$115 Find Cheap Flights from Panama City to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to South Carolina departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama City to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$233
Myrtle Beach
Myrtle Beach1 stop$331
Charlotte
Charlotte1 stop$257
Charleston
Charleston1 stop$233
Myrtle Beach
Myrtle Beach1 stop$331
Charlotte
Charlotte1 stop$257

Book Cheap Panama City to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to South Carolina

Tue, Aug 11 - Sat, Aug 15
Delta Logo
6:00 am - 11:02 am
ECP
-
GSP
4h 02m
1 stop
Delta Logo
7:28 am - 10:42 am
GSP
-
ECP
4h 14m
1 stop
$227Delta
Tue, Aug 11 - Sat, Aug 15
Southwest Logo
7:45 am - 12:25 pm
ECP
-
GSP
3h 40m
1 stop
Southwest Logo
6:45 am - 2:55 pm
GSP
-
ECP
9h 10m
2 stops
$233Southwest
Mon, Aug 17 - Thu, Aug 27
Delta Logo
7:35 am - 11:54 am
ECP
-
CHS
3h 19m
1 stop
Delta Logo
7:59 pm - 11:30 pm
CHS
-
ECP
4h 31m
1 stop
$233Delta
Tue, Aug 11 - Sat, Aug 15
Southwest Logo
11:30 am - 7:25 pm
ECP
-
GSP
6h 55m
2 stops
Southwest Logo
6:45 am - 2:55 pm
GSP
-
ECP
9h 10m
2 stops
$239Southwest
Wed, Sep 9 - Sat, Sep 12
Southwest Logo
7:45 am - 7:15 pm
ECP
-
CHS
10h 30m
2 stops
Southwest Logo
8:05 am - 1:55 pm
CHS
-
ECP
6h 50m
1 stop
$243Southwest
Thu, Aug 20 - Mon, Aug 24
Southwest Logo
10:00 am - 9:25 pm
ECP
-
CHS
10h 25m
1 stop
Southwest Logo
6:35 am - 3:45 pm
CHS
-
ECP
10h 10m
2 stops
$244Southwest
Wed, Sep 9 - Sat, Sep 12
Southwest Logo
7:45 am - 7:15 pm
ECP
-
CHS
10h 30m
2 stops
Southwest Logo
8:05 am - 6:05 pm
CHS
-
ECP
11h 00m
2 stops
$254Southwest
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:25 pm - 10:46 pm
ECP
-
GSP
7h 21m
1 stop
United Airlines Logo
6:30 am - 1:44 pm
GSP
-
ECP
8h 14m
1 stop
$309United Airlines
Tue, Oct 6 - Sat, Oct 10
American Airlines Logo
5:42 pm - 10:52 pm
ECP
-
MYR
4h 10m
1 stop
American Airlines Logo
8:14 pm - 11:53 pm
MYR
-
ECP
4h 39m
1 stop
$367American Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:25 pm - 11:20 am
ECP
-
MYR
19h 55m
2 stops
United Airlines Logo
11:30 am - 1:44 pm
MYR
-
ECP
27h 14m
2 stops
$646United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to South Carolina flights

Get data-powered insights and trends into flights from Panama City to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to South Carolina is June, when tickets cost $0 (return) on average. On the other hand, the most expensive months are May and December, when the average cost of round-trip tickets is $636 and $533 respectively.

Find deals

Good to know

Low seasonSeptember
Cheapest flight$115
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly and prices are also 25% lower on average.
Flight from Panama City to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Panama City to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Panama City to the following destinations at these prices or less: Charlotte $280 one-way - $396 round-trip

Reviews of the top airline flying from Panama City to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Panama City to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8463 reviews
7.8Comfort
8.5Crew
8.1Boarding
7.2Food
7.8Entertainment
Airline reviews

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

8.0 ExcellentRoseanne, Jul 2026
FLL - ATL
Read more Delta reviews

I had only one problem. The temperature on the flight was too COLD. I froze throughout the flight. I thought it might be only my problem but when I went to the restroom during the flight, I saw several people huddling in their jackets. A couple had their winter coats on and I was jealous since I had only a very light jacket.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

Planes were clean, no water or snacks on either flight.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Everything you need to know for your flight from Panama City to South Carolina

Information on your arrival and departure airports

Panama City (ECP)