MEX - PTY

$151 Find Cheap Flights from Mexico City to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Panama City departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$343
Typical prices: $339-$423
Avianca
Fri 5/1Sat 5/9
MEX - PTY • 1 stop
Cheapest non-stop
$352
Typical prices: $395-$534
Copa Airlines
Thu 3/26Thu 4/2
MEX - PTY • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
For departures at MEX, arrive 3 hours early.
At PTY, use authorized taxi stands for fair rates.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Avianca
Cheapest • from $343 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 36% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
July
Cheapest • 7% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Mexico City to Panama City (MEX-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Panama City

Fri, May 1 - Sat, May 9
Avianca Logo
12:40 am - 2:15 pm
MEX
-
PTY
12h 35m
1 stop
Avianca Logo
3:10 pm - 11:00 pm
PTY
-
MEX
8h 50m
1 stop
$343Avianca
Sun, Mar 8 - Tue, Mar 10
Avianca Logo
12:40 am - 4:55 pm
MEX
-
PTY
15h 15m
1 stop
Avianca Logo
2:55 pm - 10:55 pm
PTY
-
MEX
9h 00m
1 stop
$345Avianca
Fri, Mar 6 - Sun, Mar 15
Avianca Logo
5:00 am - 4:55 pm
MEX
-
PTY
10h 55m
1 stop
Avianca Logo
7:50 pm - 1:15 am
PTY
-
MEX
6h 25m
1 stop
$346Avianca
Wed, Apr 15 - Tue, Apr 21
Avianca Logo
11:20 pm - 9:15 am
MEX
-
PTY
8h 55m
1 stop
Avianca Logo
10:10 am - 6:05 pm
PTY
-
MEX
8h 55m
1 stop
$347Avianca
Wed, Apr 15 - Sun, Apr 26
Avianca Logo
12:40 am - 2:15 pm
MEX
-
PTY
12h 35m
1 stop
Avianca Logo
3:10 pm - 3:05 am
PTY
-
MEX
12h 55m
1 stop
$349Avianca
Wed, Apr 8 - Sun, Apr 12
Avianca Logo
4:55 am - 5:00 pm
MEX
-
PTY
11h 05m
1 stop
Avianca Logo
5:30 am - 10:55 am
PTY
-
MEX
6h 25m
1 stop
$350Avianca
Thu, Mar 26 - Thu, Apr 2
Copa Airlines Logo
1:10 pm - 5:49 pm
MEX
-
PTY
3h 39mnonstop
Copa Airlines Logo
11:44 am - 2:30 pm
PTY
-
MEX
3h 46mnonstop
$352Copa Airlines
Sat, Feb 28 - Sun, Mar 29
Copa Airlines Logo
1:20 am - 5:54 am
MEX
-
PTY
3h 34mnonstop
Copa Airlines Logo
9:22 am - 12:10 pm
PTY
-
MEX
3h 48mnonstop
$358Copa Airlines
Wed, Apr 8 - Sat, Apr 18
Copa Airlines Logo
3:30 pm - 8:10 pm
MEX
-
PTY
3h 40mnonstop
Copa Airlines Logo
10:11 pm - 1:00 am
PTY
-
MEX
3h 49mnonstop
$359Copa Airlines
Tue, Mar 3 - Sun, Mar 29
Copa Airlines Logo
1:10 pm - 5:49 pm
MEX
-
PTY
3h 39mnonstop
Copa Airlines Logo
11:41 am - 2:30 pm
PTY
-
MEX
3h 49mnonstop
$361Copa Airlines
Booking Insights

KAYAK's insights & trends for Mexico City to Panama City flights

Get data-powered insights and trends into flights from Mexico City to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Mexico City to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Mexico City to Panama City departing in May.

What’s the cheapest day of the week to fly from Mexico City to Panama City?

The average price of all round-trip flights from Mexico City to Panama City clicked on KAYAK for each day over the last 12 months.

For Mexico City to Panama City, Wednesday is the cheapest day to fly on average and Friday is the most expensive. Flying from Panama City back to Mexico City, the best deals are generally found on Tuesday, with Sunday being the most expensive.

What is the cheapest month to fly from Mexico City to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Panama City is July, where tickets cost $351 (return) on average. On the other hand, the most expensive months are April and March, where the average cost of round-trip tickets is $418 and $407 respectively.

Can I save money by flying with a layover from Mexico City to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $405, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Mexico City to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Panama City, you should book around 5 weeks before departure, which saves you about 36% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Mexico City to Panama City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on MEX

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonJune
Cheapest flight$151
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Mexico City to Panama City

When to book flights from Mexico City to Panama City

Are your dates flexible? Find out the best times to travel from Mexico City to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Panama City

  • Which airlines offer an eco-friendly journey on the Mexico City to Panama City route?

