$205 Find Cheap Flights from Myrtle Beach to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Myrtle Beach to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama

Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:35 pm - 2:22 pmMYR-PTY
20h 47m2 stops
American Airlines Logo
1:44 pm - 10:01 amPTY-MYR
19h 17m2 stops
$480American Airlines
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Thu, Jan 15 - Mon, Feb 16
Multiple Airlines Logo
9:59 pm - 6:55 pmMYR-PTY
20h 56m2 stops
Multiple Airlines Logo
11:25 am - 2:34 pmPTY-MYR
27h 09m3 stops
$777Multiple Airlines
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Thu, Jan 15 - Mon, Feb 16
Multiple Airlines Logo
8:15 pm - 8:19 pmMYR-PTY
24h 04m1 stop
Multiple Airlines Logo
7:50 pm - 8:15 amPTY-MYR
36h 25m2 stops
$788Multiple Airlines
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Thu, Mar 19 - Thu, Mar 26
Delta Logo
6:00 am - 12:55 pmMYR-PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:59 pmPTY-MYR
8h 39m1 stop
$794Delta
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Thu, Jan 15 - Sun, Feb 15
Multiple Airlines Logo
9:59 pm - 6:55 pmMYR-PTY
20h 56m2 stops
Multiple Airlines Logo
2:55 am - 8:15 amPTY-MYR
29h 20m3 stops
$801Multiple Airlines
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Thu, Jan 15 - Mon, Feb 16
Multiple Airlines Logo
10:00 am - 2:00 pmMYR-PTY
28h 00m3 stops
Multiple Airlines Logo
11:25 am - 2:34 pmPTY-MYR
27h 09m3 stops
$803Multiple Airlines
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Thu, Jan 15 - Sun, Feb 15
Multiple Airlines Logo
10:00 am - 2:00 pmMYR-PTY
28h 00m3 stops
Multiple Airlines Logo
2:55 am - 8:15 amPTY-MYR
29h 20m3 stops
$827Multiple Airlines
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Thu, Jan 15 - Sun, Feb 15
Multiple Airlines Logo
8:15 pm - 8:19 pmMYR-PTY
24h 04m1 stop
Multiple Airlines Logo
2:55 am - 11:57 pmPTY-MYR
21h 02m2 stops
$863Multiple Airlines
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Thu, Jan 15 - Sun, Feb 15
Multiple Airlines Logo
9:59 pm - 6:55 pmMYR-PTY
20h 56m2 stops
Multiple Airlines Logo
2:55 am - 11:57 pmPTY-MYR
21h 02m2 stops
$875Multiple Airlines
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Fri, Dec 26 - Fri, Jan 2
Delta Logo
6:00 am - 8:00 pmMYR-PTY
14h 00m1 stop
Delta Logo
8:00 am - 8:29 pmPTY-MYR
12h 29m1 stop
$1,110Delta
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Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Panama?

The average price of all round-trip flights from Myrtle Beach to Panama clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Thursday is the most expensive day to fly from Myrtle Beach to Panama. For your return ticket, we recommend flying on a Monday and avoiding Wednesdays for the best deals.

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Good to know

Cheapest flight$205
Flight from Myrtle Beach to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $572 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $572.

Reviews of the top airline flying from Myrtle Beach to Panama

 
Need help choosing which airline to fly with from Myrtle Beach to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11042 reviews
6.4Food
8.0Crew
6.9Entertainment
7.5Boarding
7.2Comfort
Airline reviews

I like that the crew kept us informed but we moved back and forth from gate to gate before the aircraft arrived.

8.0 ExcellentWayne, Nov 2025MIA - BWI
Read more American Airlines reviews

I like that the crew kept us informed but we moved back and forth from gate to gate before the aircraft arrived.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Everything you need to know for your flight from Myrtle Beach to Panama

Information on your arrival and departure airports

Myrtle Beach (MYR)