MDE - STI

$313 Find Cheap Flights from Medellín to Santiago de los Caballeros - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$459
Typical prices: $405-$668
Copa Airlines
Wed 11/28Wed 12/5
MDE - STI • 1 stop
Cheapest one-way
$313
Typical prices: $283-$329
Copa Airlines
Tue 2/13
MDE - STI • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Medellín Jose Maria Cordova Intl Airport and Santiago de los Caballeros. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
August
Cheapest • 30% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Panama City Tocumen Intl (PTY)
Cheapest • Avg $479 (round-trip)
Miami (MIA)
Shortest trip • 9h 17m (one-way)
Insights
Insights
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We hope you love your trip to Santiago de los Caballeros!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to Santiago de los Caballeros (MDE-STI)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Santiago de los Caballeros

Sat, Nov 28 - Sat, Dec 5
Copa Airlines Logo
8:35 am - 2:54 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
5h 19m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:00 pm - 2:15 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
23h 15m1 stop Panama City Tocumen Intl
$459Copa Airlines
Thu, Jan 21 - Sat, Mar 6
Copa Airlines Logo
9:15 am - 2:53 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
4h 38m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:46 pm - 8:00 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
5h 14m1 stop Panama City Tocumen Intl
$523Copa Airlines
Fri, Nov 20 - Mon, Nov 23
Copa Airlines Logo
6:25 pm - 2:54 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
19h 29m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:01 pm - 2:45 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
23h 44m1 stop Panama City Tocumen Intl
$564Copa Airlines
Mon, Feb 1 - Sat, Feb 6
Copa Airlines Logo
8:35 am - 2:53 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
5h 18m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:56 pm - 8:15 amSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
17h 19m1 stop Panama City Tocumen Intl
$592Copa Airlines
Wed, Dec 23 - Mon, Dec 28
Copa Airlines Logo
6:20 pm - 2:58 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
19h 38m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:00 pm - 8:35 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
5h 35m1 stop Panama City Tocumen Intl
$609Copa Airlines
Sat, Dec 26 - Sat, Jan 9
Copa Airlines Logo
6:25 am - 2:58 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
7h 33m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:54 pm - 8:15 amSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
17h 21m1 stop Panama City Tocumen Intl
$639Copa Airlines
Sat, Dec 26 - Sat, Jan 9
Copa Airlines Logo
6:25 am - 2:58 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
7h 33m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:54 pm - 8:15 amSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
17h 21m1 stop Panama City Tocumen Intl
$663Copa Airlines
Sun, Dec 20 - Mon, Dec 28
Copa Airlines Logo
6:20 pm - 2:58 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
19h 38m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:00 pm - 2:45 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
23h 45m1 stop Panama City Tocumen Intl
$690Copa Airlines
Mon, Nov 9 - Thu, Nov 12
Copa Airlines Logo
8:35 am - 2:54 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
5h 19m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:01 pm - 8:15 amSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
17h 14m1 stop Panama City Tocumen Intl
$695Copa Airlines
Fri, Nov 13 - Mon, Nov 16
Copa Airlines Logo
3:15 pm - 2:54 pmMDE  Medellín Jose Maria Cordova Intl-STI Santiago de los Caballeros
22h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:01 pm - 2:45 pmSTI  Santiago de los Caballeros-MDE Medellín Jose Maria Cordova Intl
23h 44m1 stop Panama City Tocumen Intl
$726Copa Airlines
Booking Insights

Price, demand and travel trends for Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

Round-trip flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros typically range from $405 to $668. The lowest price found in the past 5 days was $459, on Copa Airlines.

What’s the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

•August is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros at $345 round-trip.
•November ($1,393) and May ($825) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 303% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros flights

Low season

November

Cheapest flight

$313
Beat the crowds with an average 52% drop in travelers.
The most popular month to fly with an average 52% increase in travelers.
One-way flight from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros

When to book flights from Medellín to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from Medellín to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    Only Economy Class is available on flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros.

  • How long is a flight from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    A nonstop flight from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros takes 00m, covering 970 miles.

  • Do I need a passport to fly from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros flight?

    Round-trip flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros range from $405 to $668, with an average of $491 over the past 12 months. Anything below $405 counts as a good deal.

  • How are flight prices from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros looking right now?

    One-way fares from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros are currently higher than usual. Average one-way flight prices are about $572, which is 94% above the typical average for this route.

  • What car rental options are available at Santiago de los Caballeros Airport (STI)?

    Santiago de los Caballeros Airport (STI) hosts 5 major car rental companies, with daily rates averaging $33 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • Alamo
    • Infinity Car Rental
    • Europcar

  • Which airports can I use when flying from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    Flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros usually depart from Medellín Jose Maria Cordova Intl (MDE) and arrive at Santiago de los Caballeros (STI).

  • Which airports do connecting flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros pass through?

    One-stop flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 83% of one-stop connections
    • Fort Lauderdale (FLL) - 10% of one-stop connections
    • Miami (MIA) - 7% of one-stop connections

  • Can I save money by using flexible dates for flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    Yes. Flexible dates can save you up to 74% on flights from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros. Thursday is the cheapest departure day at $441 round-trip on average, while Sunday is the most expensive at $1,634, a difference of $1,193.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 6h 24m, compared with 9h 17m via Miami (MIA) and 19h 45m via Fort Lauderdale (FLL).

  • What is the time difference between Medellín Jose Maria Cordova Intl Airport and Santiago de los Caballeros?

    Santiago de los Caballeros is 1 hour ahead of Medellín Jose Maria Cordova Intl Airport (Atlantic Time vs Colombia Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Sunday. On this route, Thursday flights average $441, about $1,193 less than Sunday fares (73% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Medellín Jose Maria Cordova Intl Airport to Santiago de los Caballeros trip for August. Fares historically average $345 round-trip in that month - typically $1,048 less than the most expensive month, which is November (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago de los Caballeros Airport.

    • Hodelpa Garden Court

More options for your flight from Medellín to Santiago de los Caballeros

Complete your trip to Santiago de los Caballeros with a hotel stay or car rental

Car rentals in Santiago de los Caballeros
Hotels in Santiago de los Caballeros