PTY - MEX

$210 Find Cheap Flights from Panama City to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$316
Overall average: $417
Avianca
Thu 4/2Mon 4/6
PTY - MEX • 1 stop
Cheapest non-stop
$333
Typical prices: $417-$471
Aeromexico
Mon 3/16Mon 3/23
PTY - MEX • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
For a smooth departure, check your terminal at PTY.
Expect immigration at MEX to take 10-40 minutes.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Avianca
Cheapest • from $316 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 14% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
July
Cheapest • 11% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Mexico City (PTY-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Thu, Apr 2 - Mon, Apr 6
Avianca Logo
3:10 pm - 3:05 am
PTY
-
MEX
12h 55m
1 stop
Avianca Logo
12:40 am - 5:00 pm
MEX
-
PTY
15h 20m
1 stop
$316Avianca
Tue, Feb 24 - Sat, Feb 28
Avianca Logo
9:45 am - 6:10 pm
PTY
-
MEX
9h 25m
1 stop
Avianca Logo
11:10 pm - 8:50 am
MEX
-
PTY
8h 40m
1 stop
$322Avianca
Fri, Feb 13 - Fri, Feb 20
Avianca Logo
7:50 pm - 1:15 am
PTY
-
MEX
6h 25m
1 stop
Avianca Logo
5:00 am - 4:55 pm
MEX
-
PTY
10h 55m
1 stop
$324Avianca
Mon, Mar 16 - Mon, Mar 23
Aeromexico Logo
2:48 pm - 5:45 pm
PTY
-
MEX
3h 57mnonstop
Aeromexico Logo
8:55 am - 1:45 pm
MEX
-
PTY
3h 50mnonstop
$333Aeromexico
Sat, Feb 14 - Mon, Feb 16
Avianca Logo
7:50 pm - 11:20 am
PTY
-
MEX
16h 30m
1 stop
Avianca Logo
12:40 am - 2:00 pm
MEX
-
PTY
12h 20m
1 stop
$341Avianca
Sat, Feb 14 - Wed, Feb 18
Avianca Logo
7:50 pm - 11:20 am
PTY
-
MEX
16h 30m
1 stop
Avianca Logo
1:50 pm - 8:50 am
MEX
-
PTY
18h 00m
1 stop
$350Avianca
Tue, Feb 24 - Fri, Apr 24
Copa Airlines Logo
7:02 pm - 10:05 pm
PTY
-
MEX
4h 03mnonstop
Copa Airlines Logo
3:30 pm - 8:10 pm
MEX
-
PTY
3h 40mnonstop
$352Copa Airlines
Sat, Mar 14 - Sun, Mar 22
Avianca Logo
5:50 pm - 3:00 am
PTY
-
MEX
10h 10m
1 stop
Avianca Logo
5:00 am - 4:55 pm
MEX
-
PTY
10h 55m
1 stop
$353Avianca
Sat, May 30 - Sat, Jun 6
Aeromexico Logo
3:00 pm - 6:00 pm
PTY
-
MEX
4h 00mnonstop
Aeromexico Logo
9:00 am - 2:00 pm
MEX
-
PTY
4h 00mnonstop
$355Aeromexico
Mon, Apr 6 - Wed, Apr 15
Avianca Logo
3:05 am - 11:00 pm
PTY
-
MEX
20h 55m
1 stop
Avianca Logo
12:40 am - 9:15 am
MEX
-
PTY
7h 35m
1 stop
$365Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City flights

Get data-powered insights and trends into flights from Panama City to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Mexico City?

The average price of all round-trip flights from Panama City to Mexico City clicked on KAYAK for each day over the last 12 months.

For Panama City to Mexico City, Friday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Mexico City back to Panama City, the best deals are generally found on Wednesday, with Friday being the most expensive.

What is the cheapest month to fly from Panama City to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City is July, where tickets cost $342 (return) on average. On the other hand, the most expensive months are June and March, where the average cost of round-trip tickets is $429 and $417 respectively.

Can I save money by flying with a layover from Panama City to Mexico City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $364 on average.

How far in advance should I book a flight from Panama City to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Mexico City, you should book around 3 weeks before departure, which saves you about 14% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Mexico City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on MEX

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonMay
Cheapest flight$210
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Mexico City

  • Are there onsite hotels at Mexico City Benito Juarez Airport?

    Courtyard by Marriott Mexico City Airport is within walking distance of the airport. You can book a room and rest if you arrive at night or experience flight delays. Apart from beds, you can enjoy other amenities, including entertainment, meals, drinks, and a shower.

  • How can I travel from downtown Panama City to Panama City Tocumen International Airport?

    The quickest way to get to the airport is by taking a taxi. However, you can take a bus from Albrook Bus Terminal. You can also take a train at Metro de Panama if you prefer public transport.

  • Which is the most sustainable flight from Panama City to Mexico City?

    Copa Airlines use sustainable aviation fuel to reduce the impact of carbon on the environment. These airlines ensure a greener environment by upgrading fleets since 2000 and using RNAV satellite navigation for fuel conservation. Furthermore, these airlines ensure efficiency by optimizing taking off and landing, speed and attitude, convenient flight scheduling, and maintaining the planes. In addition, it has a recycling program and uses biodegradable products to improve environmental cleanliness.

  • Is there public transport to downtown Mexico City from MEX airport?

    You can take a train at line 5 subway that takes 39 minutes, a line 4 bus that takes about 52min, or a shuttle that takes about 50 minutes to get to the city. You can take the night bus at line 1 subway, about 38 minutes to the city if you're traveling late.

  • What is the cheapest flight from Panama City to Mexico City?

    In the last 3 days, the lowest price for a flight from Panama City to Mexico City was $210 for a one-way ticket and $316 for a round-trip.

  • Do I need a passport to fly between Panama City and Mexico City?

    A passport is required to fly from Panama City to Mexico City.

  • Which aircraft models fly most regularly from Panama City to Mexico City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Panama City to Mexico City flight route.

  • Which airline alliances offer flights from Panama City to Mexico City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Mexico City, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Mexico City?

    There are nonstop flights from Panama City to Mexico City on a daily basis.

  • Which is the best airline for flights from Panama City to Mexico City, Copa Airlines or Aeromexico?

    The two airlines most popular with KAYAK users for flights from Panama City to Mexico City are Copa Airlines and Aeromexico. With an average price for the route of $417 and an overall rating of 7.5, Copa Airlines is the most popular choice. Aeromexico is also a great choice for the route, with an average price of $345 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Panama City with another airline. Booking your flights between Panama City and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Mexico City

  • Looking for a cheap flight? 25% of our users found flights on this route for $388 or less one-way and $356 or less round-trip.
  • If you need to relax, enjoy a meal, or drink before your flight, you can rest at Panama City Tocumen International airport (PTY) lounges. If you're flying economy, you need to pay at the door, buy an annual pass, or purchase a day pass. The lounges include Tocumen Royal Saloon on the 3rd Floor, Copa Club on the 2nd floor, and The Lounge Panama near Gate 115.
  • Panama City Tocumen International Airport offers convenient car parking areas near the airport’s Main Terminal T1 and South Terminal T2. Alternatively, you can park your car on the off-site parking sites that are pocket-friendly and offer you a ride to your convenient airport terminal.
  • Mexico City Benito Juarez Airport (MEX) is a hub for Aeromexico, Volaris, and Aeromar. It also serves domestic and international flights. At the same time, Panama City Tocumen International Airport is a regional hub between North America, the Caribbean, and South America and a base for Copa Airlines.
  • There are car rentals available near Terminals 1 and 2 at Mexico City Benito Juarez Airport. You can choose a car you prefer from several car rentals, including Dollar, National, and E-Z Rent-A-Car. A valid driver's license is the most needed document when renting a car. However, you must be at least 21 years old to rent a vehicle.
  • When choosing flights from Panama City to Mexico City, you can book Copa Airlines if you need in-flight entertainment. You can enjoy music in various languages, including English, Spanish, and Portuguese. Again, you can enjoy your own entertainment through Copa Showpass.

Prefer to fly direct from Panama City to Mexico City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Mexico City Benito Juarez.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Mexico City Benito Juarez Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Mexico City Benito Juarez

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Direct returns

Mexico City Benito Juarez to Panama City Tocumen Intl

Monday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Tuesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Wednesday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Thursday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Friday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Saturday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

Sunday

Aeromexico, Copa Airlines

Aeromexico, Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Panama City to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
8.1Crew
7.8Boarding
6.8Food
7.4Comfort
6.8Entertainment
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Really nice, all good, nice crew and all on time

Unfortunately I had an awful boarding experience. Our first flight with Aeromexico was fine and landed on time however it couldn’t find a gate and we were late which made us lose our connecting flight with Aeromexico. The staff handled it horribly when we explained our situation and would not led us board when we missed the boarding time by a couple minutes. The staff were extremely rude and did not attempt to even help us. Because of this incident, my husband and I missed a full day of work which negatively impacted our salary which we need. Please compensate us for the work that we missed.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Provide free food and drinks on an international flight. Add updated head rests

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Everything you need to know for your flight from Panama City to Mexico City

Information on your arrival and departure airports