$71 Find Cheap Flights from Myrtle Beach to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Florida Keys departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Florida Keys, as well as popular online travel agencies
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Cheap Flights from Myrtle Beach to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$161
Key West
Key West1 stop$225
Miami
Miami1 stop$161
Key West
Key West1 stop$225

Book Cheap Myrtle Beach to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Florida Keys

Fri, Oct 17 - Thu, Oct 23
Frontier Logo
3:49 pm - 6:22 pmMYR-MIA
26h 33m1 stop
Frontier Logo
1:00 pm - 2:54 pmMIA-MYR
25h 54m1 stop
$161Frontier
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Fri, Oct 17 - Fri, Oct 24
 Logo
3:49 pm - 6:22 pmMYR-MIA
26h 33m1 stop
 Logo
9:24 pm - 5:49 pmMIA-MYR
20h 25m2 stops
Thu, Oct 23 - Mon, Oct 27
American Airlines Logo
5:59 pm - 12:29 amMYR-MIA
6h 30m1 stop
American Airlines Logo
5:18 am - 10:36 amMIA-MYR
5h 18m1 stop
$209American Airlines
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Tue, Jan 13 - Sat, Jan 17
American Airlines Logo
9:09 am - 3:18 pmMYR-EYW
6h 09m1 stop
American Airlines Logo
8:10 am - 2:10 pmEYW-MYR
6h 00m1 stop
$225American Airlines
Find Deal
Fri, Oct 17 - Sun, Oct 19
Spirit Airlines Logo
6:47 am - 8:32 pmMYR-MIA
13h 45m1 stop
Spirit Airlines Logo
9:49 am - 11:56 pmMIA-MYR
14h 07m1 stop
$230Spirit Airlines
Find Deal
Wed, Nov 12 - Wed, Dec 3
Spirit Airlines Logo
9:59 am - 10:02 amMYR-MIA
24h 03m1 stop
Spirit Airlines Logo
6:00 am - 7:35 pmMIA-MYR
13h 35m2 stops
$250Spirit Airlines
Find Deal
Fri, Nov 7 - Sun, Nov 9
Delta Logo
2:35 pm - 8:06 pmMYR-EYW
5h 31m1 stop
Delta Logo
7:40 am - 1:56 pmEYW-MYR
6h 16m1 stop
$314Delta
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Tue, Mar 10 - Wed, Mar 11
Delta Logo
2:15 pm - 7:44 pmMYR-EYW
5h 29m1 stop
Delta Logo
6:00 pm - 11:35 pmEYW-MYR
5h 35m1 stop
$539Delta
Find Deal
Mon, Nov 10 - Sun, Nov 16
Breeze Airways Logo
2:14 pm - 11:05 amMYR-EYW
20h 51m1 stop
Breeze Airways Logo
8:55 am - 10:00 amEYW-MYR
49h 05m3 stops
$632Breeze Airways
Find Deal
Wed, Oct 8 - Mon, Oct 13
Breeze Airways Logo
2:40 pm - 8:15 amMYR-EYW
41h 35m2 stops
Breeze Airways Logo
11:11 am - 6:11 pmEYW-MYR
7h 00m2 stops
$663Breeze Airways
Find Deal
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Florida Keys flights

Get data-powered insights and trends into flights from Myrtle Beach to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Myrtle Beach to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $232, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Myrtle Beach to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Florida Keys is October, when tickets cost $246 (return) on average. On the other hand, the most expensive months are April and December, when the average cost of round-trip tickets is $422 and $409 respectively.

What’s the cheapest day of the week to fly from Myrtle Beach to Florida Keys?

The average price of all round-trip flights from Myrtle Beach to Florida Keys clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to Florida Keys, you should consider leaving on a Monday and avoid Fridays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Mondays and the most expensive ones on Tuesdays.

How far in advance should I book a flight from Myrtle Beach to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Myrtle Beach to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Myrtle Beach to Florida Keys, you should book around 3 weeks before departure, which saves you about 14% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 6 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$71
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Myrtle Beach to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Florida Keys?

