PTY - MAD

$435 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Expert advice
Useful Info
Flights Deals

Cheap Flights from Panama City to Madrid

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Madrid

Tue, Jul 22 - Fri, Sep 19
KLM Logo
6:50 pm - 12:05 pmPTY-MAD
34h 15m1 stop
KLM Logo
6:00 am - 4:50 pmMAD-PTY
17h 50m1 stop
$697KLM
Find Deal
Mon, Jun 16 - Sun, Sep 14
 Logo
6:50 pm - 9:35 amPTY-MAD
31h 45m1 stop
 Logo
10:05 am - 5:45 pmMAD-PTY
14h 40m1 stop
Thu, Oct 30 - Sun, Nov 9
Avianca Logo
3:19 am - 10:35 pmPTY-MAD
13h 16m1 stop
Avianca Logo
12:35 am - 9:40 amMAD-PTY
15h 05m1 stop
$721Avianca
Find Deal
Sun, Jul 20 - Sat, Sep 20
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$724Air Europa
Find Deal
Sat, May 31 - Mon, Jun 16
Air France Logo
8:00 am - 9:35 amPTY-MAD
18h 35m1 stop
Air France Logo
5:45 pm - 5:45 pmMAD-PTY
31h 00m1 stop
$738Air France
Find Deal
Sun, Sep 21 - Sat, Oct 4
Air France Logo
7:55 pm - 11:10 pmPTY-MAD
20h 15m1 stop
Air France Logo
6:00 am - 5:45 pmMAD-PTY
18h 45m1 stop
$747Air France
Find Deal
Sat, Jul 19 - Thu, Sep 25
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pmMAD-PTY
10h 35mnonstop
$756Air Europa
Find Deal
Mon, Sep 15 - Fri, Sep 26
Iberia Logo
5:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
Iberia Logo
12:00 pm - 3:40 pmMAD-PTY
10h 40mnonstop
$768Iberia
Find Deal
Fri, Oct 31 - Fri, Nov 7
Avianca Logo
11:25 am - 8:55 amPTY-MAD
15h 30m1 stop
Avianca Logo
12:35 am - 4:30 pmMAD-PTY
21h 55m1 stop
$794Avianca
Find Deal
Sat, Oct 25 - Sat, Nov 15
Iberia Logo
5:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
Iberia Logo
11:45 am - 4:50 pmMAD-PTY
11h 05mnonstop
$800Iberia
Find Deal
Expert advice

Expert advice for your flight from Panama City to Madrid

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers two meal services for premium and business fares, including special dietary options.


Air Europa's SUMA loyalty program offers priority boarding and lounge access at higher tiers.

Iberia

Iberia's business class offers all-aisle access and comfortable seating on long-haul flights.


Iberia provides Wi-Fi with global coverage on most of its network, suitable for basic messaging.

Read more about Iberiaby Marisa Garcia
Airports
PTY

For a smooth departure, check your airline's terminal in advance. Copa Airlines check-in is in Terminal 2, even if your flight departs from Terminal 1.

Read more about PTYby Mark Chesnut
MAD

Upon arrival at MAD, use the metro for a quick, 30-40 minute ride to the city center. A small supplement applies to the standard fare.

Read more about MADby Ramsey Qubein
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on MAD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Useful Info

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Madrid on a Tuesday, as we generally find the cheapest rates on that day for this route. On the other hand, Wednesday is the most expensive day to fly from Panama City to Madrid. For your return ticket, we recommend flying on a Monday and avoiding Tuesdays for the best deals.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is March, where tickets cost $684 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $871 and $865 respectively.

Can I save money by flying with a layover from Panama City to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $1,538 on average.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 5 weeks before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonAugust
High seasonSeptember
Cheapest flight$435
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 0% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was $435 for a one-way ticket and $697 for a round-trip.

  • Do I need a passport to fly between Panama City and Madrid?

    A passport is required to fly from Panama City to Madrid.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    Iberia, Air France, British Airways, Finnair, and Air Europa offer inflight Wi-Fi service on the Panama City to Madrid flight route.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Airbus A330 is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are nonstop flights from Panama City to Madrid on a daily basis.

  • Which is the best airline for flights from Panama City to Madrid, KLM or Air France?

    The two airlines most popular with KAYAK users for flights from Panama City to Madrid are KLM and Air France. With an average price for the route of $801 and an overall rating of 7.8, KLM is the most popular choice. Air France is also a great choice for the route, with an average price of $765 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Panama City with another airline. Booking your flights between Panama City and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $592 or less one-way and $825 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Tuesday

Air Europa, China Eastern, Copa Airlines, +1 more

Air Europa, China Eastern, +2 more

Wednesday

Air Europa, China Eastern, Copa Airlines, +1 more

Air Europa, China Eastern, +2 more

Thursday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Friday

Air Europa, China Eastern, Copa Airlines, +2 more

Air Europa, China Eastern, +3 more

Saturday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Sunday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Tuesday

Air Europa, China Eastern, Copa Airlines, +1 more

Air Europa, China Eastern, +2 more

Wednesday

Air Europa, China Eastern, Copa Airlines, +1 more

Air Europa, China Eastern, +2 more

Thursday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Friday

Air Europa, China Eastern, Copa Airlines, +2 more

Air Europa, China Eastern, +3 more

Saturday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

Sunday

Air Europa, British Airways, China Eastern, +5 more

Air Europa, British Airways, +6 more

See more direct flights
See more direct flights

Top 5 airlines serving from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
Air FranceOverall score based on 1448 reviews
7.0Entertainment
7.4Boarding
7.4Comfort
8.2Crew
7.0Food
Airline reviews

My experience was good overall, the quality of the food really decreased! There used to be a choice between meat and fish now it’s between chicken and pasta! In the choices of entertainment meditation has been added which is very good. Soft chair workout to improve blood circulation and avoid phlebitis should be added.

8.0 ExcellentLamia, Apr 2025CDG - YUL
Read more Air France reviews

My experience was good overall, the quality of the food really decreased! There used to be a choice between meat and fish now it’s between chicken and pasta! In the choices of entertainment meditation has been added which is very good. Soft chair workout to improve blood circulation and avoid phlebitis should be added.

The only reason the overall rating wasn't "excellent" was due to problems in claiming luggage. The bags are delivered to the main area (Cinta 35) for domestic passengers, but to a DIFFERENT ROOM for international arrivees. After waiting 30 minutes, someone (who didn't appear to be from Air France or the airport) told us to go to another area. There we found our bags, which appeared to have been awaiting us for a while. We had to go through a bag check before leaving the airport. If we had been alerted to this possibility, or better yet, been to go directly to Cinta 34, we could have eliminated quite a bit of waiting.

Much better than the major US Carriers especially in Biz Class.

I wish that the meal included a vegetable or even a salad instead of couscous! Why serve chicken with rice AND couscous? Service was good overall though a bit lacking in friendliness. Usually on air france I've been offered a glass of champagne before dinner, wine with dinner, and a digestif after dinner. We were only offered wine this time!

It was not Air France but Air Europa. But confusion over our checked luggage. Whether it was checked all the way to Tenerife or not. It was not. Had to line up again in Departures. At least our Sky Priority was honoured. Flight was fine.

My wife and I had a row to ourselves after moving seats. There were no TVs and you had to buy food. So we did nothing but had a quick nap. Flight was fine.

The male attended that served are section was a snob. He did not answer my call light when my wine spilled all over the floor. I did not push it again or drew his attention to it. He just ignored the call light when he came to give us our meal, serving the people behind us first. I did not push it again or drew his attention to it to see his reaction. It was so obvious that he was ignoring us. We were in premium economy!

The plane was old Only 3 bathrooms available for economy The entertainment was old and the selection was poor

Georgian Airways check in staff initially denied us, because they thought passengers required transit visas to transfer on connecting flights. This required 70 minutes for them to call multiple people to confirm how transfers worked. They did not apologize once accepting our check in. Onboard, the four hour flight gave stale bread with spam slices as lunch. The only included drinks were still or sparkling water.

I did not get my baggage at my final destination..poor coordination with connecting flights with partner airlines (Saudi airways). Also the food was very mediocre.

