- Argentina (Español)
- Australia (English)
- Österreich (Deutsch)
- Belgique (Français)
- België (Nederlands)
- Bolivia (Español)
- Brasil (Português)
- Canada (English)
- Canada (Français)
- Chile (Español)
- Colombia (Español)
- Costa Rica (Español)
- Česká republika (Čeština)
- Danmark (Dansk)
- Deutschland (Deutsch)
- Germany (English)
- Ecuador (Español)
- El Salvador (Español)
- España (Español)
- Espanya (Català)
- France (Français)
- Ελλάδα (Ελληνική)
- Guatemala (Español)
- Honduras (Español)
- Hong Kong (English)
- 香港 (中文)
- India (English)
- Indonesia (Bahasa Indonesia)
- Indonesia (English)
- Ireland (English)
- Israel (English)
- ישראל (עִבְרִית)
- Italia (Italiano)
- 日本 (日本語)
- Malaysia (English)
- Malaysia (Melayu)
- México (Español)
- Nederland (Nederlands)
- New Zealand (English)
- Nicaragua (Español)
- Norge (Norsk)
- Panamá (Español)
- Paraguay (Español)
- Perú (Español)
- Philippines (English)
- Polska (Polski)
- Portugal (Português)
- Puerto Rico (Español)
- República Dominicana (Español)
- România (Română)
- المملكة العربية السعودية (العَرَبِيَّة)
- Saudi Arabia (English)
- Suisse (Français)
- Schweiz (Deutsch)
- Singapore (English)
- South Africa (English)
- 대한민국 (한국어)
- Suomi (Suomi)
- Sverige (Svenska)
- 台灣 (中文)
- ประเทศไทย (ภาษาไทย)
- Thailand (English)
- Türkiye (Türkçe)
- Україна (Українська)
- United Arab Emirates (English)
- United Kingdom (English)
- United States (English)
- Estados Unidos (Español)
- Uruguay (Español)
- Venezuela (Español)
- Vietnam (English)
- Việt Nam (Việt)

Flight Deals
Booking Insights
KAYAK's insights & trends for Roanoke to Florida Keys flights
Get data-powered insights and trends into flights from Roanoke to Florida Keys to help you find the cheapest flights, the best time to fly and much more.
Can I save money by flying with a layover from Roanoke to Florida Keys?
The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.
No, with an average price for the route of $442, prices are generally cheapest when you fly direct.
What is the cheapest month to fly from Roanoke to Florida Keys?
To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Roanoke to Florida Keys, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Roanoke to Florida Keys is July, when tickets cost $399 (return) on average. On the other hand, the most expensive months are March and May, when the average cost of round-trip tickets is $567 and $516 respectively.
Good to know
Low season | December |
|---|---|
High season | January |
FAQs - booking Florida Keys flights
Reviews of the top 3 airlines serving from Roanoke to Florida Keys
See real verified KAYAK customer reviews for airlines flying from Roanoke to Florida Keys. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
7.8
DeltaOverall score based on 8692 reviews
7.2Food
7.8Comfort
8.1Boarding
8.5Crew
7.8Entertainment
Airline reviews
Flight attendent didn't let me sit in the empty window seat literally next to me. Doors had closed already so I moved over. She came over, asked for my ticket and made me switch back to the middle. The man on the aisle and I were right on top of each other. Seemed like a real power trip for no reason at all.
10.0 ExcellentErin, Oct 2026
Flight attendent didn't let me sit in the empty window seat literally next to me. Doors had closed already so I moved over. She came over, asked for my ticket and made me switch back to the middle. The man on the aisle and I were right on top of each other. Seemed like a real power trip for no reason at all.
Good but since we got in early we had to wait on runway for our gate. That was kind of a bummer but we still got in earlier than planned For entertainment I was watching a movie and getting close to the end of it with 15 min left but it kept jumping automatically to the next movie before finishing.
Delta seems to be getting worse. They are trying to take any comfort away from poorer people to make more money selling it to the rich. I paid for delta comfort and on my flight from Rome to jfk I had a tv that would go on and off automatically and literally no electrical outlets or usbs worked which was advertised in the price of the fare. The infotainment system wasn’t fully working. Luckily the movies worked and the plane was needing a lot of repairs. The jfk to Tampa flight they stuck me next to this really larger guy who was half in my seat and they should have made other accommodations for him because now you’re interfering with the fare class I paid for and act like I shouldn’t care because I didn’t pay for first class. I couldn’t even pull out my tray table because of this guy. The safety video tv screen you couldn’t even see it. It made me a little scared to fly delta anymore, because if these planes are this much in need of servicing, I have to wonder if the plane is going to make it to the destination.
Late flight, screens not working and still had to pay for a drink
They changed my seat assignment from window to middle. I have a physical need to sit by the window because of spinal issues. I unboarded in pain, I also was placed between 2 very large men. I am very disappointed and now dealing with the physical aftermath.
The crew were awesome and ready to help as much as possible. The gate agent in Atlanta was tremendously helpful. The delays were ridiculous. Getting home at 4am when I could have driven home faster was unimpressive. Being delayed for countless hours through the night wasn't a great travel experience.
We sat at the gate for over 30 minutes, with no indication as to why
Flight Staff: Always great! Checking back vs carry-on: I typically check my bag since so much time is spent stowing the bag, it's heavy, maybe not enough room. Delta is charging $45 to check bags. Yet, the people who have multiple carry-on bags are then asked to check their bags and are offered this service for free. This does not seem fair to a person who is trying to be proactive in improving the process . Boarding: Boarding is always slow and exhausting. With the exception of First Class, Economy, why not board the zone in the back of the plane first??? Seats: Why cross the seat belts? I get that it looks nice, but people waste so much time moving them or sitting on them and then having to move. Seats: On both my flights the seat did not recline. Not a big deal. Smell: There was a horrific smell like the restrooms on my first flight. I thought I was going to be sick. Most flights do not smell great. Does Delta use air purifiers or anything?
DL482 did not wait for about 10 of us including a mother and 3 children when we were in the same terminal on DL486, where we were switching from waiting for a jet bridge fix, to moving to a neighboring gate. I understand taxiing delays are ok either but man. We only needed 5 more minutes. DL482 did not adjust from their times at all. This was my first time with Delta.
The actual flight was smooth and we arrived earlier than expected which was great. The flight attendants gave unclear instructions and were rude. They seemed overwhelmed or flustered for the flight. Inflight service was delayed and unsure why.
It was good flight was smooth, little cold on the plane but other wise good.
It was great. I really love the app. User friendly and very comprehensive when it comes to having information at my fingertips tips related my travel.
The experience with United Airlines was excellent; however, the experience with Houston Intercontinental Airport (IAH) was horrible. Although our flight departed from Terminal B, we had to go through security in Terminal C and then get on a train for travel to Terminal B. Additionally, there was significant walking required to get to the boarding location.
Flight was delayed 5 hours. Updates kept changing. Sears were extremely cramped. Very little leg room. Flight attendant was rushing through with drinks and hit me in the knee either the cart and didn’t apologize. They gave a 15 dollar voucher in airport which doesn’t buy. Much and it was so late that choices were limited.
Always pretty good as far as I see it. Staff was friendly and process was quick to get on and off.
The flight was delayed because they closed several flight ways because of air shows, fire works, etc.
Lost one piece of luggage even though I checked in 2.5 hours before the flight
Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms
We were a little disappointed to not be able to complete check in online without uploading pics of passports. Also we have KTN's and they weren't on our boarding passes when we got to security. Had to trek back to counter to have them fix.
Left an hour and a half after the listed time. Up side was it had TV screens on the seat.
Flight attendant super rude demanding I remove my carry on baggage from overhead and place under seat. I stated I am an ADA passenger and need the leg room as the seats are very tight. That’s why I boarded early for the extra time to get situated. She said, we need the space. I replied “How can that be as only a few passengers have boarded so far? I am executive platinum status so I understand the rules and you are discriminating against ADA federal law. Please stop”. Her answer… then you should find another flight! Not ok. Addressed with senior flight attendant. So unprofessional and discriminatory.
Good flight, excellent personnel; poor comfort, small seats, big cost.
What an amazing plane! We flew a 787 to Miami. Although the Internet was not functioning, it was a wonderful flight.
It was freezing in the cabin. That's on me to be better prepared in the future.
I have posted the comments in the first flight leg.
When we landed, there was only one gate agent to handle three planes, including retrieval of carry on luggage. I was stuck in the jet way waiting on my carry on for almost 20-30 minutes. NOT GOOD
Horrible - their gate agents do not care and loyalty means nothing to them. Planes are often late and you are left on your own. Oh, and WiFi - good luck!
Flight was delayed for 5 hours in ten minute increments. Bizarre and frustrating
Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.
Both flights were delayed. One by an hour and the other by 1 1/2 hours after boarding.
More options for your flight to Florida Keys
Complete your trip to Florida Keys with a hotel stay or car rental
Information on your arrival and departure airports
Cabin class types available on flights to Roanoke
Cabin classes available on flights to Florida Keys. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from domestic origins to Roanoke
Flights from all regions of Roanoke to Florida Keys. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights to other popular destinations
The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.
Flights from Roanoke to popular cities in Florida Keys
Flights from Roanoke to Key Westfrom $364
Flights from Roanoke to Miamifrom $359