VVI - MEX

$385 Find Cheap Flights from Santa Cruz de la Sierra to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Mexico City departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Mexico City, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$558
Overall average: $649
Copa Airlines
Tue 11/18Wed 11/26
VVI - MEX • 1 stop
Cheapest one-way
$385
Typical prices: $387-836
Avianca
Tue 10/21
VVI - MEX • 1 stop
Top airlines
Copa Airlines
Cheapest • from $558 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 8% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to Mexico City (VVI-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to Mexico City

Tue, Nov 18 - Wed, Nov 26
Copa Airlines Logo
11:40 am - 1:00 amVVI-MEX
15h 20m1 stop
Copa Airlines Logo
9:25 am - 10:46 pmMEX-VVI
11h 21m1 stop
$558Copa Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 28
Copa Airlines Logo
1:09 am - 2:30 pmVVI-MEX
15h 21m1 stop
Copa Airlines Logo
3:30 pm - 3:36 amMEX-VVI
10h 06m1 stop
$600Copa Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Copa Airlines Logo
11:40 am - 1:00 amVVI-MEX
15h 20m1 stop
Copa Airlines Logo
5:55 am - 10:46 pmMEX-VVI
14h 51m1 stop
$611Copa Airlines
Find Deal
Mon, Nov 3 - Mon, Nov 17
Copa Airlines Logo
1:09 am - 2:30 pmVVI-MEX
15h 21m1 stop
Copa Airlines Logo
2:00 am - 10:46 pmMEX-VVI
18h 46m1 stop
$623Copa Airlines
Find Deal
Wed, Nov 5 - Wed, Nov 12
Multiple Airlines Logo
5:25 am - 8:15 pmVVI-MEX
16h 50m2 stops
Multiple Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
$652Multiple Airlines
Find Deal
Wed, Dec 24 - Thu, Jan 1
LATAM Airlines Logo
5:25 am - 1:50 pmVVI-MEX
10h 25m1 stop
LATAM Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
$681LATAM Airlines
Find Deal
Tue, Feb 10 - Tue, Feb 17
Multiple Airlines Logo
5:25 am - 5:40 amVVI-MEX
26h 15m2 stops
Multiple Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
$686Multiple Airlines
Find Deal
Wed, Dec 24 - Tue, Dec 30
LATAM Airlines Logo
5:25 am - 1:50 pmVVI-MEX
10h 25m1 stop
LATAM Airlines Logo
4:00 pm - 4:35 amMEX-VVI
10h 35m1 stop
$708LATAM Airlines
Find Deal
Tue, Dec 23 - Wed, Dec 31
Avianca Logo
3:40 am - 10:55 pmVVI-MEX
21h 15m1 stop
Avianca Logo
5:00 am - 2:35 amMEX-VVI
19h 35m1 stop
$755Avianca
Find Deal
Tue, Oct 28 - Sun, Nov 30
Avianca Logo
3:40 am - 6:10 pmVVI-MEX
16h 30m1 stop
Avianca Logo
1:50 pm - 2:35 amMEX-VVI
10h 45m1 stop
$792Avianca
Find Deal
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to Mexico City flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santa Cruz de la Sierra to Mexico City?

The average price of all round-trip flights from Santa Cruz de la Sierra to Mexico City clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Mexico City on a Monday, as we generally find the cheapest rates on that day for this route. On the other hand, Wednesday is the most expensive day to fly from Santa Cruz de la Sierra to Mexico City. For your return ticket, we recommend flying on a Sunday and avoiding Tuesdays for the best deals.

What is the cheapest month to fly from Santa Cruz de la Sierra to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to Mexico City is September, where tickets cost $608 (return) on average. On the other hand, the most expensive months are January and July, where the average cost of round-trip tickets is $788 and $683 respectively.

How far in advance should I book a flight from Santa Cruz de la Sierra to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santa Cruz de la Sierra to Mexico City, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$385
Best time to beat the crowds with an average 1% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Santa Cruz de la Sierra to Mexico City

When to book flights from Santa Cruz de la Sierra to Mexico City

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to Mexico City

  • What is the cheapest flight from Santa Cruz de la Sierra to Mexico City?

    In the last 3 days, the lowest price for a flight from Santa Cruz de la Sierra to Mexico City was $385 for a one-way ticket and $558 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and Mexico City?

    A passport is required to fly from Santa Cruz de la Sierra to Mexico City.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to Mexico City?

    Star Alliance is the only airline alliance operating flights between Santa Cruz de la Sierra and Mexico City.

  • Which is the best airline for flights from Santa Cruz de la Sierra to Mexico City, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to Mexico City are Copa Airlines and LATAM Airlines. With an average price for the route of $675 and an overall rating of 7.6, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $781 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Cruz de la Sierra to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1542 reviews
7.8Boarding
8.1Crew
7.4Comfort
6.8Entertainment
6.8Food
Airline reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

10.0 ExcellentMichael, Sep 2025PBM - PTY
Read more Copa Airlines reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

The boarding and new bag drop-off process was confusing and causing massive delays.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

The chicken that was served in business class was cold!

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Excellent flight and one of the smoothest landing I’ve ever experienced

Everything you need to know for your flight from Santa Cruz de la Sierra to Mexico City

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.