MEX - VVI

$495 Find Cheap Flights from Mexico City to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Santa Cruz de la Sierra departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$582
Typical prices: $496-$687
Copa Airlines
Mon 4/20Thu 4/30
MEX - VVI • 1 stop
Cheapest one-way
$495
Typical prices: $327-$444
Avianca
Mon 12/22
MEX - VVI • 2 stops
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 13% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 11% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico City to Santa Cruz de la Sierra (MEX-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Santa Cruz de la Sierra

Mon, Apr 20 - Thu, Apr 30
Copa Airlines Logo
1:20 am - 10:42 pmMEX-VVI
19h 22m1 stop
Copa Airlines Logo
11:44 am - 12:15 amVVI-MEX
14h 31m1 stop
$582Copa Airlines
Find Deal
Sat, Feb 7 - Sat, Feb 21
Copa Airlines Logo
2:00 am - 10:50 pmMEX-VVI
18h 50m1 stop
Copa Airlines Logo
1:15 am - 2:30 pmVVI-MEX
15h 15m1 stop
$602Copa Airlines
Find Deal
Sat, Feb 21 - Tue, Feb 24
Avianca Logo
11:10 pm - 2:35 amMEX-VVI
25h 25m1 stop
Avianca Logo
3:40 am - 10:55 pmVVI-MEX
21h 15m1 stop
$614Avianca
Find Deal
Tue, Mar 31 - Mon, Apr 6
Copa Airlines Logo
1:20 am - 10:42 pmMEX-VVI
19h 22m1 stop
Copa Airlines Logo
1:15 am - 12:10 pmVVI-MEX
12h 55m1 stop
$617Copa Airlines
Find Deal
Fri, Mar 13 - Sat, Mar 21
Copa Airlines Logo
1:20 am - 10:50 pmMEX-VVI
19h 30m1 stop
Copa Airlines Logo
11:42 am - 10:05 pmVVI-MEX
12h 23m1 stop
$628Copa Airlines
Find Deal
Fri, Jan 23 - Mon, Jan 26
Multiple Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
Multiple Airlines Logo
5:25 am - 8:05 pmVVI-MEX
16h 40m2 stops
$632Multiple Airlines
Find Deal
Tue, Mar 31 - Tue, Apr 7
Copa Airlines Logo
1:20 am - 10:42 pmMEX-VVI
19h 22m1 stop
Copa Airlines Logo
11:44 am - 1:00 amVVI-MEX
15h 16m1 stop
$634Copa Airlines
Find Deal
Sun, Apr 19 - Thu, Apr 23
Copa Airlines Logo
1:20 am - 3:40 amMEX-VVI
24h 20m1 stop
Copa Airlines Logo
1:15 am - 7:05 pmVVI-MEX
19h 50m1 stop
$637Copa Airlines
Find Deal
Fri, Feb 20 - Tue, Feb 24
Copa Airlines Logo
1:20 am - 10:50 pmMEX-VVI
19h 30m1 stop
Copa Airlines Logo
1:15 am - 2:30 pmVVI-MEX
15h 15m1 stop
$646Copa Airlines
Find Deal
Sat, Feb 21 - Wed, Feb 25
LATAM Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
LATAM Airlines Logo
5:25 am - 1:50 pmVVI-MEX
10h 25m1 stop
$683LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Mexico City to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Mexico City to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Mexico City to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Mexico City to Santa Cruz de la Sierra departing in April.

What’s the cheapest day of the week to fly from Mexico City to Santa Cruz de la Sierra?

The average price of all round-trip flights from Mexico City to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Mexico City to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Monday and avoiding Wednesdays for the best deals.

What is the cheapest month to fly from Mexico City to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Santa Cruz de la Sierra is May, where tickets cost $530 (return) on average. On the other hand, the most expensive months are November and December, where the average cost of round-trip tickets is $673 and $667 respectively.

How far in advance should I book a flight from Mexico City to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Santa Cruz de la Sierra, you should book around 5 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$495
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly with an average 11% increase in price.
Flight from Mexico City to Santa Cruz de la Sierra

When to book flights from Mexico City to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Mexico City to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Santa Cruz de la Sierra

  • What is the cheapest flight from Mexico City to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Mexico City to Santa Cruz de la Sierra was $495 for a one-way ticket and $582 for a round-trip.

  • Do I need a passport to fly between Mexico City and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Mexico City and on arrival in Santa Cruz de la Sierra.

  • Which aircraft models fly most regularly from Mexico City to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Mexico City and Santa Cruz de la Sierra.

  • How does KAYAK find such low prices on flights from Mexico City to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Mexico City to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.6
AviancaOverall score based on 2475 reviews
6.3Comfort
7.0Boarding
5.4Entertainment
5.1Food
7.2Crew
Airline reviews

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

4.0 OkayMichael, Oct 2025BOG - ORD
Read more Avianca reviews

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Boarding, crew were excellent, food was ok and entertainment need to improve

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Everything you need to know for your flight from Mexico City to Santa Cruz de la Sierra

Information on your arrival and departure airports