MEX - PTY

$151 Find Cheap Flights from Mexico City to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Mexico City to Panama City (MEX-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Panama City

Thu, Oct 2 - Mon, Oct 6
Copa Airlines Logo
3:30 pm - 8:13 pmMEX-PTY
3h 43mnonstop
Copa Airlines Logo
9:26 am - 12:10 pmPTY-MEX
3h 44mnonstop
$319Copa Airlines
Find Deal
Sun, Sep 21 - Sat, Oct 4
Copa Airlines Logo
1:05 pm - 5:49 pmMEX-PTY
3h 44mnonstop
Copa Airlines Logo
10:21 pm - 1:00 amPTY-MEX
3h 39mnonstop
$320Copa Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 14
Copa Airlines Logo
3:30 pm - 8:13 pmMEX-PTY
3h 43mnonstop
Copa Airlines Logo
10:21 pm - 1:00 amPTY-MEX
3h 39mnonstop
$323Copa Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
Avianca Logo
11:15 pm - 4:55 pmMEX-PTY
16h 40m1 stop
Avianca Logo
2:55 am - 6:10 pmPTY-MEX
16h 15m1 stop
$325Avianca
Find Deal
Thu, Oct 2 - Mon, Oct 6
Copa Airlines Logo
3:30 pm - 8:13 pmMEX-PTY
3h 43mnonstop
Copa Airlines Logo
9:26 am - 12:10 pmPTY-MEX
3h 44mnonstop
$326Copa Airlines
Find Deal
Wed, Nov 19 - Thu, Nov 27
Aeromexico Logo
8:40 am - 1:32 pmMEX-PTY
3h 52mnonstop
Aeromexico Logo
2:36 pm - 5:35 pmPTY-MEX
3h 59mnonstop
$330Aeromexico
Find Deal
Mon, Sep 29 - Tue, Oct 7
Avianca Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
Avianca Logo
8:10 pm - 10:55 amPTY-MEX
15h 45m1 stop
$336Avianca
Find Deal
Fri, Dec 12 - Wed, Jan 7
Aeromexico Logo
8:40 am - 1:32 pmMEX-PTY
3h 52mnonstop
Aeromexico Logo
3:02 pm - 5:40 pmPTY-MEX
3h 38mnonstop
$356Aeromexico
Find Deal
Tue, Oct 7 - Tue, Oct 14
 Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
 Logo
3:40 pm - 9:45 pmPTY-MEX
7h 05m1 stop
Tue, Oct 7 - Tue, Oct 14
 Logo
12:40 am - 4:30 pmMEX-PTY
14h 50m1 stop
 Logo
3:40 pm - 9:45 pmPTY-MEX
7h 05m1 stop

Everything you should know

Our travelers' advice
AI-generated summary based on content written by travel experts
For departures at MEX, arrive 3 hours early.
At PTY, use authorized taxi stands for fair rates.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Copa Airlines
Cheapest • from $319 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 24% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
July
Cheapest • 17% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$319
Typical prices: $394-510
Copa Airlines
Thu 10/2Mon 10/6
MEX - PTY • Non-stop
Cheapest one-way
$151
Typical prices: $210-519
Avianca
Sat 9/20
MEX - PTY • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Expert advice

Expert advice for your flight from Mexico City to Panama City

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airports
MEX

For departures at MEX, arrive 3 hours early for international flights due to potentially long security lines.

Read more about MEXby Marisa Garcia
PTY

At PTY, use authorized taxi stands for fair rates to Panama City, avoiding haggling with drivers.

Read more about PTYby Mark Chesnut
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on MEX

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Booking Insights

KAYAK's insights & trends for Mexico City to Panama City flights

Get data-powered insights and trends into flights from Mexico City to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Mexico City to Panama City?

What’s the cheapest day of the week to fly from Mexico City to Panama City?

The average price of all round-trip flights from Mexico City to Panama City clicked on KAYAK for each day over the last 12 months.

For Mexico City to Panama City, Wednesday is the cheapest day to fly on average and Monday is the most expensive. Flying from Panama City back to Mexico City, the best deals are generally found on Tuesday, with Saturday being the most expensive.

What is the cheapest month to fly from Mexico City to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Panama City is July, where tickets cost $351 (return) on average. On the other hand, the most expensive months are December and September, where the average cost of round-trip tickets is $482 and $468 respectively.

Can I save money by flying with a layover from Mexico City to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $330, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Mexico City to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Panama City, you should book around 7 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$151
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from Mexico City to Panama City

When to book flights from Mexico City to Panama City

Are your dates flexible? Find out the best times to travel from Mexico City to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Panama City

  • Which airlines offer an eco-friendly journey on the Mexico City to Panama City route?

    Avianca Airlines is one of the airlines committed to offsetting carbon emissions by ensuring a 13% carbon reduction per passenger. This airline also collaborates with passengers to ensure a clean environment through voluntary contributions to reduce waste and conserve forest ecosystems. American Airlines also offers sustainable travel and is committed to attaining net-zero carbon emissions by recycling aluminum and using sustainable aviation fuel.

  • Are there allowances to upgrade to first class on flights from Mexico City to Panama City?

    You can upgrade to first class if you need a smooth journey on the Mexico City to Panama City route. Your airline can email you about the availability of seats and the amount you need to pay. The advantage of upgrading instead of originally booking a first class ticket is that it’s cheaper. The amount you pay depends on your airline and class fare. Also, most airlines require you to upgrade at least 24 hours before takeoff.

  • Which nearby cities are served by Panama Tocumen International Airport (PTY)?

    After arriving at PTY airport, you can visit a few nearby cities, including Cabra to the northeast, Cerro Azul to the north, La Cabima to the northwest, Ancon to the west, and Balboa to the southwest. You can get to your destination by using public transportation outside the airport or enjoying the flexibility of a rental car.

  • Are the origin and destination airports hubs for any airlines?

    Benito Juarez International Airport is a hub for Volaris, Interjet, and Aeromexico. This airport serves thousands of passengers daily, linking many domestic and international cities. At the same time, Panama Tocumen International Airport is a hub for Copa Airlines. This airport serves many North American, South American, and Caribbean cities.

  • What is the cheapest flight from Mexico City to Panama City?

    In the last 3 days, the lowest price for a flight from Mexico City to Panama City was $151 for a one-way ticket and $319 for a round-trip.

  • Do I need a passport to fly between Mexico City and Panama City?

    Yes

  • Which aircraft models fly most regularly from Mexico City to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Mexico City to Panama City flight route.

  • Which airline alliances offer flights from Mexico City to Panama City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Mexico City and Panama City, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Mexico City to Panama City?

    There are nonstop flights from Mexico City to Panama City on a daily basis.

  • Which is the best airline for flights from Mexico City to Panama City, Copa Airlines or Aeromexico?

    The two airlines most popular with KAYAK users for flights from Mexico City to Panama City are Copa Airlines and Aeromexico. With an average price for the route of $445 and an overall rating of 7.6, Copa Airlines is the most popular choice. Aeromexico is also a great choice for the route, with an average price of $330 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Mexico City to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Mexico City to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $240 or less one-way and $330 or less round-trip.
  • Copa Airlines provide special dietary options to travelers with medical, dietary, or religious needs on the Mexico City (MEX) to Panama City (PTY) route. However, you need to order at least 24 hours before departure by contacting the airline’s call center.
  • The carry-on and checked luggage allowance on cheap flights from Mexico City to Panama City varies from one airline to another. If you book American Airlines, your carry-on luggage shouldn't exceed 22 x 14 x 9 inches, and you can bring an additional checked bag weighing no more than 50 lbs.
  • Benito Juarez International Airport (MEX) is wheelchair accessible to ensure a smooth journey for passengers with limited mobility. The airport offers free transfer to travelers with disabilities and has accessible toilets and elevators.
  • Business class amenities to enjoy on cheap flights from Mexico City to Panama City include priority check-in, lounge access, additional luggage allowance, large legroom, luxury dining, and in-flight entertainment. However, some amenities depend on your airline.
  • One way to travel to MEX airport from downtown Mexico City is to take the Line 4 bus to arrive there in about 5 minutes. Another option is the Line 1 subway, which gets you to the airport in approximately 4 minutes. If you have a piece of heavy luggage, you can take a taxi to arrive in around 6 minutes.

Prefer to fly direct from Mexico City to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Mexico City Benito Juarez to Panama City Tocumen Intl.
Find which airlines fly direct from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Mexico City Benito Juarez to Panama City Tocumen Intl

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Mexico City Benito Juarez

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Mexico City to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1531 reviews
6.8Food
7.4Comfort
7.8Boarding
6.8Entertainment
8.1Crew
Airline reviews

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

10.0 ExcellentAnonymous, Aug 2025CTG - PTY
Read more Copa Airlines reviews

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

Good, the flight from Miami to Mexico City was better than Mexico City to Miami

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

the guy in front of me put his seat back immediately...and then left it back including thru landing and taxiing to the runway. attendants did not check/ask him to put it up for landing.

The airplane was an old airplane, seats were very uncomfortable and very little space, they changed my seat and that was no option to get back into my seat even when I was traveling a senior who required assistance.

This is not a low cost airline. Stop acting like o e.

Boarding, crew were excellent, food was ok and entertainment need to improve

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Excellent flight and one of the smoothest landing I’ve ever experienced

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

Everything you need to know for your flight from Mexico City to Panama City

Information on your arrival and departure airports

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