MYR - SDQ

$237 Find Cheap Flights from Myrtle Beach to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Santo Domingo departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$404
Multiple Airlines
Isnin 4/27Isnin 5/4
MYR - SDQ • 1 stop
Cheapest one-way
$237
Multiple Airlines
Jumaat 5/1
MYR - SDQ • 2 stops
Top airlines
Cheapest • from $593 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $434 (round-trip)
Shortest trip • 5h 11m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Santo Domingo (MYR-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Santo Domingo

Isnin, Apr 27 - Isnin, Mei 4
Multiple Airlines Logo
8:43 pm - 5:29 am
MYR
-
SDQ
8h 46m
1 stop
Multiple Airlines Logo
2:35 pm - 8:58 pm
SDQ
-
MYR
6h 23m
1 stop
$404Multiple Airlines
Khamis, Mei 28 - Selasa, Jun 2
Multiple Airlines Logo
4:15 pm - 5:29 am
MYR
-
SDQ
13h 14m
1 stop
Multiple Airlines Logo
6:10 am - 3:10 pm
SDQ
-
MYR
9h 00m
1 stop
$523Multiple Airlines
Selasa, Mei 26 - Ahad, Mei 31
Multiple Airlines Logo
4:15 pm - 5:29 am
MYR
-
SDQ
13h 14m
1 stop
Multiple Airlines Logo
3:30 pm - 2:20 pm
SDQ
-
MYR
22h 50m
2 stops
$531Multiple Airlines
Selasa, Mei 26 - Ahad, Mei 31
Multiple Airlines Logo
4:15 pm - 5:29 am
MYR
-
SDQ
13h 14m
1 stop
Multiple Airlines Logo
2:35 pm - 2:20 pm
SDQ
-
MYR
23h 45m
1 stop
$537Multiple Airlines
Khamis, Mei 28 - Selasa, Jun 2
Multiple Airlines Logo
3:53 pm - 1:29 pm
MYR
-
SDQ
21h 36m
2 stops
Multiple Airlines Logo
6:10 am - 3:10 pm
SDQ
-
MYR
9h 00m
1 stop
$545Multiple Airlines
Isnin, Apr 27 - Isnin, Mei 4
American Airlines Logo
5:00 am - 4:55 pm
MYR
-
SDQ
11h 55m
2 stops
American Airlines Logo
2:25 pm - 11:57 pm
SDQ
-
MYR
9h 32m
2 stops
$593American Airlines
Selasa, Mei 26 - Ahad, Mei 31
American Airlines Logo
1:01 pm - 10:55 pm
MYR
-
SDQ
9h 54m
2 stops
American Airlines Logo
7:35 pm - 3:58 pm
SDQ
-
MYR
20h 23m
2 stops
$598American Airlines
Khamis, Mei 7 - Isnin, Mei 11
American Airlines Logo
1:57 pm - 10:52 pm
MYR
-
SDQ
8h 55m
2 stops
American Airlines Logo
10:20 am - 11:57 pm
SDQ
-
MYR
13h 37m
2 stops
$603American Airlines
Isnin, Mei 25 - Sabtu, Mei 30
American Airlines Logo
8:41 pm - 3:18 pm
MYR
-
SDQ
18h 37m
2 stops
American Airlines Logo
7:35 pm - 1:51 pm
SDQ
-
MYR
18h 16m
2 stops
$613American Airlines
Isnin, Mei 25 - Sabtu, Mei 30
American Airlines Logo
6:45 pm - 12:45 pm
MYR
-
SDQ
18h 00m
1 stop
American Airlines Logo
7:35 pm - 12:35 pm
SDQ
-
MYR
17h 00m
2 stops
$632American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Santo Domingo flights

Get data-powered insights and trends into flights from Myrtle Beach to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Santo Domingo were found on American Airlines ($593) and Delta ($639).

Good to know

Cheapest flight$237
Flight from Myrtle Beach to Santo Domingo

When to book flights from Myrtle Beach to Santo Domingo

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Santo Domingo

  • What is the cheapest flight from Myrtle Beach to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Santo Domingo was $237 for a one-way ticket and $404 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Myrtle Beach.

  • Which airports will I be using when flying from Myrtle Beach to Santo Domingo?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Santo Domingo is Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Myrtle Beach to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Santo Domingo?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Santo Domingo.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8286 reviews
8.1Boarding
7.9Comfort
8.5Crew
7.2Food
7.8Entertainment
Airline reviews

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

2.0 MediocreAnonymous, Mar 2026
LAX - BNA
Read more Delta reviews

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

With Aeromexico it ended up good but with Delta it was bad because we did everything through Delta... Showed up at the Delta terminal... It was the wrong place! Nothing ever told us to go to the Aeromexico terminal. It said "in partnership with Aeromexico" but I was never instructed to check in with them or go to their terminal. We had to haul @$$ running through the airport and almost didn't make it thanks to this poor communication. 👎🏽

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

Everything you need to know for your flight from Myrtle Beach to Santo Domingo

Information on your arrival and departure airports