MDE - GYE

$187 Find Cheap Flights from Medellín to Guayaquil - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Guayaquil departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$333
Typical prices: $302-$360
Avianca
Fri 9/4Fri 9/11
MDE - GYE • Non-stop
Cheapest one-way
$187
Typical prices: $174-$237
Avianca
Fri 9/4
MDE - GYE • Non-stop
Nonstop flights
Mon, Wed, Fri
You can fly direct with Avianca. Average duration is 2h 00m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top airlines
Cheapest • from $333 (round-trip)
Best reviews • 6.5 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Top layover airports
Cheapest • Avg $335 (round-trip)
Shortest trip • 4h 40m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
Most punctual • 93% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to travel
Cheapest • 13% price drop
Most popular
Good to know
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We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to Guayaquil (MDE-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Guayaquil

Fri, Sep 4 - Fri, Sep 11
Avianca Logo
4:50 pm - 6:50 pm
MDE
-
GYE
2h 00mnonstop
Avianca Logo
1:40 pm - 3:30 pm
GYE
-
MDE
1h 50mnonstop
$333Avianca
Wed, Nov 11 - Tue, Nov 17
Copa Airlines Logo
6:25 am - 5:35 pm
MDE
-
GYE
11h 10m
1 stop
Copa Airlines Logo
8:27 am - 2:15 pm
GYE
-
MDE
5h 48m
1 stop
$336Copa Airlines
Thu, Sep 3 - Wed, Sep 9
Avianca Logo
6:55 pm - 11:30 pm
MDE
-
GYE
4h 35m
1 stop
Avianca Logo
2:05 pm - 3:55 pm
GYE
-
MDE
1h 50mnonstop
$338Avianca
Thu, Sep 3 - Wed, Sep 9
Avianca Logo
6:55 pm - 11:30 pm
MDE
-
GYE
4h 35m
1 stop
Avianca Logo
2:05 pm - 3:55 pm
GYE
-
MDE
1h 50mnonstop
$339Avianca
Fri, Sep 4 - Fri, Sep 11
Avianca Logo
9:30 am - 2:35 pm
MDE
-
GYE
5h 05m
1 stop
Avianca Logo
3:45 pm - 8:20 pm
GYE
-
MDE
4h 35m
1 stop
$345Avianca
Fri, Sep 4 - Fri, Sep 11
Avianca Logo
9:30 am - 2:35 pm
MDE
-
GYE
5h 05m
1 stop
Avianca Logo
3:45 pm - 8:20 pm
GYE
-
MDE
4h 35m
1 stop
$346Avianca
Mon, Aug 3 - Sun, Aug 9
Copa Airlines Logo
6:20 pm - 11:38 pm
MDE
-
GYE
5h 18m
1 stop
Copa Airlines Logo
6:28 pm - 8:15 am
GYE
-
MDE
13h 47m
1 stop
$348Copa Airlines
Fri, Aug 28 - Fri, Aug 28
Avianca Logo
8:35 am - 3:55 pm
MDE
-
GYE
7h 20m
2 stops
Avianca Logo
6:50 pm - 11:35 pm
GYE
-
MDE
4h 45m
1 stop
$350Avianca
Thu, Jul 23 - Thu, Aug 6
Copa Airlines Logo
9:15 am - 5:31 pm
MDE
-
GYE
8h 16m
1 stop
Copa Airlines Logo
6:28 pm - 8:15 am
GYE
-
MDE
13h 47m
1 stop
$354Copa Airlines
Thu, Jul 23 - Thu, Aug 6
Copa Airlines Logo
4:30 pm - 11:38 pm
MDE
-
GYE
7h 08m
1 stop
Copa Airlines Logo
6:00 am - 10:55 am
GYE
-
MDE
4h 55m
1 stop
$355Copa Airlines
Booking Insights

KAYAK's insights & trends for Medellín to Guayaquil flights

Get data-powered insights and trends into flights from Medellín to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil departing in September.

What’s the cheapest day of the week to fly from Medellín to Guayaquil?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to Guayaquil, you should consider leaving on a Monday and avoid Wednesdays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Sundays and the most expensive ones on Tuesdays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil is February, where tickets cost $294 (return) on average. On the other hand, the most expensive months are May and April, where the average cost of round-trip tickets is $405 and $386 respectively.

Can I save money by flying with a layover from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $331 on average.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$187
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Medellín to Guayaquil

When to book flights from Medellín to Guayaquil

Are your dates flexible? Find out the best times to travel from Medellín to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Guayaquil flights

  • How many flights are there between Medellín Jose Maria Cordova Intl Airport and Guayaquil per day?

    There is a maximum of 1 nonstop flight a day that takes off from Medellín Jose Maria Cordova Intl Airport and lands in Guayaquil, with an average flight time of 2h 00m. The most common departure time is 4:00 pm and most flights take off in the afternoon. Each week, there are 3 flights.

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    In the last 5 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil was $187 for a one-way ticket and $333 for a round-trip.

  • Do I need a passport to fly between Medellín and Guayaquil?

    Yes

  • Which airports will I be using when flying from Medellín to Guayaquil?

    Medellín and Guayaquil are both served by 1 main airport. You will leave Medellín from Medellín Jose Maria Cordova Intl and will be arriving at Guayaquil Jose Joaquin de Olmedo.

  • Which aircraft models fly most regularly from Medellín to Guayaquil?

    The Airbus A320neo is the aircraft model that flies most regularly on the Medellín to Guayaquil flight route.

  • Which airline alliances offer flights from Medellín to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Medellín and Guayaquil.

  • On which days can I fly direct from Medellín to Guayaquil?

    You can catch a nonstop flight from Medellín to Guayaquil on Monday, Wednesday, and Friday.

  • How does KAYAK find such low prices on flights from Medellín to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Medellín with another airline. Booking your flights between Medellín and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Medellín to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Medellín Jose Maria Cordova Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Reviews of the top airline flying from Medellín to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.5
AviancaOverall score based on 2519 reviews
6.1Comfort
4.9Food
6.9Boarding
7.2Crew
5.3Entertainment
Airline reviews

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

8.0 ExcellentFelipe, Jan 2026
MDE - BGA
Read more Avianca reviews

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We waited for one hour to deboard the plane after landing. That could be better

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

Worst airline , charge for everything even for water, seat space is very bad

Almost we lost our connection from Bogota to Aruba 🥴 Because we get out late from the plane of Medellin

Avianca flights to Galapagos and back and well organized and on time.

Everything you need to know for your flight from Medellín to Guayaquil

Information on your arrival and departure airports