$471 Find Cheap Flights from Panama to Louisville - Compare and Save
This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Louisville departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
Cheap Flights from Panama to Louisville
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Cheap flights to Louisville from top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.
Mon, Feb 8 - Mon, Feb 22
10:00 am - 7:14 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
9h 14m1 stop Newark
1:00 pm - 8:02 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
31h 02m1 stop Newark
$667United Airlines
Mon, Feb 8 - Mon, Feb 22
10:00 am - 12:15 amPTY Panama City Tocumen Intl-SDF Louisville Intl
14h 15m2 stops Newark Chicago O'Hare Intl
6:00 pm - 5:12 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
23h 12m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$667United Airlines
Mon, Feb 8 - Mon, Feb 22
4:41 pm - 8:19 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
27h 38m1 stop Houston George Bush Intcntl
6:00 pm - 5:12 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
23h 12m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$667United Airlines
Tue, Jan 26 - Fri, Jan 29
11:35 am - 9:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
10h 24m1 stop Houston George Bush Intcntl
7:00 am - 5:12 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
10h 12m1 stop Houston George Bush Intcntl
$693United Airlines
Tue, Jan 26 - Fri, Jan 29
8:55 am - 12:15 amPTY Panama City Tocumen Intl-SDF Louisville Intl
15h 20m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
7:00 am - 7:38 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
12h 38m1 stop Houston George Bush Intcntl
$697United Airlines
Tue, Jan 26 - Fri, Jan 29
8:55 am - 12:15 amPTY Panama City Tocumen Intl-SDF Louisville Intl
15h 20m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
5:43 pm - 5:12 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
23h 29m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$697United Airlines
Mon, Feb 1 - Sat, Feb 6
11:35 am - 9:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
10h 24m1 stop Houston George Bush Intcntl
3:25 pm - 5:12 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
25h 47m1 stop Houston George Bush Intcntl
$705United Airlines
Mon, Feb 1 - Sat, Feb 6
11:35 am - 12:15 amPTY Panama City Tocumen Intl-SDF Louisville Intl
12h 40m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
5:43 pm - 2:45 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
21h 02m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$705United Airlines
Mon, Nov 16 - Thu, Mar 18
3:13 pm - 12:25 amPTY Panama City Tocumen Intl-SDF Louisville Intl
9h 12m1 stop Miami
6:00 am - 2:30 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
9h 30m1 stop Miami
$746American Airlines
Mon, Nov 16 - Thu, Mar 18
3:13 pm - 12:25 amPTY Panama City Tocumen Intl-SDF Louisville Intl
9h 12m1 stop Miami
6:27 pm - 2:30 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
21h 03m2 stops Dallas/Fort Worth Miami
$751American Airlines
Wed, Jan 6
9:48 pm - 8:29 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
22h 41m3 stops Miami Atlanta Hartsfield-Jackson Tampa
$471Multiple Airlines
Wed, Jan 6
12:03 pm - 8:29 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
32h 26m2 stops Fort Lauderdale Tampa
$495Multiple Airlines
Thu, Jan 7
12:03 pm - 3:11 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
27h 08m2 stops Fort Lauderdale Tampa
$499Multiple Airlines
Thu, Jan 7
9:48 pm - 8:51 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
47h 03m3 stops Miami Cincinnati Cinci./N. Kentucky Fort Myers SW Florida Intl
$509Multiple Airlines
Fri, Jan 8
2:26 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
9h 33m1 stop Miami
$523American Airlines
Thu, Jan 7
2:26 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
9h 33m1 stop Miami
$523American Airlines
Tue, Jan 5
4:33 pm - 12:18 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
19h 45m2 stops Miami Charlotte Douglas
$528American Airlines
Fri, Jan 8
4:55 pm - 4:11 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
23h 16m2 stops Miami Washington, D.C. Reagan-National
$528American Airlines
Wed, Jan 6
8:55 am - 1:36 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
28h 41m1 stop Houston George Bush Intcntl
$893United Airlines
Tue, Oct 13 - Tue, Nov 3
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$767Delta
Mon, Oct 12 - Mon, Nov 2
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$767Delta
Mon, Oct 12 - Tue, Nov 3
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$767Delta
Thu, Oct 15 - Thu, Nov 12
3:30 pm - 5:40 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
25h 10m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
7:00 am - 7:38 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
12h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$789United Airlines
Thu, Oct 15 - Thu, Nov 12
9:45 am - 11:41 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
12h 56m1 stop Newark
5:10 am - 7:38 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
14h 28m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$789United Airlines
Mon, Oct 12 - Thu, Nov 5
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$789Delta
Tue, Oct 13 - Wed, Nov 4
2:24 pm - 7:10 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
27h 46m1 stop Atlanta Hartsfield-Jackson
6:00 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
7h 59m1 stop Atlanta Hartsfield-Jackson
$789Delta
Mon, Oct 12 - Mon, Nov 9
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 2:02 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 57m1 stop Atlanta Hartsfield-Jackson
$789Delta
Mon, Oct 12 - Tue, Nov 3
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
7:05 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$789Delta
Mon, Oct 12 - Wed, Nov 4
2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-SDF Louisville Intl
8h 35m1 stop Atlanta Hartsfield-Jackson
6:00 am - 1:59 pmSDF Louisville Intl-PTY Panama City Tocumen Intl
7h 59m1 stop Atlanta Hartsfield-Jackson
$789Delta
KAYAK's insights & trends for flights to Louisville
Get data-powered insights and trends for flights to Louisville to help you find the cheapest flights, the best time to fly and much more.
How long is the flight to Louisville?
The duration of your flight to Louisville depends on your departure and arrival airports. Obviously, any flights that include a layover will also be longer. The most popular route to Louisville on KAYAK is from Panama City, which takes 9h 01m.
How many direct flights to Louisville are there each day?
There are around 256 direct flights from within Panama to Louisville every day. Most flights depart in the afternoon, with 34% of flights departing in the afternoon.
Good to know
Low season | November |
|---|---|
High season | May |
Cheapest flight | $471 |
FAQs - booking Louisville flights
Top tips for finding cheap flights to Louisville
Reviews of the top airline flying from Panama to Louisville
See real verified KAYAK customer reviews for airlines flying to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to Louisville. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
7.4
United AirlinesOverall score based on 10331 reviews
7.1Entertainment
7.3Comfort
7.7Boarding
6.7Food
8.1Crew
Airline reviews
My easiest trip ever. Flights left on time, and came in a few minutes early. The flights weren’t full so it was very comfortable. Thank you United
10.0 ExcellentNancy, Oct 2026
My easiest trip ever. Flights left on time, and came in a few minutes early. The flights weren’t full so it was very comfortable. Thank you United
typical but they have finally enhanced the wifi on some UA flights. Boy, its such a huge improvement
This was a small aircraft (relatively) and we were delayed half an hour on takeoff, which is not the airlines fault.
It was hot and not as comfortable as the flight to Chicago. Must have been a different plane that needs to be worked on or replaced.
It was terrible. sat on airplane 2 hours then flight was canceled. made to pick up bags and go through Panama immagration to rebook another flight. worst experice ever at a airport.
Crew was tired as we all were. Pretty abrupt. Flight was delayed. Not as enjoyable as the other 3 legs we flew.
Good until I was put on air canada flight Houston Vancouver not even one cookie
Short flight, but no drink/snack service. The flights both going and coming were delayed.
More racist flight attandants maybe because i sm an attracticted darkskin latino man but once again bad flight attamdants they ignored me the whole flight even the woman sitting next to me notice how rude they were towards me i really never want to fly united or american airlines they alawsys have the rudesslt and racist flight attandants
The check in from Panama to Houston was good. From Houston to Toronto was definitely an experience. The Pilot from Houston to Toronto was exceptional. He probably saved our lives by noticing a dent in the fuselage. Everyone was taken off the plane and we boarded a new plane
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsFrench Lick
Jeffersonville
West Baden Springs
Elizabeth
Charlestown
Georgetown
Brandenburg
More options for your flight to Louisville
Complete your trip to Louisville with a hotel stay or car rental
Information on the airport you'll fly into in Louisville
Cabin class types available on flights to Louisville
Cabin classes available on flights to Louisville. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Find direct flights for Louisville
Flights from local origins to Louisville
Flights from all regions of Panama to Louisville. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.