$145 Find Cheap Flights from Myrtle Beach to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$290
San José
San José1 stop$308
Guatemala City
Guatemala City1 stop$268
Panama City
Panama City2 stops$436
Managua
Managua2 stops$533
Coxen Hole
Coxen Hole2 stops$652
San Salvador
San Salvador1 stop$290
San José
San José1 stop$308
Guatemala City
Guatemala City1 stop$268
Panama City
Panama City2 stops$436
Managua
Managua2 stops$533
Coxen Hole
Coxen Hole2 stops$652

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Wed, Mar 11 - Tue, Mar 17
Spirit Airlines Logo
9:09 am - 11:34 am
MYR
-
GUA
28h 25m
1 stop
Spirit Airlines Logo
12:59 am - 5:39 pm
GUA
-
MYR
14h 40m
1 stop
$268Spirit Airlines
Wed, Mar 11 - Tue, Mar 17
Spirit Airlines Logo
3:59 pm - 11:34 am
MYR
-
GUA
21h 35m
2 stops
Spirit Airlines Logo
12:59 am - 5:39 pm
GUA
-
MYR
14h 40m
1 stop
$285Spirit Airlines
Fri, Feb 27 - Sat, Mar 7
Spirit Airlines Logo
9:09 am - 12:22 pm
MYR
-
SJO
28h 13m
1 stop
Spirit Airlines Logo
1:31 pm - 7:13 am
SJO
-
MYR
16h 42m
1 stop
$308Spirit Airlines
Fri, Feb 27 - Sat, Mar 7
Spirit Airlines Logo
9:09 am - 11:40 am
MYR
-
SJO
27h 31m
2 stops
Spirit Airlines Logo
1:31 pm - 7:13 am
SJO
-
MYR
16h 42m
1 stop
$311Spirit Airlines
Mon, Mar 16 - Fri, Mar 20
Multiple Airlines Logo
6:37 pm - 3:06 pm
MYR
-
SJO
22h 29m
2 stops
Multiple Airlines Logo
4:17 pm - 2:32 pm
SJO
-
MYR
20h 15m
2 stops
$400Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Multiple Airlines Logo
9:54 pm - 10:20 am
MYR
-
GUA
38h 26m
2 stops
Multiple Airlines Logo
12:33 pm - 5:39 pm
GUA
-
MYR
27h 06m
1 stop
$412Multiple Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
6:22 pm - 12:40 pm
MYR
-
PTY
19h 18m
2 stops
American Airlines Logo
1:49 pm - 9:58 am
PTY
-
MYR
19h 09m
2 stops
$461American Airlines
Sun, May 10 - Wed, May 13
Delta Logo
6:00 am - 11:14 am
MYR
-
BZE
7h 14m
1 stop
Delta Logo
12:35 pm - 11:38 pm
BZE
-
MYR
9h 03m
1 stop
$461Delta
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
5:19 pm - 12:40 pm
MYR
-
PTY
20h 21m
2 stops
American Airlines Logo
1:40 pm - 8:32 am
PTY
-
MYR
17h 52m
2 stops
$481American Airlines
Fri, May 8 - Wed, May 13
Delta Logo
6:00 am - 11:14 am
MYR
-
BZE
7h 14m
1 stop
Delta Logo
12:35 pm - 11:38 pm
BZE
-
MYR
9h 03m
1 stop
$486Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Central America were found on Spirit Airlines ($268) and American Airlines ($481).

Good to know

Low seasonAugust
Cheapest flight$170
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Myrtle Beach to Panama City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8112 reviews
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

2.0 MediocreAndrea, Jan 2026
CMH - MSP
Read more Delta reviews

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

My flight out of Baton Rouge to Atlanta was delayed by a half hour. This got us into Atlanta airport 30 minutes late. I ran through the airport to get to my connecting flight. As I approached the boarding gate, I saw the boarding door was still open and a passenger was being checked in. But when I got to the gate, the boarding agent told me they had already given away my seat and there were no empty seats on that flight. So I had to take a later flight. That has never happened to me before. Very frustrating.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

There was no wifi available on this flight. And there were no screens, no onboard entertainment, no entertainment options at all. It was like travelling in the 1990s again, except without even a main screen for options. Seats, as usual, were tight and uncomfortable.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

Because I was moved to an exit row, the snacks in economy comfort, the selection of snacks was better.

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

one crew said "he" didn't serve double alcohol drinks for travelers in exit rows. crew on prior flight did. Is this a AA rule, and the prior crew was being nice? Also, I think we deserve more than a 25% refund for losing first class seats when rescheduling a flight due to weather

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

2 hour delay due to equipment failure. No updates via the app and airport screens (which continued to show a departure time in the past). AA eventually switched planes and the new plane was not catered or cleaned correctly.

I booked an aisle seat and was given a middle. At 6'4" 230lbs, it is not ideal to fly in the middle row for myself and passengers.

Trip delayed for 2 hours because of rain. We boarded and have to get down the flight and reboard again.

The aircraft had several problems - from excess fuel to non operational ac. Two hours of delay in Chicago could have been avoided with proper planning and aircraft maintenance.

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Could we please end the loud announcements about credit card offers on your flights? We are trying to sleep, work, watch videos, etc. and if we need a credit card, we will ask for one. Flying is already not what it used to be.

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

This was my best experience with spirit. I flew you guys 4 times and I must say this was the BEST

Horribly late because they had no crew!!! And then jet bridge didn’t work!! Then we arrived at a gate at lax miles away that we had to take a shuttle to a terminal!! I was over 3 hours late to getting the LA! Should have been here at 8:30 and at an appointment at 10:30 and arrived and left lax at 11 am!! Horrible experience!!!

Extra legroom with my upgrade bundle. Clean aircraft, on-time departure, early arrival. Good value for the price.

I didn't have a flight because of a ticking problem that was discovered at the airport at checkin for the initial flight of the round trip.

Even though the plane was delayed from the previous airport, the staff recognized this and kept us informed. The flight crew was absolutely awesome from on my flight from Ft. Meyers to AC. Great experience all around!

Flight was delayed would have liked it to have been on time. I didn't experience the food or entertainment but the boarding process was smooth and the flight crew worked well together and did a great job!

Not seat assigned because overbooking. We could go because some people decided to give their seats.

Spirit loves to pick and choose when to harass you about your personal item. I’ve flown numerous times with the same bag with no problem yet flying out of Orlando they forced me to pay $99 for a carry on and then ran out of overhead space. Do better!

For the price of the fare, there really isn’t much to complain about.

didn't order food on board. there's no way to hold a water botton on the way. otherwise it was a pleasant flight, thanks to the crew.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports