PTY - SDQ

$241 Find Cheap Flights from Panama City to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santo Domingo, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Santo Domingo (PTY-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santo Domingo

Thu, Oct 16 - Tue, Oct 21
Copa Airlines Logo
6:55 pm - 10:25 pmPTY-SDQ
2h 30mnonstop
Copa Airlines Logo
8:58 am - 10:30 amSDQ-PTY
2h 32mnonstop
$450Copa Airlines
Find Deal
Thu, Oct 30 - Wed, Nov 5
Avianca Logo
2:55 am - 4:50 pmPTY-SDQ
12h 55m1 stop
Avianca Logo
5:45 pm - 8:50 amSDQ-PTY
16h 05m1 stop
$451Avianca
Find Deal
Fri, Oct 31 - Mon, Nov 10
Avianca Logo
2:55 am - 4:50 pmPTY-SDQ
12h 55m1 stop
Avianca Logo
5:45 pm - 12:40 amSDQ-PTY
7h 55m1 stop
$452Avianca
Find Deal
Sat, Nov 1 - Mon, Nov 10
Copa Airlines Logo
10:55 pm - 2:26 amPTY-SDQ
2h 31mnonstop
Copa Airlines Logo
11:55 am - 1:32 pmSDQ-PTY
2h 37mnonstop
$453Copa Airlines
Find Deal
Fri, Oct 17 - Fri, Oct 24
Copa Airlines Logo
12:44 pm - 4:15 pmPTY-SDQ
2h 31mnonstop
Copa Airlines Logo
6:24 pm - 7:55 pmSDQ-PTY
2h 31mnonstop
$461Copa Airlines
Find Deal
Thu, Oct 30 - Wed, Nov 5
Copa Airlines Logo
6:55 pm - 10:25 pmPTY-SDQ
2h 30mnonstop
Copa Airlines Logo
8:55 am - 10:30 amSDQ-PTY
2h 35mnonstop
$467Copa Airlines
Find Deal
Sat, Nov 1 - Wed, Nov 5
Copa Airlines Logo
10:55 pm - 2:26 amPTY-SDQ
2h 31mnonstop
Copa Airlines Logo
8:55 am - 10:30 amSDQ-PTY
2h 35mnonstop
$469Copa Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 11
Copa Airlines Logo
7:28 am - 10:58 amPTY-SDQ
2h 30mnonstop
Copa Airlines Logo
6:39 pm - 8:14 pmSDQ-PTY
2h 35mnonstop
$478Copa Airlines
Find Deal
Sat, Dec 20 - Mon, Jan 19
Copa Airlines Logo
10:55 pm - 2:26 amPTY-SDQ
2h 31mnonstop
Copa Airlines Logo
2:11 pm - 3:47 pmSDQ-PTY
2h 36mnonstop
$479Copa Airlines
Find Deal
Fri, Feb 13 - Sun, Feb 22
Multiple Airlines Logo
2:55 am - 4:50 pmPTY-SDQ
12h 55m1 stop
Multiple Airlines Logo
3:35 pm - 2:55 pmSDQ-PTY
24h 20m2 stops
$525Multiple Airlines
Find Deal

Everything you should know

Top airlines
Copa Airlines
Cheapest • from $450 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 32% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
January
Cheapest • 2% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$450
Typical prices: $394-500
Copa Airlines
Thu 10/16Tue 10/21
PTY - SDQ • Non-stop
Cheapest non-stop
$450
Typical prices: $394-503
Copa Airlines
Fri 10/17Mon 10/20
PTY - SDQ • Non-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Booking Insights

KAYAK's insights & trends for Panama City to Santo Domingo flights

Get data-powered insights and trends into flights from Panama City to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Santo Domingo?

What’s the cheapest day of the week to fly from Panama City to Santo Domingo?

The average price of all round-trip flights from Panama City to Santo Domingo clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Santo Domingo, you should consider leaving on a Thursday and avoid Mondays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Thursdays and the most expensive ones on Mondays.

What is the cheapest month to fly from Panama City to Santo Domingo?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Santo Domingo is January, where tickets cost $417 (return) on average. On the other hand, the most expensive months are December and September, where the average cost of round-trip tickets is $452 and $449 respectively.

Can I save money by flying with a layover from Panama City to Santo Domingo?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $452, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Santo Domingo?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Santo Domingo, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Santo Domingo, you should book around 3 weeks before departure, which saves you about 32% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$241
Best time to beat the crowds with an average 0% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to Santo Domingo

When to book flights from Panama City to Santo Domingo

Are your dates flexible? Find out the best times to travel from Panama City to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Santo Domingo

  • What is the cheapest flight from Panama City to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Panama City to Santo Domingo was $241 for a one-way ticket and $450 for a round-trip.

  • Do I need a passport to fly between Panama City and Santo Domingo?

    Yes

  • Which aircraft models fly most regularly from Panama City to Santo Domingo?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Santo Domingo flight route.

  • Which airline alliances offer flights from Panama City to Santo Domingo?

    Star Alliance is the only airline alliance operating flights between Panama City and Santo Domingo.

  • On which days can I fly direct from Panama City to Santo Domingo?

    There are nonstop flights from Panama City to Santo Domingo on a daily basis.

  • Which is the best airline for flights from Panama City to Santo Domingo, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Santo Domingo are Copa Airlines and Avianca. With an average price for the route of $448 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $345 and an overall rating of 6.7.

  • How does KAYAK find such low prices on flights from Panama City to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Panama City with another airline. Booking your flights between Panama City and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Santo Domingo

  • Looking for a cheap flight? 25% of our users found flights on this route for $449 or less round-trip.

Prefer to fly direct from Panama City to Santo Domingo?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Santo Domingo Las Americas.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Santo Domingo Las Americas

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Santo Domingo Las Americas to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1537 reviews
7.4Comfort
6.8Entertainment
7.8Boarding
8.1Crew
6.8Food
Airline reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

10.0 ExcellentNeil, Aug 2025PTY - BGI
Read more Copa Airlines reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Did upgrade, travel in business it was great (more room I could sleep)

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Not what it used to be. The sale of food makes them look greedy!

Avianca is not what it used to be. So disappointing

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

The chicken that was served in business class was cold!

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Everything you need to know for your flight from Panama City to Santo Domingo

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