MDE - GYE

$159 Find Cheap Flights from Medellín to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Guayaquil departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Guayaquil, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$282
Overall average: $262
Avianca
Wed 5/20Mon 5/25
MDE - GYE • Non-stop
Cheapest one-way
$159
Typical prices: $149-$182
Avianca
Wed 5/20
MDE - GYE • Non-stop
Nonstop flights
3 days a week
Mon, Wed, Fri
You can fly direct with Avianca. Average duration is 2h 00m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Avianca
Cheapest • from $282 (round-trip)
Avianca
Best reviews • 6.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Bogotá (BOG)
Cheapest • Avg $330 (round-trip)
Panama City (PTY)
Shortest trip • 4h 38m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
Avianca
Most punctual • 92% on-time
Evening flights
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 5% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
June
Cheapest • 11% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
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Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to Guayaquil (MDE-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Guayaquil

Wed, May 20 - Mon, May 25
Avianca Logo
4:50 pm - 6:50 pm
MDE
-
GYE
2h 00mnonstop
Avianca Logo
1:40 pm - 3:30 pm
GYE
-
MDE
1h 50mnonstop
$282Avianca
Wed, May 20 - Mon, May 25
Avianca Logo
11:55 am - 5:35 pm
MDE
-
GYE
5h 40m
1 stop
Avianca Logo
1:40 pm - 3:30 pm
GYE
-
MDE
1h 50mnonstop
$287Avianca
Thu, Apr 30 - Mon, May 4
Copa Airlines Logo
12:40 pm - 5:31 pm
MDE
-
GYE
4h 51m
1 stop
Copa Airlines Logo
8:28 am - 2:45 pm
GYE
-
MDE
6h 17m
1 stop
$292Copa Airlines
Tue, May 12 - Wed, May 13
Copa Airlines Logo
10:35 am - 12:01 am
MDE
-
GYE
13h 26m
1 stop
Copa Airlines Logo
4:29 am - 9:40 am
GYE
-
MDE
5h 11m
1 stop
$293Copa Airlines
Wed, Apr 15 - Wed, Apr 22
Avianca Logo
10:15 am - 2:35 pm
MDE
-
GYE
4h 20m
1 stop
Avianca Logo
2:05 pm - 3:55 pm
GYE
-
MDE
1h 50mnonstop
$294Avianca
Tue, Mar 31 - Tue, Apr 7
Avianca Logo
6:55 pm - 11:30 pm
MDE
-
GYE
4h 35m
1 stop
Avianca Logo
9:10 am - 1:30 pm
GYE
-
MDE
4h 20m
1 stop
$300Avianca
Fri, Apr 17 - Fri, Jul 17
Copa Airlines Logo
9:15 am - 5:31 pm
MDE
-
GYE
8h 16m
1 stop
Copa Airlines Logo
6:27 pm - 8:15 am
GYE
-
MDE
13h 48m
1 stop
$322Copa Airlines
Fri, Apr 17 - Fri, Apr 24
Avianca Logo
4:50 pm - 6:50 pm
MDE
-
GYE
2h 00mnonstop
Avianca Logo
1:40 pm - 3:30 pm
GYE
-
MDE
1h 50mnonstop
$327Avianca
Wed, Mar 25 - Thu, May 7
Copa Airlines Logo
10:46 am - 5:33 pm
MDE
-
GYE
6h 47m
1 stop
Copa Airlines Logo
6:28 pm - 8:15 am
GYE
-
MDE
13h 47m
1 stop
$330Copa Airlines
Fri, Apr 17 - Fri, Apr 24
Avianca Logo
1:15 pm - 5:35 pm
MDE
-
GYE
4h 20m
1 stop
Avianca Logo
1:40 pm - 3:30 pm
GYE
-
MDE
1h 50mnonstop
$332Avianca
Booking Insights

KAYAK's insights & trends for Medellín to Guayaquil flights

Get data-powered insights and trends into flights from Medellín to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to Guayaquil?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to Guayaquil, you should consider leaving on a Monday and avoid Fridays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Wednesdays and the most expensive ones on Fridays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil is June, where tickets cost $261 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $326 and $324 respectively.

Can I save money by flying with a layover from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $116 on average.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil, you should book around 3 weeks before departure, which saves you about 5% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Find deals

Good to know

Low seasonNovember
Cheapest flight$159
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly with an average 9% increase in price.
Flight from Medellín to Guayaquil

When to book flights from Medellín to Guayaquil

Are your dates flexible? Find out the best times to travel from Medellín to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Guayaquil flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil was $159 for a one-way ticket and $282 for a round-trip.

  • Do I need a passport to fly between Medellín and Guayaquil?

    Yes

  • Which airports will I be using when flying from Medellín to Guayaquil?

    Medellín and Guayaquil are both served by 1 main airport. You will leave Medellín from Medellín Jose Maria Cordova Intl and will be arriving at Guayaquil Jose Joaquin de Olmedo.

  • Which aircraft models fly most regularly from Medellín to Guayaquil?

    The Airbus A320neo is the aircraft model that flies most regularly on the Medellín to Guayaquil flight route.

  • Which airline alliances offer flights from Medellín to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Medellín and Guayaquil.

  • On which days can I fly direct from Medellín to Guayaquil?

    You can catch a nonstop flight from Medellín to Guayaquil on Monday, Wednesday, and Friday.

  • How does KAYAK find such low prices on flights from Medellín to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Medellín with another airline. Booking your flights between Medellín and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil

  • Looking for a cheap flight? 25% of our users found flights on this route for $186 or less one-way.

Prefer to fly direct from Medellín to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Medellín Jose Maria Cordova Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Reviews of the top airline flying from Medellín to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.5
AviancaOverall score based on 2494 reviews
7.2Crew
5.4Entertainment
6.2Comfort
5.0Food
6.9Boarding
Airline reviews

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

2.0 MediocreAnonymous, Feb 2026
BOG - JFK
Read more Avianca reviews

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

I upgraded to businesses class. Because of that the flight was comfortable.

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

We waited for one hour to deboard the plane after landing. That could be better

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Everything you need to know for your flight from Medellín to Guayaquil

Information on your arrival and departure airports

Medellín (MDE)
Guayaquil (GYE)