$104 Find Cheap Flights from Panama City to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Missouri departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$207
Kansas City
Kansas City1 stop$271
Springfield
Springfield1 stop$368
St. Louis
St. Louis1 stop$207
Kansas City
Kansas City1 stop$271
Springfield
Springfield1 stop$368

Book Cheap Panama City to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Missouri

Fri, Dec 5 - Sun, Dec 7
Delta Logo
6:49 pm - 11:40 pmECP-STL
4h 51m1 stop
Delta Logo
7:02 pm - 10:58 pmSTL-ECP
3h 56m1 stop
$207Delta
Find Deal
Fri, Dec 5 - Sun, Dec 7
American Airlines Logo
12:55 pm - 7:29 pmECP-STL
6h 34m1 stop
American Airlines Logo
5:15 am - 2:13 pmSTL-ECP
8h 58m2 stops
$212American Airlines
Find Deal
Fri, Oct 24 - Mon, Oct 27
Southwest Logo
7:20 pm - 10:55 pmECP-STL
3h 35m1 stop
Southwest Logo
8:35 am - 10:20 amSTL-ECP
1h 45mnonstop
$217Southwest
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Fri, Oct 24 - Mon, Oct 27
Delta Logo
6:17 pm - 11:41 pmECP-STL
5h 24m1 stop
Delta Logo
7:05 am - 12:30 pmSTL-ECP
5h 25m1 stop
$227Delta
Find Deal
Fri, Oct 24 - Mon, Oct 27
American Airlines Logo
3:41 pm - 11:54 pmECP-STL
8h 13m2 stops
American Airlines Logo
5:30 am - 10:13 amSTL-ECP
4h 43m1 stop
$232American Airlines
Find Deal
Thu, Oct 30 - Sun, Nov 2
American Airlines Logo
6:44 am - 4:03 pmECP-STL
9h 19m2 stops
American Airlines Logo
6:45 pm - 11:49 pmSTL-ECP
5h 04m1 stop
$264American Airlines
Find Deal
Sat, Feb 14 - Sat, Feb 21
Delta Logo
5:00 pm - 12:01 amECP-MCI
7h 01m1 stop
Delta Logo
12:30 pm - 6:38 pmMCI-ECP
6h 08m1 stop
$271Delta
Find Deal
Mon, Oct 27 - Sat, Nov 8
Southwest Logo
7:30 pm - 12:10 amECP-MCI
4h 40m1 stop
Southwest Logo
5:30 am - 11:25 amMCI-ECP
5h 55m1 stop
$330Southwest
Find Deal
Mon, Oct 13 - Fri, Oct 17
United Airlines Logo
5:08 pm - 9:59 pmECP-SGF
4h 51m1 stop
United Airlines Logo
6:30 pm - 1:51 pmSGF-ECP
19h 21m2 stops
$852United Airlines
Find Deal
Mon, Oct 13 - Fri, Oct 17
United Airlines Logo
6:30 am - 6:24 pmECP-SGF
11h 54m1 stop
United Airlines Logo
3:11 pm - 1:51 pmSGF-ECP
22h 40m2 stops
$906United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to Missouri flights

Get data-powered insights and trends into flights from Panama City to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Panama City to Missouri flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Missouri from Panama City found in the last 72 hours was to St. Louis, at $197 round-trip. The most popular route is from Panama City (ECP) to St. Louis (STL), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $197.

Can I save money by flying with a layover from Panama City to Missouri?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $309, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Missouri is August, when tickets cost $246 (return) on average. On the other hand, the most expensive months are February and January, when the average cost of round-trip tickets is $808 and $504 respectively.

Good to know

Low seasonFebruary
Cheapest flight$104
Best time to beat the crowds but there is an average 31% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Panama City to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Missouri

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: St. Louis $203 one-way - $388 round-trip

Reviews of the top 4 airlines serving from Panama City to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4248 reviews
8.0Comfort
8.6Crew
7.0Food
7.5Entertainment
8.1Boarding
Airline reviews

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

6.0 GoodDavid, Aug 2025MCO - DEN
Read more Southwest reviews

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

It was one and half hour late... Not sure if any other experience matters.

For my birthday trip this was my second time ever flying, this trip was the best.

Everything was on time. I was disappointed by the front section female, African American flight attendant. I did not see her name tag or would have identified by name not race. As passengers moved to the bathroom early in flight, she would say with a disdainful tone “I have to say the seat belt light is on” then go back to her book. Better trained flight attendants say something like be careful the seat belt light is on.

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

WiFi on the flight was not working. Thus, entertainment options were limited.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

It is clear that someone knew, and competent, is in charge of food at United Airlines at least for the international flights. I was flying in coach, but the choices of the dinner were excellent. Tasty, and appropriate size. I had the beef, which was a little bit like a shepherds pie, and it was good. Nothing comparable has been served on a United flight in years. It will not be confused with three star food, but it is very good for airline food. Even better was the breakfast choice between a cinnamon roll and a breakfast sandwich. I chose the breakfast sandwich which was absolutely delicious and which I would happily order again at my local Starbucks or Panera. It is clear that someone knew indifferent is in charge of the food and it’s about time.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Staff members were not helpful they ignored all calls for an attendant.

Terrible. Delayed 7 hours, and cancelled the flight, leaving me stranded and out of pocket $500 for an alternative last minute flight

online check in was not available so i had to get to airport extra early. The flight was delayed and my luggage was lost. I had an argument with the person behind me who wanted to keep her bag on the floor and not allow my seat to recline on a 9hr plus flight. So overall, lots and lots of areas for improvement.

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

Multiple delays and not straight answer from the United team

Food and flight attendents with positive dispositions and friendly behavior, more professional attitudes

We paid extra for the seats with extra leg room. But we were not allocated the seats with extra leg room nor refunded the money we paid for the seats.

Lost bag and 2 days no word leaving for cruise no clothes or stuff

We will be writing a long, detailed letter to corporate about our awful experience with American airlines.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Food was ok, but not as good as I have had before on AA.

Pretty good. The food was just mediocre, the boarding and crew were good.

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

I was late from Jacksonville, FL but the limited interaction I had with the Philly crew was great.

The delays and cancellations kept me stuck in Miami for an additional 24 hours, and the whole thing seemed extremely disorganized

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Everything you need to know for your flight from Panama City to Missouri

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