ECP - STL

$158 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$315
Typical prices: $362-$243
Delta
Wed 7/29Thu 8/6
ECP - STL • 1 stop
Cheapest non-stop
$351
Southwest
Fri 6/5Tue 6/9
ECP - STL • Non-stop
Top airlines
Cheapest • from $315 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Southwest. Average duration is 1h 53m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top layover airports
Cheapest • Avg $289 (round-trip)
Shortest trip • 3h 48m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 41% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (ECP-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Wed, Jul 29 - Thu, Aug 6
Delta Logo
9:15 am - 2:35 pm
ECP
-
STL
5h 20m
1 stop
Delta Logo
3:40 pm - 8:46 pm
STL
-
ECP
5h 06m
1 stop
$315Delta
Fri, Apr 24 - Sun, Apr 26
Southwest Logo
5:00 pm - 10:45 pm
ECP
-
STL
5h 45m
1 stop
Southwest Logo
1:15 pm - 5:30 pm
STL
-
ECP
4h 15m
1 stop
$317Southwest
Fri, Jun 5 - Tue, Jun 9
Southwest Logo
6:20 pm - 12:05 am
ECP
-
STL
5h 45m
1 stop
Southwest Logo
12:40 pm - 7:40 pm
STL
-
ECP
7h 00m
2 stops
$320Southwest
Fri, Apr 24 - Sun, Apr 26
Southwest Logo
11:30 am - 6:55 pm
ECP
-
STL
7h 25m
1 stop
Southwest Logo
5:25 am - 1:15 pm
STL
-
ECP
7h 50m
2 stops
$322Southwest
Thu, Apr 23 - Tue, Apr 28
Southwest Logo
7:10 am - 2:55 pm
ECP
-
STL
7h 45m
2 stops
Southwest Logo
5:35 am - 1:20 pm
STL
-
ECP
7h 45m
2 stops
$327Southwest
Fri, Jun 5 - Tue, Jun 9
Southwest Logo
6:20 pm - 12:05 am
ECP
-
STL
5h 45m
1 stop
Southwest Logo
7:25 pm - 9:10 pm
STL
-
ECP
1h 45mnonstop
$330Southwest
Thu, Apr 23 - Tue, Apr 28
Southwest Logo
4:10 pm - 10:40 pm
ECP
-
STL
6h 30m
1 stop
Southwest Logo
6:40 pm - 8:25 pm
STL
-
ECP
1h 45mnonstop
$331Southwest
Fri, Apr 24 - Sun, Apr 26
Southwest Logo
11:30 am - 10:40 pm
ECP
-
STL
11h 10m
2 stops
Southwest Logo
5:25 am - 1:15 pm
STL
-
ECP
7h 50m
2 stops
$333Southwest
Tue, Apr 28 - Mon, May 4
Southwest Logo
10:10 am - 6:00 pm
ECP
-
STL
7h 50m
1 stop
Southwest Logo
7:20 am - 11:35 am
STL
-
ECP
4h 15m
1 stop
$334Southwest
Fri, Jul 17 - Sun, Jul 26
Delta Logo
6:41 pm - 11:53 pm
ECP
-
STL
5h 12m
1 stop
Delta Logo
6:00 am - 12:31 pm
STL
-
ECP
6h 31m
1 stop
$335Delta
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to St. Louis departing in July.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is October, where tickets cost $198 (return) on average. On the other hand, the most expensive months are April and June, where the average cost of round-trip tickets is $499 and $410 respectively.

Can I save money by flying with a layover from Panama City to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $350 on average.

Good to know

Low seasonDecember
Cheapest flight$158
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $158 for a one-way ticket and $315 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Panama City to St. Louis?

    When flying out of Panama City you will be using Panama City NW Florida Beaches. You will be landing at St. Louis, also known as Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to St. Louis?

    American Airlines, and Delta offer inflight Wi-Fi service on the Panama City to St. Louis flight route.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Panama City to St. Louis flight route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    SkyTeam is the only airline alliance operating flights between Panama City and St. Louis.

  • On which days can I fly direct from Panama City to St. Louis?

    There are nonstop flights from Panama City to St. Louis on a daily basis.

  • Which is the best airline for flights from Panama City to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Panama City to St. Louis are Southwest and Delta. With an average price for the route of $364 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $362 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $208 or less one-way and $364 or less round-trip.

Prefer to fly direct from Panama City to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City NW Florida Beaches to Lambert-St Louis.
Find which airlines fly direct from Panama City NW Florida Beaches Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Panama City NW Florida Beaches to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Panama City NW Florida Beaches

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top airlines flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4335 reviews
8.1Boarding
8.6Crew
7.0Food
7.5Entertainment
8.0Comfort
Airline reviews

Communication about the delayed flight was poor. We were told to move gates three times but that was bad information. We went from gate 128 to gate 126 and then to gate 123 and back to gate 126. Communication about the delay was bad. Ended up being 1 1/2 hour late getting home.

2.0 MediocreDavid, Apr 2026
MCO - MCI
Read more Southwest reviews

Communication about the delayed flight was poor. We were told to move gates three times but that was bad information. We went from gate 128 to gate 126 and then to gate 123 and back to gate 126. Communication about the delay was bad. Ended up being 1 1/2 hour late getting home.

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

Southwest continues to do less for more money. Flight attendants used to be fun and friendly. But now it’s like they don’t even see you. Such a shame.

I liked it better when you were truer to your roots Am paying more for less fun

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

Long layover between flights to Long Island from BWI - need better coordination between flights

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

An entire day of delays. Cost lots of money. Meals and a hotel.

Great plane, great attendants,great flight crew,on time. Wonderful flight home..

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports