MYR - SDQ

$194 Find Cheap Flights from Myrtle Beach to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
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Cheap Flights from Myrtle Beach to Santo Domingo (MYR-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Santo Domingo

Fri, Aug 15 - Tue, Aug 19
Spirit Airlines Logo
6:31 pm - 4:00 pmMYR-SDQ
21h 29m2 stops
Spirit Airlines Logo
5:05 pm - 7:45 pmSDQ-MYR
26h 40m2 stops
$357Spirit Airlines
Find Deal
Sun, Sep 28 - Wed, Oct 1
Spirit Airlines Logo
7:36 pm - 4:00 pmMYR-SDQ
20h 24m1 stop
Spirit Airlines Logo
5:05 pm - 8:06 pmSDQ-MYR
27h 01m1 stop
$359Spirit Airlines
Find Deal
Sat, Aug 16 - Tue, Aug 19
Spirit Airlines Logo
7:26 pm - 4:00 pmMYR-SDQ
20h 34m1 stop
Spirit Airlines Logo
5:05 pm - 8:09 pmSDQ-MYR
27h 04m1 stop
$366Spirit Airlines
Find Deal
Sat, Aug 16 - Tue, Aug 19
Spirit Airlines Logo
6:45 am - 11:56 amMYR-SDQ
5h 11m1 stop
Spirit Airlines Logo
5:05 pm - 7:45 pmSDQ-MYR
26h 40m2 stops
$368Spirit Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
Spirit Airlines Logo
6:45 am - 11:56 amMYR-SDQ
5h 11m1 stop
Spirit Airlines Logo
5:05 pm - 7:45 pmSDQ-MYR
26h 40m2 stops
$370Spirit Airlines
Find Deal
Fri, Aug 15 - Tue, Aug 19
Spirit Airlines Logo
7:26 pm - 4:00 pmMYR-SDQ
20h 34m1 stop
Spirit Airlines Logo
5:05 pm - 8:09 pmSDQ-MYR
27h 04m1 stop
$381Spirit Airlines
Find Deal
Sun, Sep 28 - Wed, Oct 1
Spirit Airlines Logo
5:20 pm - 4:00 pmMYR-SDQ
22h 40m2 stops
Spirit Airlines Logo
5:05 pm - 8:06 pmSDQ-MYR
27h 01m1 stop
$383Spirit Airlines
Find Deal
Sat, Aug 16 - Tue, Aug 19
Spirit Airlines Logo
6:31 pm - 4:00 pmMYR-SDQ
21h 29m2 stops
Spirit Airlines Logo
5:05 pm - 9:26 pmSDQ-MYR
28h 21m3 stops
$384Spirit Airlines
Find Deal
Fri, Aug 15 - Mon, Aug 18
 Logo
6:31 pm - 4:00 pmMYR-SDQ
21h 29m2 stops
 Logo
1:25 am - 8:09 pmSDQ-MYR
18h 44m3 stops
Sat, Aug 16 - Mon, Aug 18
 Logo
6:45 am - 11:56 amMYR-SDQ
5h 11m1 stop
 Logo
1:25 am - 8:09 pmSDQ-MYR
18h 44m3 stops
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Santo Domingo flights

Get data-powered insights and trends into flights from Myrtle Beach to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What is the most popular layover airport when flying from Myrtle Beach to Santo Domingo?

Percentage of 1-stop round-trip flights from Myrtle Beach to Santo Domingo chosen by KAYAK users via each layover airport in the last 12 months (only includes trips with the same layover airport on both legs).

Atlanta (ATL) is the top choice – 63% of KAYAK users who clicked on 1-stop flights from Myrtle Beach to Santo Domingo picked an itinerary connecting there.

What is the cheapest layover airport when flying from Myrtle Beach to Santo Domingo?

Average round-trip price for 1-stop flights from Myrtle Beach to Santo Domingo clicked by KAYAK users in the last 12 months (only includes trips with the same layover airport on both legs).

Flights via Fort Lauderdale (FLL) offer the most affordable fares, with an average round-trip price of $327.

Which layover airport offers the shortest total travel time from Myrtle Beach to Santo Domingo?

Shortest average total travel time for 1-stop one-way flights from Myrtle Beach to Santo Domingo via different layover airports, based on KAYAK user data from the last 12 months.

Consider flying via Orlando (MCO) for the shortest journey. The average one-way travel time for flights connecting there is 5h 29m.

Which layover airport has the quickest connection when flying from Myrtle Beach to Santo Domingo?

Average layover duration at different layover airports for 1-stop one-way flights from Myrtle Beach to Santo Domingo, based on KAYAK user data from the last 12 months.

If you prefer a quick connection, Fort Lauderdale (FLL) often has the shortest layovers from Myrtle Beach to Santo Domingo, with an average of 1h 35m.

Good to know

Low seasonFebruary
Cheapest flight$194
Best time to beat the crowds with an average 45% drop in price.
Most popular time to fly and prices are also 30% lower on average.
Flight from Myrtle Beach to Santo Domingo

When to book flights from Myrtle Beach to Santo Domingo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Santo Domingo

  • What is the cheapest flight from Myrtle Beach to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Santo Domingo was $194 for a one-way ticket and $357 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Santo Domingo?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Santo Domingo is Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Myrtle Beach to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
7.9Comfort
8.5Crew
7.3Food
8.2Boarding
7.9Entertainment
Airline reviews

Delayed and took off even later than the scheduled delay time

8.0 ExcellentAnonymous, Jul 2025DTW - SEA
Read more Delta reviews

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Only issue was with seating. The economy fare we purchased did say there was no guarantee the three people in our party would be seated together, and we were not. At the gate, the agent told us more specifically, the fare we purchased meant we would be seated in middle seats only. This should just be made more obvious.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Flight was canceled, and no effort was made to help with rebooking, no hotel vouchers, no car transportation and minimal food voucher and most places for food were closed by the time the voucher was given. Waited for 3 hours for bags. Simply the worst travel experience I have ever had

The flight was 3.5 hrs delayed. I was not notified prior to arriving to the airport via spirit app. or via boarding pass that I already had loaded on my phone. The agent that i saw at the counter didn’t mention anything about the delay either. I only saw the update after logging in to my email account.

The flight and boarding process was smooth. Wifi was unavailable and I prepaid for it. Have requested a refund

Had a issue with catching flight due to airline, was unable to board flight

Spirit is a very uncomfortable travel experience. It’s cheap but you are squeezed into the seats like canned meat.

Not great. Seats uncomfortable. Crew a little rude. Amenities like wifi and drinks way too expensive.

Late departure by 1:45min. No explanation why. During boarding inconsistent policing of their baggage rules. Before takeoff and lamdimg strange obsession with window shade and armrest positions. Don't know why they care. 15 min tarmac delay on arrival, they blamed airport congestion but we were the o lh flight waiting, it was clear it was due to poor staff planning (only one ground crew to receive airplanes and multiple arrivals) Got there but was rrally lame the whole trip.

The seat belt was lengthy enough that I did not need an extender. Courteous and helpful flight attendants.

We sat on the tarmac for an hour waiting for a gate to deplane.

Friendly employees, good seat, on time, Great flight. Pilot and attendants greeted passengers as we deplaned. However, I could not ever understand what the flight attendant was saying on the mic. It was too fast, and too loud.

Everything was fine, but there was no food or entertainment, so I didn’t know how to rate that.

Everything you need to know for your flight from Myrtle Beach to Santo Domingo

Information on your arrival and departure airports

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