$587 Find Cheap Flights from Mexico to Knoxville - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight to Knoxville departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Mexico to Knoxville

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico to Knoxville

Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
6:00 am - 11:59 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
16h 59m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl
United Airlines Logo
5:15 pm - 8:57 pmTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
28h 42m1 stop Houston George Bush Intcntl
$587United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
12:49 pm - 8:54 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
31h 05m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:35 pm - 11:49 amTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
17h 14m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
$607United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
12:49 pm - 8:54 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
31h 05m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:35 pm - 11:49 amTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
17h 14m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
$609United Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
12:06 pm - 8:52 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
6h 46m1 stop Dallas/Fort Worth
American Airlines Logo
5:35 pm - 10:57 amTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
19h 22m1 stop Dallas/Fort Worth
$625American Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
12:06 pm - 12:30 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
22h 24m2 stops Dallas/Fort Worth Chicago O'Hare Intl
American Airlines Logo
4:48 pm - 10:57 amTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
20h 09m2 stops Chicago O'Hare Intl Dallas/Fort Worth
$630American Airlines
Sun, Sep 6 - Thu, Sep 10
United Airlines Logo
6:50 am - 4:58 pmMLM  Morelia-TYS Knoxville McGhee Tyson
32h 08m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
9:45 am - 6:13 pmTYS  Knoxville McGhee Tyson-MLM Morelia
10h 28m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
$735United Airlines
Sun, Sep 6 - Thu, Sep 10
United Airlines Logo
6:50 am - 8:53 pmMLM  Morelia-TYS Knoxville McGhee Tyson
36h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
7:00 am - 6:13 pmTYS  Knoxville McGhee Tyson-MLM Morelia
13h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$736United Airlines
Fri, Dec 18 - Sun, Jan 3
American Airlines Logo
6:10 am - 11:41 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
16h 31m1 stop Dallas/Fort Worth
American Airlines Logo
5:30 am - 12:14 pmTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
7h 44m1 stop Dallas/Fort Worth
$743American Airlines
Fri, Dec 18 - Sun, Jan 3
American Airlines Logo
6:10 am - 11:41 pmSLP  San Luis Potosi-TYS Knoxville McGhee Tyson
16h 31m1 stop Dallas/Fort Worth
American Airlines Logo
6:38 am - 11:03 pmTYS  Knoxville McGhee Tyson-SLP San Luis Potosi
17h 25m2 stops Charlotte Douglas Dallas/Fort Worth
$747American Airlines
Sun, Sep 6 - Thu, Sep 10
United Airlines Logo
6:50 am - 6:17 pmMLM  Morelia-TYS Knoxville McGhee Tyson
9h 27m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 6:13 pmTYS  Knoxville McGhee Tyson-MLM Morelia
13h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$754United Airlines
Booking Insights

KAYAK's insights & trends for flights to Knoxville

Get data-powered insights and trends for flights to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How many direct flights to Knoxville are there each day?

There are around 195 direct flights from within Mexico to Knoxville every day. Most flights depart in the afternoon, with 33% of flights departing in the afternoon.

Good to know

Low season

March
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 14% lower on average.

FAQs - booking Knoxville flights

  • How far is Knoxville McGhee Tyson Airport from central Knoxville?

    The distance between Knoxville McGhee Tyson Airport and downtown Knoxville is 11 miles.

  • What is the name of Knoxville’s airport?

    There is only 1 airport in Knoxville, called Knoxville McGhee Tyson Airport (TYS). It can also be referred to as Mc Ghee Tyson or McGhee Tyson.

  • How does KAYAK find such low prices on flights to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to Knoxville are there each week?

    Each week there are around 1,362 direct flights from within Mexico to Knoxville. The most common day for departures is Sunday, with 17% of flights taking off on this day.

Top tips for finding cheap flights to Knoxville

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Knoxville flight deals.

Reviews of the top airline flying from Mexico to Knoxville

 
See real verified KAYAK customer reviews for airlines flying to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Mexico to Knoxville. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 10108 reviews
7.1Entertainment
7.7Boarding
8.1Crew
6.7Food
7.3Comfort
Airline reviews

It's fine but Newark to Nashville was too long

8.0 ExcellentAnonymous, Jul 2026
Read more United Airlines reviews

It's fine but Newark to Nashville was too long

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

We had excellent customer service despite the chaos at George Bush airport in Houston!

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Once we got in the air the pilot made up some of the time of the delay. So that was really nice.

We boarded but then sat there waiting on some missed connection people to get on so we sat for about 15 minutes for that. Then we sat again because the passenger manifest was wrong and they had to figure it out before we could leave. That took about another 20 minutes or so. The crew was working hard to figure it out so it’s not their fault. It ended up being a system glitch where someone was upgraded to first class while another person was also in the same seat and it just created a mess that took a little while to figure out. They literally went to every person on the plane asking their names to see who was sitting in the wrong seat. I also hate the entertainment that must be watched on your phone or tablet. Just give us setback screens. It’s so much better. Almost every Delta flight has this now and it is so nice to have them. The crew did a great job. I have no complaints from them. They were very hard working, even with the mishap and a disgruntled passenger.

Had a short delay once we boarded the aircraft in Chicago, but it was fixed in no time flat then we were on our way. The pilot was able to make up the time lost and we landed 5 minute later then schedualed . Great service

For some strange reason I was put in zone 5 for boarding even though I had paid premium price for a premium seat right behind business class. This must have been a flaw because everyone else around me in the same zone (row) had been placed in zone 3.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Newport
Lenoir City
Dandridge
Clinton
Jefferson City

Everything you need to know for your flight to Knoxville

Information on the airport you'll fly into in Knoxville