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UIO - SCL

$193 Find Cheap Flights from Quito to Santiago - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$339
Typical prices: $428-$585
JetSMART
Sun 11/18Fri 11/23
UIO - SCL • 1 stop
Cheapest non-stop
$391
Typical prices: $576-$685
LATAM Airlines
Wed 1/10Wed 2/14
UIO - SCL • Non-stop
Nonstop flights
Not available
There are currently no direct flights between Quito and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 28% compared to booking last minute.
Insights
Insights
When to travel
November
Cheapest • 9% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Lima J Chavez Intl (LIM)
Cheapest • Avg $476 (round-trip)
Guayaquil Jose Joaquin de Olmedo (GYE)
Shortest trip • 8h 27m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Quito to Santiago (UIO-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Quito to Santiago

Wed, Nov 18 - Mon, Nov 23
JetSMART Logo
4:50 pm - 5:05 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 am - 4:05 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 58m1 stop Lima J Chavez Intl
$339JetSMART
Fri, Nov 6 - Fri, Nov 13
JetSMART Logo
4:50 pm - 5:05 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
JetSMART Logo
6:07 am - 4:05 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 58m1 stop Lima J Chavez Intl
$342JetSMART
Wed, Nov 11 - Thu, Nov 12
Multiple Airlines Logo
4:50 pm - 5:05 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
10h 15m1 stop Lima J Chavez Intl
Multiple Airlines Logo
8:13 am - 11:00 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
16h 47m1 stop Bogotá El Dorado
$364Multiple Airlines
Fri, Nov 20 - Fri, Nov 27
Multiple Airlines Logo
6:40 pm - 3:48 pmUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
19h 08m1 stop Bogotá El Dorado
Multiple Airlines Logo
6:07 am - 4:05 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
11h 58m1 stop Lima J Chavez Intl
$376Multiple Airlines
Tue, Nov 3 - Fri, Nov 6
Avianca Logo
6:30 am - 1:05 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
16h 35m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado
Avianca Logo
4:15 pm - 1:10 amSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
10h 55m1 stop Bogotá El Dorado
$380Avianca
Wed, Oct 28 - Wed, Nov 18
Avianca Logo
11:25 am - 5:45 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
16h 20m2 stops Guayaquil Jose Joaquin de Olmedo Bogotá El Dorado
Avianca Logo
4:15 pm - 1:10 amSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
10h 55m1 stop Bogotá El Dorado
$380Avianca
Sun, Jan 10 - Sun, Feb 14
LATAM Airlines Logo
11:00 pm - 6:00 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
5h 00mnonstop
LATAM Airlines Logo
5:55 pm - 1:55 amSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
10h 00m1 stop Lima J Chavez Intl
$391LATAM Airlines
Sun, Jan 10 - Sun, Feb 21
LATAM Airlines Logo
11:00 pm - 6:00 amUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
5h 00mnonstop
LATAM Airlines Logo
7:00 pm - 9:45 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
4h 45mnonstop
$391LATAM Airlines
Sat, Mar 13 - Mon, Mar 29
Copa Airlines Logo
6:26 pm - 10:38 pmUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
26h 12m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:06 pm - 9:25 amSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
19h 19m1 stop Panama City Tocumen Intl
$483Copa Airlines
Sat, Dec 5 - Fri, Dec 18
Copa Airlines Logo
6:32 pm - 8:11 pmUIO  Quito Mariscal Sucr-SCL Santiago Arturo Merino Benitez
23h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:48 am - 12:36 pmSCL  Santiago Arturo Merino Benitez-UIO Quito Mariscal Sucr
10h 48m1 stop Panama City Tocumen Intl
$606Copa Airlines
Booking Insights

Price, demand and travel trends for Quito to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Quito to Santiago?

Round-trip flights from Quito to Santiago typically range from $428 to $585. The lowest price found in the past 5 days was $339, on JetSMART.

What's the cheapest day of the week to fly from Quito to Santiago?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Quito to Santiago. It’s 9% cheaper than the average day, while Saturday is the most expensive, with prices 10% higher.

What’s the cheapest month to fly from Quito to Santiago?

