$161 Find Cheap Flights from Mexico City to Panama City - Compare and Save

Avianca Airlines is one of the airlines committed to offsetting carbon emissions by ensuring a 13% carbon reduction per passenger. This airline also collaborates with passengers to ensure a clean environment through voluntary contributions to reduce waste and conserve forest ecosystems. American Airlines also offers sustainable travel and is committed to attaining net-zero carbon emissions by recycling aluminum and using sustainable aviation fuel.

You can upgrade to first class if you need a smooth journey on the Mexico City to Panama City route. Your airline can email you about the availability of seats and the amount you need to pay. The advantage of upgrading instead of originally booking a first class ticket is that it’s cheaper. The amount you pay depends on your airline and class fare. Also, most airlines require you to upgrade at least 24 hours before takeoff.

After arriving at PTY airport, you can visit a few nearby cities, including Cabra to the northeast, Cerro Azul to the north, La Cabima to the northwest, Ancon to the west, and Balboa to the southwest. You can get to your destination by using public transportation outside the airport or enjoying the flexibility of a rental car.

Benito Juarez International Airport is a hub for Volaris, Interjet, and Aeromexico. This airport serves thousands of passengers daily, linking many domestic and international cities. At the same time, Panama Tocumen International Airport is a hub for Copa Airlines. This airport serves many North American, South American, and Caribbean cities.

Among airlines operating Mexico City to Panama City flights:

• Aeromexico: offers free seat selection
• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

2 airlines operate flights between Mexico City and Panama City. The airlines offering nonstop flights on this route include:

• Copa Airlines
• Aeromexico

Flights from Mexico City to Panama City usually depart from Mexico City Benito Juarez (MEX) and arrive at Panama City Tocumen Intl (PTY).

Here are some options for this route, based on selected ticket types and cabin classes:

• Aeromexico: a cabin bag and a checked bag in Economy Class
• Copa Airlines: a cabin bag and a checked bag in Economy Class
• AeroMexico Connect: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Three cabin classes are available on flights from Mexico City to Panama City:

• Economy Class
• Premium Economy Class
• Business Class

On this route, nonstop and layover fares are close on average, with nonstop at $409 round-trip and layover options via Bogotá El Dorado (BOG) at $395.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $60–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737 MAX 8 family is used most often on this route, operated mainly by Aeromexico and Copa Airlines. Other aircraft seen on the route include Boeing 737-800 variants.

One-stop flights from Mexico City to Panama City most commonly connect through:

• Bogotá El Dorado (BOG) - 51% of one-stop connections
• San Salvador El Salvador Intl (SAL) - 48% of one-stop connections
• Monterrey Gen Mariano Escobedo (MTY) - 0% of one-stop connections

Bogotá El Dorado (BOG) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 11% on the Mexico City to Panama City route. Thursday is the cheapest departure day at $390 round-trip on average, while Monday is the most expensive at $438, a difference of $48. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Mexico City to Panama City route, 4% of flights were delayed in the past 3 months, with delays averaging 2 hours 26 minutes.

Morning is the busiest departure period on Mexico City to Panama City flights, with 43% of flights leaving in that window. Afternoon departures account for 29%, night flights for 28%, and evening flights for 0%.

Some of the most popular sights in Panama City are Avenida Balboa, Multiplaza Pacific and ATLAPA Conventions Center. These are among the most viewed places in Panama City on KAYAK.

These are the earliest and latest flight times available from Mexico City to Panama City:

• Earliest: departs at 12:25 am and lands at 4:13 am
• Latest: departs at 3:30 pm and lands at 7:18 pm.

The flight takes about 3h 48m.

Last-minute fares on this route - booked within 2 weeks of departure - run 24% above the route average of $404. Book 6 weeks before departure for the lowest fares.

A nonstop flight from Mexico City to Panama City takes 3h 48m, covering 1,497 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $325 to $1,336. That means the highest observed fare was about 4x higher than the lowest one.

One-way fares from Mexico City to Panama City are currently lower than usual. Average one-way flight prices are about $243, which is 12% below the typical average for this route.

Copa Airlines is slightly above the route average for timely arrivals, while AeroMexico Connect has a lower on-time arrival rate. On-time arrival rates on Mexico City to Panama City flights are:

• Copa Airlines: 96% on time
• AeroMexico Connect: 95% on time
• Aeromexico: 93% on time

Overall, flights on this route are on time 96% of the time on average.

Night flights have the fewest delays on this route. Delays tend to pile up throughout the day as one late flight pushes the next, so earlier departures are usually more reliable.

Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time at 6h 59m, compared with 9h 37m via Bogotá El Dorado (BOG) and 11h 10m via Monterrey Gen Mariano Escobedo (MTY).

Panama City is 1 hour ahead of Mexico City (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:
· Avis
· Europcar
· Ace
· Budget
· Hertz

Round-trip flights from Mexico City to Panama City range from $348 to $511, with an average of $404 over the past 12 months. Anything below $348 counts as a good deal.