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Cheap Flights from South America to San Diego

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to San Diego

Mon, Dec 7 - Fri, Jan 29
American Airlines Logo
11:55 pm - 10:18 amBOG  Bogotá El Dorado-SAN San Diego
13h 23m1 stop Dallas/Fort Worth
American Airlines Logo
6:15 am - 11:01 pmSAN  San Diego-BOG Bogotá El Dorado
13h 46m1 stop Dallas/Fort Worth
$499American Airlines
Wed, Sep 16 - Tue, Sep 22
American Airlines Logo
6:30 am - 10:25 pmBOG  Bogotá El Dorado-SAN San Diego
17h 55m1 stop Miami
American Airlines Logo
7:15 am - 10:30 pmSAN  San Diego-BOG Bogotá El Dorado
13h 15m1 stop Dallas/Fort Worth
$499American Airlines
Thu, Oct 22 - Sun, Oct 25
United Airlines Logo
9:45 am - 5:26 pmMDE  Medellín Jose Maria Cordova Intl-SAN San Diego
33h 41m2 stops Houston George Bush Intcntl Los Angeles Los Angeles
United Airlines Logo
5:00 pm - 9:15 pmSAN  San Diego-MDE Medellín Jose Maria Cordova Intl
26h 15m1 stop Houston George Bush Intcntl
$524United Airlines
Thu, Oct 22 - Sun, Oct 25
United Airlines Logo
9:45 am - 1:17 pmMDE  Medellín Jose Maria Cordova Intl-SAN San Diego
29h 32m1 stop Houston George Bush Intcntl
United Airlines Logo
5:00 pm - 9:15 pmSAN  San Diego-MDE Medellín Jose Maria Cordova Intl
26h 15m1 stop Houston George Bush Intcntl
$524United Airlines
Mon, Oct 5 - Fri, Oct 30
Copa Airlines Logo
9:15 am - 6:30 pmMDE  Medellín Jose Maria Cordova Intl-SAN San Diego
11h 15m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:30 pm - 2:45 pmSAN  San Diego-MDE Medellín Jose Maria Cordova Intl
14h 15m1 stop Panama City Tocumen Intl
$525Copa Airlines
Tue, Oct 20 - Thu, Oct 29
Copa Airlines Logo
4:30 pm - 6:30 pmMDE  Medellín Jose Maria Cordova Intl-SAN San Diego
28h 00m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:30 pm - 9:45 amSAN  San Diego-MDE Medellín Jose Maria Cordova Intl
9h 15m1 stop Panama City Tocumen Intl
$525Copa Airlines
Thu, Sep 24 - Thu, Oct 15
Multiple Airlines Logo
4:25 am - 5:10 pmBOG  Bogotá El Dorado-SAN San Diego
14h 45m2 stops San Salvador El Salvador Intl San Francisco
Multiple Airlines Logo
7:55 pm - 12:00 pmSAN  San Diego-BOG Bogotá El Dorado
14h 05m2 stops San Francisco San Salvador El Salvador Intl
$564Multiple Airlines
Wed, Sep 30 - Thu, Oct 29
GOL Logo
6:30 am - 9:48 pmBOG  Bogotá El Dorado-SAN San Diego
17h 18m2 stops Miami Dallas/Fort Worth
GOL Logo
6:20 am - 10:10 pmSAN  San Diego-BOG Bogotá El Dorado
13h 50m2 stops Philadelphia Miami
$571GOL
Tue, Sep 29 - Sat, Oct 3
Multiple Airlines Logo
9:05 am - 10:08 amBOG  Bogotá El Dorado-SAN San Diego
27h 03m2 stops San Salvador El Salvador Intl San Francisco
Multiple Airlines Logo
7:00 am - 4:15 amSAN  San Diego-BOG Bogotá El Dorado
19h 15m1 stop Montreal Pierre Elliott Trudeau Intl
$582Multiple Airlines
Wed, Oct 14 - Wed, Oct 28
GOL Logo
5:00 am - 10:43 pmVCP  Sao Paulo Viracopos-SAN San Diego
45h 43m2 stops Rio de Janeiro–Galeão Intl Miami
GOL Logo
12:56 pm - 10:55 pmSAN  San Diego-VCP Sao Paulo Viracopos
29h 59m2 stops Miami Rio de Janeiro–Galeão Intl
$875GOL
Useful Info

Good to know

Low season

February

Cheapest flight

$307
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Medellín to San Diego

FAQs for booking flights from South America to San Diego

  • How does KAYAK find such low prices on flights from South America to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to San Diego

 
Need help choosing which airline to fly with from South America to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8531 reviews
7.2Food
8.5Crew
7.8Comfort
7.8Entertainment
8.1Boarding
Airline reviews

Both of my flights to and from JFK experienced significant delays. Most notably, my first flight was delayed by six hours due to crew members being affected by delays on a previous flight. While I understand that disruptions can occur, Delta’s staffing and operational planning should include sufficient contingency measures to handle situations like this rather than placing the full burden of those delays on customers. Additionally, the $12 meal voucher offered as compensation was inadequate, particularly given the high cost of food and beverages at the airport. Considering the length of the delay and the substantial inconvenience caused, I believe more meaningful compensation would have been appropriate.

4.0 OkayXizhe, Aug 2026
Read more Delta reviews

Both of my flights to and from JFK experienced significant delays. Most notably, my first flight was delayed by six hours due to crew members being affected by delays on a previous flight. While I understand that disruptions can occur, Delta’s staffing and operational planning should include sufficient contingency measures to handle situations like this rather than placing the full burden of those delays on customers. Additionally, the $12 meal voucher offered as compensation was inadequate, particularly given the high cost of food and beverages at the airport. Considering the length of the delay and the substantial inconvenience caused, I believe more meaningful compensation would have been appropriate.

Crew was real good, flight was smooth and came in early.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

Everything was very good other than I had selected a specific seat when I booked the flight and they changed it once I checked-in the day before my flight. I was still in first class but lost my aisle seat for a window seat. Being tall, the aisle offers more comfort so I always select an aisle seat.

Flight diverted in SD. Later take off in Seattle by 1.3hrs

Was a great smooth flight from Detroit to San Diego.

The boarding process was terrible especially with an indirect flight Chicago to Seattle to San Diego was terrible talking about we overbooked a flight idk if I’d take this airline ever again we got off our flight from Chicago to Seattle and we traveled for business and they told us our connecting flight was over booked and their was no seats asking people to take a delayed next flight and they don’t tell anyone coughing to wear masks seats 30A-B were terrible during the flight no one wants to sit next to people coughing all around I don’t want to be sick traveling for work or get sick anytime it’s very upsetting the staff doesn’t take this stuff serious to tell them to wear masks when they see people coughing and sneezing

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

The plane left over an hour late. I missed my connection going to Tokyo. They haven’t sent my bag to Thailand, where I ended up. It took me over 32 hours to get here. Very bad experience so far. I hope they can fix this and get my bag to me, within 24 hours it doesn’t look good at this time.

This flight did not take place because the passenger was in the hospital. We have made so many attempts to rebook this flight and have spoken to so many United Airlines representatives and everyone is giving you a different answer. It has become beyond frustrating to the point where we now have to seek legal help. This is a family of 4 so a lot of money was spent to purchase 4 tickets to go visit their daughter/sister who is a US servicewoman in Okinawa and to be treated with such disdain and disrespect is beyond reprehensible. The main traveler was given sent a letter by United confirming a refund on the tickets and to be able to use them but every attempt to use this has been met with a negative response so much so that the client is over stressed.

Delayed 2 hours while stuck on the aircraft. If the luggage was properly loaded the first time we probably wouldn’t have been delayed at all

UA594 was delayed multiple times. I ended up getting picked up so I can make it in time for work 6AM on Monday, 7/6/2026

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Was a pain having to leave the plane and reboard but glad the plane was fixed

Connecting flights were poor,especially in Naples.our Lufthansa air bus was a joke.way too small for that long of a flight.no room at all.couldn’t even get out of the seats to move around or go to the bathrooms.we thought we were getting an actual air bus,double decker.i will never fly that long in a plane like that again.kind of misleading to call it an air bus.we actually had more room on our buses that we used.

For a 22 minute flight all you expect is for it to be safe and comfortable

Lost connnection had to stayON in Chicago Was a mess

Booked economy through United - air canada treated it as standby and was almost refused boarding.

Was given all 3 boarding passes. Was refused boarding to Brasilia in Miami even though I had up to date Brazilian Visa and US passport. Had to return to Phoenix as trip was cancelled. Waiting for refund of the fare. Missed my son's birthday and visit with him and his wife.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Lost luggage, people are not very nice to help you , I was just instructed to fill out a baggage claim online, they were not helpful when I had additional questions after I completed the form on my phone.

They are not ready for international flights, poor service and food, no screen info on the seat.

Gol has an interesting choice of words. When they say “priority access”, this means you’re boarding on the seventh or eighth group.

American rescheduled with GOL. An error was made that caused significant issues including nit being able to checkin not having assigned seats, not getting seats together, arriving late, and the crew made no attempt to help.

They are a mess. It appears they hired a third party to staff their check in desk and simply did not train them. I will avoid flying with them in the future. It took 50 minutes for them to check in 3 parties on front of us. On the way back. It took just under one hour for our luggage to show up...

Awful! We boarded and then sat on the plane for 50 mins before having to deplane due to a maintenance issue which should have been addressed before boarding. Then we had to change terminals as there was no other plane for us at the current terminal. Then we waited another 2 and a half hours to board again only to wait for 50 mins on the plane again for the snacks to be brought from the broken plane. And once we were on the flight we still only got the complimentary cookie and soda or water. No food vouchers provided even though we had waited over 3 hours for our flight.

The seat when "flat" was not flat and pad was too thin to cover it.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

We are too tired and frustrated to comment politely at this point

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The service and food needs to improve to catch up with other international flights

The flight crew was fantastic! Which the seats had a small TV.

also wi-fi never worked attendant said satellite coverage is spotty over water ..... but we were over land!

They attended to my needs as I couldn't walk and they provided a wheelchair for me.q

This time my flight was smooth and uneventful. They started boarding even earlier than it was scheduled. I was pleasantly surprised. Thank you!

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