$349 Find Cheap Flights from Roanoke to Mississippi - Compare and Save

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Cheap Flights from Roanoke to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Jackson
Jackson1 stop$349
Columbus
Columbus1 stop$782
Jackson
Jackson1 stop$349
Columbus
Columbus1 stop$782

Book Cheap Roanoke to Mississippi Plane Tickets

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to Mississippi

Mon, May 10 - Sat, May 15
Delta Logo
6:00 am - 11:22 amROA  Roanoke-JAN Jackson-Evers Intl
6h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:35 pm - 12:23 amJAN  Jackson-Evers Intl-ROA Roanoke
5h 48m1 stop Atlanta Hartsfield-Jackson
$349Delta
Fri, Feb 5 - Thu, Feb 11
Delta Logo
6:00 am - 11:28 amROA  Roanoke-JAN Jackson-Evers Intl
6h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 am - 2:43 pmJAN  Jackson-Evers Intl-ROA Roanoke
6h 38m1 stop Atlanta Hartsfield-Jackson
$349Delta
Sat, Feb 6 - Thu, Feb 11
Delta Logo
6:00 am - 11:28 amROA  Roanoke-JAN Jackson-Evers Intl
6h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:05 am - 2:43 pmJAN  Jackson-Evers Intl-ROA Roanoke
6h 38m1 stop Atlanta Hartsfield-Jackson
$349Delta
Sat, Jan 16 - Thu, Jan 21
Delta Logo
6:00 am - 11:28 amROA  Roanoke-JAN Jackson-Evers Intl
6h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:55 pm - 12:16 amJAN  Jackson-Evers Intl-ROA Roanoke
6h 21m1 stop Atlanta Hartsfield-Jackson
$349Delta
Wed, May 12 - Sat, May 15
Delta Logo
6:00 am - 11:22 amROA  Roanoke-JAN Jackson-Evers Intl
6h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:45 am - 2:40 pmJAN  Jackson-Evers Intl-ROA Roanoke
5h 55m1 stop Atlanta Hartsfield-Jackson
$349Delta
Wed, May 12 - Sun, May 16
Delta Logo
3:25 pm - 8:06 pmROA  Roanoke-JAN Jackson-Evers Intl
5h 41m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:59 pm - 12:23 amJAN  Jackson-Evers Intl-ROA Roanoke
4h 24m1 stop Atlanta Hartsfield-Jackson
$349Delta
Fri, May 7 - Wed, May 12
Delta Logo
6:00 am - 10:05 amROA  Roanoke-JAN Jackson-Evers Intl
5h 05m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:59 pm - 12:23 amJAN  Jackson-Evers Intl-ROA Roanoke
4h 24m1 stop Atlanta Hartsfield-Jackson
$349Delta
Fri, Feb 5 - Mon, Feb 8
Delta Logo
11:27 am - 2:17 pmROA  Roanoke-JAN Jackson-Evers Intl
3h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:14 pm - 12:16 amJAN  Jackson-Evers Intl-ROA Roanoke
4h 02m1 stop Atlanta Hartsfield-Jackson
$349Delta
Mon, Jan 18 - Mon, Jan 18
American Airlines Logo
7:40 am - 11:47 amROA  Roanoke-JAN Jackson-Evers Intl
5h 07m1 stop Charlotte Douglas
American Airlines Logo
5:53 pm - 10:53 pmJAN  Jackson-Evers Intl-ROA Roanoke
4h 00m1 stop Charlotte Douglas
$409American Airlines
Mon, Jan 18 - Wed, Jan 20
American Airlines Logo
12:22 pm - 5:23 pmROA  Roanoke-JAN Jackson-Evers Intl
6h 01m1 stop Charlotte Douglas
American Airlines Logo
12:35 pm - 5:49 pmJAN  Jackson-Evers Intl-ROA Roanoke
4h 14m1 stop Charlotte Douglas
$449American Airlines
Booking Insights

Price, demand and travel trends for Roanoke to Mississippi flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Roanoke to Mississippi recently?

The cheapest fare from Roanoke to Mississippi in the last week was $349 round-trip, to Jackson-Evers Intl (JAN).

How do fares into airports in Mississippi compare?

According to KAYAK data from the last 12 months, the cheapest airports to fly into Mississippi from Roanoke are:

• Columbus Golden Triangle Reg. (GTR) (avg. price $316)
• Gulfport Biloxi Regional (GPT) (avg. price $398)
• Jackson-Evers Intl (JAN) (avg. price $438)

What's the best time of day to fly from Roanoke to Mississippi?

It's cheapest to fly to Mississippi in the evening with average prices of $398. The afternoon is the most expensive time to fly, with average prices of $478.

Find deals

Key details for Roanoke to Mississippi flights

Low season

March

Cheapest flight

$349
Beat the crowds with an average 52% drop in travelers.
The most popular month to fly with an average 43% increase in travelers.
Round-trip flight from Roanoke to Jackson

Your Roanoke to Mississippi flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Roanoke to Mississippi?

    Fares from Roanoke to Mississippi are around their usual level right now. A round-trip under $346 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch fare changes.

  • How much should I budget for a flight from Roanoke to Mississippi?

    Over the past 12 months, round-trip fares from Roanoke to Mississippi have typically cost between $346 and $502.

  • What are the main airports serving Mississippi?

    There are 14 airports in Mississippi. 50% of KAYAK users choose Gulfport Biloxi Regional (GPT) as their arrival airport, while 33% choose Jackson-Evers Intl (JAN).

  • Which airlines fly nonstop from Roanoke to Mississippi?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Roanoke to Mississippi. However, Delta offers a one-stop option.

  • Which destinations in Mississippi can I fly nonstop from Roanoke?

    Based on the flight schedule for the next 3 months, there are no nonstop flights from Roanoke to Mississippi. The most popular destination you can reach with one stop is Gulfport.

  • Which cabin classes are available from Roanoke to Mississippi?

    On flights from Roanoke to Mississippi you can only book Economy Class.

Your guide to booking Roanoke to Mississippi flights

Get tips on when to book, when to fly and what to know before your trip.
  • Flexible with your dates? Fly in November to save some money. It's typically the cheapest month on this route, while flights in June will cost you the most.
  • Fly out on a Thursday to get the cheapest fares. Avoid Sunday flights, which are about 330% more expensive.
  • If you're watching your budget, fly into Columbus Golden Triangle Reg. (GTR) which has the lowest average airfare in the region. Just remember to budget for any onward travel by bus, car or domestic flight.
  • Start your trip in Biloxi, the most popular destination in Mississippi. From there, it's easy to continue on to other popular spots such as Gulfport, Jackson and Hattiesburg.

Reviews of the top airline flying from Roanoke to Mississippi

 
Need help choosing which airline to fly with from Roanoke to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8719 reviews
7.8Entertainment
7.8Comfort
7.2Food
8.5Crew
8.1Boarding
Airline reviews

Everything went smoothly, WiFi connection was strong. Time to upgrade the regional planes, we are all on top of each other. No room to comfortably do anything.

8.0 ExcellentElizabeth, Nov 2026
Read more Delta reviews

Everything went smoothly, WiFi connection was strong. Time to upgrade the regional planes, we are all on top of each other. No room to comfortably do anything.

Very good- all went as planned. Flight was on time. Seating was a little sub , as always. Snacks and entertainment were basic. We arrived on time- no problems.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

The boarding process doesn't make sense since some people that will sit behind your rows are boarded before you and then they take up the luggage space above your head. I then have to wait for people to get off the plane before I can go back to get my luggage.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

They made us board and then deboard due to mechanical issue which delayed the departure by almost 2 hours and we barely made our connecting flight. These quality checks should've been done before boarding not after.

My Flight was cancelled and there was no other options available for me to Travel on that date and my options for the next day was all connecting flights that would have me in the airports all day before reaching my destination

Atlanta boarding crew at gate were filled with arrogance and were disrespectful. In flight crew showed indifference to the needs of passengers. This is about the flight from ATL to BDL.

They were 2 hours late departing with no explanation. I missed my connection, was rebooked not in correct seating that I paid for. Over all of was horrible. I now know why I've not flown Delta since 2018

More options for your flight from Roanoke to Mississippi

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