ECP - STL

$145 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$289
Typical prices: $441-$808
Delta
Sat 2/14Wed 2/18
ECP - STL • 1 stop
Cheapest non-stop
$480
Southwest
Fri 5/15Fri 5/22
ECP - STL • Non-stop
When to travel
October
Cheapest • 50% price drop
November
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (ECP-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Sat, Feb 14 - Wed, Feb 18
Delta Logo
2:05 pm - 7:56 pm
ECP
-
STL
5h 51m1 stop
Delta Logo
7:10 am - 1:20 pm
STL
-
ECP
6h 10m1 stop
$289Delta
Sat, Feb 14 - Mon, Feb 16
United Airlines Logo
6:30 am - 4:02 pm
ECP
-
STL
9h 32m2 stops
United Airlines Logo
6:00 am - 12:04 pm
STL
-
ECP
6h 04m1 stop
$294United Airlines
Sat, Feb 14 - Tue, Feb 17
United Airlines Logo
6:30 am - 4:02 pm
ECP
-
STL
9h 32m2 stops
United Airlines Logo
11:25 am - 7:51 pm
STL
-
ECP
8h 26m2 stops
$300United Airlines
Wed, Feb 11 - Thu, Feb 19
Delta Logo
6:00 am - 11:54 am
ECP
-
STL
5h 54m1 stop
Delta Logo
6:47 pm - 10:39 pm
STL
-
ECP
3h 52m1 stop
$314Delta
Sat, Feb 14 - Sat, Feb 14
Delta Logo
6:00 am - 11:02 am
ECP
-
STL
5h 02m1 stop
Delta Logo
5:01 pm - 10:39 pm
STL
-
ECP
5h 38m1 stop
$337Delta
Tue, Feb 17 - Thu, Feb 19
Delta Logo
6:00 am - 11:02 am
ECP
-
STL
5h 02m1 stop
Delta Logo
6:47 pm - 10:39 pm
STL
-
ECP
3h 52m1 stop
$339Delta
Sun, Jan 18 - Wed, Jan 21
Delta Logo
7:20 am - 11:05 am
ECP
-
STL
3h 45m1 stop
Delta Logo
6:00 am - 11:08 am
STL
-
ECP
5h 08m1 stop
$355Delta
Sun, May 17 - Mon, May 25
Delta Logo
1:30 pm - 6:02 pm
ECP
-
STL
4h 32m1 stop
Delta Logo
7:20 am - 1:55 pm
STL
-
ECP
6h 35m1 stop
$357Delta
Sun, Feb 15 - Mon, Feb 16
American Airlines Logo
1:19 pm - 9:37 pm
ECP
-
STL
8h 18m1 stop
American Airlines Logo
4:13 pm - 9:22 pm
STL
-
ECP
5h 09m1 stop
$359American Airlines
Wed, Feb 11 - Tue, Feb 17
United Airlines Logo
6:30 am - 5:18 pm
ECP
-
STL
10h 48m2 stops
United Airlines Logo
6:00 am - 12:04 pm
STL
-
ECP
6h 04m1 stop
$364United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is October, where tickets cost $197 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $786 and $533 respectively.

Can I save money by flying with a layover from Panama City to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $262 on average.

Good to know

Low seasonJanuary
Cheapest flight$145
Best time to beat the crowds but there is an average 36% increase in price.
Most popular time to fly and prices are also 26% lower on average.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $145 for a one-way ticket and $289 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Panama City to St. Louis?

    When flying out of Panama City you will be using Panama City NW Florida Beaches. You will be landing at St. Louis, also known as Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to St. Louis?

    American Airlines, and Delta offer inflight Wi-Fi service on the Panama City to St. Louis flight route.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    The Embraer 175 (Enhanced Winglets) is the aircraft model that flies most regularly on the Panama City to St. Louis flight route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    SkyTeam is the only airline alliance operating flights between Panama City and St. Louis.

  • Which is the best airline for flights from Panama City to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Panama City to St. Louis are Southwest and Delta. With an average price for the route of $390 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $345 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $497 or less round-trip.

Prefer to fly direct from Panama City to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City NW Florida Beaches to Lambert-St Louis.
Find which airlines fly direct from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Panama City NW Florida Beaches to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Panama City NW Florida Beaches

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airlines flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4252 reviews
7.5Entertainment
8.0Comfort
7.0Food
8.1Boarding
8.6Crew
Airline reviews

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

8.0 ExcellentChad, Dec 2025
PNS - BNA
Read more Southwest reviews

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Boarded on time but once we were ready for take off, the crew determined that, although every seat was taken, somehow someone was on the wrong flight. Delay, delay delay, announcements and ended up with one person checking EVERY ID against their passenger Manifest only to figure out it was a "clerical error." We departed 54 minutes late causing me to run in the St. Louis Airport to make my connection and lose the priority boarding spot I had paid for. Unnecessary delay.

Flight was delayed due to plane not passing inspection And one of the crew had to time out and we had to wait for another one A 3 hour delay

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

It was one and half hour late... Not sure if any other experience matters.

For my birthday trip this was my second time ever flying, this trip was the best.

Everything was on time. I was disappointed by the front section female, African American flight attendant. I did not see her name tag or would have identified by name not race. As passengers moved to the bathroom early in flight, she would say with a disdainful tone “I have to say the seat belt light is on” then go back to her book. Better trained flight attendants say something like be careful the seat belt light is on.

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports