$106 Find Cheap Flights from Panama City to Missouri - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Missouri departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Panama City to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$362
Kansas City
Kansas City1 stop$211
Springfield
Springfield1 stop$291
St. Louis
St. Louis1 stop$362
Kansas City
Kansas City1 stop$211
Springfield
Springfield1 stop$291

Book Cheap Panama City to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Missouri

Thu, Sep 24 - Tue, Sep 29
American Airlines Logo
3:17 pm - 8:20 pm
ECP
-
MCI
5h 03m
1 stop
American Airlines Logo
9:49 am - 2:22 pm
MCI
-
ECP
4h 33m
1 stop
$211American Airlines
Wed, Aug 5 - Tue, Aug 11
Southwest Logo
7:45 am - 4:15 pm
ECP
-
MCI
8h 30m
2 stops
Southwest Logo
1:25 pm - 6:10 pm
MCI
-
ECP
4h 45m
1 stop
$235Southwest
Wed, Aug 5 - Tue, Aug 11
Southwest Logo
7:45 am - 4:15 pm
ECP
-
MCI
8h 30m
2 stops
Southwest Logo
11:55 am - 6:10 pm
MCI
-
ECP
6h 15m
2 stops
$258Southwest
Sun, Aug 23 - Sat, Aug 29
Delta Logo
7:35 am - 12:26 pm
ECP
-
MCI
4h 51m
1 stop
Delta Logo
6:00 am - 12:42 pm
MCI
-
ECP
6h 42m
1 stop
$265Delta
Thu, Sep 17 - Sun, Sep 20
Southwest Logo
6:00 am - 11:05 am
ECP
-
MCI
5h 05m
1 stop
Southwest Logo
1:15 pm - 3:20 pm
MCI
-
ECP
2h 05mnonstop
$270Southwest
Thu, Sep 17 - Sun, Sep 20
Southwest Logo
4:10 pm - 11:15 pm
ECP
-
MCI
7h 05m
2 stops
Southwest Logo
2:35 pm - 9:50 pm
MCI
-
ECP
7h 15m
1 stop
$289Southwest
Tue, Nov 10 - Sat, Nov 14
Delta Logo
9:23 am - 2:50 pm
ECP
-
SGF
5h 27m
1 stop
Delta Logo
6:00 am - 12:39 pm
SGF
-
ECP
6h 39m
1 stop
$291Delta
Tue, Dec 8 - Wed, Dec 9
United Airlines Logo
10:25 am - 5:19 pm
ECP
-
MCI
6h 54m
1 stop
United Airlines Logo
6:10 am - 12:37 pm
MCI
-
ECP
6h 27m
1 stop
$291United Airlines
Tue, Dec 8 - Wed, Dec 9
United Airlines Logo
6:30 am - 4:03 pm
ECP
-
MCI
9h 33m
2 stops
United Airlines Logo
6:10 am - 12:37 pm
MCI
-
ECP
6h 27m
1 stop
$296United Airlines
Wed, Aug 5 - Tue, Aug 11
American Airlines Logo
7:32 am - 12:43 pm
ECP
-
SGF
5h 11m
1 stop
American Airlines Logo
3:01 pm - 10:40 pm
SGF
-
ECP
7h 39m
1 stop
$373American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Missouri flights

Get data-powered insights and trends into flights from Panama City to Missouri to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to Missouri?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to Missouri departing in September.

What is the cheapest Panama City to Missouri flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Missouri from Panama City found in the last 5 days was to St. Louis, at $345 round-trip. The most popular route is from Panama City (ECP) to St. Louis (STL), and the cheapest round-trip airline ticket found on this route in the last 5 days was $345.

Can I save money by flying with a layover from Panama City to Missouri?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $463 on average.

What is the cheapest month to fly from Panama City to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Missouri is August, when tickets cost $157 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $287 and $286 respectively.

Good to know

Low seasonDecember
Cheapest flight$106
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to Kansas City

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Panama City to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Missouri

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: Kansas City $267 one-way - $497 round-trip; St. Louis $231 one-way - $376 round-trip

Reviews of the top 3 airlines serving from Panama City to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4249 reviews
7.5Entertainment
8.1Boarding
8.0Comfort
8.6Crew
7.0Food
Airline reviews

Great job! My family doesnt fly often but we felt safe 100%

10.0 ExcellentK, Jun 2026
AUS - MCI
Read more Southwest reviews

Great job! My family doesnt fly often but we felt safe 100%

Communication about the delayed flight was poor. We were told to move gates three times but that was bad information. We went from gate 128 to gate 126 and then to gate 123 and back to gate 126. Communication about the delay was bad. Ended up being 1 1/2 hour late getting home.

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

Everything went smoothly and we even arrived a little bit early.

Boarded on time but once we were ready for take off, the crew determined that, although every seat was taken, somehow someone was on the wrong flight. Delay, delay delay, announcements and ended up with one person checking EVERY ID against their passenger Manifest only to figure out it was a "clerical error." We departed 54 minutes late causing me to run in the St. Louis Airport to make my connection and lose the priority boarding spot I had paid for. Unnecessary delay.

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

Crew always seems to be unprofessional no matter what Southwest flight I fly

Southwest is definitely the happiest airline to fly with. They are always kind and friendly with a sense of humor.

Noticed the width between seats seemed less. I wasn’t very comfortable. I’m of regular weight btw. We got graham cracker cookie snack, no choices. The bathrooms toilet roll was broken, and the light wouldn’t come on when I tried to close bathroom door.. I wasn’t sure it was locked?

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

Five hour delays every hour, I wish it were all at once

Planes were clean, no water or snacks on either flight.

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

On 2 different flights the wifi was horrible and there was no drink or snack service.

There was no FREE wi-fi nor entertainment screens at all.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

As we lined up to board they gave our plane to a flight going to Newark. So then we got delayed until they could find another plane. Flight crew was ok. I’m assuming since it’s a shorter flight they only offered water and coffee.

Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Improvements in communication and empathy are absolutely necessary for American Airlines staff (top down). It’s like they are numb to the needs of their customers.

I had a TERRIBLE experience with the AA crew. I believe it was disability-related. It’s unlikely I will fly AA again.

I like the speed of boarding and deplaning and the fact that everything was on time. The crew (attendants) were probably quite new and did not begin the in cabin service until 30 min before landing even though there was little to no air turbulence for the last 1.5 hours of the flight. It made for a mad scramble at the end to get trash collected and carts stowed before touch down.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

Everything you need to know for your flight from Panama City to Missouri

Information on your arrival and departure airports