PTY - MAD

$423 Find Cheap Flights from Panama City to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Madrid departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Madrid.
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Flight Deals

Cheap Flights from Panama City to Madrid (PTY-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Madrid

Sun, Nov 2 - Sun, Nov 23
Air Europa Logo
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
$666Air Europa
Find Deal
Sun, Sep 28 - Sun, Nov 2
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
$669Air Europa
Find Deal
Fri, Oct 31 - Mon, Nov 10
Avianca Logo
5:55 pm - 1:25 pmPTY-MAD
13h 30m1 stop
Avianca Logo
6:35 am - 2:00 pmMAD-PTY
13h 25m1 stop
$689Avianca
Find Deal
Sun, Nov 2 - Fri, Nov 14
Avianca Logo
5:55 pm - 1:25 pmPTY-MAD
13h 30m1 stop
Avianca Logo
1:20 am - 8:50 amMAD-PTY
13h 30m1 stop
$690Avianca
Find Deal
Tue, Dec 9 - Sat, Jan 10
 Logo
10:20 pm - 7:10 pmPTY-MAD
14h 50m1 stop
 Logo
11:00 am - 7:55 pmMAD-PTY
14h 55m1 stop
Sun, Sep 21 - Sat, Oct 4
Turkish Airlines Logo
9:55 pm - 4:50 pmPTY-MAD
35h 55m1 stop
Turkish Airlines Logo
6:20 pm - 8:00 pmMAD-PTY
32h 40m1 stop
$719Turkish Airlines
Find Deal
Tue, Dec 9 - Fri, Jan 9
 Logo
10:20 pm - 11:05 pmPTY-MAD
18h 45m1 stop
 Logo
4:50 pm - 7:55 pmMAD-PTY
33h 05m1 stop
Wed, Feb 4 - Wed, Feb 18
Iberia Logo
6:20 pm - 10:25 amPTY-MAD
10h 05mnonstop
Iberia Logo
11:40 am - 4:45 pmMAD-PTY
11h 05mnonstop
$725Iberia
Find Deal
Mon, Nov 3 - Tue, Nov 18
Turkish Airlines Logo
9:45 pm - 10:25 amPTY-MAD
30h 40m1 stop
Turkish Airlines Logo
5:55 pm - 7:50 pmMAD-PTY
31h 55m1 stop
$741Turkish Airlines
Find Deal
Mon, Oct 6 - Thu, Oct 23
Iberia Logo
5:10 pm - 10:15 amPTY-MAD
10h 05mnonstop
Iberia Logo
12:00 pm - 3:40 pmMAD-PTY
10h 40mnonstop
$757Iberia
Find Deal
Expert advice

Expert advice for your flight from Panama City to Madrid

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers two meal services for premium and business fares, including special dietary options.


Air Europa's SUMA loyalty program offers priority boarding and lounge access at higher tiers.

Iberia

Iberia's business class offers all-aisle access and comfortable seating on long-haul flights.


Iberia provides Wi-Fi with global coverage on most of its network, suitable for basic messaging.

Read more about Iberiaby Marisa Garcia
Airports
PTY

For a smooth departure from PTY, determine your terminal in advance. Copa Airlines check-in is in Terminal 2, even if your flight departs from Terminal 1.

Read more about PTYby Mark Chesnut
MAD

Upon arrival at MAD, use the metro line for a quick, 30-40 minute ride to the city center. A small supplement applies to the standard fare.

Read more about MADby Ramsey Qubein
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on MAD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Booking Insights

KAYAK's insights & trends for Panama City to Madrid flights

Get data-powered insights and trends into flights from Panama City to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Madrid?

The average price of all round-trip flights from Panama City to Madrid clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Madrid on a Tuesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Panama City to Madrid. For your return ticket, we recommend flying on a Wednesday and avoiding Thursdays for the best deals.

What is the cheapest month to fly from Panama City to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Madrid is March, where tickets cost $690 (return) on average. On the other hand, the most expensive months are July and August, where the average cost of round-trip tickets is $879 and $864 respectively.

Can I save money by flying with a layover from Panama City to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $1,487 on average.

How far in advance should I book a flight from Panama City to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Madrid, you should book around 7 weeks before departure, which saves you about 15% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Good to know

Low seasonJuly
Cheapest flight$423
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Madrid

When to book flights from Panama City to Madrid

Are your dates flexible? Find out the best times to travel from Panama City to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Madrid

  • What is the cheapest flight from Panama City to Madrid?

