MYR - SFO

$166 Find Cheap Flights from Myrtle Beach to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$397
Typical prices: $481-$368
United Airlines
Tue 4/21Tue 4/28
MYR - SFO • 1 stop
Cheapest one-way
$166
Typical prices: $178-$315
Multiple Airlines
Tue 5/5
MYR - SFO • 2 stops
Top airlines
Cheapest • from $397 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $472 (round-trip)
Shortest trip • 7h 58m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 20% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

Tue, Apr 21 - Tue, Apr 28
United Airlines Logo
11:57 am - 8:34 pm
MYR
-
SFO
11h 37m
1 stop
United Airlines Logo
11:52 pm - 10:18 am
SFO
-
MYR
7h 26m
1 stop
$397United Airlines
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
4:05 pm - 8:55 pm
MYR
-
SFO
7h 50m
1 stop
Southwest Logo
5:25 am - 8:30 pm
SFO
-
MYR
12h 05m
2 stops
$402Southwest
Thu, Apr 23 - Tue, Apr 28
Delta Logo
12:50 pm - 7:03 pm
MYR
-
SFO
9h 13m
1 stop
Delta Logo
10:55 pm - 11:55 am
SFO
-
MYR
10h 00m
1 stop
$406Delta
Tue, Apr 21 - Tue, Apr 28
Southwest Logo
2:10 pm - 10:10 pm
MYR
-
SFO
11h 00m
2 stops
Southwest Logo
6:20 am - 5:35 pm
SFO
-
MYR
8h 15m
2 stops
$407Southwest
Thu, Apr 23 - Tue, Apr 28
Southwest Logo
3:45 pm - 12:10 am
MYR
-
SFO
11h 25m
2 stops
Southwest Logo
9:15 pm - 10:35 am
SFO
-
MYR
10h 20m
1 stop
$411Southwest
Wed, May 20 - Wed, May 27
American Airlines Logo
6:30 pm - 11:15 pm
MYR
-
SFO
7h 45m
1 stop
American Airlines Logo
6:54 pm - 8:41 am
SFO
-
MYR
10h 47m
2 stops
$412American Airlines
Thu, Apr 23 - Tue, Apr 28
Southwest Logo
3:45 pm - 12:10 am
MYR
-
SFO
11h 25m
2 stops
Southwest Logo
5:40 am - 8:30 pm
SFO
-
MYR
11h 50m
2 stops
$416Southwest
Thu, May 14 - Sat, May 16
Southwest Logo
3:45 pm - 12:10 am
MYR
-
SFO
11h 25m
2 stops
Southwest Logo
11:25 pm - 4:10 pm
SFO
-
MYR
13h 45m
1 stop
$417Southwest
Wed, May 20 - Wed, May 27
Southwest Logo
7:35 am - 7:55 pm
MYR
-
SFO
15h 20m
2 stops
Southwest Logo
7:15 pm - 10:05 am
SFO
-
MYR
11h 50m
2 stops
$422Southwest
Thu, May 14 - Sat, May 16
Southwest Logo
3:45 pm - 12:10 am
MYR
-
SFO
11h 25m
2 stops
Southwest Logo
5:40 am - 6:15 pm
SFO
-
MYR
9h 35m
2 stops
$425Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to San Francisco departing in April.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is October, where tickets cost $390 (return) on average. On the other hand, the most expensive months are November and December, where the average cost of round-trip tickets is $691 and $667 respectively.

Good to know

Low seasonNovember
Cheapest flight$166
Best time to beat the crowds but there is an average 41% increase in price.
Most popular time to fly and prices are also 20% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Francisco was $166 for a one-way ticket and $396 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Delta and American Airlines. With an average price for the route of $472 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $450 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8368 reviews
8.5Crew
7.8Entertainment
7.9Comfort
8.1Boarding
7.2Food
Airline reviews

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

10.0 ExcellentViraj, Apr 2026
JFK - SFO
Read more Delta reviews

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The cabin temperature was nice and cool. The wifi was not working.

As previously noted, this flight was great: departure was timely, the crew was friendly and attentive, and wifi connectivity was seamless. In particular, I appreciated that the flight attendant just told me to stow the laptop right before takeoff/landing, and trusted me to do so (which I did!).

Left a few minutes early. Got in 15 minutes early. Very attentive service on board. Very organized boarding.

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Awful - both legs. The check in was awful, getting on the plane required walking down a spiral staircase (dangerous), then taking a bus about 5 miles out from the terminal. The seat was broken (I was in business), there was no internet during the flight (both legs). The aircraft was very old. I saw rust in some place, tape holding things up in the bathroom. This was an unacceptable experience for such a long haul flight.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports