SDQ - PTY

$455 Find Cheap Flights from Santo Domingo to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Panama City departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$455
Overall average: $524
Avianca
vr 1/23za 1/31
SDQ - PTY • 1 stop
Cheapest non-stop
$525
Typical prices: $486-$621
Copa Airlines
di 1/20za 1/24
SDQ - PTY • Non-stop
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 31% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 14% price drop
April
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Panama City (SDQ-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Panama City

vr, jan. 23 - za, jan. 31
Avianca Logo
5:45 pm - 12:40 am
SDQ
-
PTY
7h 55m1 stop
Avianca Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$455Avianca
vr, jan. 16 - ma, jan. 19
Avianca Logo
5:45 pm - 12:40 am
SDQ
-
PTY
7h 55m1 stop
Avianca Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$466Avianca
do, jan. 15 - vr, jan. 16
Avianca Logo
12:20 pm - 4:55 pm
SDQ
-
PTY
5h 35m1 stop
Avianca Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$477Avianca
di, jan. 20 - za, jan. 24
Avianca Logo
12:20 pm - 1:00 am
SDQ
-
PTY
13h 40m1 stop
Avianca Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$501Avianca
di, jan. 27 - di, feb. 3
Multiple Airlines Logo
5:53 pm - 8:50 am
SDQ
-
PTY
15h 57m2 stops
Multiple Airlines Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$506Multiple Airlines
wo, feb. 18 - wo, feb. 25
Multiple Airlines Logo
9:28 am - 2:00 pm
SDQ
-
PTY
29h 32m2 stops
Multiple Airlines Logo
5:50 pm - 11:25 am
PTY
-
SDQ
16h 35m1 stop
$515Multiple Airlines
do, feb. 5 - zo, feb. 8
Avianca Logo
12:20 pm - 1:00 am
SDQ
-
PTY
13h 40m1 stop
Avianca Logo
9:45 am - 4:50 pm
PTY
-
SDQ
6h 05m1 stop
$516Avianca
do, feb. 19 - di, feb. 24
Multiple Airlines Logo
12:20 pm - 4:55 pm
SDQ
-
PTY
5h 35m1 stop
Multiple Airlines Logo
2:55 am - 4:20 pm
PTY
-
SDQ
12h 25m2 stops
$518Multiple Airlines
vr, apr. 17 - di, apr. 21
Multiple Airlines Logo
6:10 pm - 12:45 am
SDQ
-
PTY
7h 35m1 stop
Multiple Airlines Logo
3:20 am - 4:27 pm
PTY
-
SDQ
12h 07m2 stops
$524Multiple Airlines
di, jan. 20 - za, jan. 24
Copa Airlines Logo
12:40 pm - 2:15 pm
SDQ
-
PTY
2h 35mnonstop
Copa Airlines Logo
10:55 pm - 2:17 am
PTY
-
SDQ
2h 22mnonstop
$525Copa Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to Panama City flights

Get data-powered insights and trends into flights from Santo Domingo to Panama City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to Panama City?

The average price of all round-trip flights from Santo Domingo to Panama City clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santo Domingo to Panama City, look for departures on Thursdays and avoid leaving on a Monday, as it's usually the priciest day. When flying back from Panama City, Thursday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Santo Domingo to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Panama City is May, where tickets cost $429 (return) on average. On the other hand, the most expensive months are January and November, where the average cost of round-trip tickets is $524 and $524 respectively.

Can I save money by flying with a layover from Santo Domingo to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $524, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santo Domingo to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Panama City, you should book around 3 weeks before departure, which saves you about 31% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$362
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Santo Domingo to Panama City

When to book flights from Santo Domingo to Panama City

Are your dates flexible? Find out the best times to travel from Santo Domingo to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Panama City

  • What is the cheapest flight from Santo Domingo to Panama City?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Panama City was $362 for a one-way ticket and $455 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Panama City?

    Yes

  • Which airports will I be using when flying from Santo Domingo to Panama City?

    When flying out of Santo Domingo you will be using Santo Domingo Las Americas. You will be landing at Panama City, also known as Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Santo Domingo to Panama City?

    JetBlue, Delta, and American Airlines offer inflight Wi-Fi service on the Santo Domingo to Panama City flight route.

  • Which aircraft models fly most regularly from Santo Domingo to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Santo Domingo to Panama City flight route.

  • Which airline alliances offer flights from Santo Domingo to Panama City?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Panama City.

  • On which days can I fly direct from Santo Domingo to Panama City?

    There are nonstop flights from Santo Domingo to Panama City on a daily basis.

  • Which is the best airline for flights from Santo Domingo to Panama City, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Panama City are Copa Airlines and Avianca. With an average price for the route of $524 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $346 and an overall rating of 6.6.

  • How does KAYAK find such low prices on flights from Santo Domingo to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santo Domingo to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $230 or less one-way and $310 or less round-trip.

Prefer to fly direct from Santo Domingo to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santo Domingo Las Americas to Panama City Tocumen Intl.
Find which airlines fly direct from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santo Domingo Las Americas to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santo Domingo Las Americas

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Santo Domingo to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1566 reviews
6.8Food
6.8Entertainment
7.4Comfort
8.1Crew
7.8Boarding
Airline reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

2.0 MediocreAnonymous, Dec 2025
LAS - PTY
Read more Copa Airlines reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

We waited for one hour to deboard the plane after landing. That could be better

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Everything you need to know for your flight from Santo Domingo to Panama City

Information on your arrival and departure airports