VVI - MEX

$315 Find Cheap Flights from Santa Cruz de la Sierra to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Mexico City departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$545
Typical prices: $784-$627
Copa Airlines
Wed 5/20Tue 5/26
VVI - MEX • 1 stop
Cheapest one-way
$315
Typical prices: $320-$488
Copa Airlines
Mon 5/18
VVI - MEX • 1 stop
Top airlines
Cheapest • from $545 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Cruz de la Sierra and Mexico City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $666 (round-trip)
Shortest trip • 10h 29m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 9% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to Mexico City (VVI-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to Mexico City

Wed, May 20 - Tue, May 26
Copa Airlines Logo
1:12 am - 7:05 pm
VVI
-
MEX
19h 53m
1 stop
Copa Airlines Logo
12:25 am - 10:38 pm
MEX
-
VVI
20h 13m
1 stop
$545Copa Airlines
Mon, Jun 1 - Sat, Jun 6
Copa Airlines Logo
11:47 am - 1:00 am
VVI
-
MEX
15h 13m
1 stop
Copa Airlines Logo
1:20 am - 10:38 pm
MEX
-
VVI
19h 18m
1 stop
$625Copa Airlines
Thu, Jun 4 - Fri, Jun 19
Copa Airlines Logo
11:47 am - 12:15 am
VVI
-
MEX
14h 28m
1 stop
Copa Airlines Logo
5:50 am - 10:38 pm
MEX
-
VVI
14h 48m
1 stop
$648Copa Airlines
Mon, Sep 28 - Tue, Oct 6
Multiple Airlines Logo
12:00 pm - 4:10 pm
VVI
-
MEX
30h 10m
1 stop
Multiple Airlines Logo
6:40 pm - 11:10 am
MEX
-
VVI
14h 30m
1 stop
$661Multiple Airlines
Tue, May 26 - Sun, May 31
Copa Airlines Logo
11:47 am - 10:05 pm
VVI
-
MEX
12h 18m
1 stop
Copa Airlines Logo
1:20 am - 10:38 pm
MEX
-
VVI
19h 18m
1 stop
$662Copa Airlines
Thu, May 14 - Fri, May 22
Copa Airlines Logo
1:12 am - 7:05 pm
VVI
-
MEX
19h 53m
1 stop
Copa Airlines Logo
1:10 pm - 3:31 am
MEX
-
VVI
12h 21m
1 stop
$663Copa Airlines
Sun, Aug 23 - Mon, Aug 31
Multiple Airlines Logo
12:00 pm - 4:15 pm
VVI
-
MEX
30h 15m
1 stop
Multiple Airlines Logo
6:45 pm - 11:10 am
MEX
-
VVI
14h 25m
1 stop
$670Multiple Airlines
Sun, May 31 - Wed, Jun 17
Multiple Airlines Logo
12:45 pm - 4:20 pm
VVI
-
MEX
29h 35m
1 stop
Multiple Airlines Logo
6:40 pm - 11:10 am
MEX
-
VVI
14h 30m
1 stop
$684Multiple Airlines
Tue, May 5 - Thu, May 7
Copa Airlines Logo
11:47 am - 10:05 pm
VVI
-
MEX
12h 18m
1 stop
Copa Airlines Logo
1:20 am - 10:38 pm
MEX
-
VVI
19h 18m
1 stop
$685Copa Airlines
Sun, May 3 - Sat, May 16
Avianca Logo
3:35 am - 12:10 pm
VVI
-
MEX
10h 35m
1 stop
Avianca Logo
2:00 pm - 2:30 am
MEX
-
VVI
10h 30m
1 stop
$701Avianca
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to Mexico City flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to Mexico City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Cruz de la Sierra to Mexico City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Cruz de la Sierra to Mexico City departing in May.

What is the cheapest month to fly from Santa Cruz de la Sierra to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to Mexico City is September, where tickets cost $607 (return) on average. On the other hand, the most expensive months are January and March, where the average cost of round-trip tickets is $734 and $702 respectively.

How far in advance should I book a flight from Santa Cruz de la Sierra to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Cruz de la Sierra to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santa Cruz de la Sierra to Mexico City, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$315
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Santa Cruz de la Sierra to Mexico City

When to book flights from Santa Cruz de la Sierra to Mexico City

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to Mexico City

  • What is the cheapest flight from Santa Cruz de la Sierra to Mexico City?

    In the last 3 days, the lowest price for a flight from Santa Cruz de la Sierra to Mexico City was $315 for a one-way ticket and $545 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and Mexico City?

    A passport is required to fly from Santa Cruz de la Sierra to Mexico City.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to Mexico City?

    Star Alliance is the only airline alliance operating flights between Santa Cruz de la Sierra and Mexico City.

  • Which is the best airline for flights from Santa Cruz de la Sierra to Mexico City, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to Mexico City are Copa Airlines and LATAM Airlines. With an average price for the route of $944 and an overall rating of 7.5, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $808 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Cruz de la Sierra to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1581 reviews
7.8Boarding
6.8Food
7.4Comfort
8.1Crew
6.8Entertainment
Airline reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

10.0 ExcellentAnonymous, Apr 2026
DAV - PTY
Read more Copa Airlines reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Good check in process Poor information on payments at Lima airport

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

I had bad experiences before now was excellent I am glad they have business class again

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Everything you need to know for your flight from Santa Cruz de la Sierra to Mexico City

Information on your arrival and departure airports