Compared with other carriers business class for an overnight was not worth the extra expense.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

The ANA crew and their members were all extremely nice and caring. Shout out to the crews for working on Christmas and New Years. Y'all the real MVP

The fight didn’t happen because I was rerouted to Trinidad as previously explained.

First class felt like economy, seats were horrible, food was horrible, staff inattentive

Sucks ! All three flights I was on this trip were delayed.

The plane’s radio wasn’t working. This delayed the plane for an hour and a half. Then we all broaded and taxied down the runway only to get called back because the radio was still not working. Had to get off the plane and then find another plane making the trip 4 hours delayed. Maybe a different plane should have been chosen sooner?!?!?!

I was not aware that I have to pay for the checked bag on the return flight. It was included in the price when I bought the ticket

Flight from Costa Rica to Madrid was excellent. Good food and service. The flight from Madrid to Brussels was very poor . No food , no entertainment, no usb … Total package was quite expensive so you should give same service on the second flight

business class food was pretty average otherwise it was a good experience

Flight from Madrid to Dakar had no onboard entertainment for a business class. Not even a single screen . That was disappointing. The WiFi only worked for the first 45 mins of the flight.

I paid to upgrade to Business Class. The queue to check in at the Business Class aisle was full of people without Business Class tickets, the fast-track immigration line was “closed” but the representative opened it up for his friends, regardless (there was a lot of fist-bumping), and the lounge was an absolute mess…..4 staff sitting playing with their phones while every table had dirty plates and glasses waiting to be cleared…..and the least said about the rude lady on the reception desk at the lounge , the better!

Horrible. Paid for seats for my family. Iberia changed planes and never notified us that the seats we paid extra for did not even exist on the plane. We were randomly placed on the plane. Thankfully, we were seated together. Upon boarding, my youngest daughter was pulled from the line and they just arbitrarily changed her seat 7 rows back from the rest of the family. I had to wait at the gate while they tried to see us back together. One of the most uncomfortable small spaces on a plane I’ve ever experienced. When I called Iberia, they first told me that no mistake was made that the plane was never changed. Yet my receipt for my paid seats were for rows that did not even exist on this type of plane we were getting on. They said that they would reimburse my money and I would get an email, but I’ve never received any information or emails regarding a refund for the seats that I had paid extra for. Then when we arrived in Madrid, one of the pieces of luggage that we had checked in was damaged to the point that the handle that was stowed in to the luggage was broken off by the crew members handling the luggage. The crew on the plane was very nice, but as far as the rest of the experience, I would be very hesitant to ever use Iberia again.

Bad business class. Staff totally not helping. Lights and chargers not working

The flight left Tanger two hours late and I missed my flight to Geneva.

This was such a bad experience. Iberia in Paris Orly refused to issue the boarding pass for my connecting international flight. They were evasive but said it would be dealt with in Madrid. In Madrid there was no help, no transit desk, I almost missed the flight trying to get the boarding pass and only at the gate they told me they had downgraded me. I really felt abused.

The connection required us to travel from terminal A to terminal E with very little time in between flights. While waiting in line, we were called to the service desk to provide our passports. We provided our passports at time of check in, assuming that American Airlines doesn’t communicate well with Iberia, this was a headache.

Almost great...Need more signs around the airport, especially in Italy Marco Polo.

I flew business class, at breakfast I asked for a small bottle of olive oil instead of butter and the flight attendant responded with a negative gesture.

They didn't even give us water, everything was sold

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

They gave me an upgrade but charged me for my bag. I felt abused because this had never happened to me before with an upgrade with another airline.

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

All flights with Air Europa you arrive late to the connections of other flights, I missed my train, I had to pay for my train again, the crew are antisocial, you are paying for a service, it is not free, thanks to the travelers they are there, it is the last time I fly with them,

Terrible experience - we won’t be flying with Air Europa again

The crew was not kind , just doing their job but very cold people

The insanely long lines at customs were chaotic and stressful. They also created a lot of stress among passengers. Including fights and threats. The hot food I purchased was cold, barely edible. The check in staff and crew were nice and the pilot good but the overall experience was very disappointing. Passengers were still insulting each other upon arrival.

No frills airlines. Tickets were reasonably priced for a short-term booking. But comfort is a big issue.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

please see previous response; it covers the whole travel trajectory.

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.