$111 Find Cheap Flights from Panama City to North America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to North America departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama City to North America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
New York
New Yorknonstop$239
Los Angeles
Los Angeles1 stop$375
Las Vegas
Las Vegas1 stop$387
Chicago
Chicagononstop$271
San Francisco
San Francisco1 stop$375
Miami
Miami1 stop$355
Boston
Boston1 stop$417
Washington, D.C.
Baltimore1 stop$287
Denver
Denver1 stop$386
Fort Lauderdale
Fort Lauderdale1 stop$355
Seattle
Seattle1 stop$375
Atlanta
Atlantanonstop$219
Tampa
Tampa1 stop$375
Houston
Houstonnonstop$205
Cancún
Cancún1 stop$521
Honolulu
Honolulu2 stops$505
San Diego
San Diego1 stop$387
New York
New Yorknonstop$239
Los Angeles
Los Angeles1 stop$375
Las Vegas
Las Vegas1 stop$387
Chicago
Chicagononstop$271
San Francisco
San Francisco1 stop$375
Miami
Miami1 stop$355
Boston
Boston1 stop$417
Washington, D.C.
Baltimore1 stop$287
Denver
Denver1 stop$386
Fort Lauderdale
Fort Lauderdale1 stop$355
Seattle
Seattle1 stop$375
Atlanta
Atlantanonstop$219
Tampa
Tampa1 stop$375
Houston
Houstonnonstop$205
Cancún
Cancún1 stop$521
Honolulu
Honolulu2 stops$505
San Diego
San Diego1 stop$387

Book Cheap Panama City to North America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to North America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to North America

Tue, Apr 7 - Tue, Apr 14
Southwest Logo
7:55 am - 12:20 pm
ECP
-
HOU
4h 25m
1 stop
Southwest Logo
2:40 pm - 4:20 pm
HOU
-
ECP
1h 40mnonstop
$215Southwest
Tue, Apr 7 - Tue, Apr 14
Southwest Logo
7:55 am - 12:20 pm
ECP
-
HOU
4h 25m
1 stop
Southwest Logo
10:55 am - 2:25 pm
HOU
-
ECP
3h 30m
1 stop
$220Southwest
Thu, Apr 9 - Sat, Apr 11
Southwest Logo
12:20 pm - 2:20 pm
ECP
-
HOU
2h 00mnonstop
Southwest Logo
3:10 pm - 4:50 pm
HOU
-
ECP
1h 40mnonstop
$221Southwest
Tue, Apr 7 - Tue, Apr 14
Southwest Logo
10:10 am - 12:05 pm
ECP
-
HOU
1h 55mnonstop
Southwest Logo
2:40 pm - 4:20 pm
HOU
-
ECP
1h 40mnonstop
$223Southwest
Thu, Apr 23 - Mon, Apr 27
Delta Logo
12:59 pm - 4:30 pm
ECP
-
LGA
2h 31mnonstop
Delta Logo
10:15 am - 12:19 pm
LGA
-
ECP
3h 04mnonstop
$239Delta
Fri, Apr 17 - Tue, Apr 21
Delta Logo
4:31 pm - 11:41 pm
ECP
-
LGA
6h 10m
1 stop
Delta Logo
10:15 am - 12:19 pm
LGA
-
ECP
3h 04mnonstop
$249Delta
Thu, Apr 23 - Mon, Apr 27
American Airlines Logo
4:40 pm - 10:16 pm
ECP
-
JFK
4h 36m
1 stop
American Airlines Logo
7:29 pm - 11:46 pm
JFK
-
ECP
5h 17m
1 stop
$258American Airlines
Tue, Apr 21 - Wed, May 13
United Airlines Logo
10:29 am - 1:15 pm
ECP
-
ORD
2h 46mnonstop
United Airlines Logo
10:47 am - 1:18 pm
ORD
-
ECP
2h 31mnonstop
$271United Airlines
Thu, Apr 23 - Mon, Apr 27
American Airlines Logo
4:40 pm - 11:25 pm
ECP
-
LGA
5h 45m
1 stop
American Airlines Logo
6:00 am - 10:03 am
LGA
-
ECP
5h 03m
1 stop
$277American Airlines
Fri, Aug 14 - Fri, Aug 21
United Airlines Logo
1:39 pm - 11:22 pm
ECP
-
LGA
8h 43m
1 stop
United Airlines Logo
6:05 am - 12:58 pm
LGA
-
ECP
7h 53m
2 stops
$285United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to North America flights

Get data-powered insights and trends into flights from Panama City to North America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Panama City to North America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to North America from Panama City found in the last 72 hours was to Atlanta, at $246 round-trip. The most popular route is from Panama City (ECP) to Atlanta (ATL), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $246.

