$245 Find Cheap Flights from Myrtle Beach to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 7/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$453
San José
San José1 stop$535
Guatemala City
Guatemala City1 stop$349
Panama City
Panama City1 stop$506
Managua
Managua2 stops$698
Coxen Hole
Coxen Hole2 stops$572
San Salvador
San Salvador2 stops$453
San José
San José1 stop$535
Guatemala City
Guatemala City1 stop$349
Panama City
Panama City1 stop$506
Managua
Managua2 stops$698
Coxen Hole
Coxen Hole2 stops$572

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Sun, Apr 12 - Sun, Apr 19
Spirit Airlines Logo
6:28 pm - 12:04 am
MYR
-
GUA
7h 36m
1 stop
Spirit Airlines Logo
12:15 pm - 9:41 am
GUA
-
MYR
19h 26m
1 stop
$349Spirit Airlines
Sun, Apr 12 - Sun, Apr 19
Multiple Airlines Logo
12:05 pm - 12:04 am
MYR
-
GUA
13h 59m
2 stops
Multiple Airlines Logo
12:15 pm - 2:13 pm
GUA
-
MYR
23h 58m
1 stop
$405Multiple Airlines
Fri, May 29 - Sat, Jun 6
Multiple Airlines Logo
7:51 pm - 11:20 am
MYR
-
GUA
17h 29m
1 stop
Multiple Airlines Logo
6:15 pm - 5:48 pm
GUA
-
MYR
21h 33m
2 stops
$426Multiple Airlines
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
6:28 pm - 10:56 am
MYR
-
GUA
18h 28m
2 stops
Multiple Airlines Logo
12:15 pm - 3:43 pm
GUA
-
MYR
25h 28m
1 stop
$428Multiple Airlines
Tue, Apr 14 - Tue, Apr 21
Multiple Airlines Logo
12:05 pm - 10:56 am
MYR
-
GUA
24h 51m
1 stop
Multiple Airlines Logo
12:15 pm - 3:43 pm
GUA
-
MYR
25h 28m
1 stop
$431Multiple Airlines
Fri, May 1 - Fri, May 8
American Airlines Logo
6:30 pm - 12:46 pm
MYR
-
PTY
19h 16m
2 stops
American Airlines Logo
1:49 pm - 8:21 am
PTY
-
MYR
17h 32m
2 stops
$511American Airlines
Mon, May 25 - Fri, May 29
American Airlines Logo
4:17 pm - 12:28 pm
MYR
-
BZE
22h 11m
2 stops
American Airlines Logo
3:27 pm - 2:17 pm
BZE
-
MYR
20h 50m
2 stops
$520American Airlines
Tue, Mar 17 - Tue, Mar 31
Delta Logo
6:00 am - 11:15 am
MYR
-
BZE
7h 15m
1 stop
Delta Logo
12:40 pm - 12:04 am
BZE
-
MYR
9h 24m
1 stop
$640Delta
Fri, Jul 24 - Sun, Jul 26
Southwest Logo
7:25 am - 7:40 pm
MYR
-
SJO
14h 15m
2 stops
Southwest Logo
12:35 pm - 9:55 am
SJO
-
MYR
19h 20m
2 stops
$665Southwest
Sat, Jun 27 - Sat, Jul 4
GOL Logo
6:12 pm - 1:08 pm
MYR
-
SJO
20h 56m
2 stops
GOL Logo
11:59 pm - 3:38 pm
SJO
-
MYR
13h 39m
1 stop
$765GOL
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Central America were found on Spirit Airlines ($349) and American Airlines ($511).

Good to know

Low seasonAugust
Cheapest flight$245
Best time to beat the crowds with an average 29% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Myrtle Beach to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8237 reviews
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
8.1Boarding
Airline reviews

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

8.0 ExcellentSheila, Mar 2026
ATL - EWR
Read more Delta reviews

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Flight was warm for first few hours and quite rough

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

For my arriving destination, we were delayed multiple times to the point that we arrived 6 hours after we were originally scheduled. On my flight home, they overbooked and involuntarily removed passengers (including me) from the plane. It was not a good experience.

It was good experience this time. The flight was on time.

I very rarely fly American and my experience today reenforces that is the correct decision. While the staff were all very courteous, our flight was first thing in the morning so there was no reason to be delayed, yet appropriate maintenance checks weren’t completed prior to our flight so we were delayed multiple times. Not a great showing, American Airlines.

It's very confusing because Kayak has it as American Airlines, but it was Hawaiian Airlines, but operated by Alaska Airlines. I had to go to the airport for my boarding pass because American said I didn't have any trips.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Customer service online / on the phone are horrible. Flight crew is great but gate agents and customer service are terrible

bought basic spirit fares, add checked bags - like the up front info on website about this. bring your own snacks, buy a soda after TSA security to bring with you, or buy on the plane (limited selection) all in all, a good experience

I cannot effectively rate the food and drink as I had not. Otherwise, the trip was fine. The seats were nice, the crew was fine. They could smile once in a while. They all look like they were mad.

4 hour delay, 2 hours in the airport and then 2 hours on the tarmac. With a flight full of kids it would have been better to leave us in the airport for the delay, it was crying kids chaos on the flight. Miserable. And no apology or airline credit for the significant delay.

Flight was on time with no issues. Price is very competitive. Flight schedule works well for me

They charged late fees for selecting seats (no $0 options). They also changed my gate within the last half hour and are refusing to reimburse my costs to drive across the country with two small children in a rental car.

I was waiting in line for the restroom onboard, the flight attendant told me to step back two rows and stay on the carpet. She was rude and I expected a tik tok experience with me getting thrown off the plane. She was rude and frankly there was no where else to stand.

I needed a cheaper option than Southwest who are almost as bad as Spirit...did the check in the morning of the flight and assigned the last row, middle seat. Paid 20.00 at the airport for an exit row window in 19 and all 8 rows behind me which sold occupied on their seat map were empty....so they force to you to pay for a better seat....I was alone in row 19 and shortly after take off two huge fat people came and grabbed the other seats, I rang the call button for the attendant and said I paid 20.00 for this seat and they just moved in here...I either want to be reseated, or have them take their original seats or a refund of what I paid, the attendant made them move back to their original seats. Worst, worst worst airline in the air....never again, never again, never again.

It was cancelled a few hours before take off. Spirit has yet to confirm I will be refunded for the trip

gate agents with the different rules at the different airports. made me pay for my bag as a carry on instead of a personal item, yet it fit under the seat on the way from Indy to Ft Laud

Everything you need to know for your flight to Central America

Information on your arrival and departure airports