MDE - GYE

$175 Find Cheap Flights from Medellín to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Guayaquil departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Guayaquil, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Medellín to Guayaquil (MDE-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Guayaquil

Fri, Nov 14 - Sun, Nov 30
Copa Airlines Logo
10:46 am - 11:41 pmMDE-GYE
12h 55m1 stop
Copa Airlines Logo
6:37 pm - 8:18 amGYE-MDE
13h 41m1 stop
$297Copa Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
Copa Airlines Logo
10:46 am - 11:41 pmMDE-GYE
12h 55m1 stop
Copa Airlines Logo
6:37 pm - 8:18 amGYE-MDE
13h 41m1 stop
$305Copa Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
Copa Airlines Logo
9:17 am - 1:32 pmMDE-GYE
4h 15m1 stop
Copa Airlines Logo
8:30 am - 2:45 pmGYE-MDE
6h 15m1 stop
$306Copa Airlines
Find Deal
Thu, Nov 20 - Thu, Nov 27
Copa Airlines Logo
9:17 am - 1:36 pmMDE-GYE
4h 19m1 stop
Copa Airlines Logo
6:37 pm - 8:18 amGYE-MDE
13h 41m1 stop
$317Copa Airlines
Find Deal
Mon, Dec 1 - Mon, Dec 8
Avianca Logo
4:30 pm - 6:30 pmMDE-GYE
2h 00mnonstop
Avianca Logo
1:45 pm - 3:35 pmGYE-MDE
1h 50mnonstop
$321Avianca
Find Deal
Mon, Dec 1 - Sat, Dec 6
Avianca Logo
4:30 pm - 6:30 pmMDE-GYE
2h 00mnonstop
Avianca Logo
3:30 am - 7:45 amGYE-MDE
4h 15m1 stop
$327Avianca
Find Deal
Thu, Nov 20 - Thu, Nov 27
Multiple Airlines Logo
6:30 am - 4:53 pmMDE-GYE
10h 23m2 stops
Multiple Airlines Logo
9:05 am - 1:20 pmGYE-MDE
4h 15m1 stop
$363Multiple Airlines
Find Deal
Mon, Dec 1 - Mon, Dec 8
Multiple Airlines Logo
7:55 pm - 1:05 amMDE-GYE
5h 10m1 stop
Multiple Airlines Logo
7:13 pm - 11:50 amGYE-MDE
16h 37m2 stops
$392Multiple Airlines
Find Deal
Mon, Dec 1 - Sun, Dec 7
LATAM Airlines Logo
6:30 am - 3:38 pmMDE-GYE
9h 08m2 stops
LATAM Airlines Logo
1:35 pm - 11:30 pmGYE-MDE
9h 55m2 stops
$404LATAM Airlines
Find Deal
Thu, Nov 20 - Thu, Nov 27
LATAM Airlines Logo
7:20 am - 4:53 pmMDE-GYE
9h 33m2 stops
LATAM Airlines Logo
3:13 pm - 11:35 pmGYE-MDE
8h 22m2 stops
$422LATAM Airlines
Find Deal

Everything you should know

Top airlines
Copa Airlines
Cheapest • from $297 (round-trip)
Avianca
Best reviews • 6.7 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
January
Cheapest • 10% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
3 days a week
There are direct flights from Medellín to Guayaquil 3 days a week: Mon, Wed, Fri.
Direct flights
Direct flights
Direct flights
Direct flights
Cheapest round-trip
$297
Overall average: $269
Copa Airlines
Fri 11/14Sun 11/30
MDE - GYE • 1 stop
Cheapest non-stop
$321
Typical prices: $243-352
Avianca
Mon 12/1Mon 12/8
MDE - GYE • Non-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guayaquil!
Booking Insights

KAYAK's insights & trends for Medellín to Guayaquil flights

Get data-powered insights and trends into flights from Medellín to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to Guayaquil?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to Guayaquil, you should consider leaving on a Saturday and avoid Fridays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Saturdays and the most expensive ones on Fridays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil is January, where tickets cost $248 (return) on average. On the other hand, the most expensive months are September and August, where the average cost of round-trip tickets is $304 and $300 respectively.

Can I save money by flying with a layover from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $252, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil, you should book around 4 weeks before departure, which saves you about 16% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Find deals

Good to know

Low seasonOctober
Cheapest flight$175
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Medellín to Guayaquil

When to book flights from Medellín to Guayaquil

Are your dates flexible? Find out the best times to travel from Medellín to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Guayaquil flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Guayaquil was $175 for a one-way ticket and $297 for a round-trip.

  • Do I need a passport to fly between Medellín and Guayaquil?

    Yes

  • Which airports will I be using when flying from Medellín to Guayaquil?

    Medellín and Guayaquil are both served by 1 main airport. You will leave Medellín from Medellín Jose Maria Cordova Intl and will be arriving at Guayaquil Jose Joaquin de Olmedo.

  • Which aircraft models fly most regularly from Medellín to Guayaquil?

    The Airbus A320neo is the aircraft model that flies most regularly on the Medellín to Guayaquil flight route.

  • Which airline alliances offer flights from Medellín to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Medellín and Guayaquil.

  • On which days can I fly direct from Medellín to Guayaquil?

    You can catch a nonstop flight from Medellín to Guayaquil on Monday, Wednesday, and Friday.

  • How does KAYAK find such low prices on flights from Medellín to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Medellín with another airline. Booking your flights between Medellín and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Medellín to Guayaquil?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo.
Find which airlines fly direct from Medellín Jose Maria Cordova Intl Airport to Guayaquil Jose Joaquin de Olmedo Airport, which days they fly and book direct flights.

Direct departures

Medellín Jose Maria Cordova Intl to Guayaquil Jose Joaquin de Olmedo

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Direct returns

Guayaquil Jose Joaquin de Olmedo to Medellín Jose Maria Cordova Intl

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

See more direct flights

Reviews of the top airline flying from Medellín to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.7
AviancaOverall score based on 2447 reviews
5.1Food
7.3Crew
6.3Comfort
5.5Entertainment
7.0Boarding
Airline reviews

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

6.0 GoodJuan, Sep 2025CTG - BOG
Read more Avianca reviews

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Everything you need to know for your flight from Medellín to Guayaquil

Information on your arrival and departure airports

Medellín (MDE)
Guayaquil (GYE)

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