$93 Find Cheap Flights from Myrtle Beach to Florida Keys

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Florida Keys departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Florida Keys

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Florida Keys, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Florida Keys, as well as popular online travel agencies
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Cheap Flights from Myrtle Beach to Florida Keys

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Miami
Miami1 stop$178
Key West
Key West1 stop$254
Miami
Miami1 stop$178
Key West
Key West1 stop$254

Book Cheap Myrtle Beach to Florida Keys Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Florida Keys that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Florida Keys

Tue, May 5 - Tue, May 12
Spirit Airlines Logo
8:31 pm - 1:04 pm
MYR
-
MIA
16h 33m
1 stop
Spirit Airlines Logo
4:05 pm - 8:44 am
MIA
-
MYR
16h 39m
1 stop
$178Spirit Airlines
Mon, May 4 - Sat, May 9
Frontier Logo
5:29 pm - 8:14 pm
MYR
-
MIA
26h 45m
1 stop
Frontier Logo
9:19 pm - 2:46 pm
MIA
-
MYR
17h 27m
1 stop
$191Frontier
Sat, Apr 25 - Fri, May 1
Spirit Airlines Logo
8:31 pm - 1:04 pm
MYR
-
MIA
16h 33m
1 stop
Spirit Airlines Logo
4:05 pm - 8:44 am
MIA
-
MYR
16h 39m
1 stop
$194Spirit Airlines
Tue, Apr 14 - Tue, Apr 21
Spirit Airlines Logo
9:49 pm - 1:04 pm
MYR
-
MIA
15h 15m
1 stop
Spirit Airlines Logo
4:05 pm - 8:44 am
MIA
-
MYR
16h 39m
1 stop
$198Spirit Airlines
Sat, May 2 - Fri, May 8
Spirit Airlines Logo
8:31 pm - 1:04 pm
MYR
-
MIA
16h 33m
1 stop
Spirit Airlines Logo
4:05 pm - 8:44 am
MIA
-
MYR
16h 39m
1 stop
$202Spirit Airlines
Wed, May 6 - Mon, May 11
Spirit Airlines Logo
8:31 pm - 1:04 pm
MYR
-
MIA
16h 33m
1 stop
Spirit Airlines Logo
7:09 pm - 3:10 pm
MIA
-
MYR
20h 01m
1 stop
$207Spirit Airlines
Tue, May 5 - Tue, May 19
Multiple Airlines Logo
8:31 pm - 1:04 pm
MYR
-
MIA
16h 33m
1 stop
Multiple Airlines Logo
6:30 am - 7:37 pm
MIA
-
MYR
37h 07m
2 stops
$220Multiple Airlines
Sun, Mar 29 - Thu, Apr 2
Breeze Airways Logo
5:53 pm - 9:09 am
MYR
-
EYW
15h 16m
1 stop
Breeze Airways Logo
9:46 am - 2:22 pm
EYW
-
MYR
4h 36m
1 stop
$254Breeze Airways
Sun, May 3 - Thu, May 7
Breeze Airways Logo
6:59 pm - 9:09 am
MYR
-
EYW
14h 10m
1 stop
Breeze Airways Logo
11:04 am - 11:39 am
EYW
-
MYR
24h 35m
1 stop
$265Breeze Airways
Wed, Apr 15 - Wed, Apr 22
Delta Logo
1:43 pm - 7:40 pm
MYR
-
EYW
5h 57m
1 stop
Delta Logo
6:23 pm - 12:14 am
EYW
-
MYR
5h 51m
1 stop
$291Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Florida Keys flights

Get data-powered insights and trends into flights from Myrtle Beach to Florida Keys to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Myrtle Beach to Florida Keys?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $273, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Myrtle Beach to Florida Keys?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Florida Keys is October, when tickets cost $291 (return) on average. On the other hand, the most expensive months are February and March, when the average cost of round-trip tickets is $432 and $418 respectively.

How far in advance should I book a flight from Myrtle Beach to Florida Keys?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Myrtle Beach to Florida Keys, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Myrtle Beach to Florida Keys, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$93
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Myrtle Beach to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Florida Keys is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Florida Keys with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Florida Keys up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to Florida Keys

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8288 reviews
7.9Comfort
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
Airline reviews

The whole experience was excellent. As it most often is with Delta

10.0 ExcellentRay, Mar 2026
LGA - MCO
Read more Delta reviews

The whole experience was excellent. As it most often is with Delta

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

Plane from partner PSA was filthy. Plastic needs to be thoroughly cleaned. Really disgusting to look at and wonder about cleanliness of parts less visible.

Flight delay for mechanical. Inbound arrived on time. No one said why mechanical delay.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Horrendous and unprofessional staff and will never fly spirit again

Sadly the flight was delayed by 4 hours due to the weather snd sir traffic control staffing. Otherwise the crew was amazing and the flight was perfect.

The plane was clean and crew was nice. Can’t speak on food as I did not have any

We get stuck in the plane when landed during 45min and no communication from the crew People were listening to their phone and music out loud and nobody told them anything I definitely want stop booking spirit flight it is a disaster

Good: It was cheap and they got us to our destination safely. Not so Good: Gates experience with many, many nauseatingly (almost) threatening announcements about bags size and how much they were going to charge us if our bag was too big, even to the point of having a gate agent roaming around through the passengers eyeballing bags size and making people go check their bags in the sizers.

Everything is an additional fee. No one said anything when I checking in and got my boarding pass about my small carry on suitcase. Charged me $100 at the gate for that little bag that I still had to take with me. Delays for both flights for no reason and then when I asked everyone said something different. Never flying spirit again. If it was just one thing maybe. This was a show from the minute I got to the airport.

Terrible. The flight was randomly delayed in Chicago causing us to miss our connection and they offered us a flight the next day at 6 am and it would have taken till 345 to get to Pensacola. They didn’t cover any fees. Our bags also supposedly were on the flight to Pensacola and we tried to get them yesterday after driving 6 hours and nobody was available. Worst company ever and will never use them again. Had to pay for a rental. Spirit is claiming in climate weather for the delay but there wasn’t any weather issuesz it’s a bunch of bullshit and I am not happy

Checking in at desk in Chicago was horrible. Person was not friendly never smiled and said my flight was not paid for so I had to give another credit card. Then it ended up that I was charged twice. Then after arriving at my destination had to wait on the phone a long time to speak to a person to fix the double charge! Thank goodness the flight was perfect.

The bag situation was confusing. I didn’t know I had to pay for Carry ons. The seats were uncomfortable and there was no entertainment

It was terrible. I had to pay again once I got to the airport because they said they never received the payment.

Everything you need to know for your flight to Florida Keys

Information on your arrival and departure airports