$440 Find Cheap Flights from Myrtle Beach to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Flight Deals

Book Cheap Myrtle Beach to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama

Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:37 pm - 2:20 pmMYR-PTY
20h 43m2 stops
American Airlines Logo
1:50 pm - 12:11 pmPTY-MYR
21h 21m2 stops
$440American Airlines
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Tue, Dec 2 - Tue, Dec 9
American Airlines Logo
7:41 pm - 1:47 pmMYR-PTY
18h 06m2 stops
American Airlines Logo
4:43 pm - 11:39 amPTY-MYR
18h 56m2 stops
$460American Airlines
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Tue, Dec 2 - Thu, Dec 4
American Airlines Logo
7:41 pm - 1:47 pmMYR-PTY
18h 06m2 stops
American Airlines Logo
2:50 pm - 10:04 amPTY-MYR
19h 14m2 stops
$480American Airlines
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Mon, Nov 24 - Wed, Nov 26
Delta Logo
6:50 pm - 2:12 pmMYR-PTY
19h 22m1 stop
Delta Logo
3:37 pm - 9:26 amPTY-MYR
17h 49m1 stop
$490Delta
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Fri, Dec 5 - Sun, Dec 7
Delta Logo
10:32 am - 7:59 pmMYR-PTY
9h 27m1 stop
Delta Logo
3:46 pm - 11:43 pmPTY-MYR
7h 57m1 stop
$516Delta
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Thu, Dec 4 - Sun, Dec 7
Delta Logo
6:56 pm - 7:59 pmMYR-PTY
25h 03m1 stop
Delta Logo
3:46 pm - 11:43 pmPTY-MYR
7h 57m1 stop
$523Delta
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Tue, Dec 2 - Wed, Dec 3
Multiple Airlines Logo
6:15 am - 1:00 amMYR-PTY
18h 45m2 stops
Multiple Airlines Logo
2:55 am - 5:48 pmPTY-MYR
14h 53m2 stops
$524Multiple Airlines
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Mon, Nov 24 - Thu, Nov 27
American Airlines Logo
1:54 pm - 1:43 pmMYR-PTY
23h 49m2 stops
American Airlines Logo
2:43 pm - 11:55 amPTY-MYR
21h 12m2 stops
$530American Airlines
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Tue, Dec 2 - Mon, Dec 8
Multiple Airlines Logo
6:15 am - 1:00 amMYR-PTY
18h 45m2 stops
Multiple Airlines Logo
2:55 am - 5:48 pmPTY-MYR
14h 53m2 stops
$564Multiple Airlines
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Mon, Dec 1 - Wed, Dec 3
American Airlines Logo
8:07 pm - 1:43 pmMYR-PTY
17h 36m2 stops
American Airlines Logo
4:43 pm - 10:42 amPTY-MYR
17h 59m2 stops
$590American Airlines
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Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Panama?

The average price of all round-trip flights from Myrtle Beach to Panama clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Thursday is the most expensive day to fly from Myrtle Beach to Panama. For your return ticket, we recommend flying on a Monday and avoiding Wednesdays for the best deals.

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Good to know

Cheapest flight$440
Flight from Myrtle Beach to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $572 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $572.

Reviews of the top airline flying from Myrtle Beach to Panama

 
Need help choosing which airline to fly with from Myrtle Beach to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11026 reviews
8.0Crew
7.2Comfort
6.9Entertainment
7.5Boarding
6.4Food
Airline reviews

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

8.0 ExcellentChristina, Oct 2025BTV - CLT
Read more American Airlines reviews

Typically flights with AA are good. The staff are pleasant, welcoming, and efficient.

A couple ladies from the crew were so rude and nasty. Thought they were mad at having to be there especially if you asked a question. This will make me think twice next time if I book a flight with you.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was a typical flight. We had a delay which seems to be the normality now. And we had no in flight service due to conditions.

Flight attendants on this flight were very attentive and friendly

After we landed we sat on the tarmac for 1.5 hours waiting to get to our gate. Ridiculous.

Everything you need to know for your flight from Myrtle Beach to Panama

Information on your arrival and departure airports

Myrtle Beach (MYR)

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