MYR - SFO

$185 Find Cheap Flights from Myrtle Beach to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$359
Overall average: $453
Delta
Tue 3/24Tue 3/31
MYR - SFO • 1 stop
Cheapest one-way
$185
Typical prices: $293-$452
Multiple Airlines
Sun 3/8
MYR - SFO • 2 stops
Top airlines
Delta
Cheapest • from $359 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
April
Cheapest • 21% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Francisco (MYR-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Francisco

Tue, Mar 24 - Tue, Mar 31
Delta Logo
1:01 pm - 7:07 pm
MYR
-
SFO
9h 06m
1 stop
Delta Logo
2:20 pm - 12:04 am
SFO
-
MYR
6h 44m
1 stop
$359Delta
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
6:01 am - 2:34 pm
MYR
-
SFO
11h 33m
2 stops
American Airlines Logo
11:29 pm - 11:46 am
SFO
-
MYR
9h 17m
1 stop
$364American Airlines
Tue, Mar 24 - Tue, Mar 31
American Airlines Logo
10:26 am - 7:16 pm
MYR
-
SFO
11h 50m
2 stops
American Airlines Logo
6:00 am - 8:45 pm
SFO
-
MYR
11h 45m
2 stops
$370American Airlines
Tue, Apr 7 - Mon, Apr 13
Southwest Logo
4:05 pm - 8:55 pm
MYR
-
SFO
7h 50m
1 stop
Southwest Logo
9:15 pm - 10:35 am
SFO
-
MYR
10h 20m
1 stop
$374Southwest
Tue, Apr 7 - Mon, Apr 13
Southwest Logo
4:05 pm - 10:45 pm
MYR
-
SFO
9h 40m
2 stops
Southwest Logo
9:15 pm - 10:35 am
SFO
-
MYR
10h 20m
1 stop
$379Southwest
Tue, Apr 7 - Mon, Apr 13
Southwest Logo
4:05 pm - 10:45 pm
MYR
-
SFO
9h 40m
2 stops
Southwest Logo
7:15 pm - 10:35 am
SFO
-
MYR
12h 20m
2 stops
$384Southwest
Tue, Apr 28 - Wed, May 27
Multiple Airlines Logo
7:51 pm - 4:54 pm
MYR
-
SFO
24h 03m
2 stops
Multiple Airlines Logo
11:59 pm - 11:50 am
SFO
-
MYR
8h 51m
1 stop
$386Multiple Airlines
Thu, Mar 26 - Mon, Mar 30
American Airlines Logo
6:22 pm - 11:10 pm
MYR
-
SFO
7h 48m
1 stop
American Airlines Logo
11:29 pm - 11:21 am
SFO
-
MYR
8h 52m
1 stop
$389American Airlines
Thu, Mar 26 - Mon, Mar 30
American Airlines Logo
5:10 am - 12:17 pm
MYR
-
SFO
10h 07m
1 stop
American Airlines Logo
7:00 pm - 9:36 am
SFO
-
MYR
11h 36m
2 stops
$394American Airlines
Wed, Apr 29 - Wed, May 27
Multiple Airlines Logo
7:51 pm - 10:31 pm
MYR
-
SFO
29h 40m
2 stops
Multiple Airlines Logo
11:59 pm - 11:50 am
SFO
-
MYR
8h 51m
1 stop
$399Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Francisco flights

Get data-powered insights and trends into flights from Myrtle Beach to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Francisco is April, where tickets cost $372 (return) on average. On the other hand, the most expensive months are November and December, where the average cost of round-trip tickets is $691 and $667 respectively.

Good to know

Low seasonNovember
Cheapest flight$132
Best time to beat the crowds but there is an average 46% increase in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Myrtle Beach to San Francisco

When to book flights from Myrtle Beach to San Francisco

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Francisco

  • What is the cheapest flight from Myrtle Beach to San Francisco?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Francisco was $185 for a one-way ticket and $359 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Francisco?

    No

  • Which airports will I be using when flying from Myrtle Beach to San Francisco?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Francisco is San Francisco.

  • Which aircraft models fly most regularly from Myrtle Beach to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Francisco?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Francisco, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Francisco, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Francisco are Delta and American Airlines. With an average price for the route of $406 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $427 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8206 reviews
7.8Entertainment
7.9Comfort
8.1Boarding
8.5Crew
7.2Food
Airline reviews

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

10.0 ExcellentSoosnata, Feb 2026
MIA - LAX
Read more Delta reviews

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Awful - both legs. The check in was awful, getting on the plane required walking down a spiral staircase (dangerous), then taking a bus about 5 miles out from the terminal. The seat was broken (I was in business), there was no internet during the flight (both legs). The aircraft was very old. I saw rust in some place, tape holding things up in the bathroom. This was an unacceptable experience for such a long haul flight.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Everything you need to know for your flight from Myrtle Beach to San Francisco

Information on your arrival and departure airports