VVI - MEX

$373 Find Cheap Flights from Santa Cruz de la Sierra to Mexico City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Mexico City departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$616
Typical prices: $568-$715
Multiple Airlines
Thu 9/10Wed 9/23
VVI - MEX • 1 stop
Cheapest one-way
$373
Typical prices: $417-$848
Copa Airlines
Tue 10/6
VVI - MEX • 1 stop
Top airlines
Cheapest • from $666 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Cruz de la Sierra and Mexico City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $763 (round-trip)
Shortest trip • 10h 27m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 14% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
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We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to Mexico City (VVI-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to Mexico City

Thu, Sep 10 - Wed, Sep 23
Multiple Airlines Logo
12:15 pm - 4:10 pm
VVI
-
MEX
29h 55m
1 stop
Multiple Airlines Logo
6:40 pm - 11:20 am
MEX
-
VVI
14h 40m
1 stop
$616Multiple Airlines
Mon, Sep 28 - Wed, Oct 7
Multiple Airlines Logo
12:15 pm - 4:10 pm
VVI
-
MEX
29h 55m
1 stop
Multiple Airlines Logo
6:40 pm - 11:10 am
MEX
-
VVI
14h 30m
1 stop
$633Multiple Airlines
Mon, Sep 28 - Tue, Oct 6
Multiple Airlines Logo
12:15 pm - 4:10 pm
VVI
-
MEX
29h 55m
1 stop
Multiple Airlines Logo
6:40 pm - 11:10 am
MEX
-
VVI
14h 30m
1 stop
$633Multiple Airlines
Mon, Sep 28 - Wed, Oct 7
LATAM Airlines Logo
5:25 am - 1:50 pm
VVI
-
MEX
10h 25m
1 stop
LATAM Airlines Logo
3:10 pm - 4:35 am
MEX
-
VVI
11h 25m
1 stop
$666LATAM Airlines
Mon, Sep 28 - Wed, Oct 7
LATAM Airlines Logo
5:25 am - 1:50 pm
VVI
-
MEX
10h 25m
1 stop
LATAM Airlines Logo
3:10 pm - 4:35 am
MEX
-
VVI
11h 25m
1 stop
$671LATAM Airlines
Thu, Aug 13 - Thu, Aug 27
Copa Airlines Logo
1:12 am - 7:05 pm
VVI
-
MEX
19h 53m
1 stop
Copa Airlines Logo
5:50 am - 10:40 pm
MEX
-
VVI
14h 50m
1 stop
$690Copa Airlines
Wed, Nov 11 - Tue, Dec 1
Copa Airlines Logo
1:08 am - 7:20 pm
VVI
-
MEX
20h 12m
1 stop
Copa Airlines Logo
3:30 pm - 3:42 am
MEX
-
VVI
10h 12m
1 stop
$690Copa Airlines
Sun, Nov 8 - Sat, Nov 14
Avianca Logo
3:40 am - 12:10 pm
VVI
-
MEX
10h 30m
1 stop
Avianca Logo
1:50 pm - 2:35 am
MEX
-
VVI
10h 45m
1 stop
$704Avianca
Sun, Oct 4 - Mon, Oct 12
Avianca Logo
3:35 am - 12:10 pm
VVI
-
MEX
10h 35m
1 stop
Avianca Logo
2:00 pm - 2:30 am
MEX
-
VVI
10h 30m
1 stop
$722Avianca
Mon, Sep 28 - Wed, Oct 7
LATAM Airlines Logo
5:25 am - 9:30 am
VVI
-
MEX
30h 05m
2 stops
LATAM Airlines Logo
3:10 pm - 4:35 am
MEX
-
VVI
11h 25m
1 stop
$780LATAM Airlines
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to Mexico City flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to Mexico City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Cruz de la Sierra to Mexico City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Cruz de la Sierra to Mexico City departing in September.

Flight prices are below average for this route right now.

Flights to Mexico City from Santa Cruz de la Sierra usually cost between $654 and $801 in September.
The lowest price found in the past 5 days was $616 on Multiple Airlines (Sep 10-Sep 23).

What is the cheapest month to fly from Santa Cruz de la Sierra to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to Mexico City is November, where tickets cost $608 (return) on average. On the other hand, the most expensive months are June and January, where the average cost of round-trip tickets is $890 and $749 respectively.

How far in advance should I book a flight from Santa Cruz de la Sierra to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santa Cruz de la Sierra to Mexico City, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low season

January

Cheapest flight

$373
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Santa Cruz de la Sierra to Mexico City

When to book flights from Santa Cruz de la Sierra to Mexico City

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to Mexico City

  • What is the cheapest flight from Santa Cruz de la Sierra to Mexico City?

    In the last 5 days, the lowest price for a flight from Santa Cruz de la Sierra to Mexico City was $373 for a one-way ticket and $616 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and Mexico City?

    A passport is required to fly from Santa Cruz de la Sierra to Mexico City.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to Mexico City?

    Star Alliance is the only airline alliance operating flights between Santa Cruz de la Sierra and Mexico City.

  • Which is the best airline for flights from Santa Cruz de la Sierra to Mexico City, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to Mexico City are Copa Airlines and LATAM Airlines. With an average price for the route of $821 and an overall rating of 7.6, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $774 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Cruz de la Sierra to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1564 reviews
6.9Food
6.8Entertainment
8.1Crew
7.8Boarding
7.4Comfort
Airline reviews

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

10.0 ExcellentAnonymous, Sep 2025
JFK - PTY
Read more Copa Airlines reviews

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

Have veg meal going forward . Other than e everything was excellent !!!

Seemed roomier than most US domestic airlines and they served food.

This airline doesn’t five and dime you for everything. I do think that a checked bag should be included in every fare.

This was my first time flying Copa but I'll definitely be back! Great service, professional agents, and delicious food for a fair price. Thanks for a great trip!

More information is needed on travel Requirements in the check in website

la atencion en el avion fue excelente, la facilidad del checkin es muy buena.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

reliable, relatively relaxed, with helpful staff in all 8 flights we had on this trip. They are solid even though we did not have special seating or status for the flights.

Very slow boarding, 1 hour late - uncomfortable chairs and crew barely speaking english even at the airport!

The Flight was delayed in 2,5 hours. 1 hour inside the airplane then we passangers were not allowed to receive food as the local regulariam determines (for delays bigger than 2 hours)

On time. At least they offer a drink and a small snack. Plane was clean

For bus boarding, group 1 should have been sent on a separate bus ahead of the general boarding. It would have been nice.

Not very good, they nickel & dime you for better seats & pay extra for the checking in bag, bad service all the way around

This airline is full of junk fees. After paying to get my kids to sit with me, we were asked at the gate to check in our roller bags and pay $40 for each one. Peruvian passengers all took their roller bag in the plane. I don’t appreciate airlines who spot the gringos to tax them more.

only a bag of chips and a bottle of water in business class was served

No food, terms when selling are not clear. To pricy for the service in general

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

I expected the plane to be as the one I took from manaos to Bogota and unfortunately it wasn’t as nice, the sits didn’t recline and there was not onboard entertainment.

i was charged $140.00usd for my backpack the only luggage i had was my backpack

I don't think anyone actually reads these comments, so I won't spend much time on this submission. If you want to talk, you know how to reach me. The D/FW manager of Avianca (self-identified), Juan Calderon, insisted I buy an onward ticket from San Salvador even though I have diplomatic status in El Salvador and live here. It cost me $1,393 and Mr Calderon would not let me make the ticked flexible so I could get a refund. He went out of his way to be rude to me. He gave me seat 32K -- windowless window seat in the last row and did not offer to let me upgrade even though there were plenty of seats. I have flown well over a million miles in my life and this is the worst experience I have ever had. I would like a refund on the ticket I was forced to buy. Just awful!

The temperature was cold and the food that we had to pay for was awful. The crew didn’t even offer a free glass of water. It was a long, expensive and uncomfortable flight.

Delay almost an hour which meant when we got to Guatemala there where 3 flights at the same time, you can imagine the caos in customs, avianca doesn’t care about passengers or schedules

Every food and beverage has to be paid and the seat was not confortable. They even gave water.

Avianca: you pay for a high-end flight and you fly like a low (very low) cost!

Everything you need to know for your flight from Santa Cruz de la Sierra to Mexico City

Information on your arrival and departure airports