$194 Find Cheap Flights from Medellín to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to South Carolina departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to South Carolina, as well as popular online travel agencies
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Cheap Flights from Medellín to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Myrtle Beach
Myrtle Beach1 stop$534
Charlotte
Charlotte1 stop$309
Myrtle Beach
Myrtle Beach1 stop$534
Charlotte
Charlotte1 stop$309

Book Cheap Medellín to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to South Carolina

Thu, Jan 15 - Tue, Jan 20
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m1 stop
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
$309Spirit Airlines
Thu, Jan 22 - Sun, Jan 25
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m1 stop
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
$351Spirit Airlines
Sat, Jan 24 - Sat, Jan 31
Multiple Airlines Logo
1:00 pm - 12:40 am
MDE
-
CLT
11h 40m1 stop
Multiple Airlines Logo
6:00 am - 9:40 pm
CLT
-
MDE
15h 40m1 stop
$355Multiple Airlines
Sat, Dec 20 - Sat, Jan 3
Spirit Airlines Logo
3:10 pm - 11:29 pm
MDE
-
CLT
8h 19m1 stop
Spirit Airlines Logo
7:00 am - 2:14 pm
CLT
-
MDE
7h 14m1 stop
$362Spirit Airlines
Thu, Jan 15 - Tue, Jan 20
Spirit Airlines Logo
2:50 pm - 6:48 pm
MDE
-
CLT
27h 58m2 stops
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
$363Spirit Airlines
Fri, Dec 26 - Tue, Jan 13
Spirit Airlines Logo
11:50 am - 8:39 pm
MDE
-
CLT
8h 49m1 stop
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
$384Spirit Airlines
Wed, Mar 11 - Wed, Mar 18
Spirit Airlines Logo
2:10 pm - 12:40 am
MDE
-
CLT
9h 30m1 stop
Spirit Airlines Logo
1:24 pm - 12:36 am
CLT
-
MDE
12h 12m1 stop
$385Spirit Airlines
Sat, Dec 20 - Mon, Jan 5
Spirit Airlines Logo
3:10 pm - 11:29 pm
MDE
-
CLT
8h 19m1 stop
Spirit Airlines Logo
9:38 pm - 2:14 pm
CLT
-
MDE
16h 36m1 stop
$388Spirit Airlines
Sat, Dec 20 - Tue, Jan 6
Spirit Airlines Logo
3:10 pm - 11:29 pm
MDE
-
CLT
8h 19m1 stop
Spirit Airlines Logo
7:00 am - 2:14 pm
CLT
-
MDE
7h 14m1 stop
$390Spirit Airlines
Sat, Jan 24 - Sat, Jan 31
Multiple Airlines Logo
9:09 am - 12:40 am
MDE
-
CLT
15h 31m2 stops
Multiple Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
$391Multiple Airlines
Booking Insights

KAYAK's insights & trends for Medellín to South Carolina flights

Get data-powered insights and trends into flights from Medellín to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Medellín Jose Maria Cordova Intl Airport and South Carolina?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Medellín Jose Maria Cordova Intl Airport to South Carolina.

There is just one airline that flies from Medellín Jose Maria Cordova Intl Airport to South Carolina direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to Greenville (GSP) and costs $528.

Find deals

Good to know

Low seasonFebruary
Cheapest flight$194
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Medellín to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Medellín to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Medellín to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Medellín to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Medellín to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $691 on average. The most expensive time of day to fly to South Carolina is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $691.

Reviews of the top airline flying from Medellín to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Medellín to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11048 reviews
8.0Crew
6.9Entertainment
7.5Boarding
6.5Food
7.2Comfort
Airline reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

8.0 ExcellentConnie, Dec 2025
PHX - MKE
Read more American Airlines reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Everything you need to know for your flight from Medellín to South Carolina

Information on your arrival and departure airports

Medellín (MDE)