    Avianca Airlines is one of the airlines committed to offsetting carbon emissions by ensuring a 13% carbon reduction per passenger. This airline also collaborates with passengers to ensure a clean environment through voluntary contributions to reduce waste and conserve forest ecosystems. American Airlines also offers sustainable travel and is committed to attaining net-zero carbon emissions by recycling aluminum and using sustainable aviation fuel.

  • Are there allowances to upgrade to first class on flights from Mexico City to Panama City?

    You can upgrade to first class if you need a smooth journey on the Mexico City to Panama City route. Your airline can email you about the availability of seats and the amount you need to pay. The advantage of upgrading instead of originally booking a first class ticket is that it’s cheaper. The amount you pay depends on your airline and class fare. Also, most airlines require you to upgrade at least 24 hours before takeoff.

  • Which nearby cities are served by Panama Tocumen International Airport (PTY)?

    After arriving at PTY airport, you can visit a few nearby cities, including Cabra to the northeast, Cerro Azul to the north, La Cabima to the northwest, Ancon to the west, and Balboa to the southwest. You can get to your destination by using public transportation outside the airport or enjoying the flexibility of a rental car.

  • Are the origin and destination airports hubs for any airlines?

    Benito Juarez International Airport is a hub for Volaris, Interjet, and Aeromexico. This airport serves thousands of passengers daily, linking many domestic and international cities. At the same time, Panama Tocumen International Airport is a hub for Copa Airlines. This airport serves many North American, South American, and Caribbean cities.

  • What is the cheapest flight from Mexico City to Panama City?

    In the last 3 days, the lowest price for a flight from Mexico City to Panama City was $151 for a one-way ticket and $343 for a round-trip.

  • Do I need a passport to fly between Mexico City and Panama City?

    Yes

  • Which aircraft models fly most regularly from Mexico City to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Mexico City to Panama City flight route.

  • Which airline alliances offer flights from Mexico City to Panama City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Mexico City and Panama City, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Mexico City to Panama City?

    There are nonstop flights from Mexico City to Panama City on a daily basis.

  • Which is the best airline for flights from Mexico City to Panama City, Copa Airlines or Aeromexico?

    The two airlines most popular with KAYAK users for flights from Mexico City to Panama City are Copa Airlines and Aeromexico. With an average price for the route of $417 and an overall rating of 7.5, Copa Airlines is the most popular choice. Aeromexico is also a great choice for the route, with an average price of $365 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Mexico City to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Mexico City to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $229 or less one-way and $358 or less round-trip.
  • Copa Airlines provide special dietary options to travelers with medical, dietary, or religious needs on the Mexico City (MEX) to Panama City (PTY) route. However, you need to order at least 24 hours before departure by contacting the airline’s call center.
  • The carry-on and checked luggage allowance on cheap flights from Mexico City to Panama City varies from one airline to another. If you book American Airlines, your carry-on luggage shouldn't exceed 22 x 14 x 9 inches, and you can bring an additional checked bag weighing no more than 50 lbs.
  • Benito Juarez International Airport (MEX) is wheelchair accessible to ensure a smooth journey for passengers with limited mobility. The airport offers free transfer to travelers with disabilities and has accessible toilets and elevators.
  • Business class amenities to enjoy on cheap flights from Mexico City to Panama City include priority check-in, lounge access, additional luggage allowance, large legroom, luxury dining, and in-flight entertainment. However, some amenities depend on your airline.
  • One way to travel to MEX airport from downtown Mexico City is to take the Line 4 bus to arrive there in about 5 minutes. Another option is the Line 1 subway, which gets you to the airport in approximately 4 minutes. If you have a piece of heavy luggage, you can take a taxi to arrive in around 6 minutes.

Prefer to fly direct from Mexico City to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Mexico City Benito Juarez to Panama City Tocumen Intl.
Find which airlines fly direct from Mexico City Benito Juarez Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Mexico City Benito Juarez to Panama City Tocumen Intl

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Mexico City Benito Juarez

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Mexico City to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1557 reviews
6.8Entertainment
7.4Comfort
8.1Crew
6.8Food
7.8Boarding
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Good, the flight from Miami to Mexico City was better than Mexico City to Miami

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

the guy in front of me put his seat back immediately...and then left it back including thru landing and taxiing to the runway. attendants did not check/ask him to put it up for landing.

only a bag of chips and a bottle of water in business class was served

Provide free food and drinks on an international flight. Add updated head rests

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Everything you need to know for your flight from Mexico City to Panama City

Information on your arrival and departure airports