MYR - PTY

$460 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$460
American Airlines
Thu 1/22Mon 1/26
MYR - PTY • 2 stops
Cheapest one-way
Multiple Airlines
Sat 11/22
MYR - PTY • multi-stop
Top airlines
American Airlines
Cheapest • from $460 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Thu, Jan 22 - Mon, Jan 26
American Airlines Logo
6:23 am - 3:38 pmMYR-PTY
9h 15m2 stops
American Airlines Logo
4:50 pm - 10:18 amPTY-MYR
17h 28m2 stops
$460American Airlines
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Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:40 pm - 2:20 pmMYR-PTY
20h 40m2 stops
American Airlines Logo
1:50 pm - 9:52 amPTY-MYR
19h 02m2 stops
$480American Airlines
Find Deal
Mon, Mar 2 - Sat, Mar 7
American Airlines Logo
6:38 pm - 1:40 pmMYR-PTY
19h 02m2 stops
American Airlines Logo
2:52 pm - 9:21 amPTY-MYR
18h 29m2 stops
$530American Airlines
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Sat, Dec 6 - Sun, Dec 14
Delta Logo
6:00 am - 7:59 pmMYR-PTY
13h 59m1 stop
Delta Logo
8:05 am - 6:01 pmPTY-MYR
9h 56m1 stop
$556Delta
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Sat, Dec 6 - Sun, Dec 14
American Airlines Logo
8:11 pm - 3:42 pmMYR-PTY
19h 31m2 stops
American Airlines Logo
4:43 pm - 11:39 amPTY-MYR
18h 56m2 stops
$565American Airlines
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Sat, Dec 6 - Sat, Dec 13
Multiple Airlines Logo
9:54 am - 1:00 amMYR-PTY
15h 06m2 stops
Multiple Airlines Logo
2:55 am - 7:32 pmPTY-MYR
16h 37m2 stops
$604Multiple Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
9:53 am - 4:55 pmMYR-PTY
31h 02m3 stops
Multiple Airlines Logo
2:55 am - 2:34 pmPTY-MYR
35h 39m3 stops
$616Multiple Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
Multiple Airlines Logo
9:53 am - 4:55 pmMYR-PTY
31h 02m3 stops
Multiple Airlines Logo
2:55 am - 7:20 pmPTY-MYR
16h 25m2 stops
$645Multiple Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 14
Multiple Airlines Logo
9:54 am - 1:00 amMYR-PTY
15h 06m2 stops
Multiple Airlines Logo
2:55 pm - 5:48 pmPTY-MYR
26h 53m3 stops
$745Multiple Airlines
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Sat, Dec 6 - Sun, Dec 14
Multiple Airlines Logo
9:54 am - 8:19 pmMYR-PTY
10h 25m1 stop
Multiple Airlines Logo
11:25 am - 5:48 pmPTY-MYR
30h 23m2 stops
$765Multiple Airlines
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Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Panama City?

The average price of all round-trip flights from Myrtle Beach to Panama City clicked on KAYAK for each day over the last 12 months.

For Myrtle Beach to Panama City, Wednesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Panama City back to Myrtle Beach, the best deals are generally found on Monday, with Wednesday being the most expensive.

Find deals

Good to know

Cheapest flight$460
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $460 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    Yes, you’ll need a passport to travel to Panama City from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Panama City?

    On your way to Panama City, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    oneworld is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11048 reviews
7.5Boarding
6.9Entertainment
8.0Crew
7.2Comfort
6.4Food
Airline reviews

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

8.0 ExcellentShirley, Nov 2025ILM - CLT
Read more American Airlines reviews

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports

Myrtle Beach (MYR)
Panama City (PTY)