    In the last 3 days, the lowest price for a flight from Panama City to Madrid was $423 for a one-way ticket and $666 for a round-trip.

  • Do I need a passport to fly between Panama City and Madrid?

    A passport is required to fly from Panama City to Madrid.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Madrid?

    Iberia, Copa Airlines, Air France, Finnair, and British Airways offer inflight Wi-Fi service on the Panama City to Madrid flight route.

  • Which aircraft models fly most regularly from Panama City to Madrid?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Panama City to Madrid flight route.

  • Which airline alliances offer flights from Panama City to Madrid?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Madrid, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Madrid?

    There are nonstop flights from Panama City to Madrid on a daily basis.

  • Which is the best airline for flights from Panama City to Madrid, Turkish Airlines or Air Europa?

    The two airlines most popular with KAYAK users for flights from Panama City to Madrid are Turkish Airlines and Air Europa. With an average price for the route of $787 and an overall rating of 7.3, Turkish Airlines is the most popular choice. Air Europa is also a great choice for the route, with an average price of $792 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Panama City to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Panama City with another airline. Booking your flights between Panama City and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $624 or less one-way and $824 or less round-trip.

Prefer to fly direct from Panama City to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Madrid Barajas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Tuesday

Air Europa, China Eastern, Copa Airlines, +6 more

Air Europa, China Eastern, +7 more

Wednesday

Air Europa, China Eastern, Copa Airlines, +6 more

Air Europa, China Eastern, +7 more

Thursday

Air Europa, China Eastern, Copa Airlines, +6 more

Air Europa, China Eastern, +7 more

Friday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Saturday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Sunday

Air Europa, China Eastern, Copa Airlines, +2 more

Air Europa, China Eastern, +3 more

See more direct flights

Direct returns

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Tuesday

Air Europa, China Eastern, Copa Airlines, +3 more

Air Europa, China Eastern, +4 more

Wednesday

Air Europa, China Eastern, Copa Airlines, +6 more

Air Europa, China Eastern, +7 more

Thursday

Air Europa, China Eastern, Copa Airlines, +6 more

Air Europa, China Eastern, +7 more

Friday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Saturday

Air Europa, British Airways, China Eastern, +6 more

Air Europa, British Airways, +7 more

Sunday

Air Europa, China Eastern, Copa Airlines, +2 more

Air Europa, China Eastern, +3 more

See more direct flights

Reviews of the top 5 airlines serving from Panama City to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
KLMOverall score based on 1381 reviews
7.1Entertainment
8.4Crew
7.7Comfort
7.8Boarding
7.3Food
Airline reviews

The baggage drop-off in Stuttgart is bad: after online check-in you cannot use the automated baggage drop off as indicated on the website. You can use the terminals but have to cue to 1 of three open and slowly working counters to drop the bags. took about 45 minutes wait time.

6.0 GoodSimon, Jul 2025STR - AMS
Read more KLM reviews

The baggage drop-off in Stuttgart is bad: after online check-in you cannot use the automated baggage drop off as indicated on the website. You can use the terminals but have to cue to 1 of three open and slowly working counters to drop the bags. took about 45 minutes wait time.

Our first flight was delayed so we missed our connecting flight. However it was easy to book a later flight on their app.

My flight was delayed by 6 hours then I missed BOTH of my connecting flights, I then had to stay in the AIRPORT at JFK because soooooo many people also suffered from missing flights and there was no hotels available. I would like to be compensated for this experience! I had to stay in the airport for over 16 hours!

Klm start boarding while somw air issue in the plan

Cabin crew were excellent, very proffesional, polite and friendly, in flight snack was underwhelming, a packet of cheese biscuits, im sure KLM could run to a sandwich!

You should not have to pay for WiFi in business class

This fight left ahead of time which meant it arrived early which was great. Staff were very professional, but as with all these Short hop Flights the food was a disappointing snack There was no entertainment on this flight, but I did not expect any

I flew premium economy and this was a good option. Although the seats didn’t recline much, I was able to get some sleep with my head propped against the window. The food was good and the entertainment was wonderful The staff were very attentive and professional

Overall very poor. Flight was disorganised, staff were rude and this is my second experience with KLM that I've had baggage go missing. It feels like, if you are an economy customer, KLM staff do not show you any care. I shall never fly with KLM again. Worst airline in Europe

Great boarding, great short flight but no entertainment whatsoever and no wifi. Prepare to disembark by a staircase.

I don't understand the concept of paying to get your personal luggage onboard and then asked to check it in.... either sell the space or don't, its a hassle to carry those all through the airport just to make a check in at the last minute.

The food was great and the service and attitude was amazing!!

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

It was an OK flight with below mediocre service by their flight attendants

Wasted a lot of time trying to find the CDG lounge - it was not next to the connecting flight gate like the Air France staff said.

My experience was good overall, the quality of the food really decreased! There used to be a choice between meat and fish now it’s between chicken and pasta! In the choices of entertainment meditation has been added which is very good. Soft chair workout to improve blood circulation and avoid phlebitis should be added.

The only reason the overall rating wasn't "excellent" was due to problems in claiming luggage. The bags are delivered to the main area (Cinta 35) for domestic passengers, but to a DIFFERENT ROOM for international arrivees. After waiting 30 minutes, someone (who didn't appear to be from Air France or the airport) told us to go to another area. There we found our bags, which appeared to have been awaiting us for a while. We had to go through a bag check before leaving the airport. If we had been alerted to this possibility, or better yet, been to go directly to Cinta 34, we could have eliminated quite a bit of waiting.

Much better than the major US Carriers especially in Biz Class.

I wish that the meal included a vegetable or even a salad instead of couscous! Why serve chicken with rice AND couscous? Service was good overall though a bit lacking in friendliness. Usually on air france I've been offered a glass of champagne before dinner, wine with dinner, and a digestif after dinner. We were only offered wine this time!

12 hours flight. Only one meal, not enough food. At the galley only water during the flight. Lavatories not clean. Headsets at extra cost.

Need to pay for a cup of water. No food. Need to pay for headsets.

Everything should improve! Service like a low cost but prices like a premium airline. Crew in general with bad manners arguing for everything. You pay for priority access but then they use buses, so your loose your advantage to put your carry on first. That was the purpose for paying for priority. Bording is a nightmare, people accessing the plane for bothering doors, front and rear, no matter which line do you have.

Issues with plane led to multiple gate changes and chaos. Very little communication from the ground crew led to cranky passengers.

I flew business class, at breakfast I asked for a small bottle of olive oil instead of butter and the flight attendant responded with a negative gesture.

They didn't even give us water, everything was sold

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

They gave me an upgrade but charged me for my bag. I felt abused because this had never happened to me before with an upgrade with another airline.

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

All flights with Air Europa you arrive late to the connections of other flights, I missed my train, I had to pay for my train again, the crew are antisocial, you are paying for a service, it is not free, thanks to the travelers they are there, it is the last time I fly with them,

Crew was excellent, great customer service, checked luggage took 1 hour and a half to come out at the baggage claim, the only negative thing about the flight.

Horrible experience airline crew was unprofessional. Flight was delayed. Suit cases did not arrive. Never flying iberia again

Iberia lost my bag, said they found it in another country, said they sent it to me, but never did. Went my whole trip without my stuff, but expecting it to show up because that’s what they said would happen. Their communication sucks, their website sucks, and to top it all off, their seats are small and uncomfortable. They’re bad at their jobs and they should feel bad about themselves. Do not even get me started on the flight home. AVOID!

The flight was delayed over 4 hours. Business class is just slightly upgraded economy.

Delayed and missed connections on leaving the states and returning Planes were old and small- very uncomfortable. Meals were good but very infrequent service for even water/drinks. No explanations for 3+ hour delay

Boarding on the buses isn’t efficient. Overall, it was great.

BEWARE!!! Iberia changes your seats at random. I paid for a window seat and they changed it to one in the middle aisle resting against the bathroom- can’t lean back + hear every flush. This on a 11 hour flight.. There were families that were broken up with separate seats all over the plane. Lots of upset passengers showing their seat confirmation to the besieged and helpless airline steward. Also, the gluten free meal was tasteless.

Iberia airlines was late on every flight I had. It was very difficult to communicate in English with iberia airlines and airport employees.

ground crew and check-in was pathetic - insisted on charging me for luggage even though the ticket said it was already included. They also accidentally sent my luggage through without a luggage tag and had to retrieve it. Generally, it was like a bad movie.

The app on phone and the online check in is not good, it would not give me the option of Spain or Madrid City in the drop down menu and I couldn't move forward with online check in.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

please see previous response; it covers the whole travel trajectory.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

The connection time is too short to pass through customs and once you do clear customs the connecting flight is in another terminal that is not close.

They charged me $120 to check one bag and then charged me another $120 for a carryon. Ridiculous!

Worst airline , charge for everything even for water, seat space is very bad

Everything you need to know for your flight from Panama City to Madrid

Information on your arrival and departure airports

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