MYR - SFO

$167 Find Cheap Flights from Myrtle Beach to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

Wed, Oct 8 - Wed, Oct 22
American Airlines Logo
12:18 pm - 7:55 pmMYR-SFO
10h 37m2 stops
American Airlines Logo
7:04 am - 6:45 pmSFO-MYR
8h 41m1 stop
$342American Airlines
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Wed, Oct 8 - Wed, Oct 22
American Airlines Logo
4:47 pm - 11:29 pmMYR-SFO
9h 42m1 stop
American Airlines Logo
7:04 am - 6:45 pmSFO-MYR
8h 41m1 stop
$348American Airlines
Find Deal
Thu, Oct 30 - Sat, Nov 1
Southwest Logo
6:55 am - 3:25 pmMYR-SFO
11h 30m2 stops
Southwest Logo
4:35 pm - 11:35 amSFO-MYR
16h 00m2 stops
$375Southwest
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Wed, Jan 28 - Sun, Feb 15
Southwest Logo
3:00 pm - 10:20 pmMYR-SFO
10h 20m2 stops
Southwest Logo
6:25 am - 6:00 pmSFO-MYR
8h 35m1 stop
$397Southwest
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Wed, Oct 1 - Sun, Oct 5
Multiple Airlines Logo
1:15 pm - 8:44 amMYR-SFO
22h 29m2 stops
Multiple Airlines Logo
12:50 pm - 2:42 pmSFO-MYR
22h 52m1 stop
$439Multiple Airlines
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Tue, Mar 10 - Wed, Mar 11
Delta Logo
2:15 pm - 9:46 pmMYR-SFO
10h 31m1 stop
Delta Logo
7:30 am - 5:56 pmSFO-MYR
7h 26m1 stop
$447Delta
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Mon, Oct 13 - Fri, Oct 17
Multiple Airlines Logo
9:04 pm - 12:05 pmMYR-SFO
18h 01m1 stop
Multiple Airlines Logo
4:55 pm - 5:49 pmSFO-MYR
21h 54m2 stops
$504Multiple Airlines
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Tue, Mar 10 - Wed, Mar 11
Delta Logo
6:45 pm - 7:58 amMYR-SFO
16h 13m2 stops
Delta Logo
9:30 pm - 10:08 amSFO-MYR
9h 38m1 stop
$505Delta
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Tue, Oct 21 - Fri, Oct 24
United Airlines Logo
4:33 pm - 7:45 amMYR-SFO
18h 12m2 stops
United Airlines Logo
8:52 pm - 2:31 pmSFO-MYR
14h 39m2 stops
$576United Airlines
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Wed, Oct 1 - Sun, Oct 5
United Airlines Logo
11:20 am - 5:41 pmMYR-SFO
9h 21m1 stop
United Airlines Logo
8:52 pm - 2:42 pmSFO-MYR
14h 50m2 stops
$751United Airlines
Find Deal

Everything you should know

Top airlines
American Airlines
Cheapest • from $342 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
April
Cheapest • 17% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$342
Overall average: $418
American Airlines
Wed 10/8Wed 10/22
MYR - SFO • 2 stops
Cheapest one-way
$167
Typical prices: $301-376
Multiple Airlines
Wed 10/1
MYR - SFO • 2 stops
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to San Francisco?

The average price of all round-trip flights from Myrtle Beach to San Francisco clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to San Francisco, you should consider leaving on a Thursday and avoid Sundays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Wednesdays and the most expensive ones on Thursdays.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is April, where tickets cost $368 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $526 and $506 respectively.

Good to know

Low seasonFebruary
Cheapest flight$167
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Francisco was $167 for a one-way ticket and $342 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Delta and American Airlines. With an average price for the route of $414 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $461 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7961 reviews
7.3Food
7.9Entertainment
8.5Crew
8.2Boarding
7.9Comfort
Airline reviews

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

6.0 GoodBarbie, Aug 2025MSP - SFO
Read more Delta reviews

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Food was surprisingly good but the WiFi was not great

My flight was extremely cold. I had a jacket and a cover was left in each seat. The cover was extremely thin and I have a disability, fibromyalgia and arthrithis and AC air is the worst. I closed my vent and my husbands vent and it still was frigid. I asked the attendant if I could get another cover and she quickly almost dismissively and totally unconcerned stating, (I quote) (one per chair) and walked off so quickly that I didn't get a chance to explain to her that I literally have adisability. I didnt want to make a seen so I set on that flight for over 5 hours in pain, joints locking up and extremely uncomfortable. When my fibromyalgia flares up my joints not only ache but they will lock up also and it takes me days to get back to my regular self even though I take medication for it. I felt like it would not have hurt anyone at all for her to just give me an extra cover because I'm sure they have all types of medical issues in people that fly every day.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports

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