MYR - SFO

$157 Find Cheap Flights from Myrtle Beach to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$383
Typical prices: $677-$436
Delta
Wed 6/17Tue 6/23
MYR - SFO • 1 stop
Cheapest one-way
$157
Typical prices: $178-$233
Multiple Airlines
Mon 5/11
MYR - SFO • 2 stops
Top airlines
Cheapest • from $383 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $472 (round-trip)
Shortest trip • 8h 00m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 23% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

Wed, Jun 17 - Tue, Jun 23
Delta Logo
6:00 am - 10:27 am
MYR
-
SFO
7h 27m
1 stop
Delta Logo
10:59 pm - 10:44 am
SFO
-
MYR
8h 45m
1 stop
$383Delta
Wed, May 6 - Sat, May 9
Southwest Logo
2:10 pm - 9:25 pm
MYR
-
SFO
10h 15m
1 stop
Southwest Logo
9:15 pm - 9:45 am
SFO
-
MYR
9h 30m
1 stop
$390Southwest
Wed, Jun 17 - Tue, Jun 23
Southwest Logo
10:25 am - 4:40 pm
MYR
-
SFO
9h 15m
2 stops
Southwest Logo
5:10 am - 9:45 pm
SFO
-
MYR
13h 35m
1 stop
$394Southwest
Wed, May 6 - Sat, May 9
Southwest Logo
4:05 pm - 8:55 pm
MYR
-
SFO
7h 50m
1 stop
Southwest Logo
6:15 am - 8:45 pm
SFO
-
MYR
11h 30m
2 stops
$395Southwest
Sat, May 9 - Sat, May 16
Delta Logo
1:30 pm - 7:05 pm
MYR
-
SFO
8h 35m
1 stop
Delta Logo
1:45 pm - 11:58 pm
SFO
-
MYR
7h 13m
1 stop
$397Delta
Wed, May 6 - Sat, May 9
Southwest Logo
4:05 pm - 11:15 pm
MYR
-
SFO
10h 10m
2 stops
Southwest Logo
11:25 pm - 1:40 pm
SFO
-
MYR
11h 15m
2 stops
$400Southwest
Sat, May 9 - Sat, May 16
Southwest Logo
11:50 am - 9:20 pm
MYR
-
SFO
12h 30m
2 stops
Southwest Logo
5:40 am - 6:15 pm
SFO
-
MYR
9h 35m
2 stops
$407Southwest
Sat, May 9 - Sat, May 16
Southwest Logo
7:10 am - 4:20 pm
MYR
-
SFO
12h 10m
2 stops
Southwest Logo
11:25 pm - 4:10 pm
SFO
-
MYR
13h 45m
1 stop
$417Southwest
Wed, Jun 17 - Tue, Jun 23
Southwest Logo
10:25 am - 4:40 pm
MYR
-
SFO
9h 15m
2 stops
Southwest Logo
5:10 am - 9:45 pm
SFO
-
MYR
13h 35m
1 stop
$422Southwest
Tue, May 12 - Sun, May 17
American Airlines Logo
12:19 pm - 7:07 pm
MYR
-
SFO
9h 48m
1 stop
American Airlines Logo
10:28 pm - 8:24 am
SFO
-
MYR
6h 56m
1 stop
$425American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to San Francisco departing in June.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is October, where tickets cost $392 (return) on average. On the other hand, the most expensive months are November and December, where the average cost of round-trip tickets is $691 and $667 respectively.

Good to know

Low seasonApril
Cheapest flight$157
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly and prices are also 24% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Francisco was $157 for a one-way ticket and $383 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Southwest and Delta. With an average price for the route of $587 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $472 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4331 reviews
8.6Crew
7.5Entertainment
8.0Comfort
8.1Boarding
7.0Food
Airline reviews

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

4.0 Okaysangeetha, Apr 2026
AUS - SJC
Read more Southwest reviews

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

Boarding was easy. The seats are small and fairly uncomfortable

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

No food or entertainment, just a quick 40 minute flight. A little bumpy due to Santa Ana winds but pilot has no control over that. Good flight and landing!

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

The charges were ridiculous for an hour flight and the turbulence was very scary.

3 hour delay. Had to change plans and was still delayed.

The flight crew was extremely rude and especially not helpful when our flight was delayed.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

WiFi didn’t work most of the time. The usb chargers would work only occasionally for 5 mins and wouldn’t charge after that. Had to keep trying repeatedly at each of the seats in the row.

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

The cabin temperature was nice and cool. The wifi was not working.

Wifi was spotty. Tray table was very dirty when I sat down.

The WiFi would not connect enough for me to do my actual work. It permaspooled, disconnected, said it was connected, then wouldn't open an email... it was frustrating. I am not a tall person, 5'4" - and I felt cramped with little room to reach into my bag under the seat in front of me. I feel sorry for anyone taller than me having to fly. the one positive thing I will add, is the overhead bins are roomy enough to manage more bags than other carriers.

Buying ticket from kayak instant booking was a huge mistake, never to be repeated again! The Kayak didn’t book the tickets directly, it handed it off to a third party Underpricer, that booked a code shared American Airlines flight operated by Cathay Pacific!! When managing the booking American Airlines would recognize the itinerary but wouldn’t let me do anything stating, the flight is operated by Cathay Pacific so go to their website. Cathay Pacific would recognize the itinerary, neither by reservation ID or ticket number…asking to reach out to the third party Underpricer….calling Underpricer resulted in no help like seat requests, mileage number or upgrade request, 15hr layover accommodation voucher guidance…so net in net avoid booking through three layers of intermediaries

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

Delayed for mechanical and no updates on what was happening and how long the delay might be.

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports