$130 Find Cheap Flights from Myrtle Beach to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$371
San José
San José1 stop$309
Guatemala City
Guatemala City1 stop$360
Panama City
Panama City2 stops$440
Coxen Hole
Coxen Hole2 stops$624
San Salvador
San Salvador1 stop$371
San José
San José1 stop$309
Guatemala City
Guatemala City1 stop$360
Panama City
Panama City2 stops$440
Coxen Hole
Coxen Hole2 stops$624

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Sun, Feb 8 - Sat, Feb 14
Spirit Airlines Logo
8:15 pm - 12:22 pm
MYR
-
SJO
17h 07m1 stop
Spirit Airlines Logo
1:31 pm - 8:13 am
SJO
-
MYR
17h 42m1 stop
$309Spirit Airlines
Sun, Feb 8 - Sat, Feb 14
Spirit Airlines Logo
8:15 pm - 11:37 am
MYR
-
SJO
16h 22m2 stops
Spirit Airlines Logo
1:31 pm - 8:13 am
SJO
-
MYR
17h 42m1 stop
$312Spirit Airlines
Sun, Feb 8 - Sat, Feb 14
Spirit Airlines Logo
8:15 pm - 11:37 am
MYR
-
SJO
16h 22m2 stops
Spirit Airlines Logo
12:35 pm - 8:13 am
SJO
-
MYR
18h 38m2 stops
$325Spirit Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:23 pm - 2:22 pm
MYR
-
PTY
20h 59m2 stops
American Airlines Logo
1:44 pm - 8:31 am
PTY
-
MYR
17h 47m2 stops
$440American Airlines
Wed, Feb 4 - Wed, Mar 4
American Airlines Logo
5:44 pm - 3:38 pm
MYR
-
PTY
21h 54m2 stops
American Airlines Logo
2:50 pm - 11:49 am
PTY
-
MYR
20h 59m2 stops
$460American Airlines
Tue, Feb 3 - Tue, Mar 3
American Airlines Logo
5:44 pm - 1:27 pm
MYR
-
PTY
19h 43m2 stops
American Airlines Logo
2:50 pm - 10:44 am
PTY
-
MYR
19h 54m2 stops
$480American Airlines
Thu, Feb 26 - Tue, Mar 3
American Airlines Logo
7:56 pm - 11:47 am
MYR
-
BZE
16h 51m1 stop
American Airlines Logo
4:40 pm - 5:03 pm
BZE
-
MYR
23h 23m2 stops
$489American Airlines
Sun, Feb 1 - Wed, Mar 4
Delta Logo
6:54 pm - 1:55 pm
MYR
-
PTY
19h 01m1 stop
Delta Logo
3:15 pm - 9:45 am
PTY
-
MYR
18h 30m1 stop
$490Delta
Sun, Jan 18 - Thu, Feb 12
Delta Logo
10:33 am - 1:55 pm
MYR
-
PTY
27h 22m1 stop
Delta Logo
3:15 pm - 9:45 am
PTY
-
MYR
18h 30m1 stop
$510Delta
Sun, Jan 18 - Fri, Feb 13
Delta Logo
4:00 pm - 1:55 pm
MYR
-
PTY
21h 55m1 stop
Delta Logo
3:15 pm - 9:40 am
PTY
-
MYR
18h 25m1 stop
$530Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Myrtle Beach and Central America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Myrtle Beach to Central America.

There are 3 airlines that fly nonstop from Myrtle Beach to Central America. They are: American Airlines, Delta and Spirit Airlines. The cheapest price of all airlines flying this route was found with Spirit Airlines at $267 for a round-trip flight to San José (SJO). On average, Spirit Airlines offers the best prices for nonstop flights between Myrtle Beach and Central America.

Which airlines provide the cheapest flights from Myrtle Beach to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Central America were found on Spirit Airlines ($309) and American Airlines ($440).

Good to know

Low seasonAugust
Cheapest flight$130
Best time to beat the crowds with an average 27% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Myrtle Beach to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Central America?

    The cheapest time of day to fly to Central America is generally in the morning, when round-trip flights cost $724 on average. The most expensive time of day to fly to Central America is generally in the morning, which is peak travel time and where the average cost of a ticket is $724.

Reviews of the top 3 airlines serving from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8014 reviews
8.5Crew
7.3Food
7.9Comfort
8.1Boarding
7.9Entertainment
Airline reviews

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

2.0 MediocrePeter, Dec 2025
JFK - MEM
Read more Delta reviews

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Wasn't a Delta issue I don't think, but seems there was a Delta flight at each of the 2 Dallas airports at the same exact time, both to Atlanta. I was evidently booked on the one at Love Airport, but the Carey transport shuttle took me to DFW instead and I ended up missing the flight by just a few minutes. Was able to book a Southwest flight from Love Airport, but was a big loss of time and an inconvenience.

Great. I had to modify a flight. That was easy and free. Thank You

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

I don’t know who decides what food to serve on these flights but I would be so embarrassed if I served this to anyone and call it food…

For whatever reason, the flight was not catered -we were told it would be a 45 minute delay waiting for catering - so no food. There were opened candy and peanuts in the seatback pocket. Flight landed early in DFW but due to the assigned gate not being available, we sat on the ground for 30 minutes waiting for the gate to open - making the flight actually arrive at the gate late.

Not great. Booked Extra seats and got nothing extra at all. It’s basically a big budget airline.

The pilot greased the landing and the crew was fantastic.

I bought wifi and most of the flight could not even use it my apps would just spin. I couldn't even listen to music. super frustrating.

delayed due to weather. Could not communicate with family since the wifi was broken

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Flight was delayed 17 hours due to aircraft issues. American did provide hotel, transportation and meals, 3 hours past boarding time, but it took us another hour to get the vouchers.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

Spirit cancelled the flight very late last night, I was on the way to the airport when I found out

First time in a decade I threw up on the flight, turbulence was terrible!! The staff were kinda rude at times.

Boarding was good, clearly explained and efficient. Staff were helpful, I would've liked a place to get coffee that wasn't Starbucks

The most horrible flight ever not only Spirit delayed our flight 2 hours departure time for a 1 hour flight — that I could have driven FLL to TPA and spend less time on the road —- and they did the same on the return with 2-hr delay again!!! Then to top all, the rubber like and most unconfortable seats in the industry with no leg room!!! There should be an award for these kinds of companies measuring % of returning customers!!!

The flight was cancelled and Spirit said they could not rebook me on another flight for six days. They said they couldn't do anything for another six days.

Flight was on time, Newark staff, especially Nathan, very helpful, and plane crew to RDU very good without being pushy. We arrived early, and had a gentle landing.

See my last comment for the first leg. That should’ve been in here

Horrible. Arrived at my gate at 6:37 for a 6:50 flight and was denied by staff to board. Literally watched my flight leave from the window and it didn’t take off until after 7am. Tried to talk to staff and they were rude beyond compare. Will never fly with this airline again.

Our flight got rescheduled 48 hours later, the airline didn’t pay a penny for our expenses.

We had to sit and wait for almost an hour after landing and taxiing to the gate. The jet bridge was broken so we just waited and waited and waited and it was inconvenient, hot, and unnecessary.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports