$260 Find Cheap Flights from Roanoke to Mississippi

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to Mississippi departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mississippi

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to Mississippi, as well as popular online travel agencies
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Cheap Flights from Roanoke to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$329
Memphis
Memphis1 stop$329
Jackson
Jackson1 stop$329
Memphis
Memphis1 stop$329

Book Cheap Roanoke to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to Mississippi

Fri, May 29 - Mon, Jun 1
Delta Logo
6:00 am - 8:54 am
ROA
-
JAN
3h 54m
1 stop
Delta Logo
7:23 pm - 12:34 am
JAN
-
ROA
4h 11m
1 stop
$329Delta
Sun, May 10 - Sat, May 16
Delta Logo
7:05 am - 12:12 pm
ROA
-
MEM
6h 07m
1 stop
Delta Logo
5:54 pm - 10:58 pm
MEM
-
ROA
4h 04m
1 stop
$329Delta
Sun, May 10 - Sat, May 16
Delta Logo
6:00 am - 9:04 am
ROA
-
MEM
4h 04m
1 stop
Delta Logo
5:54 pm - 10:58 pm
MEM
-
ROA
4h 04m
1 stop
$334Delta
Tue, May 5 - Sat, May 9
American Airlines Logo
12:58 pm - 7:06 pm
ROA
-
MEM
7h 08m
2 stops
American Airlines Logo
3:23 pm - 10:26 pm
MEM
-
ROA
6h 03m
1 stop
$344American Airlines
Fri, Sep 25 - Sun, Sep 27
American Airlines Logo
3:10 pm - 9:37 pm
ROA
-
MEM
7h 27m
1 stop
American Airlines Logo
5:34 am - 10:30 am
MEM
-
ROA
3h 56m
1 stop
$399American Airlines
Fri, Sep 18 - Mon, Sep 21
United Airlines Logo
5:47 pm - 9:57 pm
ROA
-
MEM
5h 10m
1 stop
United Airlines Logo
2:39 pm - 11:43 pm
MEM
-
ROA
8h 04m
2 stops
$412United Airlines
Sat, May 16 - Tue, May 19
United Airlines Logo
6:45 am - 10:54 am
ROA
-
MEM
5h 09m
1 stop
United Airlines Logo
11:10 am - 4:59 pm
MEM
-
ROA
4h 49m
1 stop
$417United Airlines
Sat, May 16 - Tue, May 19
American Airlines Logo
7:45 pm - 11:47 pm
ROA
-
MEM
5h 02m
1 stop
American Airlines Logo
6:47 am - 5:33 pm
MEM
-
ROA
9h 46m
2 stops
$433American Airlines
Wed, Sep 2 - Sat, Sep 5
United Airlines Logo
3:09 pm - 8:17 pm
ROA
-
MOB
6h 08m
1 stop
United Airlines Logo
9:30 am - 11:43 pm
MOB
-
ROA
13h 13m
2 stops
$454United Airlines
Fri, May 29 - Mon, Jun 1
American Airlines Logo
3:10 pm - 11:54 pm
ROA
-
JAN
9h 44m
2 stops
American Airlines Logo
4:21 pm - 11:47 pm
JAN
-
ROA
6h 26m
1 stop
$574American Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to Mississippi flights

Get data-powered insights and trends into flights from Roanoke to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to Mississippi were found on Delta ($329) and United Airlines ($412).

Good to know

Low seasonJuly
Cheapest flight$260
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Roanoke to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Roanoke to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Roanoke to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8430 reviews
7.8Entertainment
7.2Food
7.9Comfort
8.1Boarding
8.5Crew
Airline reviews

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

4.0 OkayAnonymous, Apr 2026
MYR - ATL
Read more Delta reviews

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

Very old plane with no inflight entertainment. I purchased the internet pass and it was nearly unusable.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

Short trip, no food and therefore no expectation for much interaction with staff who were pleasant and professional. My critique is on comfort of the seats. Exit rows and comfort seats do not provide enough personal space for 3 side-by-side seats, especially when in the middle row. Some passengers are not considerate of the middle seat and there should be signs that state something to the effect of: "please consider giving middle seats use of the armrests."

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

Original flight was on time, then late, then changed gates...4 times. Once our newest plane came in, it was fine.

Everything you need to know for your flight from Roanoke to Mississippi

Information on your arrival and departure airports