MDE - SAN

$310 Find Cheap Flights from Medellín to San Diego - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to San Diego departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$416
Typical prices: $497-$638
Multiple Airlines
Mon 8/17Wed 10/21
MDE - SAN • 2 stops
Cheapest one-way
$310
Typical prices: $315-$440
Multiple Airlines
Tue 10/20
MDE - SAN • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Medellín and San Diego. You'll need at least 1 connection.
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Top layover airports
Cheapest • Avg $585 (round-trip)
Shortest trip • 10h 07m (one-way)
Insights
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When to travel
Cheapest • 34% price drop
Most popular
Good to know
Good to know
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to San Diego (MDE-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to San Diego

Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
2:10 pm - 6:09 pm
MDE
-
SAN
29h 59m
2 stops
Multiple Airlines Logo
11:53 am - 1:10 pm
SAN
-
MDE
23h 17m
2 stops
$416Multiple Airlines
Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
2:10 pm - 6:09 pm
MDE
-
SAN
29h 59m
2 stops
Multiple Airlines Logo
11:53 am - 1:10 pm
SAN
-
MDE
23h 17m
2 stops
$417Multiple Airlines
Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
2:10 pm - 6:09 pm
MDE
-
SAN
29h 59m
2 stops
Multiple Airlines Logo
11:53 am - 1:10 pm
SAN
-
MDE
23h 17m
2 stops
$419Multiple Airlines
Tue, Aug 4 - Fri, Aug 14
Multiple Airlines Logo
10:40 pm - 8:08 pm
MDE
-
SAN
23h 28m
1 stop
Multiple Airlines Logo
10:04 am - 1:10 pm
SAN
-
MDE
25h 06m
2 stops
$449Multiple Airlines
Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
10:40 pm - 8:08 pm
MDE
-
SAN
23h 28m
1 stop
Multiple Airlines Logo
4:00 pm - 1:10 pm
SAN
-
MDE
19h 10m
2 stops
$451Multiple Airlines
Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
10:40 pm - 8:08 pm
MDE
-
SAN
23h 28m
1 stop
Multiple Airlines Logo
4:00 pm - 1:10 pm
SAN
-
MDE
19h 10m
2 stops
$468Multiple Airlines
Mon, Aug 17 - Wed, Oct 21
Multiple Airlines Logo
2:10 pm - 6:09 pm
MDE
-
SAN
29h 59m
2 stops
Multiple Airlines Logo
11:53 am - 1:10 pm
SAN
-
MDE
23h 17m
2 stops
$471Multiple Airlines
Sat, Oct 10 - Thu, Oct 15
Multiple Airlines Logo
2:10 pm - 8:50 am
MDE
-
SAN
20h 40m
2 stops
Multiple Airlines Logo
7:48 pm - 1:10 pm
SAN
-
MDE
15h 22m
2 stops
$472Multiple Airlines
Mon, Jul 27 - Mon, Aug 17
Multiple Airlines Logo
2:10 pm - 3:05 pm
MDE
-
SAN
26h 55m
2 stops
Multiple Airlines Logo
10:04 am - 1:10 pm
SAN
-
MDE
25h 06m
2 stops
$474Multiple Airlines
Mon, Jul 27 - Mon, Aug 17
Multiple Airlines Logo
2:10 pm - 3:05 pm
MDE
-
SAN
26h 55m
2 stops
Multiple Airlines Logo
10:04 am - 1:10 pm
SAN
-
MDE
25h 06m
2 stops
$476Multiple Airlines
Booking Insights

KAYAK's insights & trends for Medellín to San Diego flights

Get data-powered insights and trends into flights from Medellín to San Diego to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to San Diego?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to San Diego departing in August.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to San Diego is March, where tickets cost $421 (return) on average. On the other hand, the most expensive months are January and June, where the average cost of round-trip tickets is $832 and $803 respectively.

Good to know

Low seasonFebruary
Cheapest flight$310
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Medellín to San Diego

When to book flights from Medellín to San Diego

Are your dates flexible? Find out the best times to travel from Medellín to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to San Diego flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to San Diego?

    In the last 5 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to San Diego was $310 for a one-way ticket and $416 for a round-trip.

  • Do I need a passport to fly between Medellín and San Diego?

    A passport is required to fly from Medellín to San Diego.

  • Which aircraft models fly most regularly from Medellín to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medellín to San Diego?

    Star Alliance is the only airline alliance operating flights between Medellín and San Diego.

  • Which is the best airline for flights from Medellín to San Diego, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to San Diego are Copa Airlines and United Airlines. With an average price for the route of $550 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $589 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medellín to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Medellín with another airline. Booking your flights between Medellín and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Medellín to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Medellín to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1568 reviews
7.8Boarding
7.4Comfort
6.8Entertainment
6.9Food
8.1Crew
Airline reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

4.0 OkayAnonymous, Jun 2026
PTY - AUS
Read more Copa Airlines reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

Good trip, excellent attention. I like Copa Airlines, the best. 👍🏻

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

other than a slight delay in takeoff from Panama , the flights were excellent ..... we will continue to use Copa whenever possible for flights to and from Central and South America ....

Monitor control didn’t work & couldn’t figure out how to lay bed flat so I slept very poorly. Cabin was very cold

Excellent flight. On time. Great staff. Clean and crisp cabin.

The airline was fine, but I did want to share about Kayak's error through Underpricer. The original booking was purchased with ANA, and Kayak booked it with United. This is a mistake that should not be happening, since the price I paid was with ANA and that was my preference. I appreciate the efforts done to make this right by paying for the seat preference, but sitting in the back of the airplane under economy is not enough to make this error right. ANA Airlines was the experience I wanted considering this was a life time experience that my family and I wanted to have as part of our Japanese experience. Please work on your affiliation with Underpricer to make the right bookings that the customer pays for. In my situation, I could of paid less for a United ticket versus my original payment with ANA Airlines.

The Manila airport was under renovation so there was no business class lounge. The double security check was disorganized and the flight attendants were grouchy.

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Was a pain having to leave the plane and reboard but glad the plane was fixed

Connecting flights were poor,especially in Naples.our Lufthansa air bus was a joke.way too small for that long of a flight.no room at all.couldn’t even get out of the seats to move around or go to the bathrooms.we thought we were getting an actual air bus,double decker.i will never fly that long in a plane like that again.kind of misleading to call it an air bus.we actually had more room on our buses that we used.

For a 22 minute flight all you expect is for it to be safe and comfortable

Lost connnection had to stayON in Chicago Was a mess

Booked economy through United - air canada treated it as standby and was almost refused boarding.

Everything you need to know for your flight from Medellín to San Diego

Information on your arrival and departure airports