$280 Find Cheap Flights from Medellín to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to South Carolina departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to South Carolina, as well as popular online travel agencies
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Cheap Flights from Medellín to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Myrtle Beach
Myrtle Beach2 stops$706
Charlotte
Charlotte2 stops$462
Myrtle Beach
Myrtle Beach2 stops$706
Charlotte
Charlotte2 stops$462

Book Cheap Medellín to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to South Carolina

Mon, Jun 1 - Fri, Jun 12
Multiple Airlines Logo
8:05 am - 11:40 pm
MDE
-
CLT
14h 35m
2 stops
Multiple Airlines Logo
9:07 pm - 6:52 pm
CLT
-
MDE
22h 45m
2 stops
$462Multiple Airlines
Wed, May 13 - Thu, May 14
Multiple Airlines Logo
5:00 am - 11:40 pm
MDE
-
CLT
17h 40m
2 stops
Multiple Airlines Logo
9:07 pm - 7:45 pm
CLT
-
MDE
23h 38m
2 stops
$469Multiple Airlines
Fri, May 29 - Sun, Jun 14
Multiple Airlines Logo
7:00 am - 11:40 pm
MDE
-
CLT
15h 40m
2 stops
Multiple Airlines Logo
9:07 pm - 11:30 pm
CLT
-
MDE
27h 23m
2 stops
$481Multiple Airlines
Wed, May 20 - Tue, May 26
Multiple Airlines Logo
1:00 pm - 11:40 pm
MDE
-
CLT
9h 40m
1 stop
Multiple Airlines Logo
7:30 am - 9:25 pm
CLT
-
MDE
14h 55m
1 stop
$482Multiple Airlines
Wed, May 13 - Thu, May 14
Multiple Airlines Logo
5:05 am - 12:12 pm
MDE
-
CLT
30h 07m
2 stops
Multiple Airlines Logo
6:33 pm - 7:40 pm
CLT
-
MDE
26h 07m
2 stops
$483Multiple Airlines
Tue, May 12 - Tue, May 26
Multiple Airlines Logo
9:05 pm - 11:40 pm
MDE
-
CLT
25h 35m
3 stops
Multiple Airlines Logo
7:30 am - 4:20 pm
CLT
-
MDE
9h 50m
2 stops
$484Multiple Airlines
Thu, May 28 - Mon, Jun 1
United Airlines Logo
9:45 am - 9:59 am
MDE
-
MYR
23h 14m
2 stops
United Airlines Logo
11:25 am - 9:10 pm
MYR
-
MDE
34h 45m
2 stops
$706United Airlines
Thu, Jun 4 - Sat, Jun 6
United Airlines Logo
9:45 am - 9:59 am
MDE
-
MYR
23h 14m
2 stops
United Airlines Logo
10:34 am - 9:10 pm
MYR
-
MDE
35h 36m
2 stops
$749United Airlines
Thu, Jun 4 - Sat, Jun 6
United Airlines Logo
9:45 am - 9:59 am
MDE
-
MYR
23h 14m
2 stops
United Airlines Logo
10:34 am - 9:10 pm
MYR
-
MDE
35h 36m
2 stops
$756United Airlines
Mon, May 25 - Fri, Jul 31
American Airlines Logo
11:59 pm - 3:58 pm
MDE
-
MYR
14h 59m
2 stops
American Airlines Logo
6:50 am - 11:48 pm
MYR
-
MDE
17h 58m
2 stops
$772American Airlines
Booking Insights

KAYAK's insights & trends for Medellín to South Carolina flights

Get data-powered insights and trends into flights from Medellín to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to South Carolina is April, when tickets cost $279 (return) on average. On the other hand, the most expensive months are February and January, when the average cost of round-trip tickets is $661 and $573 respectively.

Find deals

Good to know

Low seasonFebruary
Cheapest flight$280
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Medellín to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Medellín to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Medellín to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Medellín to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Medellín to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medellín to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Medellín to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11681 reviews
6.9Entertainment
7.9Crew
6.4Food
7.2Comfort
7.5Boarding
Airline reviews

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

10.0 ExcellentStan, Apr 2026
LAX - PHL
Read more American Airlines reviews

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

Poor... food was horrible, boarding very slow, service on board mediocre

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Everything you need to know for your flight from Medellín to South Carolina

Information on your arrival and departure airports

Medellín (MDE)