MFR - FSD

$344 Find Cheap Flights from Medford to Sioux Falls

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Sioux Falls departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sioux Falls

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Sioux Falls, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Sioux Falls, as well as popular online travel agencies
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Everything you should know

Cheapest one-way
$344
American Airlines
Tue 6/9
MFR - FSD • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Medford and Sioux Falls. You'll need at least 1 connection.
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Top layover airports
Phoenix (PHX)
Cheapest • Avg $576 (round-trip)
Denver (DEN)
Shortest trip • 5h 53m (one-way)
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Sioux Falls (MFR-FSD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Sioux Falls that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Sioux Falls

Multiple Airlines Logo
MFR
-
FSD
1317 mimulti-stop
Multiple Airlines Logo
FSD
-
MFR
1317 mimulti-stop
Multiple Airlines
Booking Insights

KAYAK's insights & trends for Medford to Sioux Falls flights

Get data-powered insights and trends into flights from Medford to Sioux Falls to help you find the cheapest flights, the best time to fly and much more.

What is the most popular layover airport when flying from Medford to Sioux Falls?

Percentage of 1-stop round-trip flights from Medford to Sioux Falls chosen by KAYAK users via each layover airport in the last 12 months (only includes trips with the same layover airport on both legs).

Denver (DEN) is the top choice – 73% of KAYAK users who clicked on 1-stop flights from Medford to Sioux Falls picked an itinerary connecting there.

What is the cheapest layover airport when flying from Medford to Sioux Falls?

Average round-trip price for 1-stop flights from Medford to Sioux Falls clicked by KAYAK users in the last 12 months (only includes trips with the same layover airport on both legs).

Flights via Phoenix (PHX) offer the most affordable fares, with an average round-trip price of $576.

Which layover airport offers the shortest total travel time from Medford to Sioux Falls?

Shortest average total travel time for 1-stop one-way flights from Medford to Sioux Falls via different layover airports, based on KAYAK user data from the last 12 months.

Consider flying via Denver (DEN) for the shortest journey. The average one-way travel time for flights connecting there is 5h 53m.

Which layover airport has the quickest connection when flying from Medford to Sioux Falls?

Average layover duration at different layover airports for 1-stop one-way flights from Medford to Sioux Falls, based on KAYAK user data from the last 12 months.

If you prefer a quick connection, Denver (DEN) often has the shortest layovers from Medford to Sioux Falls, with an average of 1h 34m.

Find deals

Good to know

Cheapest flight$344
Flight from Medford to Sioux Falls

When to book flights from Medford to Sioux Falls

Are your dates flexible? Find out the best times to travel from Medford to Sioux Falls based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to Sioux Falls

  • What is the cheapest flight from Medford to Sioux Falls?

    In the last 3 days, the lowest price for a flight from Medford to Sioux Falls was $344 for a one-way ticket.

  • Do I need a passport to fly between Medford and Sioux Falls?

    No

  • Which aircraft models fly most regularly from Medford to Sioux Falls?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medford to Sioux Falls?

    Star Alliance is the only airline alliance operating flights between Medford and Sioux Falls.

  • How does KAYAK find such low prices on flights from Medford to Sioux Falls?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to Sioux Falls.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to Sioux Falls?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sioux Falls from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to Sioux Falls?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sioux Falls with an airline and back to Medford with another airline. Booking your flights between Medford and FSD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to Sioux Falls?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sioux Falls from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medford to Sioux Falls

 
See real verified KAYAK customer reviews for airlines flying from Medford to Sioux Falls. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Sioux Falls? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9574 reviews
7.1Entertainment
7.7Boarding
7.3Comfort
8.1Crew
6.6Food
Airline reviews

Overall flight was ok. Flight attendant was receptive to assisting passengers with tight connections.

6.0 GoodAnonymous, Apr 2026
GPT - IAH
Read more United Airlines reviews

Overall flight was ok. Flight attendant was receptive to assisting passengers with tight connections.

Checking in united could not figure out my star alliance gold. Baggage did not get marked priority and didn't receive boarding passes. When got to SFO lounge personal fixed everything Immediately

Very comfortable flight, snacks and drinks were good, good communication from crew. Could have used a little more information on timing of boarding for group 5

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

This was the first flight in the morning. We boarded fine. The cabin door was closed and we were ready to go. We were notified by the Captain that ATC issued and ground stop for 40 minutes. So, without even pushing back from the gate, we were already 40 minutes late. We actually were released to push-back and taxi at 30 minutes. But, some passengers had tight connections and were not going to make their connections. Some passengers asked about the delay and the effect on the connections and were told by the cabin attendant that all flights will be delayed and so they should be OK. However, that was not true. My connecting flight was on time and I arrived at IAH with 21 minutes to make my connection. I did and I'm happy about that, but the flight crew should not have given assurances to the passengers who might have missed their connections.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

After arriving in Chicago, we were taxiing for 1.5 hours with infrequent and untruthful updates about the amount of time it would take to arrive at the gate. Minimally, the team could have provided timing expectations that were more truthful, especially one their original expectations were not met.

Flights were on time actually early service was good and crew cheerful

Every staff member was professional, friendly and courteous. The pizza twist was ok. It was warm but too much dough.

Everything you need to know for your flight from Medford to Sioux Falls

Information on your arrival and departure airports

Medford (MFR)
Sioux Falls (FSD)