$218 Find Cheap Flights from Portland to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Portland to South America departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Portland to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$566
Bogotá
Bogotá2 stops$601
Buenos Aires
Buenos Aires1 stop$1,037
Rio de Janeiro
Rio de Janeiro2 stops$890
Santiago
Santiago2 stops$980
Cartagena
Cartagena2 stops$715
Quito
Quito1 stop$525
Guayaquil
Guayaquil1 stop$492
Cali
Cali2 stops$763
Cusco
Cusco2 stops$969
Georgetown
Georgetown2 stops$829
Montevideo
Montevideo2 stops$1,103
Asuncion
Asuncion2 stops$1,481
Lima
Lima2 stops$566
Bogotá
Bogotá2 stops$601
Buenos Aires
Buenos Aires1 stop$1,037
Rio de Janeiro
Rio de Janeiro2 stops$890
Santiago
Santiago2 stops$980
Cartagena
Cartagena2 stops$715
Quito
Quito1 stop$525
Guayaquil
Guayaquil1 stop$492
Cali
Cali2 stops$763
Cusco
Cusco2 stops$969
Georgetown
Georgetown2 stops$829
Montevideo
Montevideo2 stops$1,103
Asuncion
Asuncion2 stops$1,481

Book Cheap Portland to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Portland to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Portland to South America

Sun, Apr 26 - Tue, May 12
Multiple Airlines Logo
7:05 am - 7:45 am
PDX
-
GYE
22h 40m
1 stop
Multiple Airlines Logo
4:05 pm - 1:10 pm
GYE
-
PDX
23h 05m
1 stop
$492Multiple Airlines
Sun, Apr 26 - Tue, May 12
Multiple Airlines Logo
7:05 am - 10:40 am
PDX
-
GYE
25h 35m
1 stop
Multiple Airlines Logo
4:05 pm - 1:10 pm
GYE
-
PDX
23h 05m
1 stop
$494Multiple Airlines
Sun, Aug 16 - Wed, Aug 26
American Airlines Logo
7:45 am - 11:35 pm
PDX
-
MDE
13h 50m
2 stops
American Airlines Logo
6:00 am - 8:52 pm
MDE
-
PDX
16h 52m
2 stops
$751American Airlines
Fri, Jul 3 - Fri, Jul 10
American Airlines Logo
6:15 am - 11:58 pm
PDX
-
MDE
15h 43m
2 stops
American Airlines Logo
6:00 am - 11:21 pm
MDE
-
PDX
19h 21m
2 stops
$761American Airlines
Wed, Aug 12 - Wed, Aug 26
LATAM Airlines Logo
5:10 pm - 5:25 pm
PDX
-
SCL
21h 15m
2 stops
LATAM Airlines Logo
7:55 pm - 12:13 pm
SCL
-
PDX
19h 18m
2 stops
$980LATAM Airlines
Wed, Aug 12 - Wed, Aug 26
LATAM Airlines Logo
5:10 pm - 5:25 pm
PDX
-
SCL
21h 15m
2 stops
LATAM Airlines Logo
6:45 pm - 12:13 pm
SCL
-
PDX
20h 28m
2 stops
$997LATAM Airlines
Wed, May 6 - Wed, May 13
United Airlines Logo
7:00 am - 8:00 am
PDX
-
EZE
21h 00m
1 stop
United Airlines Logo
9:00 pm - 7:38 pm
EZE
-
PDX
26h 38m
1 stop
$1,037United Airlines
Wed, May 6 - Wed, May 13
United Airlines Logo
5:20 am - 8:00 am
PDX
-
EZE
22h 40m
3 stops
United Airlines Logo
9:00 pm - 8:58 pm
EZE
-
PDX
27h 58m
2 stops
$1,041United Airlines
Tue, Apr 21 - Wed, Apr 29
Delta Logo
11:51 am - 4:00 pm
PDX
-
AEP
24h 09m
2 stops
Delta Logo
3:45 pm - 10:16 pm
AEP
-
PDX
34h 31m
2 stops
$1,127Delta
Tue, Apr 21 - Wed, Apr 29
Delta Logo
11:51 am - 9:45 am
PDX
-
EZE
17h 54m
1 stop
Delta Logo
1:10 pm - 3:38 pm
EZE
-
PDX
30h 28m
2 stops
$1,131Delta
Booking Insights

KAYAK's insights & trends for Portland to South America flights

Get data-powered insights and trends into flights from Portland to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Portland to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Portland to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Portland to South America is February, when tickets cost $790 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $1,156 and $1,116 respectively.

How far in advance should I book a flight from Portland to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Portland to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Portland to South America, you should book around 4 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$218
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from Portland to Guayaquil

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Portland to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Portland to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Portland to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Portland to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Portland to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Portland to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Portland to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Portland to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Portland to South America

 
Need help choosing which airline to fly with from Portland to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8341 reviews
7.9Comfort
7.2Food
7.8Entertainment
8.5Crew
8.1Boarding
Airline reviews

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

2.0 MediocreAliya, Mar 2026
JFK - ATL
Read more Delta reviews

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

It was fine. 55 minute flight. No snacks or beverage service offered. Boarding went smoothly and my walker was waiting for me on the jet way.

Smaller plane for a longer flight than my first one. Doesn’t make sense.

The cabin temperature was nice and cool. The wifi was not working.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We were not allowed to carry a bottle of water onto the 8 hour flight.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

The flight was late. Please do not delay next time.

They promise free wi-fi prior to boarding and then once on board you are informed you have to purchase wifi even after being a mileagePlus member.

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

Awful. No counter attendants. No dinner offered due to delays.

Horrible service no Wi-Fi connection on both leg of the flight and they are refusing to fix bad service

3 hour delay…. Nearly 2 hours sitting on tarmac. Do better, United. Or at least have the sense to not say “we hope you enjoyed your flight with us” upon disembarking.

Flights were on time. Free Wifi on plane. Everything was well organized.

During landing. 2 crew members passed 3 times by my lane and didn't notice that people in front of us had their site to the furthermore reclined... That was uncomfortable and could have been dangerous.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

The flight changed gates multiple times and flight had to be delayed multiple times

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Tv screens and movie selection v good. Friendly staff. They were really worried about max capacity and room for carryons. That is never fun but i had no problem finding space when I boarded.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

My flight from LGA was cancelled and my rebooked flight from JFK was delayed numerous times. I will now be getting home after 2am.

Flight was delayed half hour before boarding, but when I checked flight aware the plane that would Pick us up had a delay of more than an hour. AA should let us know in advance to avoid waiting several hours in the airport

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The flight attendant in business class was excellent! Professional, friendly and attentive.

Everything you need to know for your flight to South America

Information on your arrival and departure airports