MYR - SFO

$169 Find Cheap Flights from Myrtle Beach to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$337
Typical prices: $364-$499
Delta
Tue 9/29Sat 10/3
MYR - SFO • 1 stop
Cheapest one-way
$169
Typical prices: $191-$216
Southwest
Sat 9/12
MYR - SFO • 1 stop
Top airlines
Cheapest • from $337 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
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Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Francisco. You'll need at least 1 connection.
Insights
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Insights
Top layover airports
Cheapest • Avg $514 (round-trip)
Shortest trip • 8h 09m (one-way)
Insights
Insights
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Insights
When to travel
Cheapest • 29% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

Tue, Sep 29 - Sat, Oct 3
Delta Logo
6:59 pm - 11:57 pm
MYR
-
SFO
7h 58m
1 stop
Delta Logo
10:59 pm - 10:37 am
SFO
-
MYR
8h 38m
1 stop
$337Delta
Mon, Nov 2 - Thu, Nov 12
Delta Logo
6:58 pm - 12:15 am
MYR
-
SFO
8h 17m
1 stop
Delta Logo
9:30 pm - 10:08 am
SFO
-
MYR
9h 38m
1 stop
$339Delta
Wed, Aug 26 - Tue, Sep 1
Southwest Logo
8:15 am - 4:25 pm
MYR
-
SFO
11h 10m
2 stops
Southwest Logo
10:30 pm - 10:05 am
SFO
-
MYR
8h 35m
1 stop
$342Southwest
Wed, Aug 26 - Tue, Sep 1
Southwest Logo
8:15 am - 4:25 pm
MYR
-
SFO
11h 10m
2 stops
Southwest Logo
7:10 pm - 10:05 am
SFO
-
MYR
11h 55m
2 stops
$347Southwest
Wed, Aug 12 - Mon, Aug 17
American Airlines Logo
6:15 am - 11:28 am
MYR
-
SFO
8h 13m
1 stop
American Airlines Logo
11:40 pm - 9:40 am
SFO
-
MYR
7h 00m
1 stop
$355American Airlines
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
2:30 pm - 9:30 pm
MYR
-
SFO
10h 00m
2 stops
Southwest Logo
10:30 pm - 10:05 am
SFO
-
MYR
8h 35m
1 stop
$360Southwest
Mon, Nov 2 - Thu, Nov 12
Southwest Logo
1:40 pm - 12:20 am
MYR
-
SFO
13h 40m
2 stops
Southwest Logo
9:25 pm - 10:05 am
SFO
-
MYR
9h 40m
1 stop
$361Southwest
Fri, Sep 11 - Mon, Sep 14
Southwest Logo
6:40 am - 2:10 pm
MYR
-
SFO
10h 30m
2 stops
Southwest Logo
7:55 pm - 10:05 am
SFO
-
MYR
11h 10m
2 stops
$365Southwest
Mon, Nov 2 - Thu, Nov 12
Southwest Logo
1:40 pm - 11:20 pm
MYR
-
SFO
12h 40m
2 stops
Southwest Logo
8:00 am - 10:00 pm
SFO
-
MYR
11h 00m
2 stops
$366Southwest
Wed, Jul 29 - Wed, Aug 5
Southwest Logo
7:00 am - 1:40 pm
MYR
-
SFO
9h 40m
1 stop
Southwest Logo
7:55 pm - 10:15 am
SFO
-
MYR
11h 20m
2 stops
$373Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to San Francisco departing in September.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is October, where tickets cost $390 (return) on average. On the other hand, the most expensive months are April and November, where the average cost of round-trip tickets is $731 and $691 respectively.

Good to know

Low seasonNovember
Cheapest flight$169
Best time to beat the crowds but there is an average 26% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to San Francisco was $169 for a one-way ticket and $337 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Southwest and Delta. With an average price for the route of $587 and an overall rating of 7.9, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $472 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4250 reviews
7.5Entertainment
8.1Boarding
8.6Crew
7.0Food
8.0Comfort
Airline reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

2.0 MediocreIrene, Jun 2026
DEN - SFO
Read more Southwest reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

It was just okay, no frills, basic transportation with no luxury. No screens on the seats, no water or drinks on a short flight. Full flight but at least it was on time.

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

Can not wait for seating change to reduce the amount of pre boards - it’s disheartening the abuse. And then then deplaning

Flight was delayed more than 2 hour do the scheduling issues and then some confusing weight and balance matters, followed by a miscommunication with the tower on which runway was going to be used based on the airplane weight. All these things should have been figured out in advance. Instead of arriving at 12:30 a.m. we arrived at 2:30 a.m. very difficult to find a taxi or other transport at SFO. Luggage was delayed. An extension of an unpleasant flight day

I think Southwest can offer a whole can of beverage instead of such a small cup

The crew was fabulous, outstanding, friendly, attentive and just great, really made my flight one of the best I've ever had, thank you southwest crew flight #474, from Los Angeles to San Francisco on April 2,2024

We sat on the runway for over an hour before departure. That was unwelcome.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

The flight attendant was very polite and attentive. The food was good.

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Long 5 hour and 45 min flight and only one drink service and cookie snack

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

We boarded after several delays due to mechanical failure and a gate change. The seat cushion in the exit row was very compressed and offered no cushion, making the four-hour journey reasonably uncomfortable. The WiFi worked for a few people, but for most, it did not, and you cannot get entertainment unless you can connect—American Airlines flights do not have seatback screens, and you must use your mobile phone.

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports