$145 Find Cheap Flights from Myrtle Beach to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Central America departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Myrtle Beach to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador2 stops$296
San José
San José1 stop$338
Guatemala City
Guatemala City1 stop$350
Panama City
Panama City2 stops$440
San Salvador
San Salvador2 stops$296
San José
San José1 stop$338
Guatemala City
Guatemala City1 stop$350
Panama City
Panama City2 stops$440

Book Cheap Myrtle Beach to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Central America

Sat, Feb 14 - Sun, Feb 22
Spirit Airlines Logo
9:09 am - 12:22 pm
MYR
-
SJO
28h 13m1 stop
Spirit Airlines Logo
1:31 pm - 8:13 am
SJO
-
MYR
17h 42m1 stop
$338Spirit Airlines
Fri, Jan 23 - Mon, Jan 26
Spirit Airlines Logo
8:15 pm - 12:29 pm
MYR
-
GUA
17h 14m1 stop
Spirit Airlines Logo
1:28 pm - 2:42 pm
GUA
-
MYR
24h 14m2 stops
$350Spirit Airlines
Sat, Feb 14 - Sun, Feb 22
Spirit Airlines Logo
9:09 am - 12:22 pm
MYR
-
SJO
28h 13m1 stop
Spirit Airlines Logo
12:35 pm - 8:13 am
SJO
-
MYR
18h 38m2 stops
$356Spirit Airlines
Thu, Feb 5 - Thu, Mar 5
American Airlines Logo
6:25 pm - 3:38 pm
MYR
-
PTY
21h 13m2 stops
American Airlines Logo
2:50 pm - 10:14 am
PTY
-
MYR
19h 24m2 stops
$440American Airlines
Wed, Apr 8 - Thu, Apr 16
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 5:58 pm
PTY
-
MYR
26h 38m1 stop
$443Delta
Sun, Feb 8 - Wed, Mar 4
Delta Logo
4:00 pm - 1:55 pm
MYR
-
PTY
21h 55m1 stop
Delta Logo
3:20 pm - 5:58 pm
PTY
-
MYR
26h 38m1 stop
$450Delta
Tue, Feb 3 - Tue, Mar 3
American Airlines Logo
12:05 pm - 1:27 pm
MYR
-
PTY
25h 22m2 stops
American Airlines Logo
2:50 pm - 11:49 am
PTY
-
MYR
20h 59m2 stops
$460American Airlines
Mon, May 18 - Fri, May 22
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 12:19 pm
PTY
-
MYR
20h 59m1 stop
$463Delta
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:35 pm - 2:22 pm
MYR
-
PTY
20h 47m2 stops
American Airlines Logo
1:44 pm - 10:01 am
PTY
-
MYR
19h 17m2 stops
$480American Airlines
Sat, Jan 31 - Sat, Feb 7
American Airlines Logo
5:44 pm - 3:38 pm
MYR
-
PTY
21h 54m2 stops
American Airlines Logo
5:00 pm - 11:44 am
PTY
-
MYR
18h 44m2 stops
$500American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Central America flights

Get data-powered insights and trends into flights from Myrtle Beach to Central America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Myrtle Beach and Central America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Myrtle Beach to Central America.

There are 3 airlines that fly nonstop from Myrtle Beach to Central America. They are: American Airlines, Delta and Spirit Airlines. The cheapest price of all airlines flying this route was found with Spirit Airlines at $267 for a round-trip flight to San José (SJO). On average, Spirit Airlines offers the best prices for nonstop flights between Myrtle Beach and Central America.

Which airlines provide the cheapest flights from Myrtle Beach to Central America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Central America were found on Spirit Airlines ($346) and Delta ($450).

Good to know

Low seasonAugust
Cheapest flight$145
Best time to beat the crowds with an average 27% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Myrtle Beach to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Myrtle Beach to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Myrtle Beach to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Myrtle Beach to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Central America?

    The cheapest time of day to fly to Central America is generally in the morning, when round-trip flights cost $724 on average. The most expensive time of day to fly to Central America is generally in the morning, which is peak travel time and where the average cost of a ticket is $724.

Reviews of the top 3 airlines serving from Myrtle Beach to Central America

 
Need help choosing which airline to fly with from Myrtle Beach to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8008 reviews
7.9Entertainment
7.3Food
8.5Crew
8.1Boarding
7.9Comfort
Airline reviews

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

10.0 ExcellentMargaret, Dec 2025
BOS - PIT
Read more Delta reviews

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Flight was late and boarding was confusing because gate changed and I didn’t get a notification

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Not comparable to Qatar Airways services on flights to Doha. Flight attendants provided basic services; I was never recognized by name or as an Executive Platinum member. Restrooms were not kept clean during the flight.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Horrible. Arrived at my gate at 6:37 for a 6:50 flight and was denied by staff to board. Literally watched my flight leave from the window and it didn’t take off until after 7am. Tried to talk to staff and they were rude beyond compare. Will never fly with this airline again.

Our flight got rescheduled 48 hours later, the airline didn’t pay a penny for our expenses.

We had to sit and wait for almost an hour after landing and taxiing to the gate. The jet bridge was broken so we just waited and waited and waited and it was inconvenient, hot, and unnecessary.

Flight was in time, very smooth ride and surprisingly lots of legroom in the cabin so I certainly will fly with spirit again

The seats are the most uncomfortable seats I’ve ever sat in. Don’t believe I’ll ever fly spirit again!!

Flight was canceled and instead of rescheduling at the gate we had to go out to the ticket counter. Unruly kids kicking the back of my rows chair with staff to inattentive to say something.

Customer feedback I sent to Spirited today: “I will never fly Spirit Airlines again and will work hard to convince my friends and family to boycott/avoid Spirit Airlines at all costs. I booked three seats for me and my 8 and 10 year old children on NK 1222 from Orlando to Kansas City for 12/7/25 leaving Orlando at 10:37AM. This itinerary was abandoned by Spirit and we were rebooked onto Spirit flight NK 213 leaving at 9:06PM without any notice. Then the nightmare really began. Flight 213 was delayed a total of 12 times, finally leaving at 6:35AM the following day. The gate was changed 5 times and our electronic boarding passes were invalidated at midnight. The worst part was that the 12 separate delays were incremental making it impossible to plan for accommodations for my family. My kids missed a day of school and barely slept under the harsh lights with lots of noise on the filthy airport floor. The customer service agent at Spirit Airlines told us we would be emailed a voucher for a hotel which never happened. I asked about it multiple times and it never arrived in my email inbox. This whole unfortunate situation could’ve been avoided if spirit had taken a realistic approach and delayed the flight from 9 PM until 6 AM from the beginning. My son gleefully deleted the Spirit app from my phone once we landed and we will never fly with Spirit again.”

Honestly horrible. The plane on the way back was delayed 6 times with no explanation on why. When I asked for a refund or some money back because I had to miss a day of work because of the desk, they told me no. Because of how poorly it was handled I will most likely never take spirit again

I love a flight without turbulence and you guys deliver It’d be nice to have comfier seats and maybe some inflight entertainment and snacks but that’s for Delta

30 minute delay, Also there was a medical emergency on the flight. The flight crew was on top of the situation and assisted the medical professionals that happened to be on the flight.

Everything you need to know for your flight to Central America

Information on your arrival and departure airports