$114 Find Cheap Flights from Panama City to St. Louis - Compare and Save

These are the earliest and latest flight times available from Panama City to St. Louis:

• Earliest: departs at 5:55 am and lands at 7:46 am
• Latest: departs at 7:10 pm and lands at 9:01 pm.

The flight takes about 1h 51m.

Two cabin classes are available on flights from Panama City to St. Louis:

• Economy Class
• First Class

A nonstop flight from Panama City to St. Louis takes 1h 51m, covering 635 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from Panama City to St. Louis range from $294 to $434, with an average of $368 over the past 12 months. Anything below $294 counts as a good deal.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $326 round-trip via Nashville Intl (BNA), compared to $364 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$91 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737-800 Passenger/BBJ2 (winglets) family is used most often on this route, operated mainly by Southwest. Other aircraft seen on the route include Canadair (Bombardier) Regional Jet 900 variants.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $227 to $1,069. That means the highest observed fare was about 5x higher than the lowest one.

One-way fares from Panama City to St. Louis are currently lower than usual. Average one-way flight prices are about $128, which is 46% below the typical average for this route.

Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:

• Hertz
• Budget
• Alamo
• Enterprise Rent-A-Car
• Payless

Flights from Panama City to St. Louis usually depart from Panama City NW Florida Beaches (ECP) and arrive at Lambert-St Louis (STL).

One-stop flights from Panama City to St. Louis most commonly connect through:

• Atlanta Hartsfield-Jackson (ATL) - 80% of one-stop connections
• Nashville Intl (BNA) - 13% of one-stop connections
• Charlotte Douglas (CLT) - 3% of one-stop connections
• Dallas/Fort Worth (DFW) - 3% of one-stop connections

Yes. Flexible dates can save you up to 44% on flights from Panama City to St. Louis. Saturday is the cheapest departure day at $253 round-trip on average, while Sunday is the most expensive at $444, a difference of $191.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

Only Southwest operates flights between Panama City and St. Louis.

Flying via Nashville Intl (BNA) gives the shortest average 1-stop total travel time at 3h 53m, compared with 4h 16m via Atlanta Hartsfield-Jackson (ATL) and 5h 25m via Charlotte Douglas (CLT).

Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Among airlines operating Panama City to St. Louis flights:

• Southwest: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Southwest: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.