MYR - SFO

$156 Find Cheap Flights from Myrtle Beach to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$403
Typical prices: $536-$406
Southwest
mar. 9/15mar. 9/29
MYR - SFO • 1 stop
Cheapest one-way
$156
Typical prices: $209-$366
Multiple Airlines
lun. 8/10
MYR - SFO • 2 stops
Top airlines
Cheapest • from $403 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $514 (round-trip)
Shortest trip • 7h 59m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 29% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

mar., sep. 15 - mar., sep. 29
Southwest Logo
11:00 am - 4:25 pm
MYR
-
SFO
8h 25m
1 stop
Southwest Logo
10:30 pm - 10:05 am
SFO
-
MYR
8h 35m
1 stop
$403Southwest
mar., sep. 15 - mar., sep. 29
Southwest Logo
7:50 am - 12:55 pm
MYR
-
SFO
8h 05m
1 stop
Southwest Logo
7:55 pm - 10:05 am
SFO
-
MYR
11h 10m
2 stops
$408Southwest
mar., sep. 15 - mar., sep. 29
Southwest Logo
8:15 am - 4:25 pm
MYR
-
SFO
11h 10m
2 stops
Southwest Logo
6:50 am - 7:20 pm
SFO
-
MYR
9h 30m
2 stops
$413Southwest
vie., jul. 10 - mié., jul. 15
Southwest Logo
7:15 pm - 12:10 am
MYR
-
SFO
7h 55m
1 stop
Southwest Logo
9:10 pm - 9:55 am
SFO
-
MYR
9h 45m
1 stop
$435Southwest
mié., jul. 1 - lun., jul. 6
Southwest Logo
7:00 am - 1:40 pm
MYR
-
SFO
9h 40m
1 stop
Southwest Logo
5:10 am - 7:30 pm
SFO
-
MYR
11h 20m
2 stops
$440Southwest
mié., jul. 1 - lun., jul. 6
Southwest Logo
10:25 am - 4:40 pm
MYR
-
SFO
9h 15m
2 stops
Southwest Logo
6:10 pm - 9:50 am
SFO
-
MYR
12h 40m
2 stops
$445Southwest
sáb., ago. 8 - jue., sep. 10
American Airlines Logo
4:23 pm - 9:13 pm
MYR
-
SFO
7h 50m
1 stop
American Airlines Logo
5:51 am - 5:17 pm
SFO
-
MYR
8h 26m
1 stop
$460American Airlines
mar., jul. 7 - vie., jul. 10
Southwest Logo
2:10 pm - 10:25 pm
MYR
-
SFO
11h 15m
2 stops
Southwest Logo
9:10 pm - 9:55 am
SFO
-
MYR
9h 45m
1 stop
$468Southwest
mar., jul. 7 - vie., jul. 10
American Airlines Logo
6:10 pm - 10:48 pm
MYR
-
SFO
7h 38m
1 stop
American Airlines Logo
5:00 am - 5:25 pm
SFO
-
MYR
9h 25m
1 stop
$472American Airlines
mar., jul. 7 - vie., jul. 10
Southwest Logo
2:10 pm - 10:25 pm
MYR
-
SFO
11h 15m
2 stops
Southwest Logo
5:10 am - 7:30 pm
SFO
-
MYR
11h 20m
2 stops
$473Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to San Francisco departing in September.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is October, where tickets cost $390 (return) on average. On the other hand, the most expensive months are November and July, where the average cost of round-trip tickets is $691 and $669 respectively.

Good to know

Low seasonNovember
Cheapest flight$156
Best time to beat the crowds but there is an average 26% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Francisco was $156 for a one-way ticket and $403 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Delta or Southwest?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Delta and Southwest. With an average price for the route of $472 and an overall rating of 7.9, Delta is the most popular choice. Southwest is also a great choice for the route, with an average price of $587 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4287 reviews
8.1Boarding
7.0Food
7.5Entertainment
8.0Comfort
8.6Crew
Airline reviews

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

10.0 ExcellentRobert, May 2026
LAS - SFO
Read more Southwest reviews

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Not having a five hour delay with little notice! The crew was very kind, though, and just as tired as we passengers were. The flight didn't depart until nearly 1 am...and no reason was ever given.

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

Boarding was easy. The seats are small and fairly uncomfortable

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

The charges were ridiculous for an hour flight and the turbulence was very scary.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

American Airlines is a miserable experience. It is predictably miserable, in the sense that every time I fly American, I brace myself for the certainty that it will be unpleasant and uncomfortable. But it is unpredictable in the sense that I never know if the flight will be on time or delayed nine hours (both happened to me this week). I never know if I will be able to sit in the seat that I selected when I purchased the ticket or if I will be told by Customer Service (!!!) that I must relocate from first class to a seat in the back of the aircraft with no explanation (both happened to me this week). Will the food be frozen and half defrosted, or scalding hot? Will the drinks be warm? Will the flight attendants be surly and mean? Will the toilets be cramped and foul? Will the seats be narrow and uncomfortable? Will there be a real electric outlet at the seat, or just an unreliable USB-2 port? Will there be enough seats in the boarding lounge or just a few? Will the boarding process be smooth and efficient, or will the gate agents mess it up and delay it needlessly for 30 or 40 minutes? Will the catering and cleaning crew be prompt or will they take an extra 30 minutes? Will the brakes on the aircraft work properly, or will the pilot delay takeoff for four hours while the ground crew attends to what can only be described as routine maintenance that should have been done the night before? I've eexperienced every one of these unpleasant things this year, 2026. The only thing I can reliably count on is that American will find a new way to make the experience of flying as miserable as they possibly can.

Wifi was spotty. Tray table was very dirty when I sat down.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

Delayed for mechanical and no updates on what was happening and how long the delay might be.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports