SDQ - PTY

$257 Find Cheap Flights from Santo Domingo to Panama City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Panama City departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$547
Typical prices: $423-$627
Avianca
Thu 8/20Tue 8/25
SDQ - PTY • 1 stop
Cheapest non-stop
$630
Typical prices: $523-$666
Copa Airlines
Tue 10/27Sun 11/1
SDQ - PTY • Non-stop
Top airlines
Cheapest • from $547 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Copa Airlines. Average duration is 2h 32m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 96% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 26% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 5% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Panama City (SDQ-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Panama City

Thu, Aug 20 - Tue, Aug 25
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 5:55 pm
PTY
-
SDQ
12h 30m
1 stop
$547Avianca
Tue, Aug 4 - Tue, Aug 11
Avianca Logo
6:50 pm - 12:35 am
SDQ
-
PTY
6h 45m
1 stop
Avianca Logo
10:10 am - 5:55 pm
PTY
-
SDQ
6h 45m
1 stop
$549Avianca
Fri, Aug 14 - Sun, Aug 16
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 11:50 am
PTY
-
SDQ
6h 25m
1 stop
$551Avianca
Tue, Aug 4 - Sun, Aug 9
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 5:55 pm
PTY
-
SDQ
12h 30m
1 stop
$552Avianca
Fri, Nov 6 - Mon, Nov 9
Avianca Logo
5:45 pm - 8:50 am
SDQ
-
PTY
16h 05m
1 stop
Avianca Logo
5:50 pm - 11:25 am
PTY
-
SDQ
16h 35m
1 stop
$554Avianca
Thu, Aug 27 - Sun, Aug 30
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
10:10 am - 5:55 pm
PTY
-
SDQ
6h 45m
1 stop
$557Avianca
Sat, Aug 15 - Fri, Aug 21
Multiple Airlines Logo
12:45 pm - 2:15 pm
SDQ
-
PTY
26h 30m
1 stop
Multiple Airlines Logo
5:55 pm - 7:18 pm
PTY
-
SDQ
24h 23m
2 stops
$558Multiple Airlines
Thu, Aug 6 - Fri, Aug 14
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
10:10 am - 5:55 pm
PTY
-
SDQ
6h 45m
1 stop
$560Avianca
Wed, Sep 23 - Sun, Sep 27
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
5:55 pm - 11:50 am
PTY
-
SDQ
16h 55m
1 stop
$561Avianca
Wed, Aug 5 - Sun, Aug 9
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 5:55 pm
PTY
-
SDQ
12h 30m
1 stop
$563Avianca
Booking Insights

KAYAK's insights & trends for Santo Domingo to Panama City flights

Get data-powered insights and trends into flights from Santo Domingo to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Panama City departing in August.

Flight prices are typical for this route right now.

Flights to Panama City from Santo Domingo usually cost between $457 and $635 in August.
The lowest price found in the past 5 days was $547 on Avianca (Aug 20-Aug 25).

What’s the cheapest day of the week to fly from Santo Domingo to Panama City?

The average price of all round-trip flights from Santo Domingo to Panama City clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santo Domingo to Panama City, look for departures on Thursdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama City, Saturday is the cheapest day to fly and Thursday is the most expensive.

What is the cheapest month to fly from Santo Domingo to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Panama City is August, where tickets cost $520 (return) on average. On the other hand, the most expensive months are May and March, where the average cost of round-trip tickets is $608 and $590 respectively.

Can I save money by flying with a layover from Santo Domingo to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $608 on average.

How far in advance should I book a flight from Santo Domingo to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Panama City, you should book around 3 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low season

May

Cheapest flight

$257
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly with an average 7% increase in price.
Flight from Santo Domingo to Panama City

When to book flights from Santo Domingo to Panama City

Are your dates flexible? Find out the best times to travel from Santo Domingo to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Panama City

  • What is the cheapest flight from Santo Domingo to Panama City?

    In the last 5 days, the lowest price for a flight from Santo Domingo to Panama City was $257 for a one-way ticket and $547 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Panama City?

    Yes

  • Which airports will I be using when flying from Santo Domingo to Panama City?

    When flying out of Santo Domingo you will be using Santo Domingo Las Americas. You will be landing at Panama City, also known as Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Santo Domingo to Panama City?

    American Airlines, and JetBlue offer inflight Wi-Fi service on the Santo Domingo to Panama City flight route.

  • Which aircraft models fly most regularly from Santo Domingo to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Santo Domingo to Panama City flight route.

  • Which airline alliances offer flights from Santo Domingo to Panama City?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Panama City.

  • On which days can I fly direct from Santo Domingo to Panama City?

    There are nonstop flights from Santo Domingo to Panama City on a daily basis.

  • Which is the best airline for flights from Santo Domingo to Panama City, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Panama City are Copa Airlines and Avianca. With an average price for the route of $600 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $482 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Santo Domingo to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santo Domingo to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $221 or less one-way and $397 or less round-trip.

Prefer to fly direct from Santo Domingo to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santo Domingo Las Americas to Panama City Tocumen Intl.
Find which airlines fly direct from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santo Domingo Las Americas to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santo Domingo Las Americas

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Santo Domingo to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1562 reviews
8.1Crew
7.8Boarding
7.4Comfort
6.9Food
6.8Entertainment
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

I had bad experiences before now was excellent I am glad they have business class again

I upgraded to businesses class. Because of that the flight was comfortable.

Provide free food and drinks on an international flight. Add updated head rests

We waited for one hour to deboard the plane after landing. That could be better

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Worst airline , charge for everything even for water, seat space is very bad

Poor In food , poor in entertainment , passengers don’t get for free not even water

The flight was late olmost 3 hours , they send me to Cartagena … I suppose be in CR at 9 am , I fluid to Costa Rica at 5 pm …

They could offer free food and drink like other international flights.

Everything you need to know for your flight from Santo Domingo to Panama City

Information on your arrival and departure airports