MEX - VVI

$453 Find Cheap Flights from Mexico City to Santa Cruz de la Sierra

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Santa Cruz de la Sierra departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santa Cruz de la Sierra, as well as popular online travel agencies
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Flights Deals

Cheap Flight Deals from Mexico City to Santa Cruz de la Sierra (MEX-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Mexico City to Santa Cruz de la Sierra

KAYAK's recommended round-trip deals from the most popular airlines that fly from Mexico City to Santa Cruz de la Sierra.
Discover the best prices for you by selecting your travel dates on KAYAK.
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3:10 pm - 4:35 amMEX-VVI
11h 25m1 stop
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5:20 am - 4:45 amVVI-MEX
25h 25m2 stops
Thu, Jun 19 - Thu, Jul 24
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9:15 am - 4:35 amMEX-VVI
17h 20m2 stops
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5:20 am - 1:50 pmVVI-MEX
10h 30m1 stop
Sat, Sep 27 - Fri, Oct 10
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12:25 am - 4:35 amMEX-VVI
26h 10m2 stops
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5:20 am - 5:05 amVVI-MEX
25h 45m2 stops
Tue, Sep 30 - Wed, Oct 15
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8:30 pm - 4:35 amMEX-VVI
30h 05m2 stops
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5:20 am - 5:05 amVVI-MEX
25h 45m2 stops
Sat, Sep 27 - Fri, Oct 10
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12:30 am - 4:35 amMEX-VVI
26h 05m2 stops
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5:20 am - 1:50 pmVVI-MEX
10h 30m1 stop
Wed, Jun 18 - Thu, Jul 24
Copa Airlines Logo
2:00 am - 10:13 pmMEX-VVI
18h 13m1 stop
Copa Airlines Logo
12:15 pm - 10:00 pmVVI-MEX
11h 45m1 stop
$729Copa Airlines
Find Deal
Wed, Jun 18 - Thu, Jul 24
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8:55 am - 4:35 amMEX-VVI
17h 40m2 stops
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5:20 am - 4:45 amVVI-MEX
25h 25m2 stops
Thu, Jun 19 - Thu, Jul 24
Copa Airlines Logo
1:40 am - 10:13 pmMEX-VVI
18h 33m1 stop
Copa Airlines Logo
1:09 am - 12:10 pmVVI-MEX
13h 01m1 stop
$839Copa Airlines
Find Deal
Fri, Jun 27 - Sat, Jul 12
Copa Airlines Logo
5:50 am - 10:13 pmMEX-VVI
14h 23m1 stop
Copa Airlines Logo
1:09 am - 12:10 pmVVI-MEX
13h 01m1 stop
$865Copa Airlines
Find Deal
Sat, Jun 28 - Sat, Jul 12
Copa Airlines Logo
5:50 am - 3:34 amMEX-VVI
19h 44m1 stop
Copa Airlines Logo
12:15 pm - 10:00 pmVVI-MEX
11h 45m1 stop
$876Copa Airlines
Find Deal
Fri, May 30 - Sat, Jun 28
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KAYAK's insights & trends for Mexico City to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Mexico City to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Mexico City to Santa Cruz de la Sierra?

The average price of all round-trip flights from Mexico City to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Mexico City to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Monday and avoiding Wednesdays for the best deals.

What is the cheapest month to fly from Mexico City to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Mexico City to Santa Cruz de la Sierra is May, where tickets cost $530 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $666 and $658 respectively.

How far in advance should I book a flight from Mexico City to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Mexico City to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Mexico City to Santa Cruz de la Sierra, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonFebruary
High seasonMay
Cheapest flight$453
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Mexico City to Santa Cruz de la Sierra

When to book flights from Mexico City to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Mexico City to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Santa Cruz de la Sierra

  • What is the cheapest flight from Mexico City to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Mexico City to Santa Cruz de la Sierra was $453 for a round-trip ticket.

  • Do I need a passport to fly between Mexico City and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Mexico City and on arrival in Santa Cruz de la Sierra.

  • Which aircraft models fly most regularly from Mexico City to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Mexico City to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Mexico City and Santa Cruz de la Sierra.

  • How does KAYAK find such low prices on flights from Mexico City to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top 3 airlines serving from Mexico City to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1769 reviews
7.6Boarding
7.4Comfort
8.1Crew
7.0Entertainment
6.7Food
Airline reviews

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

10.0 ExcellentRita, Apr 2025LIM - JFK
Read more LATAM Airlines reviews

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

We didn’t have any entertainment. I tried to go online without success. The airplane was extremely cold and they didn’t have blankets.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

reliable, relatively relaxed, helpful and kind staff and clean airplanes. No need for more.

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

Copa stranded us ans then tried to charge us thousands to leave Panama.

Friendly flight team and seamless travel from one stop to next.

I loved my experience. Very safe, Very informative and very friendly.

At JFK the Security line was extremely long and few checkpoints open.

Check in person said there would be lunch. We were first class passengers and lunch was chips.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Excellent flight and one of the smoothest landing I’ve ever experienced

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

So so, you feel like you have to pay for everything each time

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

Everything you need to know for your flight from Mexico City to Santa Cruz de la Sierra

Information on your arrival and departure airports

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