$221 Find Cheap Flights from Louisville to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to Panama departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Louisville to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$415
Panama City
Panama City1 stop$415

Book Cheap Louisville to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to Panama

man., sep. 1 - tir., sep. 9
Delta Logo
6:00 pm - 12:50 pmSDF-PTY
19h 50m1 stop
Delta Logo
2:05 pm - 11:56 pmPTY-SDF
8h 51m1 stop
$415Delta
Find Deal
tor., okt. 2 - tor., okt. 9
American Airlines Logo
6:31 am - 2:31 pmSDF-PTY
9h 00m1 stop
American Airlines Logo
3:15 pm - 12:36 amPTY-SDF
8h 21m1 stop
$423American Airlines
Find Deal
tor., okt. 2 - tor., okt. 9
American Airlines Logo
7:35 pm - 2:31 pmSDF-PTY
19h 56m2 stops
American Airlines Logo
3:15 pm - 1:47 pmPTY-SDF
21h 32m2 stops
$428American Airlines
Find Deal
ons., okt. 8 - lør., okt. 11
United Airlines Logo
7:15 am - 6:37 pmSDF-PTY
12h 22m1 stop
United Airlines Logo
10:00 am - 10:01 amPTY-SDF
23h 01m2 stops
$435United Airlines
Find Deal
tor., sep. 11 - søn., sep. 21
United Airlines Logo
9:40 am - 6:37 pmSDF-PTY
9h 57m1 stop
United Airlines Logo
3:30 pm - 10:02 amPTY-SDF
17h 32m2 stops
$437United Airlines
Find Deal
lør., okt. 4 - lør., okt. 11
United Airlines Logo
8:45 am - 6:37 pmSDF-PTY
10h 52m2 stops
United Airlines Logo
10:00 am - 9:54 pmPTY-SDF
10h 54m1 stop
$444United Airlines
Find Deal
lør., okt. 4 - lør., okt. 11
United Airlines Logo
3:37 pm - 2:14 pmSDF-PTY
23h 37m1 stop
United Airlines Logo
10:00 am - 9:54 pmPTY-SDF
10h 54m1 stop
$448United Airlines
Find Deal
tor., nov. 6 - man., nov. 10
United Airlines Logo
9:15 am - 7:38 pmSDF-PTY
10h 23m1 stop
United Airlines Logo
8:55 am - 9:57 pmPTY-SDF
13h 02m1 stop
$461United Airlines
Find Deal
man., sep. 1 - tir., sep. 9
American Airlines Logo
8:06 pm - 2:30 pmSDF-PTY
19h 24m2 stops
American Airlines Logo
1:45 pm - 11:58 pmPTY-SDF
9h 13m1 stop
$470American Airlines
Find Deal
tor., sep. 11 - søn., sep. 21
United Airlines Logo
7:00 am - 2:14 pmSDF-PTY
8h 14m1 stop
United Airlines Logo
3:30 pm - 10:00 pmPTY-SDF
29h 30m1 stop
$483United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Louisville to Panama flights

Get data-powered insights and trends into flights from Louisville to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Louisville to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Louisville to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Louisville to Panama is September, when tickets cost $416 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $697 and $627 respectively.

What’s the cheapest day of the week to fly from Louisville to Panama?

The average price of all round-trip flights from Louisville to Panama clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama on a Monday, as we generally find the cheapest rates on that day for this route. On the other hand, Thursday is the most expensive day to fly from Louisville to Panama. For your return ticket, we recommend flying on a Wednesday and avoiding Sundays for the best deals.

Good to know

Low seasonNovember
Cheapest flight$188
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 37% increase in price.
Flight from Louisville to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Louisville to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Louisville to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Louisville to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Louisville to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the evening, when round-trip flights cost $365 on average. Morning departures are around 30% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $474.

Reviews of the top 3 airlines serving from Louisville to Panama

 
Need help choosing which airline to fly with from Louisville to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7981 reviews
8.5Crew
7.9Comfort
8.2Boarding
7.9Entertainment
7.3Food
Airline reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

6.0 GoodKristopher, Aug 2025HPN - ATL
Read more Delta reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

There was supposed to be a meal served, but there wasn’t and the major toilet was out of order

It is clear that someone knew, and competent, is in charge of food at United Airlines at least for the international flights. I was flying in coach, but the choices of the dinner were excellent. Tasty, and appropriate size. I had the beef, which was a little bit like a shepherds pie, and it was good. Nothing comparable has been served on a United flight in years. It will not be confused with three star food, but it is very good for airline food. Even better was the breakfast choice between a cinnamon roll and a breakfast sandwich. I chose the breakfast sandwich which was absolutely delicious and which I would happily order again at my local Starbucks or Panera. It is clear that someone knew indifferent is in charge of the food and it’s about time.

The flight was comfortable with the exit row and great service

Had to cancel first flight because Airporter Bus took over 3 hrs to get to airport which resulted in an extra $378 dollar fare . Is there anyway I can be reimbursed for initial fare since it was not my fault? Sent from my iPhone EJ Ledet

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

The pilots were late and it made us 1 hour late. The meat was tough and bok choy was also tough.

Flight was delayed 3 hours. No food and drink vouchers was provided. They offered a mini pretzel bag and water .

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

The service was good, the food could have been better.

Staff was rude. Didn’t give water for 2 hours. Worst service

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

Pretty good. The food was just mediocre, the boarding and crew were good.

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

My flight got switched and my prepaid bag didnt transfer over properly so I paid to check ANOTHER BAG. I was placed in a middle seat and it was just miserable. At least it was a bulkhead row so I had legroom. The flight just never seem3d to end

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

Sat on the ground in Cincinnati for 50 minutes before deplaning

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Everything you need to know for your flight from Louisville to Panama

Information on your arrival and departure airports

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