$101 Find Cheap Flights from Panama City to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Missouri departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
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Flights Deals

Best Missouri Flight Deals from Panama City

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$221
Kansas City
Kansas City1 stop$227
Springfield
Springfield1 stop$259
St. Louis
St. Louis1 stop$221
Kansas City
Kansas City1 stop$227
Springfield
Springfield1 stop$259

Cheap Flights from Panama City to Missouri (ECP-USMO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Missouri

Thu, Jun 5 - Mon, Jun 9
Delta Logo
6:59 pm - 11:38 pmECP-STL
4h 39m1 stop
Delta Logo
5:30 pm - 11:21 pmSTL-ECP
5h 51m1 stop
$221Delta
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Mon, Jul 21 - Wed, Jul 30
Delta Logo
7:38 pm - 11:59 pmECP-MCI
4h 21m1 stop
Delta Logo
7:00 am - 12:19 pmMCI-ECP
5h 19m1 stop
$227Delta
Find Deal
Thu, Jun 12 - Thu, Jun 19
American Airlines Logo
7:02 pm - 11:59 pmECP-STL
4h 57m1 stop
American Airlines Logo
4:37 pm - 11:49 pmSTL-ECP
7h 12m1 stop
$241American Airlines
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Tue, Jul 1 - Thu, Jul 3
American Airlines Logo
3:55 pm - 8:54 pmECP-STL
4h 59m1 stop
American Airlines Logo
4:37 pm - 11:49 pmSTL-ECP
7h 12m1 stop
$254American Airlines
Find Deal
Tue, Jul 1 - Thu, Jul 3
Southwest Logo
6:05 am - 7:55 amECP-STL
1h 50mnonstop
Southwest Logo
7:30 am - 9:15 amSTL-ECP
1h 45mnonstop
$256Southwest
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Thu, May 29 - Mon, Jun 2
United Airlines Logo
3:20 pm - 10:00 pmECP-SGF
6h 40m1 stop
United Airlines Logo
3:00 pm - 10:00 pmSGF-ECP
7h 00m1 stop
$259United Airlines
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Tue, Jul 1 - Thu, Jul 3
American Airlines Logo
12:33 pm - 8:30 pmECP-STL
7h 57m2 stops
American Airlines Logo
4:37 pm - 11:49 pmSTL-ECP
7h 12m1 stop
$259American Airlines
Find Deal
Fri, Jul 25 - Thu, Jul 31
Delta Logo
6:00 am - 12:03 pmECP-MCI
6h 03m1 stop
Delta Logo
6:33 pm - 11:21 pmMCI-ECP
4h 48m1 stop
$267Delta
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Tue, Jul 1 - Thu, Jul 3
Southwest Logo
6:05 am - 7:55 amECP-STL
1h 50mnonstop
Southwest Logo
4:40 pm - 10:15 pmSTL-ECP
5h 35m1 stop
$280Southwest
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Thu, Sep 18 - Sun, Sep 21
United Airlines Logo
5:06 pm - 10:26 pmECP-MCI
5h 20m1 stop
United Airlines Logo
7:30 am - 1:05 pmMCI-ECP
5h 35m1 stop
$360United Airlines
Find Deal
Useful Info

KAYAK's insights & trends for Panama City to Missouri flights

Get data-powered insights and trends into flights from Panama City to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Panama City to Missouri flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Panama City to Missouri.

The cheapest ticket to Missouri from Panama City found in the last 72 hours was to Kansas City, at $207 round-trip. The most popular route is from Panama City (ECP) to St. Louis (STL), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $295.

Can I save money by flying with a layover from Panama City to Missouri?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $451, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Missouri is July, when tickets cost $344 (return) on average. On the other hand, the most expensive months are February and October, when the average cost of round-trip tickets is $808 and $648 respectively.


Good to know

Low seasonFebruary
High seasonJuly
Cheapest flight$101
Best time to beat the crowds but there is an average 27% increase in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Panama City to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Panama City to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Missouri

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: St. Louis $194 one-way - $369 round-trip

Top 4 airlines serving from Panama City to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4289 reviews
8.6Crew
8.0Comfort
7.1Food
8.2Boarding
7.6Entertainment
Airline reviews

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

6.0 GoodAnonymous, May 2025HOU - MCI
Read more Southwest reviews

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

WiFi on the flight was not working. Thus, entertainment options were limited.

Flight was awfully bumpy and landing was a bit jolting. I was in the restroom when snacks and drinks were served and was not asked if i wanted any. I had to ask for water finally.

It was 2 hours 45 minutes late, for no apparently clear reason.

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

Everything was great except the food. The pretzels are really crappy.

Planes are aged. The wifi is unreliable and on many fights, no-existent. The flight attendants were very good.

I had a wonderful flight, but the only thing that annoyed me was how crowded TSA was. I still believe airports and all planes work together to bunch everyone together to drive up cost.

Easy to book and to get check in and get on and off.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The young man who was our flight attendant in first class was lazy and did not do his job well at all. Never offered drinks upon boarding - actually I take that back... said "are you okay with water" as if I do not want to get you anything else, only passed the snacks around once, got my drink order wrong and then never offered a second round of drinks. He was the worst I have ever seen on Delta and we fly a lot.

Flight left early and arrived early. the whole trip was excellent.

Newer plane, relatively easy boarding, not a full flight and was told that we could not be moved up because of weight and balance issues. Otherwise, a very good experience.

Everything was great. Great service, excellent communication, and early arrival

I sat in comfort plus. It was fine. Seats were comfortable. I got drinks and snacks.

Good and consistent Printer in lounge did not work for me :(

Great - This was the last flight before hurricane closures and did a quick turnaround to get the plane heading north. Much appreciated.

The schedule to Moline changed 5 times. The gate changed 6 times. That is a pathetic way to run an airline. No wonder that no one in our company flies on United Express to or from Moline. Changes happen most of the time. I learned my lesson on this trip…never again!

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

Multiple delays and not straight answer from the United team

Food and flight attendents with positive dispositions and friendly behavior, more professional attitudes

We paid extra for the seats with extra leg room. But we were not allocated the seats with extra leg room nor refunded the money we paid for the seats.

I liked all the informational texts. I always knew where to go and when .

Liked the hospitality . The ight took us 6 hrs to get from fort myers to ewr.

Flight was delayed two hours. No snacks and no tv screens. My bag got stuck in Chicago

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Crew professional. Easy bag drop off. On time. Good entertainment.

Flight was late and missed connecting flight. They could have better accommodated, but instead did an overnight and had to arrive the next afternoon.

The boarding crew was incredibly helpful getting me on an earlier flight

They have lost any customer service care and support. Terrible airline now and been for awhile.

The flight was delayed leaving Miami. When we arrived in Charlotte, we were unable to park at our scheduled gate. We had to wait another 30-45 minutes before we could park at a different gate. All in all, we were delayed by almost two hours arriving in Charlotte.

the pilot that landed this flight in Philadelphia did an amazing job, the weather was absolutely terrible and we landed safely.

Per usual, flight status, staff courtesy and professionalism were excellent

The seats were crammed and the guy in front of me wouldn't stop reclining. If AA is cramming extra rows in, they need to take away the reclining in coach. My knees were smashed for 4 1/2 hours and I was very close to confronting the passenger in front of me.

AA can't control the weather. But the airplane was hot and stuffy while stuck on the runway with a broken entertainment system.

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