Can I save money by flying with a layover from Panama City to North America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $385, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to North America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to North America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to North America is May, when tickets cost $293 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $417 and $408 respectively.

Good to know

Low seasonJanuary
Cheapest flight$111
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Panama City to Houston Hobby Airport

FAQs - booking North America flights

  • How does KAYAK find such low prices on flights from Panama City to North America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to North America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to North America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to North America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to North America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to North America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to North America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to North America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to North America

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: Atlanta $206 one-way - $358 round-trip; Charlotte $209 one-way - $367 round-trip; Houston $258 one-way - $376 round-trip

Reviews of the top 5 airlines serving from Panama City to North America

 
Need help choosing which airline to fly with from Panama City to North America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4323 reviews
7.5Entertainment
8.1Boarding
8.6Crew
7.0Food
8.0Comfort
Airline reviews

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

10.0 ExcellentEric, Mar 2026
MCO - BNA
Read more Southwest reviews

I was supposed to be on a later flight. When I showed up at the gate, the woman working there was extremely helpful getting moved up to this earlier flight.

Long layover between flights to Long Island from BWI - need better coordination between flights

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

An entire day of delays. Cost lots of money. Meals and a hotel.

I appreciate the staff who allowed me to board though I arrived a little late! Regarding the assigned seating, I had booked my flight before this change and wasn't aware of the change at the time, and so I didn't select a seat at booking as I didn't realize it was relevant. Better communication about the change would have been helpful for preparing.

Departure was delayed more than 1/2 hour while we waited for luggage (only) transfer from another flight/plane. Once approved for takeoff, the flight was excellent.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Business class seats felt very cramped compared to other airlines.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Plane outlets in my row not working to charge phone. Staff response was, well it should be. Plug into seed for volume not working well. Had to find the sweet spot for plug in or it would shut off and on.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Very turbulent trip made it pretty bearable, plus the lack of refreshments served and the lack of any air conditioning before takeoff which took an hour or more.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

All went very well. We used the AIFI Airport, such a lovely facility. Definitely needs better transportation options to get there.

Both ground crew and flight crew were rude, and did not provide any level of service. They made it very difficult as we were traveling with a passenger the required assistance.

From the check-in, to the flight, and arriving, everything went very smoothly. Unfortunately, when I received my baggage it was severely damaged. I have a hard shelled suitcase and it was completely smashed it. I’m not sure how this could happened but I am extremely disappointed that my belongings were damaged beyond repair and continued use.

Really nice, all good, nice crew and all on time

Unfortunately I had an awful boarding experience. Our first flight with Aeromexico was fine and landed on time however it couldn’t find a gate and we were late which made us lose our connecting flight with Aeromexico. The staff handled it horribly when we explained our situation and would not led us board when we missed the boarding time by a couple minutes. The staff were extremely rude and did not attempt to even help us. Because of this incident, my husband and I missed a full day of work which negatively impacted our salary which we need. Please compensate us for the work that we missed.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Good, the flight from Miami to Mexico City was better than Mexico City to Miami

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Flights were constantly delayed. CRW took 50 minutes to get bags

Appreciate having multiple food options for allergies. Nice to have an extra seat between us for comfort.

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

I didn't end up taking this flight. I got up at 4am for a flight that was supposed to board at 6am - at 5:55am you delayed the flight to 10am. The airport is under construction so I switched to a later flight as I wasn't going to sit in the airport for 4 hours. They said the delay was due to the crew needing rest from a flight coming in late the night before - if that was the case then I think you should have delayed the flight much sooner so that passengers wouldn't get up so early and get to the airport to sit and wait.

The flight attendants and the service is getting worse by the day.

Other than nearly three hour delay for maintenance issues, everything went smooth

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

Everything you need to know for your flight to North America

Information on your arrival and departure airports