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MFE - DSM

$273 Find Cheap Flights from McAllen to Des Moines - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$421
Typical prices: $299-$450
American Airlines
Sun 10/21Thu 10/25
MFE - DSM • 1 stop
Cheapest one-way
$273
Typical prices: $242-$310
United Airlines
Mon 1/1
MFE - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between McAllen and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 29% price drop
September
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $379 (round-trip)
Houston George Bush Intcntl (IAH)
Shortest trip • 4h 47m (one-way)
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Insights
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We hope you love your trip to Des Moines!

Cheap Flights from McAllen to Des Moines (MFE-DSM)

 

Cheap flights from McAllen to Des Moines with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Wed, Oct 21 - Sun, Oct 25
American Airlines Logo
4:37 pm - 11:07 pmMFE  McAllen Miller Intl-DSM Des Moines
6h 30m1 stop Dallas/Fort Worth
American Airlines Logo
7:42 pm - 12:02 amDSM  Des Moines-MFE McAllen Miller Intl
4h 20m1 stop Dallas/Fort Worth
$421American Airlines
Wed, Oct 21 - Sun, Oct 25
American Airlines Logo
5:05 am - 1:30 pmMFE  McAllen Miller Intl-DSM Des Moines
8h 25m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
7:42 pm - 12:02 amDSM  Des Moines-MFE McAllen Miller Intl
4h 20m1 stop Dallas/Fort Worth
$446American Airlines
Wed, Oct 21 - Sun, Oct 25
Delta Logo
5:20 am - 2:09 pmMFE  McAllen Miller Intl-DSM Des Moines
8h 49m2 stops Austin Bergstrom Atlanta Hartsfield-Jackson
Delta Logo
5:35 am - 3:22 pmDSM  Des Moines-MFE McAllen Miller Intl
9h 47m2 stops Atlanta Hartsfield-Jackson Austin Bergstrom
$652Delta

Price, demand and travel trends for McAllen to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from McAllen to Des Moines?

Round-trip flights from McAllen to Des Moines typically range from $299 to $450. The lowest price found in the past 5 days was $421, on American Airlines.

What's the cheapest day of the week to fly from McAllen to Des Moines?

Based on deals KAYAK users found in the last 12 months, Saturday is the cheapest day of the week to fly from McAllen to Des Moines. It’s 20% cheaper than the average day, while Friday is the most expensive, with prices 20% higher.

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Key details for McAllen to Des Moines flights

Low season

March

Cheapest flight

$273
Beat the crowds with an average 23% drop in travelers.
One-way flight from McAllen to Des Moines

When to book flights from McAllen to Des Moines

Are your dates flexible? Find out the best times to travel from McAllen to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your McAllen to Des Moines flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from McAllen to Des Moines?

    Only Economy Class is available on flights from McAllen to Des Moines.

  • How long is a flight from McAllen to Des Moines?

    A nonstop flight from McAllen to Des Moines takes 00m, covering 1,092 miles.

  • Do I need a passport to fly from McAllen to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a McAllen to Des Moines flight?

    Round-trip flights from McAllen to Des Moines range from $299 to $450, with an average of $390 over the past 12 months. Anything below $299 counts as a good deal.

  • Have flight prices from McAllen to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $421 to $652. That means the highest observed fare was about 54% higher than the lowest one.

  • How are flight prices from McAllen to Des Moines looking right now?

    One-way fares from McAllen to Des Moines are currently higher than usual. Average one-way flight prices are about $414, which is 51% above the typical average for this route.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $32 for economy cars. Top options include:

    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from McAllen to Des Moines?

    Flights from McAllen to Des Moines usually depart from McAllen Miller Intl (MFE) and arrive at Des Moines (DSM).

  • Which airports do connecting flights from McAllen to Des Moines pass through?

    Connecting flights from McAllen to Des Moines most commonly pass through:

    • Dallas/Fort Worth (DFW) - 88% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 12% of one-stop connections

  • Can I save money by using flexible dates for flights from McAllen to Des Moines?

    Yes. Flexible dates can save you up to 34% on flights from McAllen to Des Moines. Saturday is the cheapest departure day at $314 round-trip on average, while Friday is the most expensive at $471, a difference of $157.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from McAllen to Des Moines?

    Flying via Houston George Bush Intcntl (IAH) gives the shortest average 1-stop total travel time at 4h 47m, compared with 5h 18m via Dallas/Fort Worth (DFW).

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.

Your guide to booking McAllen to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Saturday departure and avoid flying on Friday. On this route, Saturday flights average $314, about $157 less than Friday fares (33% savings) based on the last 12 months.
  • If you can choose when to travel, plan your McAllen to Des Moines trip for January. Fares historically average $279 round-trip in that month - typically $281 less than the most expensive month, which is March (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.

    • Days Inn & Suites by Wyndham Des Moines Airport
    • Holiday Inn Des Moines-Airport/Conf Center By IHG
    • Homewood Suites by Hilton - Des Moines Airport

More options for your flight from McAllen to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines