PTY - MAD

$553 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
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Everything you should know

Cheapest round-trip
$669
Overall average: $714
Avianca
Fri 2/6Fri 2/20
PTY - MAD • 1 stop
Cheapest non-stop
$698
Typical prices: $646-$779
Iberia
Wed 3/4Wed 3/18
PTY - MAD • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia provides Wi-Fi for basic messaging on flights.
Use the metro line from Madrid Barajas to the city.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Air Europa
Cheapest • from $720 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 18% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
February
Cheapest • 9% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Madrid

Fri, Feb 6 - Fri, Feb 20
Avianca Logo
5:50 pm - 1:25 pm
PTY
-
MAD
13h 35m
1 stop
Avianca Logo
10:50 am - 8:50 am
MAD
-
PTY
28h 00m
1 stop
$669Avianca
Tue, May 5 - Tue, May 19
Multiple Airlines Logo
2:20 pm - 12:15 pm
PTY
-
MAD
14h 55m
1 stop
Multiple Airlines Logo
8:30 pm - 4:50 pm
MAD
-
PTY
27h 20m
1 stop
$684Multiple Airlines
Fri, May 22 - Mon, Jun 1
Multiple Airlines Logo
6:50 pm - 1:40 pm
PTY
-
MAD
35h 50m
1 stop
Multiple Airlines Logo
6:00 am - 7:45 pm
MAD
-
PTY
20h 45m
1 stop
$691Multiple Airlines
Wed, Feb 4 - Wed, Feb 18
KLM Logo
10:05 pm - 10:15 am
PTY
-
MAD
30h 10m
1 stop
KLM Logo
1:05 pm - 4:30 pm
MAD
-
PTY
33h 25m
1 stop
$696KLM
Wed, Apr 29 - Sun, May 24
Turkish Airlines Logo
10:20 pm - 1:35 pm
PTY
-
MAD
32h 15m
1 stop
Turkish Airlines Logo
2:40 pm - 8:25 pm
MAD
-
PTY
36h 45m
1 stop
$698Turkish Airlines
Mon, Apr 6 - Thu, Apr 16
Avianca Logo
3:25 am - 7:40 am
PTY
-
MAD
21h 15m
1 stop
Avianca Logo
9:40 am - 4:30 pm
MAD
-
PTY
13h 50m
1 stop
$700Avianca
Mon, Feb 23 - Sun, Mar 22
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
$702Air Europa
Wed, Feb 4 - Wed, Feb 18
KLM Logo
6:45 pm - 4:05 pm
PTY
-
MAD
15h 20m
1 stop
KLM Logo
11:00 am - 4:30 pm
MAD
-
PTY
35h 30m
1 stop
$704KLM
Wed, Apr 29 - Sun, May 10
Turkish Airlines Logo
10:20 pm - 1:35 pm
PTY
-
MAD
32h 15m
1 stop
Turkish Airlines Logo
6:25 pm - 8:25 pm
MAD
-
PTY
33h 00m
1 stop
$706Turkish Airlines
Thu, Apr 9 - Wed, Apr 15
Air Europa Logo
8:25 pm - 1:15 pm
PTY
-
MAD
9h 50mnonstop
Air Europa Logo
3:05 pm - 6:40 pm
MAD
-
PTY
10h 35mnonstop
$708Air Europa
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Madrid on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Panama City to Madrid. For your return ticket, we recommend flying on a Wednesday and avoiding Thursdays for the best deals.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is February, where tickets cost $714 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $937 and $882 respectively.

Can I save money by flying with a layover from Panama City to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $789, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 6 weeks before departure, which saves you about 18% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers two meal services for premium and business fares, including special dietary options.


Air Europa's SUMA loyalty program offers priority boarding and lounge access at higher tiers.

Iberia

Iberia's business class offers all-aisle access and comfortable seating on long-haul flights.


Iberia provides Wi-Fi with global coverage on most of its network, suitable for basic messaging.

Airports
PTY

For a smooth departure from PTY, determine your terminal in advance. Copa Airlines check-in is in Terminal 2, even if your flight departs from Terminal 1.

MAD

Upon arrival at MAD, use the metro line for a quick, 30-40 minute ride to the city center. A small supplement applies to the standard fare.

Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on MAD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more

Good to know

Low seasonJuly
Cheapest flight$553
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was $553 for a one-way ticket and $669 for a round-trip.

  • Do I need a passport to fly between Panama City and Madrid?

    A passport is required to fly from Panama City to Madrid.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    Iberia, Copa Airlines, Air France, British Airways, and Finnair offer inflight Wi-Fi service on the Panama City to Madrid flight route.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are nonstop flights from Panama City to Madrid on a daily basis.

  • Which is the best airline for flights from Panama City to Madrid, KLM or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Madrid are KLM and Copa Airlines. With an average price for the route of $762 and an overall rating of 7.7, KLM is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $1,280 and an overall rating of 7.6.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Panama City with another airline. Booking your flights between Panama City and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $636 or less one-way and $789 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Reviews of the top 5 airlines serving from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1559 reviews
8.1Crew
6.8Food
6.8Entertainment
7.8Boarding
7.4Comfort
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Communication on the delay, rebooking and how to get a hotel was poor. Mails, airport check-in and transfer desk said different things.

Food was really mediocre for premium economy in comparison to other airlines… the crew was nowhere to be found… 14 hour flight…

I don’t like that an equipment change caused my seat to change from 23A to 44A. The boarding was also delayed. The crew were excellent, however and very attentive. The food was not bad.

3 hour delay but out of their control. App said I get vouchers but when I applied for them, they were nowhere to be found in my account

I bought business class tickets but the seats are exactly like economy with no comfort seats nor an empty seat next to me provided. Very poor, low quality airline.

I don't understand the concept of paying to get your personal luggage onboard and then asked to check it in.... either sell the space or don't, its a hassle to carry those all through the airport just to make a check in at the last minute.

The food was great and the service and attitude was amazing!!

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

It was an OK flight with below mediocre service by their flight attendants

It was fine, older plane with limited entertainment, otherwise fine.

the seats were so cramped you could barely move. it was difficult to eat when passengers would recline their seats. the seats were so flimsy and unstable that whenever someone got in and out of their seat, it bounced like a spring back in your face. the movies were nice. the food was terrible. even though the conditions were terrible, they tried to pressure passengers to relocate their seats to accommodate adults who were related and wanted to sit next to each other, even after the passengers expressed that they did not want to move for that purpose. on the connecting flight, the “service” consisted of items for purchase. even though the flight was only 45 minutes, once again passengers (including me) were pressured to relocate for people to sit next to each other. they couldn’t be apart for 45 minutes? this was much less compelling than being apart for an 8 hour flight.

Everything went smoothly, and we even arrived 40min earlier than scheduled, on an Orland-Madrid route.

The staff was very nice and helpful. Some of the best crew I have met.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

Excellent. Thanks to United Star Alliance, since economy was overbooked, I’m grateful to have been upgraded to Business Class.

Good plane, excellent food, crew and entertainment. Seats in business could use an upgrade

Disaster. Downgraded. Zero apology. No effort or coordination between gate and crew. Awful seat blocked by door emergency slide box. Iberia is a mess. App never works. Avoid this airline.

We departed late but made up most of the time in flight. Our ticket was pure economy, so it wasn’t anything fancy; however, I heard that we arrived in Madrid at the exact same time that First Class passengers arrived! Overall, our experience was similar to what we had on other American Airlines transatlantic flights - good value at a reasonable price. We were even able to get our carry-on baggage onto the plane without needing to gate check it.

Flight was OK. Waiting for luggage in Madrid for 55 minutes, unacceptable

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Boarding, crew were excellent, food was ok and entertainment need to improve

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports