PTY - MAD

$436 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
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Everything you should know

Cheapest round-trip
$699
Overall average: $711
Iberia
Wed 2/11Wed 3/18
PTY - MAD • Non-stop
Cheapest one-way
$436
Typical prices: $555-$660
Multiple Airlines
Sat 2/28
PTY - MAD • 2 stops
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia provides Wi-Fi for basic messaging on flights.
Use the metro line from Madrid Barajas to the city.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Iberia
Cheapest • from $699 (round-trip)
Air France
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 10% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Madrid

Wed, Feb 11 - Wed, Mar 18
Iberia Logo
6:20 pm - 10:25 am
PTY
-
MAD
10h 05mnonstop
Iberia Logo
11:40 am - 4:45 pm
MAD
-
PTY
11h 05mnonstop
$699Iberia
Thu, Feb 5 - Fri, Feb 20
Avianca Logo
2:55 am - 11:20 pm
PTY
-
MAD
14h 25m1 stop
Avianca Logo
4:20 pm - 12:40 am
MAD
-
PTY
14h 20m1 stop
$700Avianca
Wed, Feb 4 - Wed, Feb 18
Multiple Airlines Logo
10:05 pm - 10:15 am
PTY
-
MAD
30h 10m1 stop
Multiple Airlines Logo
6:00 am - 8:10 pm
MAD
-
PTY
20h 10m1 stop
$702Multiple Airlines
Wed, Feb 4 - Wed, Feb 18
Multiple Airlines Logo
10:05 pm - 10:15 am
PTY
-
MAD
30h 10m1 stop
Multiple Airlines Logo
6:00 am - 8:10 pm
MAD
-
PTY
20h 10m1 stop
$706Multiple Airlines
Wed, Feb 4 - Thu, Feb 26
KLM Logo
10:05 pm - 10:15 am
PTY
-
MAD
30h 10m1 stop
KLM Logo
6:00 am - 4:30 pm
MAD
-
PTY
16h 30m1 stop
$711KLM
Wed, Feb 4 - Wed, Feb 18
Multiple Airlines Logo
10:05 pm - 10:15 am
PTY
-
MAD
30h 10m1 stop
Multiple Airlines Logo
6:00 am - 8:10 pm
MAD
-
PTY
20h 10m1 stop
$713Multiple Airlines
Wed, Feb 4 - Wed, Mar 11
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
$714Air Europa
Thu, Feb 5 - Fri, Feb 13
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
$716Air Europa
Wed, Feb 11 - Thu, Feb 26
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
$722Air Europa
Fri, Feb 13 - Fri, Feb 27
Avianca Logo
5:50 pm - 11:20 pm
PTY
-
MAD
23h 30m1 stop
Avianca Logo
4:20 pm - 12:40 am
MAD
-
PTY
14h 20m1 stop
$723Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Madrid on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Panama City to Madrid. For your return ticket, we recommend flying on a Wednesday and avoiding Thursdays for the best deals.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is March, where tickets cost $702 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $915 and $878 respectively.

Can I save money by flying with a layover from Panama City to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $863, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 7 weeks before departure, which saves you about 16% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers two meal services for premium and business fares, including special dietary options.


Air Europa's SUMA loyalty program offers priority boarding and lounge access at higher tiers.

Iberia

Iberia's business class offers all-aisle access and comfortable seating on long-haul flights.


Iberia provides Wi-Fi with global coverage on most of its network, suitable for basic messaging.

Airports
PTY

For a smooth departure from PTY, determine your terminal in advance. Copa Airlines check-in is in Terminal 2, even if your flight departs from Terminal 1.

MAD

Upon arrival at MAD, use the metro line for a quick, 30-40 minute ride to the city center. A small supplement applies to the standard fare.

Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on MAD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more

Good to know

Low seasonJuly
Cheapest flight$436
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was $436 for a one-way ticket and $699 for a round-trip.

  • Do I need a passport to fly between Panama City and Madrid?

    A passport is required to fly from Panama City to Madrid.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    Iberia, Copa Airlines, Air France, British Airways, and Finnair offer inflight Wi-Fi service on the Panama City to Madrid flight route.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are nonstop flights from Panama City to Madrid on a daily basis.

  • Which is the best airline for flights from Panama City to Madrid, KLM or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Madrid are KLM and Copa Airlines. With an average price for the route of $776 and an overall rating of 7.7, KLM is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $1,260 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Panama City with another airline. Booking your flights between Panama City and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $624 or less one-way and $826 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Reviews of the top 5 airlines serving from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
Air FranceOverall score based on 1500 reviews
7.4Boarding
7.0Food
7.3Comfort
7.0Entertainment
8.2Crew
Airline reviews

Food was really mediocre for premium economy in comparison to other airlines… the crew was nowhere to be found… 14 hour flight…

6.0 GoodShalom, Nov 2025
SCL - CDG
Read more Air France reviews

Food was really mediocre for premium economy in comparison to other airlines… the crew was nowhere to be found… 14 hour flight…

I don’t like that an equipment change caused my seat to change from 23A to 44A. The boarding was also delayed. The crew were excellent, however and very attentive. The food was not bad.

