$289 Find Cheap Flights from Roanoke to Mississippi

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to Mississippi departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
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Cheap Flights from Roanoke to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$337
Columbus
Columbus2 stops$847
Memphis
Memphis1 stop$289
Jackson
Jackson1 stop$337
Columbus
Columbus2 stops$847
Memphis
Memphis1 stop$289

Book Cheap Roanoke to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to Mississippi

Wed, Apr 29 - Sat, May 2
Delta Logo
6:00 am - 11:12 am
ROA
-
MEM
6h 12m
1 stop
Delta Logo
5:59 pm - 12:25 am
MEM
-
ROA
5h 26m
1 stop
$289Delta
Fri, Apr 10 - Sun, Apr 12
Delta Logo
7:51 pm - 11:24 pm
ROA
-
MEM
4h 33m
1 stop
Delta Logo
7:33 pm - 12:04 am
MEM
-
ROA
3h 31m
1 stop
$309Delta
Mon, Apr 6 - Tue, Apr 28
American Airlines Logo
8:00 pm - 11:51 pm
ROA
-
MOB
4h 51m
1 stop
American Airlines Logo
5:45 pm - 10:56 pm
MOB
-
ROA
4h 11m
1 stop
$309American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
8:09 am - 2:23 pm
ROA
-
MEM
7h 14m
2 stops
American Airlines Logo
3:39 pm - 10:26 pm
MEM
-
ROA
5h 47m
1 stop
$314American Airlines
Fri, Aug 14 - Tue, Aug 18
Delta Logo
6:00 am - 8:24 am
ROA
-
MOB
3h 24m
1 stop
Delta Logo
7:15 pm - 11:50 pm
MOB
-
ROA
3h 35m
1 stop
$319Delta
Sat, Jun 20 - Thu, Jun 25
Delta Logo
6:00 am - 8:30 am
ROA
-
MOB
3h 30m
1 stop
Delta Logo
4:15 pm - 11:49 pm
MOB
-
ROA
6h 34m
1 stop
$328Delta
Thu, Jun 11 - Sun, Jun 14
Delta Logo
6:00 am - 8:30 am
ROA
-
MOB
3h 30m
1 stop
Delta Logo
7:15 pm - 11:49 pm
MOB
-
ROA
3h 34m
1 stop
$329Delta
Mon, Apr 6 - Thu, Apr 9
Multiple Airlines Logo
9:55 pm - 10:15 am
ROA
-
MEM
13h 20m
1 stop
Multiple Airlines Logo
11:14 am - 2:19 pm
MEM
-
ROA
26h 05m
1 stop
$347Multiple Airlines
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
5:45 pm - 10:04 pm
ROA
-
MEM
5h 19m
1 stop
United Airlines Logo
9:50 am - 5:02 pm
MEM
-
ROA
6h 12m
1 stop
$359United Airlines
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
10:34 am - 5:47 pm
ROA
-
MEM
8h 13m
2 stops
United Airlines Logo
2:45 pm - 9:07 pm
MEM
-
ROA
5h 22m
1 stop
$364United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to Mississippi flights

Get data-powered insights and trends into flights from Roanoke to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to Mississippi were found on Delta ($309) and American Airlines ($309).

Good to know

Low seasonApril
Cheapest flight$289
Best time to beat the crowds but there is an average 21% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Roanoke to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Roanoke to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Roanoke to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8291 reviews
8.1Boarding
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
Airline reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

2.0 MediocreSusan, Mar 2026
JAX - ATL
Read more Delta reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

The flight was flying with 30% capacity. The flight my seat from preferred seating to back of the seat. Even though i can understand that this was to balance the flight weight. The flight attendance decided to do the serving near my seat and in the middle , their noices woke me up from sleep , when i realized that the service has ended and when they were going back asked for a coffee, for which they answered they have completed teh service in my location. That really upset me as they woke me up and also rejected the coffee i asked. I ended up landing with a headache, thanks to the crew that screwed up my travel

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

Flights were constantly delayed. CRW took 50 minutes to get bags

Flight has been delayed every time I've ever taken it. Seats uncomfortable. Children behind me yelling the entire flight. Some of this is out of their control but overall just consistently not a great experience.

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

There was no inflight service. Once we landed we were delayed to find a gate for an hour and a half which was 1/2 the total time in the air.

The gate got changed several times and the flight was delayed over an hour. Awful experience

Poor communication ahead of time about flight delays and old planes/other equipment.

The flight was delayed multiple times. I was autobooted and placed in the center seat in the last row of the plane.

Everything you need to know for your flight from Roanoke to Mississippi

Information on your arrival and departure airports