    The cheapest time of day to fly to Florida Keys is generally in the afternoon, when round-trip flights cost $194 on average. Morning departures are around 26% cheaper than evening flights, on average. The most expensive time of day to fly to Florida Keys is generally in the evening, which is peak travel time and where the average cost of a ticket is $357.

Reviews of the top 3 airlines serving from Myrtle Beach to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7954 reviews
7.3Food
7.9Comfort
8.2Boarding
7.9Entertainment
8.5Crew
Airline reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

10.0 ExcellentAnonymous, Sep 2025CLT - BOS
Read more Delta reviews

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

this crew didn't care much. bumping carts into seats more times than i care to remember

Everything was fine except the entertainment was not working for half of the flight.

Easy boarding with an extremely kind attendant. Seats were spacious and we had 3 seats for 2 people so we could stretch out. Comfortable air flow and very attentive and hospital attendants. Bathrooms and food were the only negative. Bathrooms were so small you could hardly get in and close the door. I don’t think an obese person would fit or a person with a movement disability. Food was the trending food for flights, nonexistent. We spent $40 getting sandwich and snack at airport for our 6 hour flught.

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Waited on the runway for takeoff for 2.5 hours. Air traffic rerouted us. The plane didn't have enough fuel, so had to go back to the gate. Had to wait for a new pilot. Should have landed at 5:22. Didn't land until 9:10. Trash flight.

The boarding was pretty easy. However, the first class seats are not lay flat as other airlines (like JetBlue) has and therefore sleeping was a challenge.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

Would have thought that they would gas up plane before everyone got on board

Fine. On time, cabin service was fine, bag arrived. All good. Flying into DCA so did not collide with any helicopters, which is also good. Horrid incident that could have and should have been prevented.

Everything was fine. I'm average height and I pack light. I'm ready for my Spirit flight.

Wow truly top notch airline Efficient nice snacks courteous staff Fast boarding !

My experience with Spirit was good, but the experience with Kayak was not. Based on the Spirit agent Kayak added an additional charge after purchasing the tickets. When I buy the tickets I paid the total amount and I only pay once. This time they added an additional charge because based on Spirit they partially charge the tickets and I still needed to pay a second time. This is not good at all and Unprofessional

Spirit gets such a bad rap. I have never had a bad experience with them and the crew is always friendly and funny. This trip I had knee replacement surgery surgery 10 weeks ago. It is still a little rough to get get from point a to point b. And Spirit was on top of it. When there was a seat available the stewardess asked me if I wanted to move to an open seat so I could elevate my leg on the empty seat? 5 stars all around. They helped me on and helped me off the plane. I can’t say enough about the crew!!

This gate agents are always so rude! I stopped flirting with spirit years ago for that reason I thought it would change by now. It’s so tacky they try to treat you like a school child i hate it

The staff was very sarcastic, the flight was delayed. There was no wi-fi o any type of entertainment. The plane was dirty and we have to wait a long time for the luggage to come out.

Although our flight had delays due to three different reasons, it was good. Staff continued to update us which made every one comfortable. We felt the captain and crew had our safety in mind the entire time and no one seemed to lose their patience.

Booked through kayak, everything seemed normal but when it came time to go, my flight ticket didn’t exist, so I had to purchase another set of tickets at the airport the day of the flight, for about double. When I reached kayaks customer service, they claimed no responsibility, and pushed me onto another 3rd party booking service, airfare assist, where I have had no luck getting any kind of help or refund. I’ve used kayak many times, but I’ll never again after I’ve been burned by this.

The air fares are good, Charging me for every single thing 😩

I am very happy with my experience with Spirit Airlines. Both flights were on time. Boarding was very pleasant. Crew was very nice. Flights were amazing and we even arrived earlier than the schedule time. I am hoping Spirits keeps on having non stop flight from Ft Lauderdale to Hartford for many years to come.

Everything you need to know for your flight to Florida Keys

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