$269 Find Cheap Flights from Roanoke to Mississippi

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to Mississippi departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
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Cheap Flights from Roanoke to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$295
Columbus
Columbus2 stops$690
Memphis
Memphis1 stop$269
Jackson
Jackson1 stop$295
Columbus
Columbus2 stops$690
Memphis
Memphis1 stop$269

Book Cheap Roanoke to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to Mississippi

Wed, Apr 29 - Sat, May 2
Delta Logo
6:00 am - 11:12 am
ROA
-
MEM
6h 12m
1 stop
Delta Logo
9:25 am - 2:47 pm
MEM
-
ROA
4h 22m
1 stop
$269Delta
Fri, Feb 20 - Sat, Feb 28
American Airlines Logo
8:00 pm - 11:51 pm
ROA
-
MEM
4h 51m
1 stop
American Airlines Logo
11:21 am - 6:15 pm
MEM
-
ROA
5h 54m
1 stop
$274American Airlines
Tue, Feb 17 - Sat, Feb 21
Delta Logo
7:59 pm - 10:58 pm
ROA
-
MOB
3h 59m
1 stop
Delta Logo
5:00 pm - 12:06 am
MOB
-
ROA
6h 06m
1 stop
$279Delta
Thu, Apr 2 - Sun, Apr 5
Delta Logo
6:00 am - 10:08 am
ROA
-
JAN
5h 08m
1 stop
Delta Logo
5:35 am - 10:27 am
JAN
-
ROA
3h 52m
1 stop
$295Delta
Wed, Apr 29 - Sat, May 2
American Airlines Logo
8:09 am - 2:23 pm
ROA
-
MEM
7h 14m
2 stops
American Airlines Logo
3:39 pm - 10:26 pm
MEM
-
ROA
5h 47m
1 stop
$308American Airlines
Thu, Feb 12 - Sun, Feb 15
American Airlines Logo
8:00 pm - 11:51 pm
ROA
-
MEM
4h 51m
1 stop
American Airlines Logo
5:00 am - 10:37 am
MEM
-
ROA
4h 37m
1 stop
$309American Airlines
Fri, Feb 20 - Sat, Feb 28
United Airlines Logo
10:15 am - 9:59 pm
ROA
-
MEM
12h 44m
2 stops
United Airlines Logo
7:30 am - 8:07 pm
MEM
-
ROA
11h 37m
2 stops
$310United Airlines
Tue, Feb 17 - Sat, Feb 21
American Airlines Logo
8:15 am - 5:16 pm
ROA
-
MOB
10h 01m
2 stops
American Airlines Logo
6:45 pm - 11:45 pm
MOB
-
ROA
4h 00m
1 stop
$314American Airlines
Fri, Feb 20 - Sat, Feb 28
United Airlines Logo
5:33 pm - 9:59 pm
ROA
-
MEM
5h 26m
1 stop
United Airlines Logo
7:30 am - 8:07 pm
MEM
-
ROA
11h 37m
2 stops
$324United Airlines
Thu, Feb 12 - Sat, Feb 14
United Airlines Logo
6:40 am - 10:57 am
ROA
-
MEM
5h 17m
1 stop
United Airlines Logo
9:55 am - 8:07 pm
MEM
-
ROA
9h 12m
2 stops
$344United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to Mississippi flights

Get data-powered insights and trends into flights from Roanoke to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to Mississippi were found on Delta ($269) and United Airlines ($310).

Good to know

Low seasonApril
Cheapest flight$269
Best time to beat the crowds but there is an average 14% increase in price.
Flight from Roanoke to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Roanoke to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Roanoke to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8132 reviews
7.2Food
8.1Boarding
8.5Crew
7.8Entertainment
7.9Comfort
Airline reviews

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

2.0 MediocreTodd, Jan 2026
IAH - ATL
Read more Delta reviews

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

For a 5 1/2 hour flite i considered the "business class" to be subpar. The seats were just ok, no amenities, really nothing more than a long domestic flight. Frankly disappointed.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

This was one of the most frustrating travel experiences I've had to date. I had changed my flight day of to this one as it was slated to depart on time. It ended up being so delayed that my original flight took off before this one did. The boarding process began but eventually stopped and everyone had to get off the plane as a problem was identified. The person at the front desk just tried to laugh it off as if this wasn't already a huge inconvenience. From there, we eventually got to board only to sit at the gate for an additional hour because of some additional issue. This was extremely frustrating and caused a lot of stress.

Update to handle the delay was very bad, crews no smiles or welcome or thanks. Don’t care attitude

It would be nice to have some low carb options in the snacks.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

Everything you need to know for your flight from Roanoke to Mississippi

Information on your arrival and departure airports