MYR - PTY

$460 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$460
American Airlines
Wed 5/6Mon 5/11
MYR - PTY • 2 stops
Cheapest one-way
Multiple Airlines
Tue 12/9
MYR - PTY • multi-stop
Top airlines
American Airlines
Cheapest • from $460 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Wed, May 6 - Mon, May 11
American Airlines Logo
6:26 pm - 12:15 pm
MYR
-
PTY
18h 49m2 stops
American Airlines Logo
1:55 pm - 11:37 am
PTY
-
MYR
20h 42m2 stops
$460American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:35 pm - 2:22 pm
MYR
-
PTY
20h 47m2 stops
American Airlines Logo
1:44 pm - 11:39 am
PTY
-
MYR
20h 55m2 stops
$480American Airlines
Wed, May 6 - Mon, May 11
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:38 pm
PTY
-
MYR
8h 18m1 stop
$578Delta
Sat, Jun 6 - Thu, Jun 11
American Airlines Logo
6:17 pm - 12:25 pm
MYR
-
PTY
19h 08m2 stops
American Airlines Logo
1:50 pm - 10:01 am
PTY
-
MYR
19h 11m2 stops
$670American Airlines
Thu, Mar 19 - Thu, Mar 26
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:59 pm
PTY
-
MYR
8h 39m1 stop
$868Delta
Sat, Jun 6 - Thu, Jun 11
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:38 pm
PTY
-
MYR
8h 18m1 stop
$967Delta
Wed, May 6 - Mon, May 11
American Airlines Logo
5:28 am - 12:15 pm
MYR
-
PTY
7h 47m2 stops
American Airlines Logo
1:55 pm - 8:14 am
PTY
-
MYR
17h 19m3 stops
$2,255American Airlines
Wed, May 6 - Wed, May 6
United Airlines Logo
11:25 am - 7:31 pm
MYR
-
PTY
9h 06m1 stop
United Airlines Logo
10:29 pm - 4:49 pm
PTY
-
MYR
17h 20m2 stops
$3,950United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Panama City?

The average price of all round-trip flights from Myrtle Beach to Panama City clicked on KAYAK for each day over the last 12 months.

For Myrtle Beach to Panama City, Wednesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Panama City back to Myrtle Beach, the best deals are generally found on Monday, with Wednesday being the most expensive.

Find deals

Good to know

Cheapest flight$460
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $460 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    Yes, you’ll need a passport to travel to Panama City from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Panama City?

    On your way to Panama City, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11045 reviews
6.9Entertainment
7.2Comfort
8.0Crew
7.5Boarding
6.5Food
Airline reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

8.0 ExcellentConnie, Dec 2025
PHX - MKE
Read more American Airlines reviews

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

After arriving in Dallas, the aircraft taxied for an unusually long time and was unable to park at the gate, which caused a significant delay and made me miss my connecting flight. I then had to wait in a very long line to be rebooked, and I was told that no hotel or meal accommodations would be provided. What is even more unacceptable is that my luggage was mishandled and has still not been located. My suitcase contains important medications that I urgently need, and I have been unable to access them due to the airline’s mishandling. This situation has caused me considerable stress and inconvenience, and I need this issue to be resolved immediately.

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports

Myrtle Beach (MYR)
Panama City (PTY)