$164 Find Cheap Flights from Panama City to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to South Carolina departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$253
Myrtle Beach
Myrtle Beach1 stop$283
Charlotte
Charlottenonstop$229
Charleston
Charleston1 stop$253
Myrtle Beach
Myrtle Beach1 stop$283
Charlotte
Charlottenonstop$229

Book Cheap Panama City to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to South Carolina

Sat, Feb 21 - Wed, Feb 25
Delta Logo
12:15 pm - 5:21 pmECP-GSP
4h 06m1 stop
Delta Logo
8:19 am - 1:25 pmGSP-ECP
6h 06m1 stop
$249Delta
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Sat, Feb 14 - Wed, Feb 18
Delta Logo
12:15 pm - 5:53 pmECP-CHS
4h 38m1 stop
Delta Logo
8:30 am - 1:25 pmCHS-ECP
5h 55m1 stop
$253Delta
Find Deal
Sat, Feb 21 - Wed, Feb 25
Delta Logo
12:15 pm - 5:21 pmECP-GSP
4h 06m1 stop
Delta Logo
6:49 am - 8:41 amGSP-ECP
2h 52m1 stop
$268Delta
Find Deal
Sat, Feb 14 - Wed, Feb 18
Delta Logo
2:14 pm - 7:56 pmECP-CHS
4h 42m1 stop
Delta Logo
8:30 am - 1:25 pmCHS-ECP
5h 55m1 stop
$277Delta
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Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
2:53 pm - 6:56 pmECP-MYR
3h 03m1 stop
American Airlines Logo
5:28 am - 9:24 amMYR-ECP
4h 56m1 stop
$377American Airlines
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Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
4:30 pm - 11:59 pmECP-CHS
6h 29m1 stop
American Airlines Logo
6:00 am - 1:14 pmCHS-ECP
8h 14m2 stops
$388American Airlines
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Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
4:30 pm - 10:23 pmECP-CHS
4h 53m1 stop
American Airlines Logo
6:00 am - 1:14 pmCHS-ECP
8h 14m2 stops
$406American Airlines
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Thu, Apr 23 - Sun, Apr 26
Southwest Logo
7:10 am - 3:10 pmECP-MYR
7h 00m2 stops
Southwest Logo
10:20 am - 5:30 pmMYR-ECP
8h 10m1 stop
$420Southwest
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Thu, Apr 23 - Sun, Apr 26
Southwest Logo
7:10 am - 3:10 pmECP-MYR
7h 00m2 stops
Southwest Logo
10:20 am - 9:40 pmMYR-ECP
12h 20m2 stops
$425Southwest
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Tue, Dec 23 - Tue, Dec 30
Southwest Logo
12:50 pm - 7:40 pmECP-MYR
5h 50m1 stop
Southwest Logo
7:00 am - 9:20 pmMYR-ECP
15h 20m2 stops
$455Southwest
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to South Carolina flights

Get data-powered insights and trends into flights from Panama City to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to South Carolina departing in February.

What is the cheapest month to fly from Panama City to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to South Carolina is August, when tickets cost $266 (return) on average. On the other hand, the most expensive months are April and June, when the average cost of round-trip tickets is $587 and $457 respectively.

Good to know

Low seasonAugust
Cheapest flight$164
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Panama City to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: Charlotte $261 one-way - $349 round-trip

Reviews of the top airline flying from Panama City to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Panama City to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7999 reviews
7.9Comfort
7.3Food
8.5Crew
7.9Entertainment
8.1Boarding
Airline reviews

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

10.0 ExcellentPatricia Lynn, Nov 2025EYW - ATL
Read more Delta reviews

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

Everything you need to know for your flight from Panama City to South Carolina

Information on your arrival and departure airports