MEX - VVI

$526 Find Cheap Flights from Mexico City to Santa Cruz de la Sierra - Compare and Save

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Everything you should know

Cheapest round-trip
$594
Typical prices: $582-$830
LATAM Airlines
Mon 10/29Wed 11/14
MEX - VVI • 1 stop
Cheapest one-way
$526
Typical prices: $271-$364
Multiple Airlines
Tue 10/16
MEX - VVI • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Mexico City and Santa Cruz de la Sierra. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
11 weeks
in advance
Our data shows that travelers who book at least 11 weeks in advance save around 38% compared to booking last minute.
Insights
Insights
When to travel
August
Cheapest • 26% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Sao Paulo Guarulhos Intl (GRU)
Cheapest • Avg $520 (round-trip)
Lima J Chavez Intl (LIM)
Shortest trip • 10h 56m (one-way)
Insights
Insights
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We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico City to Santa Cruz de la Sierra (MEX-VVI)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Santa Cruz de la Sierra

Thu, Oct 29 - Sat, Nov 14
LATAM Airlines Logo
4:00 pm - 4:35 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
10h 35m1 stop Lima J Chavez Intl
LATAM Airlines Logo
5:30 am - 1:50 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
10h 20m1 stop Lima J Chavez Intl
$594LATAM Airlines
Thu, Oct 15 - Sat, Nov 14
Copa Airlines Logo
9:50 am - 10:44 pmMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
10h 54m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:08 am - 12:15 amVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
25h 07m1 stop Panama City Tocumen Intl
$623Copa Airlines
Wed, Nov 11 - Sun, Nov 29
Avianca Logo
8:20 am - 2:40 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 20m1 stop Bogotá El Dorado
Avianca Logo
3:45 am - 12:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
10h 30m1 stop Bogotá El Dorado
$648Avianca
Thu, Oct 15 - Sat, Nov 14
Avianca Logo
4:55 am - 2:30 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 35m1 stop Bogotá El Dorado
Avianca Logo
3:45 am - 10:55 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
21h 10m1 stop Bogotá El Dorado
$660Avianca
Tue, Dec 1 - Wed, Dec 30
Avianca Logo
8:20 am - 2:40 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 20m1 stop Bogotá El Dorado
Avianca Logo
3:45 am - 12:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
10h 30m1 stop Bogotá El Dorado
$669Avianca
Mon, Oct 12 - Sat, Nov 21
Copa Airlines Logo
2:10 am - 10:44 pmMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 34m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:41 am - 10:05 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
12h 24m1 stop Panama City Tocumen Intl
$670Copa Airlines
Fri, Feb 5 - Sun, Feb 7
Multiple Airlines Logo
4:00 pm - 4:35 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
10h 35m1 stop Lima J Chavez Intl
Multiple Airlines Logo
5:30 am - 5:30 amVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
26h 00m2 stops Lima J Chavez Intl Bogotá El Dorado
$679Multiple Airlines
Fri, Feb 26 - Fri, Mar 5
Multiple Airlines Logo
1:00 am - 4:35 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
25h 35m2 stops Bogotá El Dorado Lima J Chavez Intl
Multiple Airlines Logo
5:30 am - 10:30 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
19h 00m2 stops Lima J Chavez Intl Cancun
$680Multiple Airlines
Mon, Nov 30 - Wed, Jan 13
Avianca Logo
8:20 am - 2:40 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 20m1 stop Bogotá El Dorado
Avianca Logo
3:45 am - 12:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
10h 30m1 stop Bogotá El Dorado
$689Avianca
Tue, Nov 10 - Sun, Nov 29
Avianca Logo
12:30 am - 2:40 amMEX  Mexico City Benito Juarez-VVI Santa Cruz de la Sierra Viru Viru Intl
24h 10m1 stop Bogotá El Dorado
Avianca Logo
3:45 am - 5:15 amVVI  Santa Cruz de la Sierra Viru Viru Intl-MEX Mexico City Benito Juarez
27h 30m1 stop Bogotá El Dorado
$693Avianca
Booking Insights

Price, demand and travel trends for Mexico City to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Mexico City to Santa Cruz de la Sierra?

Round-trip flights from Mexico City to Santa Cruz de la Sierra typically range from $582 to $830. The lowest price found in the past 5 days was $594, on LATAM Airlines.

What's the cheapest day of the week to fly from Mexico City to Santa Cruz de la Sierra?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Mexico City to Santa Cruz de la Sierra. It’s 13% cheaper than the average day, while Saturday is the most expensive, with prices 28% higher.

What’s the cheapest month to fly from Mexico City to Santa Cruz de la Sierra?

•August is the cheapest month to fly from Mexico City to Santa Cruz de la Sierra at $509 round-trip.
•December ($841) and June ($814) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 65% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Mexico City to Santa Cruz de la Sierra the cheapest?

Flights from Mexico City to Santa Cruz de la Sierra are cheapest 11 weeks before departure. Booking in this window typically costs about 38% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Mexico City to Santa Cruz de la Sierra flights

Low season

September

Cheapest flight

$526
Beat the crowds with an average 24% drop in travelers.
The most popular month to fly with an average 309% increase in travelers.
One-way flight from Mexico City to Santa Cruz de la Sierra

When to book flights from Mexico City to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Mexico City to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Mexico City to Santa Cruz de la Sierra flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Mexico City to Santa Cruz de la Sierra?

    Only Economy Class is available on flights from Mexico City to Santa Cruz de la Sierra.

  • How long is a flight from Mexico City to Santa Cruz de la Sierra?

    A nonstop flight from Mexico City to Santa Cruz de la Sierra takes 00m, covering 3,534 miles.

  • Do I need a passport to fly from Mexico City to Santa Cruz de la Sierra?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Mexico City to Santa Cruz de la Sierra flight?

    Round-trip flights from Mexico City to Santa Cruz de la Sierra range from $582 to $830, with an average of $688 over the past 12 months. Anything below $582 counts as a good deal.

  • How expensive are last-minute Mexico City to Santa Cruz de la Sierra flights?

    Last-minute fares on this route (booked within two weeks of departure) run 14% above the $688 route average. Book 11 weeks before departure for the lowest fares.

  • Have flight prices from Mexico City to Santa Cruz de la Sierra changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $594 to $3,822. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Mexico City to Santa Cruz de la Sierra looking right now?

    One-way fares from Mexico City to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $580, which is 93% above the typical average for this route.

  • Which airports can I use when flying from Mexico City to Santa Cruz de la Sierra?

    Flights from Mexico City to Santa Cruz de la Sierra usually depart from Mexico City Benito Juarez (MEX) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

  • Which airports do connecting flights from Mexico City to Santa Cruz de la Sierra pass through?

    One-stop flights from Mexico City to Santa Cruz de la Sierra most commonly connect through:

    • Bogotá El Dorado (BOG) - 39% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 35% of one-stop connections
    • Lima J Chavez Intl (LIM) - 24% of one-stop connections
    • Sao Paulo Guarulhos Intl (GRU) - 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Mexico City to Santa Cruz de la Sierra?

    Yes. Flexible dates can save you up to 32% on flights from Mexico City to Santa Cruz de la Sierra. Tuesday is the cheapest departure day at $605 round-trip on average, while Saturday is the most expensive at $882, a difference of $277.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Mexico City to Santa Cruz de la Sierra?

    Flying via Lima J Chavez Intl (LIM) gives the shortest average 1-stop total travel time at 10h 56m, compared with 12h 53m via Bogotá El Dorado (BOG) and 13h 41m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Mexico City and Santa Cruz de la Sierra?

    Santa Cruz de la Sierra is 2 hours ahead of Mexico City (Bolivia Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Mexico City to Santa Cruz de la Sierra flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Saturday. On this route, Tuesday flights average $605, about $277 less than Saturday fares (31% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 11 weeks before you fly. On this route, that window historically saves about 38% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Mexico City to Santa Cruz de la Sierra trip for August. Fares historically average $509 round-trip in that month - typically $332 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.

    • Sun Hotel

More options for your flight from Mexico City to Santa Cruz de la Sierra

Complete your trip to Santa Cruz de la Sierra with a hotel stay or car rental

Car rentals in Santa Cruz de la Sierra
Hotels in Santa Cruz de la Sierra