PTY - SDQ

$246 Find Cheap Flights from Panama City to Santo Domingo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santo Domingo, as well as popular online travel agencies
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Cheap Flights from Panama City to Santo Domingo

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Panama City to Santo Domingo

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama City to Santo Domingo.
Discover the best prices for you by selecting your travel dates on KAYAK.
Avianca Logo
3:20 am - 10:50 amPTY-SDQ
6h 30m1 stop
Avianca Logo
11:45 am - 9:10 pmSDQ-PTY
10h 25m1 stop
$246Avianca
Find Deal
Wed, May 28 - Mon, Jun 2
Avianca Logo
3:20 am - 5:15 pmPTY-SDQ
12h 55m1 stop
Avianca Logo
6:10 pm - 8:55 amSDQ-PTY
15h 45m1 stop
$286Avianca
Find Deal
Sat, Oct 18 - Fri, Oct 24
 Logo
11:05 am - 5:15 pmPTY-SDQ
5h 10m1 stop
 Logo
6:54 am - 12:10 amSDQ-PTY
18h 16m2 stops
Wed, Jun 4 - Sat, Jun 14
 Logo
3:20 am - 1:59 pmPTY-SDQ
33h 39m2 stops
 Logo
11:45 am - 9:10 pmSDQ-PTY
10h 25m1 stop
Tue, Jun 3 - Sat, Jun 14
Copa Airlines Logo
9:37 am - 1:10 pmPTY-SDQ
2h 33mnonstop
Copa Airlines Logo
11:52 am - 1:29 pmSDQ-PTY
2h 37mnonstop
$429Copa Airlines
Find Deal
Thu, May 29 - Fri, Jun 27
Copa Airlines Logo
12:44 pm - 4:17 pmPTY-SDQ
2h 33mnonstop
Copa Airlines Logo
8:53 am - 10:30 amSDQ-PTY
2h 37mnonstop
$481Copa Airlines
Find Deal
Tue, May 13 - Mon, May 19
United Airlines Logo
7:55 am - 1:50 amPTY-SDQ
16h 55m2 stops
United Airlines Logo
3:20 pm - 4:12 pmSDQ-PTY
25h 52m2 stops
$857United Airlines
Find Deal
Mon, May 19 - Thu, Jun 19
United Airlines Logo
10:00 am - 1:50 amPTY-SDQ
14h 50m2 stops
United Airlines Logo
1:10 pm - 2:14 pmSDQ-PTY
26h 04m2 stops
$1,139United Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
Delta Logo
2:13 pm - 12:19 amPTY-SDQ
33h 06m2 stops
Delta Logo
2:41 pm - 7:53 pmSDQ-PTY
30h 12m1 stop
$5,776Delta
Find Deal
Mon, May 12 - Fri, May 16
Delta Logo
2:13 pm - 1:16 pmPTY-SDQ
22h 03m1 stop
Delta Logo
7:05 am - 7:53 pmSDQ-PTY
13h 48m2 stops
$5,822Delta
Find Deal
Wed, May 14 - Sat, May 17
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KAYAK's insights & trends for Panama City to Santo Domingo flights

Get data-powered insights and trends into flights from Panama City to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Santo Domingo?

The average price of all round-trip flights from Panama City to Santo Domingo clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Santo Domingo, you should consider leaving on a Thursday and avoid Sundays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Wednesdays and the most expensive ones on Mondays.

What is the cheapest month to fly from Panama City to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Santo Domingo is June, where tickets cost $350 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $425 and $417 respectively.

How far in advance should I book a flight from Panama City to Santo Domingo?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Santo Domingo, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonMarch
High seasonDecember
Cheapest flight$246
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Panama City to Santo Domingo

When to book flights from Panama City to Santo Domingo

Are your dates flexible? Find out the best times to travel from Panama City to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Santo Domingo

  • What is the cheapest flight from Panama City to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Panama City to Santo Domingo was $270 for a one-way ticket and $246 for a round-trip.

  • Do I need a passport to fly between Panama City and Santo Domingo?

    Yes

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Santo Domingo?

    Only Delta offers inflight Wi-Fi service on the Panama City to Santo Domingo flight route.

  • Which aircraft models fly most regularly from Panama City to Santo Domingo?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Santo Domingo flight route.

  • Which airline alliances offer flights from Panama City to Santo Domingo?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Panama City to Santo Domingo?

    There are nonstop flights from Panama City to Santo Domingo on a daily basis.

  • Which is the best airline for flights from Panama City to Santo Domingo, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Santo Domingo are Copa Airlines and Avianca. With an average price for the route of $417 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $349 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Panama City to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Panama City with another airline. Booking your flights between Panama City and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Santo Domingo

  • Looking for a cheap flight? 25% of our users found flights on this route for $473 or less one-way and $428 or less round-trip.

Prefer to fly direct from Panama City to Santo Domingo?

Find which airlines fly direct from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Santo Domingo Las Americas

Monday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Tuesday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Wednesday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Thursday

Copa Airlines, KLM, Air France, +1 more

Copa Airlines, KLM, +2 more

Friday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Saturday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Sunday

Copa Airlines, KLM, Air France, +1 more

Copa Airlines, KLM, +2 more

See more direct flights

Direct returns

Santo Domingo Las Americas to Panama City Tocumen Intl

Monday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Tuesday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Wednesday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Thursday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Friday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Saturday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

Sunday

Air France, Copa Airlines, KLM, +1 more

Air France, Copa Airlines, +2 more

See more direct flights
See more direct flights

Top airlines flying from Panama City to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1414 reviews
6.8Entertainment
8.1Crew
7.8Boarding
6.8Food
7.4Comfort
Airline reviews

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

2.0 MediocreCec, Apr 2025PTY - IAD
Read more Copa Airlines reviews

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

It was good, plane is a bit older so seats are somewhat flat

Copa stranded us ans then tried to charge us thousands to leave Panama.

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

I loved my experience. Very safe, Very informative and very friendly.

Check in person said there would be lunch. We were first class passengers and lunch was chips.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

So so, you feel like you have to pay for everything each time

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

Everything you need to know for your flight from Panama City to Santo Domingo

Information on your arrival and departure airports

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