$120 Find Cheap Flights from Mississippi to South Carolina - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheap Flights from Mississippi to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Charlotte
1h 44mNonstop
from $263per person
Greenville
2h 59m2 stops
from $265per person
Charleston
3h 10m2 stops
from $281per person
Savannah
3h 10m2 stops
from $297per person
Myrtle Beach
3h 27m2 stops
from $309per person
Hilton Head Island
4h 18m2 stops
from $339per person
Columbia
3h 12m2 stops
from $369per person
Augusta
4h 01m2 stops
from $377per person
Explore the map
Useful Info

Good to know

Low season

January

Cheapest flight

$120
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Gulfport to Charlotte

FAQs for booking flights from Mississippi to South Carolina

  • How does KAYAK find such low prices on flights from Mississippi to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mississippi to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mississippi to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Mississippi to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mississippi to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Mississippi to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mississippi to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Mississippi to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in South Carolina?

    There are 6 airports in South Carolina. The busiest airport is Charleston Municipal Airport (CHS), with 43% of all flights arriving there.

  • How long is the flight to South Carolina?

    An average nonstop flight from Mississippi to South Carolina takes 5h 11m, covering a distance of 574 miles. The shortest route is Memphis (MEM) to Charlotte (CLT) with an average flight time of 1h 49m.

  • What are the most popular destinations in South Carolina?

    Based on KAYAK flight searches, the most popular destination is Charleston (34% of total searches to South Carolina). The next most popular destinations are Savannah (25%) and Greenville (21%). Searches for flights to Myrtle Beach (18%) and to Florence (2%) are also popular.

Reviews of the top airlines flying from Mississippi to South Carolina

 
Need help choosing which airline to fly with from Mississippi to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4190 reviews
8.1Boarding
8.0Comfort
7.5Entertainment
7.0Food
8.6Crew
Airline reviews

Terrible delay today. also, waited 90 minutes for baggage to unload in Seattle earlier in the week.

4.0 OkayHervey, Sep 2026
Read more Southwest reviews

Terrible delay today. also, waited 90 minutes for baggage to unload in Seattle earlier in the week.

Like new plane. Great crew. Comfortable. Clean. On time. Happy employees. Good organization and control of passengers.

Flights delays were communicated timely and helpfully, but there was a significant delay without any real effort to make up for that. Also, the in-flight WiFi was very spotty. That said, this was my first time with Southwest and I was quite happy with the service and staff otherwise.

Delayed and once landed waited very long for the luggage

Nice managed … it was a smaller plane, so the seating wasn’t as comfortable.

The Southwest airline was ok. A big thank you to Kayak team (David), who worked with me on Sunday afternoon to rebook my travel from Burbank, CA, to CVG. My original flight on Sunday was delayed, so I had to cancel Sunday flight and rebook my travel to Monday. Could not have done it without help from David from Kayak team. Ante Soda GE Aerospace

Seated at front bulkhead for a smidge extra leg room away from home and on flight back home. Away crew was very proactive about assuring our carryons had space close behind us (because no seat in front of us our personal items had to be in a small bin overhead). They actively required passengers place overhead luggage on its side so more items could fit in bins. Home crew made no such efforts. I had to struggle back rows to get overhead bags upon landing, no crew help then either, and some disgruntled passengers as I and others retrieved our bags. There was a system that worked pretty well. The home bound crew just didn't feel like working.

Southwest has inacted unfriendly customer policies like other airlines. Watch the fine print very carefully if you are having to alter flight arrangements. Rules are now complicated and very stilted to travelers sacrificing travel funds (unlike before where the simple, straight forward flight change policy was worth the extra premium for ticket price.) On the positive side, SW Flight crews are still wonderfully helpful.

I'm glad it wasn't only 75% full because I could get a good seat

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was delayed at airport with large backlog and WiFi was spotty

I don’t like mushrooms and that’s all they had with pasta

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

More options for your flight to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental