$251 Find Cheap Flights from Myrtle Beach to Central America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$585
San José
San José1 stop$670
Guatemala City
Guatemala City1 stop$649
Panama City
Panama City1 stop$626
Managua
Managua2 stops$606
Coxen Hole
Coxen Hole2 stops$632
San Salvador
San Salvador2 stops$585
San José
San José1 stop$670
Guatemala City
Guatemala City1 stop$649
Panama City
Panama City1 stop$626
Managua
Managua2 stops$606
Coxen Hole
Coxen Hole2 stops$632

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Thu, Sep 3 - Wed, Sep 9
American Airlines Logo
7:33 pm - 11:21 am
MYR
-
MGA
17h 48m
2 stops
American Airlines Logo
12:23 pm - 11:37 am
MGA
-
MYR
21h 14m
2 stops
$606American Airlines
Mon, Aug 24 - Mon, Aug 31
United Airlines Logo
7:49 pm - 4:04 am
MYR
-
PTY
9h 15m
1 stop
United Airlines Logo
3:30 pm - 2:53 pm
PTY
-
MYR
22h 23m
2 stops
$626United Airlines
Wed, Jan 6 - Sat, Feb 6
American Airlines Logo
7:19 pm - 1:50 pm
MYR
-
RTB
19h 31m
2 stops
American Airlines Logo
2:42 pm - 9:43 am
RTB
-
MYR
18h 01m
2 stops
$632American Airlines
Wed, Jul 29 - Wed, Aug 5
Multiple Airlines Logo
2:42 pm - 1:42 pm
MYR
-
GUA
25h 00m
1 stop
Multiple Airlines Logo
2:47 pm - 8:55 am
GUA
-
MYR
16h 08m
1 stop
$649Multiple Airlines
Fri, Aug 14 - Mon, Aug 17
Multiple Airlines Logo
1:13 pm - 3:11 pm
MYR
-
SJO
27h 58m
1 stop
Multiple Airlines Logo
2:20 am - 9:05 am
SJO
-
MYR
28h 45m
2 stops
$670Multiple Airlines
Wed, Jul 29 - Fri, Aug 7
American Airlines Logo
6:45 pm - 12:14 pm
MYR
-
PTY
18h 29m
2 stops
American Airlines Logo
1:39 pm - 11:25 am
PTY
-
MYR
20h 46m
2 stops
$671American Airlines
Tue, Aug 11 - Mon, Aug 17
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m
1 stop
Delta Logo
2:20 pm - 11:30 pm
PTY
-
MYR
8h 10m
1 stop
$680Delta
Wed, Jul 29 - Fri, Aug 7
Delta Logo
6:00 am - 1:05 pm
MYR
-
PTY
8h 05m
1 stop
Delta Logo
2:20 pm - 11:30 pm
PTY
-
MYR
8h 10m
1 stop
$717Delta
Mon, Dec 21 - Mon, Dec 28
GOL Logo
2:34 pm - 10:35 am
MYR
-
GUA
21h 01m
2 stops
GOL Logo
11:41 am - 9:20 am
GUA
-
MYR
20h 39m
2 stops
$805GOL
Wed, Jul 29 - Wed, Aug 5
GOL Logo
6:51 am - 7:35 pm
MYR
-
GUA
14h 44m
2 stops
GOL Logo
2:23 pm - 11:34 am
GUA
-
MYR
19h 11m
2 stops
$840GOL
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Central America is May, when tickets cost $0 (return) on average. On the other hand, the most expensive months are June and March, when the average cost of round-trip tickets is $636 and $559 respectively.

Good to know

Low season

August

Cheapest flight

$251
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Myrtle Beach to San José

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8469 reviews
8.1Boarding
7.8Comfort
7.8Entertainment
8.5Crew
7.2Food
Airline reviews

I missed the flight because the Minneapolis flight was 49 minutes LATE, and the Boise flight LEFT 24 minutes EARLY!

2.0 MediocreAnonymous, Jul 2026
MSP - BOI
Read more Delta reviews

I missed the flight because the Minneapolis flight was 49 minutes LATE, and the Boise flight LEFT 24 minutes EARLY!

Our flight was delayed multiple times and then canceled at almost 1 in the morning. We are a family of 7, traveling with 5 young children. When the flight we were supposed to fly on finally arrived after waiting all day after an international flight into JFK we were informed our flight was in need of a copilot and once they located one we would take off. Then our flight was cancelled because the copilot was over his hours and they couldn't locate another. They knew before taking off from the previous location that the copilot would be unable to fly. They could have communicated the cancellation of the flight hours in advance. Once they cancelled and the pilot and copilot got off the flight, they joked about it. While there are understandably limits on flight time for pilots, they can still handle the situation in a professional manner. The late cancellation resulted in angry passengers that required police intervention in the airport. It also occurred so late and included other delta flights that after trying 15 different hotels, we were unable to secure a hotel room, they were all booked. No rental cars were available in the area either. We ended up staying in the airport with the 5 children. We made it home after 54 hours of travel with maybe 2 hours of sleep. Our luggage was lost and had to be claimed at the airport at our final destination. This was the worst trip I have ever taken and the worst airport I have ever spent time in. I met two individuals in the airport that were kind and helpful; Tonya Maingot Williams from the can we hel desk that worked to help get us rebooked and home, as well as provide us with care bags for our extended stay in the airport. The other individual was Danielle from Buffalo Wild Wings that was so very kind when we found a place to take our family we were traveling with to eat, all 11 of us and we were able to sit down together to enjoy a meal during such a stressful time.

My flight home from Knoxville, TN, included a layover in Atlanta. I boarded the aircraft in Zone 5 and although there was limited overhead space, I was able to put my 'backpack' style roller-bag above my seat. Unfortunately, due to continued bad weather, we had to deplane. There were many people who would have missed their connection, so they rebooked. When we were re-boarding, the gate agent welcomed zone 5 and then made an announcement: All roller-bags for zone 5 passengers and higher will need to be gate checked. I promptly pushed the telescoping handle in and held my bag like a backpack. I was able to bring it on board, which was a relief. Upon entering the aircraft it became apparent that there was easily 40% open overhead space. There were audible signs of angry passengers who felt duped into checking their bags when in fact there were noticeably LESS passengers on the aircraft and TONS of overhead space. I'm not sure what kinds of parameters are used to determine when to cut off roller-bags from being brought on board, but it seemed deceptive and underhanded to have so many people get stuck checking their bags when clearly there was ample room for at least one more zone.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

Very good I can’t complain one bit. Thank you American Airlines for making my flight enjoyable and safe!

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

Would have thought that they would gas up plane before everyone got on board

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

When my flight was delayed due to weather, I was rebooked to another flight since it showed that I would miss my connection. It was a lot of work to get back onto my originally connecting flight which was also delayed. That part caused a lot of stress and frustration. The ticketing agent at the desk was not very helpful.

American switched my flight to a 5 hour layover then cancelled my whole reservation with no notice and refused refund. Won’t fly with them again.

Flight was delayed 5 hours causing me to miss my connecting flights

Everything you need to know for your flight to Central America

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