$269 Find Cheap Flights from Roanoke to Mississippi - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to Mississippi departing on 7/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Roanoke to Mississippi

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Jackson
Jackson1 stop$369
Memphis
Memphis1 stop$309
Jackson
Jackson1 stop$369
Memphis
Memphis1 stop$309

Book Cheap Roanoke to Mississippi Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to Mississippi that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to Mississippi

Thu, Jul 30 - Mon, Aug 3
United Airlines Logo
5:52 pm - 11:21 pm
ROA
-
MEM
6h 29m
1 stop
United Airlines Logo
2:22 pm - 9:03 pm
MEM
-
ROA
5h 41m
1 stop
$309United Airlines
Thu, Aug 20 - Mon, Aug 24
United Airlines Logo
5:50 pm - 11:18 pm
ROA
-
MEM
6h 28m
1 stop
United Airlines Logo
7:15 am - 7:07 pm
MEM
-
ROA
10h 52m
2 stops
$314United Airlines
Thu, Aug 20 - Mon, Aug 24
United Airlines Logo
6:15 am - 3:21 pm
ROA
-
MEM
10h 06m
2 stops
United Airlines Logo
7:15 am - 7:07 pm
MEM
-
ROA
10h 52m
2 stops
$319United Airlines
Wed, Jul 22 - Wed, Jul 29
Delta Logo
6:00 am - 10:32 am
ROA
-
MEM
5h 32m
1 stop
Delta Logo
5:52 pm - 12:25 am
MEM
-
ROA
5h 33m
1 stop
$345Delta
Sat, Jul 18 - Thu, Jul 23
Delta Logo
7:00 am - 12:32 pm
ROA
-
MEM
6h 32m
1 stop
Delta Logo
7:08 pm - 12:25 am
MEM
-
ROA
4h 17m
1 stop
$362Delta
Thu, Jul 16 - Mon, Jul 20
Delta Logo
6:00 am - 8:29 am
ROA
-
JAN
3h 29m
1 stop
Delta Logo
7:10 pm - 12:25 am
JAN
-
ROA
4h 15m
1 stop
$369Delta
Thu, Jul 16 - Mon, Jul 20
American Airlines Logo
7:53 pm - 11:48 pm
ROA
-
JAN
4h 55m
1 stop
American Airlines Logo
5:00 am - 2:24 pm
JAN
-
ROA
8h 24m
2 stops
$567American Airlines
Fri, Jul 17 - Tue, Jul 21
American Airlines Logo
6:48 am - 12:17 pm
ROA
-
MOB
6h 29m
1 stop
American Airlines Logo
7:15 am - 5:37 pm
MOB
-
ROA
9h 22m
2 stops
$596American Airlines
Thu, Jul 16 - Mon, Jul 20
American Airlines Logo
3:10 pm - 11:48 pm
ROA
-
JAN
9h 38m
2 stops
American Airlines Logo
5:00 am - 2:24 pm
JAN
-
ROA
8h 24m
2 stops
$657American Airlines
Sun, Jul 19 - Mon, Jul 20
Delta Logo
7:57 pm - 11:09 pm
ROA
-
JAN
4h 12m
1 stop
Delta Logo
7:10 pm - 12:25 am
JAN
-
ROA
4h 15m
1 stop
$727Delta
Booking Insights

KAYAK's insights & trends for Roanoke to Mississippi flights

Get data-powered insights and trends into flights from Roanoke to Mississippi to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to Mississippi?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Roanoke to Mississippi were found on United Airlines ($309) and Delta ($345).

Good to know

Low seasonFebruary
Cheapest flight$269
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Roanoke to Memphis

FAQs - booking Mississippi flights

  • How does KAYAK find such low prices on flights from Roanoke to Mississippi?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to Mississippi.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to Mississippi?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to Mississippi is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to Mississippi?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to Mississippi with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to Mississippi?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to Mississippi up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Roanoke to Mississippi

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to Mississippi. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to Mississippi? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8453 reviews
7.8Comfort
8.1Boarding
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

10.0 ExcellentJOSEPH, Jun 2026
RIC - ATL
Read more Delta reviews

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

The boarding process doesn't make sense since some people that will sit behind your rows are boarded before you and then they take up the luggage space above your head. I then have to wait for people to get off the plane before I can go back to get my luggage.

Good seat comfort ORF to ATL. Bad seat ATL to SEA (terrible lumbar support, hard, ouch)..

They made us board and then deboard due to mechanical issue which delayed the departure by almost 2 hours and we barely made our connecting flight. These quality checks should've been done before boarding not after.

My Flight was cancelled and there was no other options available for me to Travel on that date and my options for the next day was all connecting flights that would have me in the airports all day before reaching my destination

Atlanta boarding crew at gate were filled with arrogance and were disrespectful. In flight crew showed indifference to the needs of passengers. This is about the flight from ATL to BDL.

They were 2 hours late departing with no explanation. I missed my connection, was rebooked not in correct seating that I paid for. Over all of was horrible. I now know why I've not flown Delta since 2018

Crew wasn’t attentive. We didn’t see our flight attendant for stretches of time and inflight beverage service was cut short (as it always is on this route).

Boarding was slow again. Too many people with too much luggage.

They did not offer coffee on a 7am flight…awful!!

Excellent service. Flight attendance like Jessica,, on our flight, is a reason I wouldn’t mind flying through British Airways again. Jessica,, was very courteous and helpful.

The flight took off an hour late which made the connection concerning

Flight was delayed. No urgency by American Airlines team to assist those with connecting flights. It was basically you are on your own to run through the terminals to try and make your connection. Thanks, Mary

Never had such a lazy first class attendant. Literally spent 60%+ of the flight playing games on her personal phone making up excuses of why she was unavailable.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

RIC Staff was not enough. Elderly passengers had to wait 30 minutes to deplane, so we could board and still had to walk as no chairs were provided. And, passenger in front of my seat assignment rammed seat against my legs entire flight time. Was mildly bruised and left thigh still sore.

The flight had a delay that made me being in a real rush to take the second flight. The delay was almost for 2 hours. They moved us from gate to gate in 4 times. Once I arrived to Philadelphia, I got to run thorough all the airport, as the train was already closed by that time. So I got sick with asthma for all the running I had to do. And I was the last one to board, when it was almost closed. So irresponsable with the people

American was having a problem with their kiosks when I arrived which made the check-in and bag drop process unusually long. Additionally, they only had one person working check-in. Eventually, the kiosks were fixed and everything else went smoothly.

The flight was short. However, my bag was delayed and was put on another flight.

Everything you need to know for your flight from Roanoke to Mississippi

Information on your arrival and departure airports