$220 Find Cheap Flights from Myrtle Beach to Central America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$621
San José
San José2 stops$593
Guatemala City
Guatemala City2 stops$687
Panama City
Panama City2 stops$631
Coxen Hole
Coxen Hole2 stops$642
San Salvador
San Salvador2 stops$621
San José
San José2 stops$593
Guatemala City
Guatemala City2 stops$687
Panama City
Panama City2 stops$631
Coxen Hole
Coxen Hole2 stops$642

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Fri, Oct 30 - Mon, May 3
Multiple Airlines Logo
6:12 pm - 7:55 amMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
15h 43m1 stop Tampa
Multiple Airlines Logo
7:00 am - 9:52 amSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
24h 52m1 stop Orlando
$530Multiple Airlines
Wed, Sep 16 - Sun, Sep 20
Southwest Logo
8:15 am - 6:45 pmMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
12h 30m2 stops Baltimore/Washington Houston Hobby
Southwest Logo
9:00 am - 9:30 pmSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
10h 30m2 stops Orlando Nashville Intl
$593Southwest
Fri, Oct 30 - Mon, May 3
Multiple Airlines Logo
10:17 am - 7:55 amMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
23h 38m2 stops Akron/Canton Tampa St. Petersburg
Multiple Airlines Logo
7:00 am - 9:52 amSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
24h 52m1 stop Orlando
$594Multiple Airlines
Fri, Sep 11 - Sun, Sep 13
Southwest Logo
6:40 am - 6:45 pmMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
14h 05m2 stops Baltimore/Washington Houston Hobby
Southwest Logo
9:00 am - 9:30 pmSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
10h 30m2 stops Orlando Nashville Intl
$604Southwest
Mon, Feb 1 - Tue, Mar 2
American Airlines Logo
10:48 am - 7:44 pmMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
9h 56m2 stops Philadelphia Miami
American Airlines Logo
12:23 am - 4:21 pmSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
14h 58m1 stop Dallas/Fort Worth
$613American Airlines
Mon, Feb 1 - Wed, Mar 3
American Airlines Logo
10:48 am - 7:44 pmMYR  Myrtle Beach Intl-SJO San José Juan Santamaria Intl
9h 56m2 stops Philadelphia Miami
American Airlines Logo
3:56 pm - 12:13 pmSJO  San José Juan Santamaria Intl-MYR Myrtle Beach Intl
19h 17m2 stops Miami Charlotte Douglas
$613American Airlines
Sun, Jan 24 - Sat, Jan 30
Delta Logo
6:00 am - 12:15 pmMYR  Myrtle Beach Intl-BZE Belize City Philip S.W.Goldson
7h 15m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:40 pm - 11:35 pmBZE  Belize City Philip S.W.Goldson-MYR Myrtle Beach Intl
8h 55m1 stop Atlanta Hartsfield-Jackson
$620Delta
Sun, Jan 24 - Sat, Jan 30
American Airlines Logo
6:23 am - 11:49 amMYR  Myrtle Beach Intl-BZE Belize City Philip S.W.Goldson
6h 26m1 stop Charlotte Douglas
American Airlines Logo
4:16 pm - 11:35 amBZE  Belize City Philip S.W.Goldson-MYR Myrtle Beach Intl
18h 19m2 stops Miami Charlotte Douglas
$629American Airlines
Sun, Jan 24 - Sat, Jan 30
Delta Logo
6:00 am - 12:15 pmMYR  Myrtle Beach Intl-BZE Belize City Philip S.W.Goldson
7h 15m1 stop Atlanta Hartsfield-Jackson
Delta Logo
1:40 pm - 11:35 pmBZE  Belize City Philip S.W.Goldson-MYR Myrtle Beach Intl
8h 55m1 stop Atlanta Hartsfield-Jackson
$634Delta
Wed, Oct 14 - Wed, Oct 21
Delta Logo
10:52 am - 12:59 pmMYR  Myrtle Beach Intl-PTY Panama City Tocumen Intl
27h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:24 pm - 10:57 pmPTY  Panama City Tocumen Intl-MYR Myrtle Beach Intl
7h 33m1 stop Atlanta Hartsfield-Jackson
$635Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Central America is May, when tickets cost $0 (return) on average. On the other hand, the most expensive months are August and December, when the average cost of round-trip tickets is $952 and $911 respectively.

Good to know

Low season

April

Cheapest flight

$220
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Myrtle Beach to San José

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8491 reviews
8.5Crew
7.8Entertainment
7.8Comfort
7.2Food
8.1Boarding
Airline reviews

the flight got cancelled - few hours before the departure time - no time to change

2.0 MediocreWojciech, Aug 2026
Read more Delta reviews

the flight got cancelled - few hours before the departure time - no time to change

This a short easy flight. No food or drink but that was not an issue since we were only in the air for 35 minutes.

Delta staff was exceptionally helpful and considerate. However, the first two of three flight legs were delayed making connections tentative and stressful.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

The only real hiccups in the flight were things beyond Delta’s control - turbulence which delayed food service and a departure delay caused by some VIP plane which stopped all departures and landings for 30 minutes - and was never explained to us by the crew. Otherwise good flight. I would fly Delta again.

The plane was frigid, and leaked water from the ceiling all over me and my seat.

Very good I can’t complain one bit. Thank you American Airlines for making my flight enjoyable and safe!

Flight was fine, but not having WiFi was a major negative

Everything was excellent and I enjoyed myself. Thank for everything

One of our group members was struggling to walk. In Charlotte we asked for a wheelchair and she was accompanied by Desmond. I was impressed by his patience and attention. In Boston she received the same service. I didn’t get the name of the helper but she went above and beyond in assisting us. A great AA service

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

Would have thought that they would gas up plane before everyone got on board

The flights were terribly delayed and then cancelled which forced us booking another night at the hotel. Very poor management from American Airlines

When my flight was delayed due to weather, I was rebooked to another flight since it showed that I would miss my connection. It was a lot of work to get back onto my originally connecting flight which was also delayed. That part caused a lot of stress and frustration. The ticketing agent at the desk was not very helpful.

American switched my flight to a 5 hour layover then cancelled my whole reservation with no notice and refused refund. Won’t fly with them again.

Flight was delayed 5 hours causing me to miss my connecting flights

Everything you need to know for your flight to Central America

Information on your arrival and departure airports