•November is the cheapest month to fly from Quito to Santiago at $463 round-trip.
•February ($585) and December ($546) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 26% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Quito to Santiago the cheapest?

Flights from Quito to Santiago are cheapest 7 weeks before departure. Booking in this window typically costs about 28% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Quito to Santiago flights

Low season

June

Cheapest flight

$193
Beat the crowds with an average 36% drop in travelers.
The most popular month to fly with an average 8% increase in travelers.
One-way flight from Quito to Santiago

When to book flights from Quito to Santiago

Are your dates flexible? Find out the best times to travel from Quito to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Quito to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Quito to Santiago?

    These are the earliest and latest flight times available from Quito to Santiago:

    • Earliest: departs at 11:00 pm and lands at 4:00 am
    • Latest: departs at 11:00 pm and lands at 4:00 am.

    The flight takes about 5h.

  • What cabin classes can I book on flights from Quito to Santiago?

    Two cabin classes are available on flights from Quito to Santiago:

    • Economy Class
    • Business Class

  • How long is a flight from Quito to Santiago?

    A nonstop flight from Quito to Santiago takes 5h, covering 2,349 miles.

  • Do I need a passport to fly from Quito to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Quito to Santiago flight?

    Round-trip flights from Quito to Santiago range from $428 to $585, with an average of $511 over the past 12 months. Anything below $428 counts as a good deal.

  • How expensive are last-minute Quito to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 16% above the $511 route average. Book 7 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Quito to Santiago?

    On this route, layover flights are cheaper than nonstop options on average. Layover fares average $476 round-trip via Lima J Chavez Intl (LIM), compared to $635 for nonstop.

  • What is the standard checked-bag allowance on flights from Quito to Santiago?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $60–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Have flight prices from Quito to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $339 to $1,190. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Quito to Santiago looking right now?

    One-way fares from Quito to Santiago are currently lower than usual. Average one-way flight prices are about $273, which is 12% below the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Quito to Santiago?

    Flights from Quito to Santiago usually depart from Quito Mariscal Sucr (UIO) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Quito to Santiago pass through?

    One-stop flights from Quito to Santiago most commonly connect through:

    • Lima J Chavez Intl (LIM) - 73% of one-stop connections
    • Bogotá El Dorado (BOG) - 19% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 7% of one-stop connections
    • Guayaquil Jose Joaquin de Olmedo (GYE) - 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Quito to Santiago?

    Yes. Flexible dates can save you up to 18% on flights from Quito to Santiago. Wednesday is the cheapest departure day at $468 round-trip on average, while Saturday is the most expensive at $567, a difference of $99.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Quito to Santiago?

    Only LATAM Airlines operates flights between Quito and Santiago.

  • How much time can I save by choosing a different layover airport from Quito to Santiago?

    Flying via Guayaquil Jose Joaquin de Olmedo (GYE) gives the shortest average 1-stop total travel time at 8h 27m, compared with 10h 05m via Bogotá El Dorado (BOG) and 10h 21m via Panama City Tocumen Intl (PTY).

  • What is the time difference between Quito and Santiago?

    Santiago is 2 hours ahead of Quito (Chile Time vs Ecuador Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

  • Which airlines offer extra legroom and free seat selection on Quito to Santiago flights?

    Among airlines operating Quito to Santiago flights:

    • LATAM Airlines: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Quito to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • LATAM Airlines: a cabin bag and a checked bag in Economy Class

    Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.

Your guide to booking Quito to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Saturday. On this route, Wednesday flights average $468, about $99 less than Saturday fares (17% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 28% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Quito to Santiago trip for November. Fares historically average $463 round-trip in that month - typically $122 less than the most expensive month, which is February (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Lima J Chavez Intl Airport (LIM) can be cheaper than flying direct. The cheapest layover option averages $476 round-trip on this route - about $158 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Quito to Santiago?

 
Find which airlines fly direct from Quito Mariscal Sucr Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Quito Mariscal Sucr to Santiago Arturo Merino Benitez

Tuesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Quito Mariscal Sucr

Tuesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

More options for your flight from Quito to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
Vacations in Santiago