines
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Tue, Mar 17 - Mon, Mar 30
LATAM Airlines Logo
7:10 am - 8:15 pmLEX-LIM
14h 05m2 stops
LATAM Airlines Logo
8:50 am - 11:55 pmLIM-LEX
14h 05m2 stops
$724LATAM Airlines
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Wed, Feb 11 - Mon, Feb 16
American Airlines Logo
2:59 pm - 12:55 pmLEX-CTG
21h 56m2 stops
American Airlines Logo
2:50 pm - 10:40 amCTG-LEX
19h 50m2 stops
$763American Airlines
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Sat, Nov 29 - Fri, Dec 5
Multiple Airlines Logo
2:05 pm - 11:35 pmLEX-GYE
33h 30m3 stops
Multiple Airlines Logo
3:30 am - 10:28 amGYE-LEX
30h 58m3 stops
$916Multiple Airlines
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Sat, Nov 29 - Sat, Dec 6
Multiple Airlines Logo
3:53 pm - 3:45 amLEX-EZE
33h 52m3 stops
Multiple Airlines Logo
9:55 pm - 8:32 pmEZE-LEX
24h 37m3 stops
$1,251Multiple Airlines
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Fri, Nov 28 - Thu, Dec 4
Avianca Logo
1:59 pm - 12:40 amLEX-GIG
32h 41m2 stops
Avianca Logo
1:45 am - 8:39 pmGIG-LEX
44h 54m2 stops
$2,097Avianca
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Booking Insights

KAYAK's insights & trends for Lexington to South America flights

Get data-powered insights and trends into flights from Lexington to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Lexington to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Lexington to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Lexington to South America is March, when tickets cost $644 (return) on average. On the other hand, the most expensive months are December and January, when the average cost of round-trip tickets is $1,866 and $1,003 respectively.

Good to know

Low seasonOctober
Cheapest flight$320
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 90% increase in price.
Flight from Lexington to Lima

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Lexington to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Lexington to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Lexington to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Lexington to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Lexington to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Lexington to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Lexington to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Lexington to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the afternoon, when round-trip flights cost $678 on average. Morning departures are around 22% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $1,086.

Reviews of the top 3 airlines serving from Lexington to South America

 
Need help choosing which airline to fly with from Lexington to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7982 reviews
7.9Entertainment
7.3Food
8.2Boarding
8.5Crew
7.9Comfort
Airline reviews

Old plane and old configuration/seats but still comfortable for a morning flight

10.0 ExcellentBraulio, Oct 2025ATL - SDQ
Read more Delta reviews

Old plane and old configuration/seats but still comfortable for a morning flight

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Flight was crowded and the woman sitting on my left was large & kept crouching in to my space. You need bigger seats or smaller passengers to fit into the seats you DO have! Snack were OK. Would appreciate if airlines had more savory rather than sweet snacks, thank you!

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

We were delayed, which I think had to do with air traffic control. Otherwise, everything was great.

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

On time flight. Seat comfort could be better in the Comfort section.

My issue was with TSA agents for delta airlines. My luggage got flagged. The agent was going thru another persons first. He took 20 min to go thru hers. I asked them to bring mine closer so I could sit down . They said you can go sit it will be fine. I said I am supposed to keep my eyes on my bags at all times. The agent was meticulously unwrapping 2 gifts that the lady had and then tried to re warp it. He was trying to be kind i get it but 20 min for me to stand watching him do that was ridiculous. It was 6 am and there were a ton of travelers. Mine was flagged for some air packed tea that I bought in Turkey. My previous delta flight and 2 others before didn’t flag it. Consistency would be nice. Also on the flight the window shades were down for take off and landing - I thought that was very odd I thought they had to remain open for take off and landing.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

Flight attendants on this flight were very attentive and friendly

After we landed we sat on the tarmac for 1.5 hours waiting to get to our gate. Ridiculous.

Food should be better quality. Video screens have poor resolution and the library of movies is poor. The other airlines are much better.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

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