MYR - SDQ

$270 Find Cheap Flights from Myrtle Beach to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$429
Multiple Airlines
Sat 2/21Sat 3/7
MYR - SDQ • 1 stop
Cheapest one-way
$270
Spirit Airlines
Wed 12/24
MYR - SDQ • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Santo Domingo (MYR-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Santo Domingo

Sat, Feb 21 - Sat, Mar 7
Multiple Airlines Logo
6:15 am - 5:25 am
MYR
-
SDQ
22h 10m1 stop
Multiple Airlines Logo
11:56 am - 8:50 am
SDQ
-
MYR
21h 54m1 stop
$429Multiple Airlines
Sat, Feb 21 - Sat, Mar 7
Multiple Airlines Logo
6:15 am - 5:25 am
MYR
-
SDQ
22h 10m1 stop
Multiple Airlines Logo
12:15 pm - 8:50 am
SDQ
-
MYR
21h 35m2 stops
$447Multiple Airlines
Sat, Feb 21 - Sat, Mar 7
American Airlines Logo
3:18 pm - 9:48 am
MYR
-
SDQ
17h 30m2 stops
American Airlines Logo
3:15 pm - 7:31 am
SDQ
-
MYR
17h 16m2 stops
$507American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Santo Domingo flights

Get data-powered insights and trends into flights from Myrtle Beach to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Myrtle Beach and Santo Domingo?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Myrtle Beach to Santo Domingo.

There is just one airline that flies from Myrtle Beach to Santo Domingo direct and that is Spirit Airlines. The best round-trip deal found from Spirit Airlines for the route is $327.

Find deals

Good to know

Cheapest flight$270
Flight from Myrtle Beach to Santo Domingo

When to book flights from Myrtle Beach to Santo Domingo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Santo Domingo

  • What is the cheapest flight from Myrtle Beach to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Santo Domingo was $270 for a one-way ticket and $429 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Santo Domingo?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Santo Domingo is Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Myrtle Beach to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8007 reviews
7.9Comfort
7.3Food
8.1Boarding
7.9Entertainment
8.5Crew
Airline reviews

None of the airplane features were available during the flight.

4.0 OkayAnonymous, Dec 2025
JFK - SDQ
Read more Delta reviews

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Everything you need to know for your flight from Myrtle Beach to Santo Domingo

Information on your arrival and departure airports

Myrtle Beach (MYR)
Santo Domingo (SDQ)