PTY - GRU

$279 Find Cheap Flights from Panama City to Sao Paulo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Sao Paulo departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sao Paulo Guarulhos Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Sao Paulo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Sao Paulo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$442
Typical prices: $435-$533
Avianca
Mon 5/4Wed 5/6
PTY - GRU • 1 stop
Cheapest non-stop
$455
Typical prices: $458-$546
Copa Airlines
Thu 5/7Sun 5/10
PTY - GRU • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Emirates' economy class offers 33-inch legroom.
Emirates provides Wi-Fi free for Skywards members.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Avianca
Cheapest • from $442 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Every day
You can fly direct with Copa Airlines. Average duration is 6h 59m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
When to book
4 weeks
in advance
Our data shows that travelers who book at least 4 weeks in advance save around 38% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 15% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sao Paulo!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to Sao Paulo (PTY-GRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Sao Paulo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Sao Paulo

Mon, May 4 - Wed, May 6
Avianca Logo
10:10 am - 10:30 pm
PTY
-
GRU
10h 20m
1 stop
Avianca Logo
7:35 am - 2:15 pm
GRU
-
PTY
8h 40m
1 stop
$442Avianca
Sun, May 3 - Tue, May 19
Avianca Logo
3:05 am - 10:30 pm
PTY
-
GRU
17h 25m
1 stop
Avianca Logo
5:15 pm - 9:15 am
GRU
-
PTY
18h 00m
1 stop
$445Avianca
Tue, Apr 21 - Tue, Apr 28
Copa Airlines Logo
3:12 pm - 12:10 am
PTY
-
GRU
6h 58mnonstop
Copa Airlines Logo
5:25 am - 10:11 am
GRU
-
PTY
6h 46mnonstop
$455Copa Airlines
Mon, May 4 - Fri, May 22
Avianca Logo
10:10 am - 10:30 pm
PTY
-
GRU
10h 20m
1 stop
Avianca Logo
7:35 am - 2:15 pm
GRU
-
PTY
8h 40m
1 stop
$462Avianca
Tue, Apr 28 - Sun, May 3
Multiple Airlines Logo
3:10 pm - 10:30 pm
PTY
-
GRU
29h 20m
1 stop
Multiple Airlines Logo
7:35 am - 9:15 am
GRU
-
PTY
27h 40m
1 stop
$463Multiple Airlines
Tue, May 5 - Fri, May 8
Multiple Airlines Logo
10:10 am - 10:30 pm
PTY
-
GRU
10h 20m
1 stop
Multiple Airlines Logo
7:35 am - 1:05 am
GRU
-
PTY
19h 30m
1 stop
$467Multiple Airlines
Mon, May 4 - Fri, May 8
Avianca Logo
3:05 am - 4:05 pm
PTY
-
GRU
11h 00m
1 stop
Avianca Logo
7:35 am - 2:15 pm
GRU
-
PTY
8h 40m
1 stop
$469Avianca
Sun, Apr 19 - Mon, Apr 20
Copa Airlines Logo
3:32 pm - 12:30 am
PTY
-
GRU
6h 58mnonstop
Copa Airlines Logo
11:10 am - 4:01 pm
GRU
-
PTY
6h 51mnonstop
$471Copa Airlines
Mon, May 4 - Tue, May 19
Avianca Logo
10:10 am - 10:30 pm
PTY
-
GRU
10h 20m
1 stop
Avianca Logo
5:15 pm - 1:05 am
GRU
-
PTY
9h 50m
1 stop
$472Avianca
Sat, May 16 - Tue, May 26
Avianca Logo
3:05 am - 10:30 pm
PTY
-
GRU
17h 25m
1 stop
Avianca Logo
7:35 am - 5:00 pm
GRU
-
PTY
11h 25m
1 stop
$475Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Sao Paulo flights

Get data-powered insights and trends into flights from Panama City to Sao Paulo to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to Sao Paulo Guarulhos Intl Airport?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to Sao Paulo Guarulhos Intl Airport departing in May.

What’s the cheapest day of the week to fly from Panama City to Sao Paulo?

The average price of all round-trip flights from Panama City to Sao Paulo Guarulhos Intl Airport clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to Sao Paulo, you should consider leaving on a Wednesday and avoid Sundays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Mondays and the most expensive ones on Saturdays.

What is the cheapest month to fly from Panama City to Sao Paulo Guarulhos Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Sao Paulo Guarulhos Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Sao Paulo Guarulhos Intl Airport is August, where tickets cost $402 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $612 and $515 respectively.

Can I save money by flying with a layover from Panama City to Sao Paulo Guarulhos Intl Airport?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $442, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Panama City to Sao Paulo Guarulhos Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Sao Paulo Guarulhos Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Sao Paulo Guarulhos Intl Airport, you should book around 4 weeks before departure, which saves you about 38% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Sao Paulo

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Duncan Madden

Duncan Madden

Expert on Emirates

Duncan is a freelance travel writer, copywriter and book author in constant search of travel stories and the perpetual sensation of being on holiday. He’s never happier than when on a dusty trail in search of empty waves or ducking under the piste tape in search of snowbound solitude. British born, living in Germany, but happiest heading for the horizon. His first book, Found in Translation, explores the etymologies and stories of country names around the world and is out now.

Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Good to know

Low seasonJuly
Cheapest flight$279
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Panama City to Sao Paulo

When to book flights from Panama City to Sao Paulo

Are your dates flexible? Find out the best times to travel from Panama City to Sao Paulo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Panama City to Sao Paulo flights

  • What is the cheapest flight from Panama City to Sao Paulo Guarulhos Intl Airport?

    In the last 3 days, the lowest price for a flight from Panama City to Sao Paulo Guarulhos Intl Airport was $279 for a one-way ticket and $442 for a round-trip.

  • Do I need a passport to fly between Panama City and Sao Paulo?

    A passport is required to fly from Panama City to Sao Paulo.

  • Which airports will I be using when flying from Panama City to Sao Paulo?

    Panama City airport is called Panama City Tocumen Intl and the only airport in Sao Paulo is Sao Paulo Guarulhos Intl.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Sao Paulo?

    American Airlines, and Delta offer inflight Wi-Fi service on the Panama City to Sao Paulo flight route.

  • Which aircraft models fly most regularly from Panama City to Sao Paulo?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to Sao Paulo flight route.

  • Which airline alliances offer flights from Panama City to Sao Paulo?

    Star Alliance is the only airline alliance operating flights between Panama City and Sao Paulo.

  • On which days can I fly direct from Panama City to Sao Paulo?

    There are nonstop flights from Panama City to Sao Paulo on a daily basis.

  • Which is the best airline for flights from Panama City to Sao Paulo, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Panama City to Sao Paulo are Copa Airlines and Avianca. With an average price for the route of $511 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $488 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Panama City to Sao Paulo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Sao Paulo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Sao Paulo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sao Paulo from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Sao Paulo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sao Paulo with an airline and back to Panama City with another airline. Booking your flights between Panama City and GRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Sao Paulo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sao Paulo from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Sao Paulo Guarulhos Intl Airport

  • Looking for a cheap flight? 25% of our users found flights on this route for $335 or less one-way and $391 or less round-trip.

Prefer to fly direct from Panama City to Sao Paulo?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Sao Paulo Guarulhos Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Sao Paulo Guarulhos Intl to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to Sao Paulo

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Sao Paulo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Sao Paulo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1557 reviews
6.8Food
8.1Crew
7.8Boarding
7.4Comfort
6.8Entertainment
Airline reviews

Flight got delayed; had to go through security three times.

2.0 MediocreAnonymous, Feb 2026
PTY - JFK
Read more Copa Airlines reviews

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

Everything you need to know for your flight from Panama City to Sao Paulo

Information on your arrival and departure airports