SDQ - PTY

$258 Find Cheap Flights from Santo Domingo to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Panama City departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$461
Typical prices: $575-$479
Avianca
Wed 9/9Sun 9/13
SDQ - PTY • 1 stop
Cheapest non-stop
$507
Typical prices: $656-$521
Copa Airlines
Mon 7/20Thu 7/23
SDQ - PTY • Non-stop
Top airlines
Cheapest • from $461 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Copa Airlines. Average duration is 2h 35m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 96% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $447 (round-trip)
Shortest trip • 7h 02m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 29% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 11% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Panama City (SDQ-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Panama City

Wed, Sep 9 - Sun, Sep 13
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
5:55 pm - 11:50 am
PTY
-
SDQ
16h 55m
1 stop
$461Avianca
Tue, Aug 11 - Tue, Aug 18
Multiple Airlines Logo
4:00 pm - 10:30 am
SDQ
-
PTY
19h 30m
2 stops
Multiple Airlines Logo
3:10 pm - 11:50 am
PTY
-
SDQ
19h 40m
1 stop
$474Multiple Airlines
Mon, Jul 20 - Thu, Jul 23
Copa Airlines Logo
12:13 pm - 1:45 pm
SDQ
-
PTY
2h 32mnonstop
Copa Airlines Logo
12:44 pm - 4:15 pm
PTY
-
SDQ
2h 31mnonstop
$507Copa Airlines
Thu, Aug 6 - Mon, Aug 10
Multiple Airlines Logo
7:45 am - 12:35 am
SDQ
-
PTY
17h 50m
2 stops
Multiple Airlines Logo
3:10 pm - 11:50 am
PTY
-
SDQ
19h 40m
1 stop
$534Multiple Airlines
Thu, Jun 25 - Mon, Jun 29
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
10:10 am - 5:55 pm
PTY
-
SDQ
6h 45m
1 stop
$542Avianca
Wed, Jul 22 - Fri, Jul 31
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 5:55 pm
PTY
-
SDQ
12h 30m
1 stop
$548Avianca
Tue, Jun 30 - Thu, Jul 2
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
4:25 am - 11:50 am
PTY
-
SDQ
6h 25m
1 stop
$552Avianca
Wed, Jun 24 - Sat, Jun 27
Avianca Logo
12:45 pm - 12:35 am
SDQ
-
PTY
12h 50m
1 stop
Avianca Logo
10:10 am - 5:55 pm
PTY
-
SDQ
6h 45m
1 stop
$558Avianca
Mon, Jul 20 - Thu, Jul 23
Avianca Logo
6:50 pm - 9:15 am
SDQ
-
PTY
15h 25m
1 stop
Avianca Logo
5:55 pm - 11:50 am
PTY
-
SDQ
16h 55m
1 stop
$561Avianca
Fri, Aug 21 - Sun, Aug 23
Copa Airlines Logo
12:13 pm - 1:45 pm
SDQ
-
PTY
2h 32mnonstop
Copa Airlines Logo
12:44 pm - 4:15 pm
PTY
-
SDQ
2h 31mnonstop
$564Copa Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to Panama City flights

Get data-powered insights and trends into flights from Santo Domingo to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Panama City departing in September.

What’s the cheapest day of the week to fly from Santo Domingo to Panama City?

The average price of all round-trip flights from Santo Domingo to Panama City clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santo Domingo to Panama City, look for departures on Thursdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama City, Wednesday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Santo Domingo to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Panama City is August, where tickets cost $479 (return) on average. On the other hand, the most expensive months are March and April, where the average cost of round-trip tickets is $599 and $580 respectively.

Can I save money by flying with a layover from Santo Domingo to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $608, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santo Domingo to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Panama City, you should book around 3 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$258
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from Santo Domingo to Panama City

When to book flights from Santo Domingo to Panama City

Are your dates flexible? Find out the best times to travel from Santo Domingo to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Panama City

  • What is the cheapest flight from Santo Domingo to Panama City?

    In the last 5 days, the lowest price for a flight from Santo Domingo to Panama City was $258 for a one-way ticket and $461 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Panama City?

    Yes

  • Which airports will I be using when flying from Santo Domingo to Panama City?

    When flying out of Santo Domingo you will be using Santo Domingo Las Americas. You will be landing at Panama City, also known as Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Santo Domingo to Panama City?

    American Airlines, JetBlue, and Delta offer inflight Wi-Fi service on the Santo Domingo to Panama City flight route.

  • Which aircraft models fly most regularly from Santo Domingo to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Santo Domingo to Panama City flight route.

  • Which airline alliances offer flights from Santo Domingo to Panama City?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Panama City.

  • On which days can I fly direct from Santo Domingo to Panama City?

    There are nonstop flights from Santo Domingo to Panama City on a daily basis.

  • Which is the best airline for flights from Santo Domingo to Panama City, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Panama City are Copa Airlines and Avianca. With an average price for the route of $550 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $387 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Santo Domingo to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santo Domingo to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $265 or less one-way and $390 or less round-trip.

Prefer to fly direct from Santo Domingo to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santo Domingo Las Americas to Panama City Tocumen Intl.
Find which airlines fly direct from Santo Domingo Las Americas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Santo Domingo Las Americas to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Santo Domingo Las Americas

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Santo Domingo to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1568 reviews
7.4Comfort
6.9Food
6.8Entertainment
7.7Boarding
8.1Crew
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

The airline did not allow enough time for the Columbia checkpoint

Seats are absolutely not comfortable and large enough. There’s a limit and you stepped over it. I understand that there’s a business class, however for the price it costs, it’s just plain stupid for a 50 minute flight.

The crew was great! They waited for me as Air Canada flight was delayed by 1:15 hours from Ottawa to Toronto. I am a bit disappointed that we could only use wifi for entertainment but I survived! The only thing I would of liked is a more comfortable seat. The seat cushions are not thick enough for flights longer than 3 hours. Aside from that, everything was great.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

I had bad experiences before now was excellent I am glad they have business class again

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

only a bag of chips and a bottle of water in business class was served

Everything you need to know for your flight from Santo Domingo to Panama City

Information on your arrival and departure airports