MYR - SDQ

$457 Find Cheap Flights from Myrtle Beach to Santo Domingo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$457
Frontier
Tue 7/7Fri 7/10
MYR - SDQ • 1 stop
Top airlines
Frontier
Cheapest • from $457 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Orlando (MCO)
Cheapest • Avg $434 (round-trip)
Orlando (MCO)
Shortest trip • 5h 11m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Santo Domingo (MYR-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Santo Domingo

Tue, Jul 7 - Fri, Jul 10
Frontier Logo
6:28 pm - 11:03 am
MYR
-
SDQ
16h 35m
1 stop
Frontier Logo
12:18 pm - 11:43 am
SDQ
-
MYR
23h 25m
1 stop
$457Frontier
Sat, May 9 - Wed, May 13
Multiple Airlines Logo
6:30 am - 2:39 pm
MYR
-
SDQ
8h 09m
1 stop
Multiple Airlines Logo
12:41 pm - 8:36 pm
SDQ
-
MYR
31h 55m
2 stops
$464Multiple Airlines
Sat, Jul 4 - Sat, Jul 11
Multiple Airlines Logo
7:00 am - 4:48 pm
MYR
-
SDQ
9h 48m
1 stop
Multiple Airlines Logo
1:57 pm - 8:11 pm
SDQ
-
MYR
6h 14m
1 stop
$485Multiple Airlines
Sat, Jul 4 - Thu, Jul 9
Multiple Airlines Logo
7:00 am - 4:48 pm
MYR
-
SDQ
9h 48m
1 stop
Multiple Airlines Logo
1:57 pm - 9:50 am
SDQ
-
MYR
19h 53m
1 stop
$488Multiple Airlines
Sat, Jul 4 - Sat, Jul 11
Multiple Airlines Logo
3:43 pm - 7:18 pm
MYR
-
SDQ
27h 35m
2 stops
Multiple Airlines Logo
1:57 pm - 8:11 pm
SDQ
-
MYR
6h 14m
1 stop
$497Multiple Airlines
Sat, Jul 4 - Thu, Jul 9
Multiple Airlines Logo
3:43 pm - 7:18 pm
MYR
-
SDQ
27h 35m
2 stops
Multiple Airlines Logo
1:57 pm - 9:50 am
SDQ
-
MYR
19h 53m
1 stop
$500Multiple Airlines
Tue, Jul 7 - Sat, Jul 11
Multiple Airlines Logo
5:59 pm - 5:29 am
MYR
-
SDQ
11h 30m
1 stop
Multiple Airlines Logo
1:57 pm - 8:11 pm
SDQ
-
MYR
6h 14m
1 stop
$506Multiple Airlines
Tue, Jul 7 - Thu, Jul 9
Multiple Airlines Logo
5:59 pm - 5:29 am
MYR
-
SDQ
11h 30m
1 stop
Multiple Airlines Logo
1:57 pm - 9:50 am
SDQ
-
MYR
19h 53m
1 stop
$509Multiple Airlines
Thu, Jul 9 - Sat, Jul 11
Multiple Airlines Logo
7:00 am - 4:48 pm
MYR
-
SDQ
9h 48m
1 stop
Multiple Airlines Logo
1:57 pm - 8:11 pm
SDQ
-
MYR
6h 14m
1 stop
$513Multiple Airlines
Tue, Jul 7 - Sat, Jul 11
Multiple Airlines Logo
10:20 am - 4:29 pm
MYR
-
SDQ
30h 09m
2 stops
Multiple Airlines Logo
1:57 pm - 8:11 pm
SDQ
-
MYR
6h 14m
1 stop
$524Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Santo Domingo flights

Get data-powered insights and trends into flights from Myrtle Beach to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Santo Domingo were found on Frontier ($457) and American Airlines ($610).

Find deals

Good to know

Cheapest flight$457
Flight from Myrtle Beach to Santo Domingo

When to book flights from Myrtle Beach to Santo Domingo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Santo Domingo

  • What is the cheapest flight from Myrtle Beach to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Santo Domingo was $457 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Santo Domingo?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Santo Domingo is Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Myrtle Beach to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Santo Domingo?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Santo Domingo.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8467 reviews
7.8Entertainment
8.1Boarding
8.5Crew
7.2Food
7.9Comfort
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Everything you need to know for your flight from Myrtle Beach to Santo Domingo

Information on your arrival and departure airports

Myrtle Beach (MYR)
Santo Domingo (SDQ)