3 hour delay but out of their control. App said I get vouchers but when I applied for them, they were nowhere to be found in my account

I bought business class tickets but the seats are exactly like economy with no comfort seats nor an empty seat next to me provided. Very poor, low quality airline.

I don't understand the concept of paying to get your personal luggage onboard and then asked to check it in.... either sell the space or don't, its a hassle to carry those all through the airport just to make a check in at the last minute.

The food was great and the service and attitude was amazing!!

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

It was an OK flight with below mediocre service by their flight attendants

Wasted a lot of time trying to find the CDG lounge - it was not next to the connecting flight gate like the Air France staff said.

Excellent food and service on my international flight. Most notable is the food provided by Turkish even for coach passengers is very good.

Very bad this airline changes my schedule date of travel and get me stranded in Istanbul for three days, paid for only one day hotel accommodation with only one breakfast and i had to pay for lunches ,and dinners and hotel accommodations for the two and half days

They can my date of travel and let me standard in Istanbul for three days stop over and only pay for one day in a hotel with only one breakfast for three days.

They changed the return flight to the next day and it interrupted the plans we had in our connecting city.

My flight was canceled 1 minute before boarding. The customer service was owful, no one could tell us what was going happened. I spent 30hrs instead of 15 from Washington DC to Brussels. No apologie or help

Boarded via bus instead of the air bridge Had to wait 10mins in the bus at the tarmac before we were allow to go up

It was pleasant except for the boarding at Istanbul and long wait for the wheel chair almost missed the flight Itambul to Dubai

During mid flight, try to get a flight attendant to help I couldn’t find one Otherwise, everything was perfect

It was ok. Not the experience I expected from Turkish airlines

Both my luggages were never sent from Istanbul. After 10 hour flight from DC to Turkey and another 12 hour layover in Istanbul Airport, I would’ve at least expected to find my luggages when I arrived in Addis Ababa, but that wasn’t the case. After 2 hours of waiting at the luggage carousel, we were told that our luggages would be arriving the next day after midnight. I was already so exhausted, that I hated having to come back to the airport the next day. Thankfully, I received both my luggages the following day. It’s just, the whole experience was exhausting.

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Need to pay for headsets, water, or any extra except air to breath.

Sitting space was very tight and I am not big or fat (I am 5'10" 178 Lb), so eating was very challenging. The rest was good.

Sitting space was very tight, so eating was difficult. But everything else was good.

12 hours flight. Only one meal, not enough food. At the galley only water during the flight. Lavatories not clean. Headsets at extra cost.

Need to pay for a cup of water. No food. Need to pay for headsets.

Everything should improve! Service like a low cost but prices like a premium airline. Crew in general with bad manners arguing for everything. You pay for priority access but then they use buses, so your loose your advantage to put your carry on first. That was the purpose for paying for priority. Bording is a nightmare, people accessing the plane for bothering doors, front and rear, no matter which line do you have.

The staff was very nice and helpful. Some of the best crew I have met.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

Excellent. Thanks to United Star Alliance, since economy was overbooked, I’m grateful to have been upgraded to Business Class.

Good plane, excellent food, crew and entertainment. Seats in business could use an upgrade

Disaster. Downgraded. Zero apology. No effort or coordination between gate and crew. Awful seat blocked by door emergency slide box. Iberia is a mess. App never works. Avoid this airline.

We departed late but made up most of the time in flight. Our ticket was pure economy, so it wasn’t anything fancy; however, I heard that we arrived in Madrid at the exact same time that First Class passengers arrived! Overall, our experience was similar to what we had on other American Airlines transatlantic flights - good value at a reasonable price. We were even able to get our carry-on baggage onto the plane without needing to gate check it.

Flight was OK. Waiting for luggage in Madrid for 55 minutes, unacceptable

Transportation from gate to airplane was poor we stayed in hot bus for 20 minute no vantilation

The crew were friendly and helpful. Iberia lost our luggage on arrival, Friday and we didn't get it until Sunday at 10:00 p.m. local Malaga time. I also paid $382.80 for seat assignments but two out out of the four were not together. Iberia mentioned that it was because the plane was delayed in Madrid before our flight began in LAX. They should compensate us half of my payment.

We liked the flight but while we purchased an aisle seat, our seats had a different configuration on this flight. A fellow passenger suggested that the airplane had been changed. Too bad we were not informed and had no chance to modify our seat preferences. We were stuck in the window and middle seats with no chance to walk around and go to the bathroom without disturbing our sleeping fellow passenger.

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Boarding, crew were excellent, food was ok and entertainment need to improve

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

Avianca is not what it used to be. So disappointing

why did we have to go through security mid flight

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports