PTY - MAD

$491 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
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Everything you should know

Cheapest round-trip
$662
Typical prices: $656-$790
Multiple Airlines
Wed 2/11Tue 3/3
PTY - MAD • 1 stop
Cheapest non-stop
$716
Typical prices: $667-$840
Air Europa
Wed 4/22Wed 4/29
PTY - MAD • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia provides Wi-Fi for basic messaging on flights.
Use the metro line from Madrid Barajas to the city.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Air France
Cheapest • from $664 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 9% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Madrid

Wed, Feb 11 - Tue, Mar 3
Multiple Airlines Logo
6:45 pm - 4:05 pm
PTY
-
MAD
15h 20m
1 stop
Multiple Airlines Logo
6:00 am - 8:10 pm
MAD
-
PTY
20h 10m
1 stop
$662Multiple Airlines
Wed, Feb 11 - Wed, Feb 25
Multiple Airlines Logo
6:45 pm - 4:05 pm
PTY
-
MAD
15h 20m
1 stop
Multiple Airlines Logo
6:00 am - 8:10 pm
MAD
-
PTY
20h 10m
1 stop
$663Multiple Airlines
Thu, Apr 16 - Thu, May 7
Air France Logo
2:27 pm - 12:15 pm
PTY
-
MAD
14h 48m
1 stop
Air France Logo
6:00 am - 4:50 pm
MAD
-
PTY
17h 50m
2 stops
$664Air France
Wed, Jun 3 - Tue, Jun 16
KLM Logo
6:50 pm - 1:40 pm
PTY
-
MAD
35h 50m
1 stop
KLM Logo
6:00 am - 4:50 pm
MAD
-
PTY
17h 50m
1 stop
$666KLM
Wed, Feb 11 - Tue, Feb 24
Multiple Airlines Logo
6:45 pm - 4:05 pm
PTY
-
MAD
15h 20m
1 stop
Multiple Airlines Logo
6:45 pm - 8:10 pm
MAD
-
PTY
31h 25m
1 stop
$667Multiple Airlines
Wed, Apr 1 - Sat, Apr 11
Multiple Airlines Logo
2:28 pm - 12:15 pm
PTY
-
MAD
14h 47m
1 stop
Multiple Airlines Logo
8:30 pm - 4:50 pm
MAD
-
PTY
27h 20m
1 stop
$672Multiple Airlines
Wed, Feb 11 - Mon, Mar 2
Multiple Airlines Logo
6:45 pm - 4:05 pm
PTY
-
MAD
15h 20m
1 stop
Multiple Airlines Logo
6:45 pm - 8:10 pm
MAD
-
PTY
31h 25m
1 stop
$675Multiple Airlines
Thu, Apr 9 - Thu, Apr 16
Air France Logo
2:28 pm - 12:15 pm
PTY
-
MAD
14h 47m
1 stop
Air France Logo
6:00 am - 4:50 pm
MAD
-
PTY
17h 50m
2 stops
$681Air France
Wed, Jun 3 - Tue, Jun 16
Multiple Airlines Logo
6:50 pm - 1:40 pm
PTY
-
MAD
35h 50m
1 stop
Multiple Airlines Logo
6:00 am - 4:50 pm
MAD
-
PTY
17h 50m
2 stops
$687Multiple Airlines
Wed, Apr 22 - Sat, May 9
Multiple Airlines Logo
2:27 pm - 12:15 pm
PTY
-
MAD
14h 48m
1 stop
Multiple Airlines Logo
8:30 pm - 4:50 pm
MAD
-
PTY
27h 20m
1 stop
$689Multiple Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Madrid?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Madrid departing in February.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Madrid on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Panama City to Madrid. For your return ticket, we recommend flying on a Wednesday and avoiding Thursdays for the best deals.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is May, where tickets cost $714 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $936 and $887 respectively.

Can I save money by flying with a layover from Panama City to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $784 on average.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 6 weeks before departure, which saves you about 17% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Ramsey Qubein

Ramsey Qubein

Expert on MAD

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonJuly
Cheapest flight$491
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was $491 for a one-way ticket and $662 for a round-trip.

  • Do I need a passport to fly between Panama City and Madrid?

    A passport is required to fly from Panama City to Madrid.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    All the following airlines offer inflight Wi-Fi service on the Panama City to Madrid flight route: Iberia, Copa Airlines, Air France, Air Europa, British Airways, and Finnair.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are nonstop flights from Panama City to Madrid on a daily basis.

  • Which is the best airline for flights from Panama City to Madrid, KLM or Copa Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Madrid are KLM and Copa Airlines. With an average price for the route of $763 and an overall rating of 7.7, KLM is the most popular choice. Copa Airlines is also a great choice for the route, with an average price of $1,280 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Panama City with another airline. Booking your flights between Panama City and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $811 or less one-way and $726 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa, Iberia

Air Europa, Iberia

See more direct flights

Reviews of the top 5 airlines serving from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1560 reviews
7.4Comfort
8.1Crew
6.8Entertainment
6.8Food
7.8Boarding
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Communication on the delay, rebooking and how to get a hotel was poor. Mails, airport check-in and transfer desk said different things.

Food was really mediocre for premium economy in comparison to other airlines… the crew was nowhere to be found… 14 hour flight…

I don’t like that an equipment change caused my seat to change from 23A to 44A. The boarding was also delayed. The crew were excellent, however and very attentive. The food was not bad.

3 hour delay but out of their control. App said I get vouchers but when I applied for them, they were nowhere to be found in my account

I bought business class tickets but the seats are exactly like economy with no comfort seats nor an empty seat next to me provided. Very poor, low quality airline.

I don't understand the concept of paying to get your personal luggage onboard and then asked to check it in.... either sell the space or don't, its a hassle to carry those all through the airport just to make a check in at the last minute.

The food was great and the service and attitude was amazing!!

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

It was an OK flight with below mediocre service by their flight attendants

The pilot was professional and very good. The flight crew, very young and often looked flustered and overwhelmed. The seats were among the most uncomfortable in the air. The boarding somewhat chaotic. The price reasonable. Overall it was an average budget airline experience...although Iberia is not a budget airline. I fear if Iberia doesn't up it's game customers like us will go elsewhere.

It was fine, older plane with limited entertainment, otherwise fine.

the seats were so cramped you could barely move. it was difficult to eat when passengers would recline their seats. the seats were so flimsy and unstable that whenever someone got in and out of their seat, it bounced like a spring back in your face. the movies were nice. the food was terrible. even though the conditions were terrible, they tried to pressure passengers to relocate their seats to accommodate adults who were related and wanted to sit next to each other, even after the passengers expressed that they did not want to move for that purpose. on the connecting flight, the “service” consisted of items for purchase. even though the flight was only 45 minutes, once again passengers (including me) were pressured to relocate for people to sit next to each other. they couldn’t be apart for 45 minutes? this was much less compelling than being apart for an 8 hour flight.

Everything went smoothly, and we even arrived 40min earlier than scheduled, on an Orland-Madrid route.

The staff was very nice and helpful. Some of the best crew I have met.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

Excellent. Thanks to United Star Alliance, since economy was overbooked, I’m grateful to have been upgraded to Business Class.

Good plane, excellent food, crew and entertainment. Seats in business could use an upgrade

Disaster. Downgraded. Zero apology. No effort or coordination between gate and crew. Awful seat blocked by door emergency slide box. Iberia is a mess. App never works. Avoid this airline.

We departed late but made up most of the time in flight. Our ticket was pure economy, so it wasn’t anything fancy; however, I heard that we arrived in Madrid at the exact same time that First Class passengers arrived! Overall, our experience was similar to what we had on other American Airlines transatlantic flights - good value at a reasonable price. We were even able to get our carry-on baggage onto the plane without needing to gate check it.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports