MEX - VVI

$582 Find Cheap Flights from Mexico City to Santa Cruz de la Sierra

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Santa Cruz de la Sierra departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$582
Typical prices: $495-$770
Copa Airlines
Wed 4/1Mon 4/6
MEX - VVI • 1 stop
Cheapest one-way
$2,757
Typical prices: $323-$528
United Airlines
Thu 2/5
MEX - VVI • 2 stops
Top airlines
Copa Airlines
Cheapest • from $582 (round-trip)
Avianca
Best reviews • 6.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 8% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 13% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico City to Santa Cruz de la Sierra (MEX-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Santa Cruz de la Sierra

Wed, Apr 1 - Mon, Apr 6
Copa Airlines Logo
5:50 am - 10:42 pm
MEX
-
VVI
14h 52m
1 stop
Copa Airlines Logo
1:15 am - 7:05 pm
VVI
-
MEX
19h 50m
1 stop
$582Copa Airlines
Wed, Mar 4 - Wed, Mar 11
Multiple Airlines Logo
8:25 pm - 4:35 am
MEX
-
VVI
30h 10m
2 stops
Multiple Airlines Logo
5:25 am - 8:05 pm
VVI
-
MEX
16h 40m
2 stops
$620Multiple Airlines
Mon, Apr 20 - Mon, Apr 27
Avianca Logo
2:00 pm - 1:50 am
MEX
-
VVI
9h 50m
1 stop
Avianca Logo
2:55 am - 1:55 am
VVI
-
MEX
25h 00m
2 stops
$632Avianca
Thu, Feb 5 - Thu, Apr 30
Multiple Airlines Logo
4:00 pm - 4:35 am
MEX
-
VVI
10h 35m
1 stop
Multiple Airlines Logo
5:25 am - 4:55 am
VVI
-
MEX
25h 30m
2 stops
$684Multiple Airlines
Thu, Feb 26 - Sat, Mar 21
Multiple Airlines Logo
4:00 pm - 4:35 am
MEX
-
VVI
10h 35m
1 stop
Multiple Airlines Logo
5:25 am - 8:05 pm
VVI
-
MEX
16h 40m
2 stops
$723Multiple Airlines
Fri, Feb 13 - Sat, Feb 21
Copa Airlines Logo
1:20 am - 10:50 pm
MEX
-
VVI
19h 30m
1 stop
Copa Airlines Logo
11:44 am - 10:05 pm
VVI
-
MEX
12h 21m
1 stop
$732Copa Airlines
Mon, Apr 20 - Sun, May 3
Avianca Logo
2:00 pm - 1:50 am
MEX
-
VVI
9h 50m
1 stop
Avianca Logo
2:55 am - 3:25 pm
VVI
-
MEX
14h 30m
2 stops
$755Avianca
Tue, Feb 3 - Tue, Feb 10
Multiple Airlines Logo
4:00 pm - 4:35 am
MEX
-
VVI
10h 35m
1 stop
Multiple Airlines Logo
5:20 am - 5:30 am
VVI
-
MEX
26h 10m
2 stops
$780Multiple Airlines
Tue, Feb 3 - Tue, Feb 10
Multiple Airlines Logo
4:00 pm - 4:35 am
MEX
-
VVI
10h 35m
1 stop
Multiple Airlines Logo
5:20 am - 5:30 am
VVI
-
MEX
26h 10m
2 stops
$781Multiple Airlines
Mon, Jul 6 - Sat, Jul 18
Copa Airlines Logo
5:50 am - 10:40 pm
MEX
-
VVI
14h 50m
1 stop
Copa Airlines Logo
1:12 am - 7:05 pm
VVI
-
MEX
19h 53m
1 stop
$834Copa Airlines
Booking Insights

KAYAK's insights & trends for Mexico City to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Mexico City to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Mexico City to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Mexico City to Santa Cruz de la Sierra departing in April.

What is the cheapest month to fly from Mexico City to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Santa Cruz de la Sierra is May, where tickets cost $530 (return) on average. On the other hand, the most expensive months are December and November, where the average cost of round-trip tickets is $818 and $678 respectively.

How far in advance should I book a flight from Mexico City to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Santa Cruz de la Sierra, you should book around 3 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$582
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly with an average 34% increase in price.
Flight from Mexico City to Santa Cruz de la Sierra

When to book flights from Mexico City to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Mexico City to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Santa Cruz de la Sierra

  • What is the cheapest flight from Mexico City to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Mexico City to Santa Cruz de la Sierra was $2,757 for a one-way ticket and $582 for a round-trip.

  • Do I need a passport to fly between Mexico City and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Mexico City and on arrival in Santa Cruz de la Sierra.

  • Which aircraft models fly most regularly from Mexico City to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Mexico City and Santa Cruz de la Sierra.

  • How does KAYAK find such low prices on flights from Mexico City to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Mexico City to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.6
AviancaOverall score based on 2495 reviews
6.2Comfort
5.4Entertainment
6.9Boarding
7.2Crew
5.0Food
Airline reviews

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

8.0 ExcellentFelipe, Jan 2026
MDE - BGA
Read more Avianca reviews

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Boarding, crew were excellent, food was ok and entertainment need to improve

Everything you need to know for your flight from Mexico City to Santa Cruz de la Sierra

Information on your arrival and departure airports